PT1984021T - Bactérias gram-negativas não tóxicas viáveis - Google Patents
Bactérias gram-negativas não tóxicas viáveisInfo
- Publication number
- PT1984021T PT1984021T PT77183267T PT07718326T PT1984021T PT 1984021 T PT1984021 T PT 1984021T PT 77183267 T PT77183267 T PT 77183267T PT 07718326 T PT07718326 T PT 07718326T PT 1984021 T PT1984021 T PT 1984021T
- Authority
- PT
- Portugal
- Prior art keywords
- negative bacteria
- gram negative
- viable non
- toxic gram
- toxic
- Prior art date
Links
- 241000894006 Bacteria Species 0.000 title 1
- 231100000252 nontoxic Toxicity 0.000 title 1
- 230000003000 nontoxic effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/025—Enterobacteriales, e.g. Enterobacter
- A61K39/0258—Escherichia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/36—Adaptation or attenuation of cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biophysics (AREA)
- Oncology (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Cell Biology (AREA)
- Plant Pathology (AREA)
- Communicable Diseases (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US76031406P | 2006-01-19 | 2006-01-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT1984021T true PT1984021T (pt) | 2016-11-02 |
Family
ID=38288246
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT77183267T PT1984021T (pt) | 2006-01-19 | 2007-01-19 | Bactérias gram-negativas não tóxicas viáveis |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US8303964B2 (pt) |
| EP (1) | EP1984021B1 (pt) |
| JP (1) | JP5279510B2 (pt) |
| CN (1) | CN101472604B (pt) |
| AU (1) | AU2007207519B2 (pt) |
| CA (1) | CA2637903C (pt) |
| DK (1) | DK1984021T3 (pt) |
| ES (1) | ES2589314T3 (pt) |
| HU (1) | HUE030981T2 (pt) |
| IL (1) | IL192882A0 (pt) |
| PL (1) | PL1984021T3 (pt) |
| PT (1) | PT1984021T (pt) |
| WO (1) | WO2007084633A2 (pt) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG2014015010A (en) * | 2008-04-30 | 2014-05-29 | Gradalis Inc | Highly pure plasmid dna preparations and processes for preparing the same |
| KR101488902B1 (ko) * | 2009-10-08 | 2015-02-03 | 주식회사이언메딕스 | 실내 공기유래 세포밖 소포체를 포함하는 조성물 및 이의 용도 |
| DK2545162T3 (en) | 2010-03-12 | 2017-02-06 | Res Corp Tech | Viable Gram Negative Bacteria Lacking Outer MEMBRANE AGONISTS FOR TLR4 / MD-2 |
| WO2013025248A1 (en) * | 2011-08-12 | 2013-02-21 | Mello Biotechnology, Inc. | Inducable expression from the eukaryotic pol -2 promoter in prokaryotes |
| EP2753688B1 (en) * | 2011-09-09 | 2018-06-20 | Research Corporation Technologies, Inc. | Viable gram negative bacteria with reduced proteolytic activity lacking outer membrane agonists of tlr4/md-2 |
| EP2833911A4 (en) | 2012-04-06 | 2016-07-13 | Univ Cornell | SUB-VACCINE VACCINATING PLATFORM FOR ROBUST HUMORAL AND CELLULAR IMMUNE RESPONSES |
| US10196662B2 (en) * | 2012-08-10 | 2019-02-05 | Mello Biotechnology, Inc. | Composition for producing microRNA precursors as drugs for enhancing wound healing and production method of the microRNA precursors |
| DK2941258T3 (da) | 2013-01-02 | 2019-12-16 | Decoy Biosystems Inc | Sammensætninger og fremgangsmåder til behandling af cancer ved anvendelse af bakterier |
| US10358667B2 (en) | 2013-03-07 | 2019-07-23 | University Of Maryland, Baltimore | Immunotherapeutic potential of modified lipooligosaccharides/lipid A |
| CN104388368B (zh) * | 2014-10-30 | 2017-02-15 | 四川农业大学 | 一株低内毒素大肠杆菌原核表达工程菌突变株及构建方法 |
| KR101761348B1 (ko) | 2016-01-06 | 2017-07-26 | 한국과학기술연구원 | 헥사 아실화된 모노포스포릴 지질 a를 생산하는 세균, 및 이를 이용한 헥사 아실화된 모노포스포릴 지질 a 생산 방법 |
| WO2018023000A1 (en) * | 2016-07-29 | 2018-02-01 | The Regents Of The University Of Michigan | Recombinant gram negative bacteria and methods of generating and utilizing same |
| DK3713586T5 (da) | 2017-11-20 | 2024-08-26 | Codex Dna Inc | Vibrio sp. organismer med modificeret lipopolysaccharid |
| KR102212335B1 (ko) * | 2018-03-21 | 2021-02-04 | ㈜로제타엑소좀 | 박테리아 유래이고 독성이 감소된 세포밖 소포체 및 이의 용도 |
| CN110878276B (zh) * | 2018-09-06 | 2021-06-29 | 清华大学 | 一种通过外膜缺陷制备革兰氏阴性细菌感受态细胞的方法 |
| CA3155372A1 (en) * | 2019-10-28 | 2021-05-06 | Sharief Barends | Microbial host cells for the production of heterologous cyanuric acid hydrolases and biuret hydrolases |
| WO2021160829A1 (en) | 2020-02-14 | 2021-08-19 | Inbiose N.V. | Viable bacterial host cell |
| CN111500600B (zh) * | 2020-04-22 | 2021-11-19 | 武汉艾默佳华生物科技有限公司 | 3-甾酮-1,2-脱氢酶及其基因序列和应用 |
| CN112161976B (zh) * | 2020-09-27 | 2022-11-08 | 郑州安图生物工程股份有限公司 | 检测大肠埃希菌和/或志贺菌的底物组合、检测试剂及检测试剂盒 |
| CN116376791A (zh) * | 2023-03-16 | 2023-07-04 | 恒敬合创生物医药（浙江）有限公司 | 一种高密度发酵的低内毒素大肠杆菌及其应用 |
| WO2024206940A1 (en) | 2023-03-31 | 2024-10-03 | Kano Therapeutics Inc. | Engineered cssdna production hosts and phagemids |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5106184A (en) * | 1990-08-13 | 1992-04-21 | Eye Research Institute Of Retina Foundation | Retinal laser doppler apparatus having eye tracking system |
| US6558677B2 (en) | 1996-10-15 | 2003-05-06 | Wendell D. Zollinger | Vaccine against gram negative bacteria |
| WO1998053851A1 (en) * | 1997-05-28 | 1998-12-03 | University Of Iowa Research Foundation | Laft mutants of pathogenic gram-negative bacteria |
| DK0991761T3 (da) * | 1997-08-21 | 2008-05-19 | Nederlanden Staat | Hidtil ukendte mutaner af gramnegative mucosale bakterier og anvendelse deraf i vacciner |
| CN1213768C (zh) * | 1998-04-27 | 2005-08-10 | 联邦高等教育系统坦普尔大学 | 治疗内毒素血症的方法 |
| GB0130123D0 (en) * | 2001-12-17 | 2002-02-06 | Microbiological Res Agency | Outer membrane vesicle vaccine and its preparation |
| WO2003079995A2 (en) * | 2002-03-20 | 2003-10-02 | Emory University | Neisseria mutants, lipooligosaccharides and immunogenic compositions |
| CA2550927A1 (en) * | 2003-12-23 | 2005-07-14 | Glaxosmithkline Biologicals S.A. | A gram negative bacterium with reduced lps level in the outer membrane and use thereof for treating gram negative bacterial infection |
-
2007
- 2007-01-19 AU AU2007207519A patent/AU2007207519B2/en active Active
- 2007-01-19 JP JP2008551397A patent/JP5279510B2/ja active Active
- 2007-01-19 DK DK07718326.7T patent/DK1984021T3/en active
- 2007-01-19 CA CA2637903A patent/CA2637903C/en active Active
- 2007-01-19 PL PL07718326T patent/PL1984021T3/pl unknown
- 2007-01-19 PT PT77183267T patent/PT1984021T/pt unknown
- 2007-01-19 WO PCT/US2007/001367 patent/WO2007084633A2/en active Application Filing
- 2007-01-19 ES ES07718326.7T patent/ES2589314T3/es active Active
- 2007-01-19 US US11/655,413 patent/US8303964B2/en active Active
- 2007-01-19 CN CN200780008031XA patent/CN101472604B/zh active Active
- 2007-01-19 EP EP07718326.7A patent/EP1984021B1/en active Active
- 2007-01-19 HU HUE07718326A patent/HUE030981T2/en unknown
-
2008
- 2008-07-17 IL IL192882A patent/IL192882A0/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| PL1984021T3 (pl) | 2017-02-28 |
| CA2637903C (en) | 2014-04-15 |
| HUE030981T2 (en) | 2017-06-28 |
| CA2637903A1 (en) | 2007-07-26 |
| AU2007207519A1 (en) | 2007-07-26 |
| WO2007084633A3 (en) | 2007-12-06 |
| ES2589314T3 (es) | 2016-11-11 |
| IL192882A0 (en) | 2009-02-11 |
| JP5279510B2 (ja) | 2013-09-04 |
| EP1984021A2 (en) | 2008-10-29 |
| CN101472604A (zh) | 2009-07-01 |
| US8303964B2 (en) | 2012-11-06 |
| JP2009523810A (ja) | 2009-06-25 |
| US20100272758A1 (en) | 2010-10-28 |
| EP1984021B1 (en) | 2016-08-10 |
| DK1984021T3 (en) | 2016-12-05 |
| AU2007207519B2 (en) | 2010-05-20 |
| EP1984021A4 (en) | 2009-06-24 |
| WO2007084633A2 (en) | 2007-07-26 |
| CN101472604B (zh) | 2013-11-06 |
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