PT1962913E - Radioimunoconjugado para cd66 humano para o tratamento de mieloma múltiplo - Google Patents

Radioimunoconjugado para cd66 humano para o tratamento de mieloma múltiplo Download PDF

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Publication number
PT1962913E
PT1962913E PT68292242T PT06829224T PT1962913E PT 1962913 E PT1962913 E PT 1962913E PT 68292242 T PT68292242 T PT 68292242T PT 06829224 T PT06829224 T PT 06829224T PT 1962913 E PT1962913 E PT 1962913E
Authority
PT
Portugal
Prior art keywords
radioimmunoconjugate
human
treatment
multiple myeloma
myeloma
Prior art date
Application number
PT68292242T
Other languages
English (en)
Inventor
Klaus Bosslet
Ivan Benes
Kim Orchard
Ladislav Droz
Original Assignee
Therapharm Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Therapharm Gmbh filed Critical Therapharm Gmbh
Publication of PT1962913E publication Critical patent/PT1962913E/pt

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
    • A61K51/1045—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against animal or human tumor cells or tumor cell determinants
    • A61K51/1069—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against animal or human tumor cells or tumor cell determinants the tumor cell being from blood cells, e.g. the cancer being a myeloma
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PT68292242T 2005-11-30 2006-11-30 Radioimunoconjugado para cd66 humano para o tratamento de mieloma múltiplo PT1962913E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US74064705P 2005-11-30 2005-11-30

Publications (1)

Publication Number Publication Date
PT1962913E true PT1962913E (pt) 2014-01-30

Family

ID=37989009

Family Applications (1)

Application Number Title Priority Date Filing Date
PT68292242T PT1962913E (pt) 2005-11-30 2006-11-30 Radioimunoconjugado para cd66 humano para o tratamento de mieloma múltiplo

Country Status (7)

Country Link
US (1) US9072797B2 (pt)
EP (1) EP1962913B1 (pt)
AU (1) AU2006319361B2 (pt)
CA (1) CA2657452C (pt)
ES (1) ES2444405T3 (pt)
PT (1) PT1962913E (pt)
WO (1) WO2007062855A2 (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011144744A1 (en) 2010-05-20 2011-11-24 Therapharm Gmbh Targeted radioactive compound for human cd66 for the treatment of disorders
EP3351271A1 (en) * 2017-01-23 2018-07-25 TheraPharm GmbH Radioimmunoconjugate for use in treating bone marrow associated diseases
PE20251671A1 (es) 2022-03-15 2025-06-30 Compugen Ltd Anticuerpos antagonistas de il-18bp y su uso en monoterapia y terapia de combinacion en el tratamiento del cancer
CN116459351B (zh) * 2023-03-03 2025-06-27 浙江大学 一种基于中性粒细胞的骨髓靶向给药载体及应用
TW202515608A (zh) 2023-06-26 2025-04-16 以色列商坎布根有限公司 Ｉｌ—１８ｂｐ拮抗抗體及其於癌症治療之單一療法及組合療法的用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19911329A1 (de) * 1998-03-27 2000-09-21 Benes Ivan Friedrich Humantherapeutisch anwendbares Radioimmunkonjugat und Verfahren zu seiner Herstellung
JP3888971B2 (ja) * 2000-08-08 2007-03-07 イムノメディクス， インコーポレイテッド 慢性骨髄性白血病の免疫療法
US7541440B2 (en) 2002-09-30 2009-06-02 Immunomedics, Inc. Chimeric, human and humanized anti-granulocyte antibodies and methods of use

Also Published As

Publication number Publication date
ES2444405T3 (es) 2014-02-24
AU2006319361A1 (en) 2007-06-07
AU2006319361B2 (en) 2011-09-22
CA2657452A1 (en) 2007-06-07
US9072797B2 (en) 2015-07-07
WO2007062855A2 (en) 2007-06-07
US20100183505A1 (en) 2010-07-22
CA2657452C (en) 2018-07-17
WO2007062855A3 (en) 2008-01-10
EP1962913A2 (en) 2008-09-03
EP1962913B1 (en) 2013-12-04

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