PT1362600E - Topical use of nf-kb decoys for treating atopic dermatitis - Google Patents

Topical use of nf-kb decoys for treating atopic dermatitis Download PDF

Info

Publication number
PT1362600E
PT1362600E PT02711351T PT02711351T PT1362600E PT 1362600 E PT1362600 E PT 1362600E PT 02711351 T PT02711351 T PT 02711351T PT 02711351 T PT02711351 T PT 02711351T PT 1362600 E PT1362600 E PT 1362600E
Authority
PT
Portugal
Prior art keywords
nf
atopic dermatitis
topical use
treating atopic
decoys
Prior art date
Application number
PT02711351T
Other languages
Portuguese (pt)
Inventor
Ryuichi Morishita
Motokuni Aoki
Toshio Ogihara
Yasufumi Kaneda
Hiroshige Nakamura
Original Assignee
Anges Mg Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to JP2001044350 priority Critical
Application filed by Anges Mg Inc filed Critical Anges Mg Inc
Publication of PT1362600E publication Critical patent/PT1362600E/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088Compounds having three or more nucleosides or nucleotides
    • A61K31/711Natural deoxyribonucleic acids, i.e. containing only 2'-deoxyriboses attached to adenine, guanine, cytosine or thymine and having 3'-5' phosphodiester links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/10Type of nucleic acid
    • C12N2310/13Decoys
PT02711351T 2001-02-20 2002-02-06 Topical use of nf-kb decoys for treating atopic dermatitis PT1362600E (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2001044350 2001-02-20

Publications (1)

Publication Number Publication Date
PT1362600E true PT1362600E (en) 2008-07-09

Family

ID=18906362

Family Applications (1)

Application Number Title Priority Date Filing Date
PT02711351T PT1362600E (en) 2001-02-20 2002-02-06 Topical use of nf-kb decoys for treating atopic dermatitis

Country Status (11)

Country Link
US (2) US9012417B2 (en)
EP (2) EP1362600B1 (en)
JP (2) JP3778357B2 (en)
AT (1) AT390938T (en)
CY (1) CY1108165T1 (en)
DE (1) DE60225899T2 (en)
DK (1) DK1362600T3 (en)
ES (1) ES2307733T3 (en)
PT (1) PT1362600E (en)
TW (1) TWI308492B (en)
WO (1) WO2002066070A1 (en)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT732929E (en) * 1993-10-29 2008-08-26 Brigham & Womens Hospital Therapeutic use of cis-element decoys in vivo
PT1362600E (en) 2001-02-20 2008-07-09 Anges Mg Inc Topical use of nf-kb decoys for treating atopic dermatitis
DE10148886A1 (en) * 2001-10-04 2003-04-30 Avontec Gmbh Inhibition of STAT-1
JP4594233B2 (en) * 2003-05-09 2010-12-08 アンジェスMg株式会社 Chemical is accommodated needleless syringe
AU2003252493A1 (en) * 2003-07-09 2005-01-28 Anges Mg, Inc. Pharmaceutical composition containing decoy and method of using the same
CA2537184A1 (en) * 2003-08-29 2005-03-10 Anges Mg, Inc. Gene therapy for skin disorders using needleless syringes
WO2005056020A2 (en) * 2003-12-02 2005-06-23 Corgentech, Inc. Nf-kb oligonucleotide decoy molecules
WO2005062854A2 (en) * 2003-12-19 2005-07-14 University Of Cincinnati Polyamides for nucleic acid delivery
EP1799271A4 (en) * 2004-09-21 2010-05-05 Anesiva Inc Delivery of polynucleotides
US8067384B2 (en) 2004-10-22 2011-11-29 Anges Mg, Inc. Chimera (double) decoy
US20060258604A1 (en) * 2005-05-10 2006-11-16 Warren Strober Compositions and methods for the treatment of inflammatory bowel disease utilizing NF-kappaB decoy polynucleotides
US20090214630A1 (en) * 2005-05-10 2009-08-27 Warren Strober Compositions and Methods for the Treatment of Inflammatory Bowel Disease Utilizing NF-KappaB Decoy Polynucleotides
US20090143319A1 (en) * 2005-06-06 2009-06-04 Angesmg, Inc. Transcription factor decoy
US20100035793A1 (en) * 2005-07-27 2010-02-11 Cheh Peng Lim Modulators
JPWO2007072909A1 (en) * 2005-12-22 2009-06-04 アンジェスMg株式会社 New oligonucleotides and NF-κB decoy made from it
CA2634291A1 (en) * 2005-12-22 2007-06-28 Institut De Cardiologie De Montreal Transcription factor decoy oligodeoxynucleotides having multiple cis elements
JP4602298B2 (en) * 2006-08-31 2010-12-22 アンジェスMg株式会社 Pharmaceutical preparations
JP5384120B2 (en) 2007-02-16 2014-01-08 アンジェスMg株式会社 Therapeutic agent for periodontal diseases and alveolar bone defects caused by surgery
US20080249044A1 (en) * 2007-04-03 2008-10-09 Masaya Tanaka Nucleic acid external skin formulation
EP3199635B1 (en) 2007-05-11 2019-02-06 Adynxx, Inc. Gene expression and pain
EP2266626B1 (en) * 2008-03-28 2014-06-18 AnGesMG, Inc. Composition for external application comprising transcription factor decoy as active ingredient
WO2013170086A2 (en) 2012-05-10 2013-11-14 Adynxx, Inc. Formulations for the delivery of active ingredients
CN106661578A (en) 2014-08-15 2017-05-10 埃迪恩克斯股份有限公司 Oligonucleotide decoys for the treatment of pain

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2361756A (en) * 1942-03-31 1944-10-31 George W Fiero Ointments and the like
JPS6323971B2 (en) * 1980-03-27 1988-05-18 Mitsubishi Chem Ind
US4301145A (en) * 1980-07-28 1981-11-17 Cestari Joseph E Antiseptic skin cream
US6410516B1 (en) 1986-01-09 2002-06-25 President & Fellows Of Harvard College Nuclear factors associated with transcriptional regulation
JPH05331066A (en) * 1992-05-25 1993-12-14 Toko Yakuhin Kogyo Kk Composition for treatment of acne vulgaris
PT732929E (en) * 1993-10-29 2008-08-26 Brigham & Womens Hospital Therapeutic use of cis-element decoys in vivo
US6399376B1 (en) * 1993-11-05 2002-06-04 Isis Pharmaceuticals, Inc. Modulation of vascular cell adhesive molecule expression through oligonucleotide interactions
EP0793963A4 (en) * 1994-10-24 2001-12-12 Nikken Chemicals Co Ltd Percutaneously administrable preparation
ES2285712T3 (en) * 1995-05-12 2007-11-16 Anges Mg, Inc. Medicament for the therapy and prophylaxis of various related diseases NF-kappa B.
CZ154898A3 (en) * 1995-11-21 1998-09-16 Icn Pharmaceuticals, Inc. Oligonucleotides for inhibiting growth of tumors mediated by il-8 and il-8 receptor
AT321882T (en) * 1997-07-01 2006-04-15 Isis Pharmaceuticals Inc Compositions and methods of administration of oligonucleotides via the esophagus
JP2001055331A (en) * 1999-06-11 2001-02-27 Toyama Chem Co Ltd Atopic dermatitis medicine
DE60131498T8 (en) * 2000-02-02 2009-01-29 Anges Mg Inc., Toyonaka VIRUS CASE VECTOR FOR THE GENE TRANSFER
DE10049549A1 (en) * 2000-10-06 2002-05-02 Markus Hecker Inhibitor of the transcription factor IFR-1, useful for treating e.g. transplant rejection and autoimmune disease, reduces expression of CD40
PT1362600E (en) 2001-02-20 2008-07-09 Anges Mg Inc Topical use of nf-kb decoys for treating atopic dermatitis
JPWO2003063911A1 (en) * 2002-02-01 2006-01-19 アンジェスMg株式会社 Pharmaceutical compositions and methods of use thereof comprising decoy
JP4971609B2 (en) 2004-08-27 2012-07-11 アンジェスMg株式会社 Nucleic acid skin preparation
JP2006111591A (en) 2004-10-15 2006-04-27 Anges Mg Inc Preparation for target-specifically delivering nucleic acid medicine inside cell

Also Published As

Publication number Publication date
JP4987022B2 (en) 2012-07-25
JP2009102428A (en) 2009-05-14
US20040162251A1 (en) 2004-08-19
EP1690544B1 (en) 2017-09-13
TWI308492B (en) 2009-04-11
AT390938T (en) 2008-04-15
EP1690544A3 (en) 2012-03-07
WO2002066070A1 (en) 2002-08-29
JP3778357B2 (en) 2006-05-24
CY1108165T1 (en) 2014-02-12
DE60225899D1 (en) 2008-05-15
EP1362600B1 (en) 2008-04-02
DE60225899T2 (en) 2009-04-09
DK1362600T3 (en) 2008-07-28
US20090105183A1 (en) 2009-04-23
JPWO2002066070A1 (en) 2004-06-17
EP1690544A2 (en) 2006-08-16
ES2307733T3 (en) 2008-12-01
US9012417B2 (en) 2015-04-21
EP1362600A1 (en) 2003-11-19
EP1362600A4 (en) 2005-09-21

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