PT1330451E - Benzimidazol-2-onas substituídas como antagonistas do receptor da vasopressina e moduladores do neuropéptido y - Google Patents
Benzimidazol-2-onas substituídas como antagonistas do receptor da vasopressina e moduladores do neuropéptido y Download PDFInfo
- Publication number
- PT1330451E PT1330451E PT01989314T PT01989314T PT1330451E PT 1330451 E PT1330451 E PT 1330451E PT 01989314 T PT01989314 T PT 01989314T PT 01989314 T PT01989314 T PT 01989314T PT 1330451 E PT1330451 E PT 1330451E
- Authority
- PT
- Portugal
- Prior art keywords
- neuropeptide
- modulators
- ones
- receptor antagonists
- vasopressin receptor
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
- A61P5/12—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH for decreasing, blocking or antagonising the activity of the posterior pituitary hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Diabetes (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Urology & Nephrology (AREA)
- Cardiology (AREA)
- Reproductive Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Vascular Medicine (AREA)
- Anesthesiology (AREA)
- Emergency Medicine (AREA)
- Psychiatry (AREA)
- Pulmonology (AREA)
- Gastroenterology & Hepatology (AREA)
- Child & Adolescent Psychology (AREA)
- Gynecology & Obstetrics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US24381700P | 2000-10-27 | 2000-10-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT1330451E true PT1330451E (pt) | 2008-03-13 |
Family
ID=22920251
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT01989314T PT1330451E (pt) | 2000-10-27 | 2001-10-23 | Benzimidazol-2-onas substituídas como antagonistas do receptor da vasopressina e moduladores do neuropéptido y |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP1330451B1 (pt) |
| JP (1) | JP2004517872A (pt) |
| AT (1) | ATE384711T1 (pt) |
| AU (1) | AU2002243419A1 (pt) |
| DE (1) | DE60132611T2 (pt) |
| DK (1) | DK1330451T3 (pt) |
| ES (1) | ES2300376T3 (pt) |
| PT (1) | PT1330451E (pt) |
| WO (1) | WO2002055514A2 (pt) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK1912976T3 (da) * | 2005-07-21 | 2009-01-26 | Hoffmann La Roche | Indol-3-YL-carbonyl-piperidin-benzoimidazolderivater som V1A-receptorantagonister |
| CN101528712B (zh) | 2006-08-26 | 2013-10-30 | Abbvie德国有限责任两合公司 | 取代的苯并咪唑酮衍生物、包含它们的药物以及其用途 |
| WO2013085954A1 (en) | 2011-12-06 | 2013-06-13 | Janssen Pharmaceutica Nv | Substituted piperidinyl-carboxamide derivatives useful as scd 1 inhibitors |
| US9102669B2 (en) | 2011-12-06 | 2015-08-11 | Janssen Pharmaceutica Nv | Substituted piperidinyl-pyridazinyl derivatives useful as SCD 1 inhibitors |
| MX2016001940A (es) * | 2013-08-19 | 2016-06-02 | Hoffmann La Roche | Antagonistas de v1a para tratar trastornos del sueño por cambio de fase. |
| CA3091951A1 (en) | 2018-03-01 | 2019-09-06 | Thomas Helledays Stiftelse For Medicinsk Forskning | Substituted benzodiazoles and use thereof in therapy |
| AU2022282786A1 (en) * | 2021-05-26 | 2023-12-07 | Sumitomo Pharma Co., Ltd. | Phenyl urea derivative |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3318900A (en) * | 1964-05-06 | 1967-05-09 | Janssen Pharmaceutica Nv | Derivatives of benzimidazolinyl piperidine |
| EP0714299B1 (en) * | 1993-07-16 | 2002-04-24 | Merck & Co. Inc. | Benzoxazinone and benzopyrimidinone piperidinyl tocolytic oxytocin receptor antagonists |
| US6057338A (en) * | 1997-04-04 | 2000-05-02 | Merck & Co., Inc. | Somatostatin agonists |
| AU5265599A (en) * | 1998-04-08 | 1999-11-01 | Takeda Chemical Industries Ltd. | Amine compounds, their production and their use as somatostatin receptor antagonists or agonists |
| EP1117662A1 (en) * | 1998-09-30 | 2001-07-25 | Merck Sharp & Dohme Limited | Benzimidazolinyl piperidines as cgrp ligands |
| GB9823873D0 (en) * | 1998-10-30 | 1998-12-30 | Pharmacia & Upjohn Spa | 2-ureido-thiazole derivatives,process for their preparation,and their use as antitumour agents |
-
2001
- 2001-10-23 EP EP01989314A patent/EP1330451B1/en not_active Expired - Lifetime
- 2001-10-23 DE DE60132611T patent/DE60132611T2/de not_active Expired - Fee Related
- 2001-10-23 AT AT01989314T patent/ATE384711T1/de not_active IP Right Cessation
- 2001-10-23 ES ES01989314T patent/ES2300376T3/es not_active Expired - Lifetime
- 2001-10-23 AU AU2002243419A patent/AU2002243419A1/en not_active Abandoned
- 2001-10-23 WO PCT/US2001/051108 patent/WO2002055514A2/en active IP Right Grant
- 2001-10-23 PT PT01989314T patent/PT1330451E/pt unknown
- 2001-10-23 DK DK01989314T patent/DK1330451T3/da active
- 2001-10-23 JP JP2002556183A patent/JP2004517872A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| DE60132611D1 (de) | 2008-03-13 |
| ATE384711T1 (de) | 2008-02-15 |
| EP1330451B1 (en) | 2008-01-23 |
| WO2002055514A3 (en) | 2002-11-21 |
| JP2004517872A (ja) | 2004-06-17 |
| ES2300376T3 (es) | 2008-06-16 |
| AU2002243419A1 (en) | 2002-07-24 |
| EP1330451A2 (en) | 2003-07-30 |
| DE60132611T2 (de) | 2009-02-19 |
| DK1330451T3 (da) | 2008-11-10 |
| WO2002055514A2 (en) | 2002-07-18 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MY135688A (en) | Novel substituted benzimidazol-2-ones as vasopressin receptor antagonists and neuropeptide y modulators | |
| SE0103644D0 (sv) | Therapeutic isoquinoline compounds | |
| WO2002055012A3 (en) | Therapeutic heterocyclic compounds | |
| SE0103649D0 (sv) | Therapeutic quinoline compounds | |
| BG106508A (en) | Alkylene diamine-substituted heterocycles | |
| WO2002055013A8 (en) | Therapeutic chromone compounds | |
| GEP20105073B (en) | Imidazo- and triazolopyridines as inhibitors of 11-beta hydroxysteroid dehydrogenase type i | |
| FI920217A (fi) | Angiotensin ii receptor blockerande 2,3,6-substituerade kinazolinoner. | |
| SE0103648D0 (sv) | Therapeutic quinolone compounds | |
| CA2469813A1 (en) | Heteroaryl substituted pyrazole modulators of metabotropic glutamate receptor-5 | |
| EA200600315A1 (ru) | Пиримидиновые соединения, их применение в качестве a-селективных антагонистов и способ их получения | |
| WO2003053922A3 (en) | Heteroaryl substituted imidazole modulators of metabotropic glutamate receptor-5 | |
| ATE230403T1 (de) | Einige amido- und ammo- substituierte benzylaminderivate: eine neue klasse von neuropeptid y1 spezifische ligande | |
| PT1330451E (pt) | Benzimidazol-2-onas substituídas como antagonistas do receptor da vasopressina e moduladores do neuropéptido y | |
| WO2000043398A3 (en) | Tricyclic benzodiazepines as vasopressin receptor antagonists | |
| EA200300064A1 (ru) | Карбоксамидные соединения и их применение в качестве антагонистов 11cby-рецептора человека | |
| IL153710A0 (en) | Nonpeptide substituted spirobenzoazepines as vasopressin antagonists | |
| HRP20080587T3 (en) | Tetrasubstituted imidazole derivatives as cannabinoid cb1 receptor modulators with a high cb1/cb2 receptor subtype selectivity | |
| RS20050930A (en) | Substituted spirobenzazepines | |
| ATE330605T1 (de) | Piperidin-2,6-dionpamoat-salze und ihre verwendung zur behanldung von stressbedingten affektiven st rungen | |
| PT1373218E (pt) | Derivados de imidazolilo úteis como ligandos do receptor h3 de histamina | |
| Kozai et al. | Synthesis and hypnotic activities of 4-thio analogues of N3-substituted uridines | |
| SE0103647D0 (sv) | Therapeutic chromone compounds | |
| SE0103650D0 (sv) | Therapeutic heterocyclic compounds | |
| WO2002048105A3 (en) | Aryloxy piperidinyl derivatives for the treatment of depression |