PT1152750E - Spontaneously dispersible n-benzoyl staurosporine compositions - Google Patents

Spontaneously dispersible n-benzoyl staurosporine compositions Download PDF

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Publication number
PT1152750E
PT1152750E PT00909165T PT00909165T PT1152750E PT 1152750 E PT1152750 E PT 1152750E PT 00909165 T PT00909165 T PT 00909165T PT 00909165 T PT00909165 T PT 00909165T PT 1152750 E PT1152750 E PT 1152750E
Authority
PT
Portugal
Prior art keywords
spontaneously dispersible
benzoyl staurosporine
compositions
staurosporine compositions
benzoyl
Prior art date
Application number
PT00909165T
Other languages
Portuguese (pt)
Inventor
Barbara Haeberlin
Graham Paul Matthews
Original Assignee
Novartis Ag
Novartis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10847896&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT1152750(E) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag, Novartis Pharma Gmbh filed Critical Novartis Ag
Publication of PT1152750E publication Critical patent/PT1152750E/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/553—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one oxygen as ring hetero atoms, e.g. loxapine, staurosporine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Vascular Medicine (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PT00909165T 1999-02-16 2000-02-14 Spontaneously dispersible n-benzoyl staurosporine compositions PT1152750E (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9903547.9A GB9903547D0 (en) 1999-02-16 1999-02-16 Organic compounds

Publications (1)

Publication Number Publication Date
PT1152750E true PT1152750E (en) 2009-08-07

Family

ID=10847896

Family Applications (1)

Application Number Title Priority Date Filing Date
PT00909165T PT1152750E (en) 1999-02-16 2000-02-14 Spontaneously dispersible n-benzoyl staurosporine compositions

Country Status (34)

Country Link
US (3) US20020061873A1 (en)
EP (1) EP1152750B1 (en)
JP (2) JP5057610B2 (en)
KR (2) KR100880859B1 (en)
CN (1) CN100367930C (en)
AR (2) AR022589A1 (en)
AT (1) ATE430554T1 (en)
AU (1) AU765776B2 (en)
BR (1) BRPI0008228B8 (en)
CA (1) CA2362277C (en)
CL (1) CL2009001682A1 (en)
CZ (1) CZ303979B6 (en)
DE (1) DE60042151D1 (en)
DK (1) DK1152750T3 (en)
EC (1) ECSP083351A (en)
ES (1) ES2326783T3 (en)
GB (1) GB9903547D0 (en)
HK (1) HK1045807B (en)
HU (1) HUP0105364A3 (en)
ID (1) ID30504A (en)
IL (3) IL144512A0 (en)
MY (1) MY128362A (en)
NO (1) NO331232B1 (en)
NZ (1) NZ513529A (en)
PE (1) PE20001499A1 (en)
PL (1) PL198330B1 (en)
PT (1) PT1152750E (en)
RU (1) RU2266121C2 (en)
SI (1) SI1152750T1 (en)
SK (1) SK286967B6 (en)
TR (1) TR200102385T2 (en)
TW (1) TWI240636B (en)
WO (1) WO2000048571A1 (en)
ZA (1) ZA200106677B (en)

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US7795246B2 (en) 1998-08-06 2010-09-14 Cephalon, Inc. Particle-forming compositions containing fused pyrrolocarbazoles
DK1372611T3 (en) * 2001-03-26 2006-09-18 Novartis Ag A pharmaceutical composition comprising low water solubility staurosporin, a surfactant and a water soluble polymer
KR20030094415A (en) 2001-05-16 2003-12-11 노파르티스 아게 Combination Comprising N-{5-[4-(4-Methyl-Piperazino-Methyl)-Benzoylamido]-2-Methylphenyl}-4-(3-Pyridyl)-2-Pyrimidine-Amine and a Chemotherapeutic Agent
WO2003037347A1 (en) 2001-10-30 2003-05-08 Novartis Ag Staurosporine derivatives as inhibitors of flt3 receptor tyrosine kinase activity
GB0206215D0 (en) 2002-03-15 2002-05-01 Novartis Ag Organic compounds
WO2004009056A1 (en) * 2002-07-23 2004-01-29 Novartis Ag Ophtalmic ointment composition comprising a drug, an ointment base and a solubiling/dispersing agent
US7842791B2 (en) 2002-12-19 2010-11-30 Nancy Jean Britten Dispersible pharmaceutical compositions
TWI324604B (en) * 2003-06-18 2010-05-11 Novartis Ag New use of staurosporine derivatives
GB0512324D0 (en) 2005-06-16 2005-07-27 Novartis Ag Organic compounds
GB0419159D0 (en) * 2004-08-27 2004-09-29 Novartis Ag Organic compounds
GT200500310A (en) * 2004-11-19 2006-06-19 ORGANIC COMPOUNDS
KR101462693B1 (en) * 2006-08-16 2014-11-17 노파르티스 아게 Method for making solid dispersions of highly crystalline therapeutic compounds
FR2918566B1 (en) 2007-07-11 2009-10-09 Pierre Fabre Medicament Sa STABLE PHARMACEUTICAL COMPOSITION OF A WATER SOLUBLE SALT OF VINFLUNINE.
US20090155352A1 (en) * 2007-11-20 2009-06-18 Cephalon, Inc. Microemulsion containing indolocarbazole compound and dosage forms containing the same
EP2229936B1 (en) * 2009-03-09 2015-05-06 PharmaSol GmbH Nanonized testosterone formulations for improved bioavailability
WO2011000811A2 (en) * 2009-06-30 2011-01-06 Novartis Ag Organic compounds
MX2012007229A (en) * 2009-12-22 2012-07-30 Leo Pharma As Cutaneous composition comprising vitamin d analogue and a mixture of solvent and surfactants.
JO3337B1 (en) * 2010-12-13 2019-03-13 Debiopharm Sa Pharmaceutical Compositions Comprising Alisporivir
WO2013042069A1 (en) 2011-09-22 2013-03-28 Ariel-University Research And Development Company, Ltd. Emulsions and methods of making emulsions
KR20190032265A (en) * 2015-12-09 2019-03-27 포스파제닉스 리미티드 Pharmaceutical formulation
CN108601732A (en) 2015-12-09 2018-09-28 磷肌酸有限公司 pharmaceutical preparation
US20190330260A1 (en) 2016-12-21 2019-10-31 Avecho Biotechnology Limited Process
WO2021097256A1 (en) 2019-11-14 2021-05-20 Cohbar, Inc. Cxcr4 antagonist peptides

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Also Published As

Publication number Publication date
PL198330B1 (en) 2008-06-30
DE60042151D1 (en) 2009-06-18
SI1152750T1 (en) 2009-10-31
BRPI0008228B8 (en) 2021-05-25
TWI240636B (en) 2005-10-01
US20140056974A1 (en) 2014-02-27
HK1045807B (en) 2008-12-05
RU2266121C2 (en) 2005-12-20
SK11722001A3 (en) 2001-12-03
BRPI0008228B1 (en) 2016-08-23
HUP0105364A2 (en) 2002-05-29
NO331232B1 (en) 2011-11-07
US8722664B2 (en) 2014-05-13
BR0008228A (en) 2001-10-30
AU765776B2 (en) 2003-10-02
KR20010093281A (en) 2001-10-27
ATE430554T1 (en) 2009-05-15
ECSP083351A (en) 2008-08-29
JP2002537242A (en) 2002-11-05
ES2326783T3 (en) 2009-10-20
NZ513529A (en) 2003-10-31
CA2362277C (en) 2010-03-30
US8575147B2 (en) 2013-11-05
IL144512A0 (en) 2002-05-23
IL144512A (en) 2011-03-31
SK286967B6 (en) 2009-08-06
EP1152750B1 (en) 2009-05-06
MY128362A (en) 2007-01-31
US20020061873A1 (en) 2002-05-23
CZ303979B6 (en) 2013-07-31
EP1152750A1 (en) 2001-11-14
CZ20012931A3 (en) 2001-11-14
HK1045807A1 (en) 2002-12-13
US20080070897A1 (en) 2008-03-20
AU3154200A (en) 2000-09-04
CN100367930C (en) 2008-02-13
NO20013964D0 (en) 2001-08-15
AR022589A1 (en) 2002-09-04
KR100880859B1 (en) 2009-01-30
CA2362277A1 (en) 2000-08-24
CL2009001682A1 (en) 2010-07-23
ZA200106677B (en) 2003-01-14
JP5057610B2 (en) 2012-10-24
JP2012111763A (en) 2012-06-14
WO2000048571A1 (en) 2000-08-24
NO20013964L (en) 2001-10-15
ID30504A (en) 2001-12-13
TR200102385T2 (en) 2002-09-23
IL192666A0 (en) 2009-02-11
CN1339963A (en) 2002-03-13
GB9903547D0 (en) 1999-04-07
AR082579A2 (en) 2012-12-19
KR20080064914A (en) 2008-07-09
HUP0105364A3 (en) 2003-02-28
PL350556A1 (en) 2002-12-16
DK1152750T3 (en) 2009-08-24
PE20001499A1 (en) 2001-01-12

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