PT106310A - CLOTHING PARTS WITH THERAPEUTIC PROPERTIES AND THEIR USE IN THE TREATMENT OF PSORIASIS AND OTHER DISEASES - Google Patents

Abstract

BACKGROUND OF THE INVENTION The present invention relates to dressing articles made in accordance with current methods of fashion design with therapeutical properties comprising soft and anti-allergic textile materials, the fibers of which comprise microcapsules which are coupled to pharmaceutically acceptable compositions of topical action and containing magazines POSITIONED IN SPECIFIC SITES OF THE REFERRED PARTS OF CLOTHING. In this manner, the present invention is useful in the treatment of psoriasis and other diseases insofar as it uses the principles of Chinese traditional medicine, in particular the synergy between acupuncture by magnetotomy and phytotherapy in the commonly usable clothing. The present invention thus has application in the textile, clothing and fashion industry, as well as in the health area, contributing to the improvement of the quality of life of patients subject to the treatment of skin diseases, as well as psoriasis, also functioning as a COORDINATING TO THE TREATMENT OF PATHOLOGIES OF ANOTHER NATURE.

Description

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DESCRIPTION

CLOTHING PARTS WITH THERAPEUTIC PROPERTIES AND THEIR USE IN THE TREATMENT OF PSORIASIS AND OTHER DISEASES

TECHNICAL FIELD OF THE INVENTION The present invention relates to garments having therapeutic properties comprising soft and anti-allergic textile materials which fibers contain microcapsules comprising topically-acting pharmaceutically acceptable compositions and containing magnets positioned at specific locations of said garments. The present invention is intended to have a practical and direct application in promoting health and well-being and can relieve symptoms in the treatment of psoriasis, with 3% of the world population having this affection and also in numerous cases of atopic dermatitis, dry skin or sensitive skin. The present invention also has an intervention in the improvement of diseases of another nature.

SUMMARY OF THE INVENTION The present invention relates to garments having therapeutic properties comprising soft and anti-allergic textile materials which fibers contain microcapsules comprising topically acting, magnet-containing compositions containing magnets positioned at specific locations of said garments. This integration makes possible and makes use of the synergy between techniques used in Traditional Chinese Medicine (TCM) for this and other purposes, namely magnetotherapy acupuncture and phytotherapy in points of the human body 1 2 studied in this field in order to optimize the obtained. The combination of skin / clothing, the search for comfort in the act of dressing through innovations in the textile areas, eg new fibers, research carried out in the field of nanotechnology, practical ways of introducing the therapeutic principles of Chinese medicine in a collection of fashion and, above all, the close relation that clothes establish with the body - the body dressed, are the focal points of analysis through which the advantages of the present invention are evidenced. The present invention satisfies the need to pacify the relationship between the garment and the body. In one embodiment of the present invention, the psoriatic skin is considered a special skin requiring a more careful care, the choice of clothing being fundamental to cover the body harmoniously, providing softness and comfort to the patient. The supply on the market is, however, clearly insufficient. Synthetic fibers are increasingly used for economic reasons, to the detriment of the natural ones, and can cause pruritus and discomfort to the skin of a consumer more demanding and with particular needs. The application of certain decorative elements in clothing, and construction or finishing processes can increase the physical discomfort and sometimes discomfort in clothing. The present invention is also useful in that it will help people with skin diseases and use clothing as a concealer of lesions, to use it for other purposes and to gradually lose the fear of social exposure. The present invention not only materializes through exquisite and excellent textiles of natural origin and concerns in the field of sustainability but also reveals significant concerns in the field of mold design, favoring simple shapes, flowing lines and loose. It is thus useful for anyone who strives to improve the interaction of clothing with the skin, or simply experience the sensation of comfort and convenience by reducing the problems of friction, skin irritation, pruritus, among others resulting from direct contact of the skin with clothing. This invention has an innovative character because it combines the ancient wisdom of Chinese medicine with the innovation and technological development of microcapsules for textile application. Thus, it may also be useful to those wishing to continue a treatment of a disease, since the clothing is thought to be a carrier of substances beneficial to the organism, and in order to provide a physiologically pleasant activity.

Among the advantages of this invention is also an aesthetic concern in the creation of the pieces, their contemporaneity thought according to the trends of Fashion, seasonality and with the possibility of adaptation to the different target audiences. It is worth highlighting the added value that these garments bring when exercising on the user's body beneficial principles, tailored to their personal characteristics. The product is particularly advantageous because it can be used daily and because it makes it possible to enjoy this therapeutic effect simultaneously with the performance of the daily tasks. That is, it does not negatively influence the activities of your user, nor does it restrict them. This invention may be used for the desired time and day-to-day of any individual, regardless of age, sex or professional activity. The continued use of this type of clothing will result in a significant benefit and increase in the quality of life of people, especially when affected by psoriasis or other diseases whose symptoms manifest themselves, among others, cutaneous. The families of these individuals who, in severe cases of the condition, are considerably affected by the patient's emotional instability and physical suffering, financially and psychologically participating in this experience, will also benefit from the present invention. The present invention may also contribute to improving the general population information on psoriasis disease and all diseases which in a similar manner impact on the human figure, including the physical difficulties of these individuals and the strong social component involved in the disease. with a visible disease. This invention may help to minimize the exclusion factor that patients are sometimes targeted for diseases whose symptoms manifest themselves on the skin.

BACKGROUND OF THE INVENTION

CN2151633 discloses a type of multifunctional clothing in the area of health and medical care containing pockets positioned at the stitches of the present invention and the advantages of the present invention in view of the state of the art. of acupuncture of the human body on the side of the part that contacts the body. The interior of the garment may comprise paper bags containing traditional Chinese substances whose components coincide with the acupuncture points, the paper bags are cooked to the fabric and are compartmentalized by the seams. The magnets used are also placed in these paper bags. The present invention, in turn, utilizes the principles of nanotechnology to provide garments which, while utilizing Chinese medicine techniques identical to those disclosed in CN2151633, ie, herbal medicine and acupuncture by magnetotherapy, comprises topically acting phytotherapeutic compositions in uniformly distributed microcapsules along the fibers constituting the textile materials that make up said garments, making them not only more comfortable and innocuous but also more effective in their therapeutic component, since the microcapsules act on the entire surface of skin with which contacting and the location of magnets on garments is prescribed and specifically defined according to the clinical condition to be treated. The substances contained in the microcapsules are gradually released through contact with the skin, thereby ensuring the widening of the patient's physical and emotional well-being while using said garment. The document CN201328367 also proposes to ally the pharmacotherapy to the magnetotherapy, comprising the drug contained in the form of powder, in a bag integrated in an inner garment, concretely in the form of briefs, in contact with the skin and a magnetized block that intends to act at the acupuncture points involved in the treatment of disorders such as inflammation, irregular menstruation, endometriosis, among others located in the pelvic region. The present invention allows not only a more uniform and effective therapeutic action through the use of microcapsules but also due to the strategic and distributed location of the magnets throughout the garments, specific to the disease to be treated. CN101892590 discloses a foam material having functions associated with traditional Chinese medicine which is intended to comprise microcapsules containing various substances and serve the purpose of dyeing and impregnating these substances in the tissues. The present invention discloses a process for producing and integrating microcapsules different from the process described in CN101892590, insofar as said microcapsules are uniformly distributed over the fibers of textile materials carefully selected for this purpose up to an optimum concentration limit value, substances directly into the skin due to mechanical breakage resulting from direct contact with the wearer's skin and combines this therapy with the advantages of magnetotherapy acupuncture.

Similar to the latter document have been found other interesting ones, namely CN1255311 which discloses a tie comprising microcapsules containing chemical compounds to help activate microcirculation and prevent inflammation. 6 7

GENERAL DESCRIPTION OF THE INVENTION The present invention places particular emphasis on the differentiated approach of traditional Chinese medicine against psoriasis and other pathologies, and is another defining element of the target public. There is a growing tendency to seek solutions to health problems within the realm of alternative medicines, especially one which, like this, has no harm or contraindications, and its supporters are increasingly numerous.

In the same way that the skin is the 'coating' of the body, the clothing becomes the skin's coating. Both share the function of protecting the organism against external factors. They play a key role in maintaining body temperature and ensuring blood circulation and comfort. Despite this similarity, a compatible interaction between skin and clothing is not always established. When artifacts or products touch the body, or are touched by it, they become stimuli that promote excitation of the receptors of the skin.

In specific situations of dry, atopic and more severe conditions, such as psoriasis, the skin becomes much more sensitive than normal, and this close relationship can be a source of problems in the area of discomfort and pain caused by pruritus, disturbances in the respiratory capacity of the skin, friction, burning sensation, discomfort, among others. 1. Psoriasis Psoriasis is an inflammatory, non-contagious, hyperproliferative disease of the skin. It was approved in 2010 by Parliament in Assembly of the Republic as a chronic disease. 7 8

This is a disease, according to a quote from Deputy João Oliveira, whose treatment "requires exclusive medications" and which imputs to the patients an average annual cost in the order of three thousand euros. "It is an extremely crippling disease and is the third leading cause of suicide," he stressed (Agência Lusa 2010).

Of unknown etiology, psoriasis (Psr) shows a wide range in severity and in the areas of skin lesion localization. It occurs when certain skin cells, which form the superficial layer called keratinocytes, divide too quickly and begin to accumulate on the surface causing the skin to thicken. Our defenses against bacteria and viruses are based on leukocytes (white blood cells) but in patients with psoriasis some of these defensive cells, once activated, enter into dysfunction and release mediators that in addition to inflammation, increase the speed with which cells skin divide. A cell of this basal layer of the epidermis - which takes about 28 days to reach the cutaneous surface, will do so in psoriasis in about 5-7 days, giving rise to continuous desquamation (Figueiredo 2010) . Psr is a relatively common pathology affecting about 3% of the world population (210,000,000 people) and 250,000 people in Portugal. It has a variable evolution, according to each organism. According to Rebelo (2006), it usually occurs in the young adult, being the age group from 20 to 40 years the most affected, but can manifest itself at any age. Its intensity is variable and it is not possible to predict how it will evolve. 8 9

There are certain factors that aggravate the disease, the main being the stress, the infections and the changes of season of the year. Psoriasis tends to worsen in the winter, not only by minimizing sun exposure, but also due to the friction caused by clothing, and by the occlusion that prevents the skin from breathing normally. Psoriasis is manifested assuming several types, according to the characteristics of the lesions and the affected site. These rebellious desquamative states lie preferentially on the skin of the elbows, knees, scalp and legs, with a tendency to spread a little throughout the body. According to Sousa Basto, Psr is a disease that is not limited to the skin. It can be associated with other diseases, such as cardiovascular diseases and metabolic diseases, such as diabetes.

There is a preconception that this disease can be contracted by contagion, and the reaction of fear or physical aversion to the demonstration of the disease affects the social relationships in the day-to-day and the work of these individuals (Baião 2010). This disease has thus assumed a considerable psychosocial dimension due to the ostracization and social stigmatization to which the individuals who suffer from it are sometimes subject. Many people face serious difficulties in the domain of self-esteem and disruption of the quality of life, being this disease a strong conditioning in the choice of clothing. If on one hand they use clothing as a concealer of the lesions, on the other, the relationship between the skin and the tissues that cover it is not always peaceful, and may even translate into a source of suffering and malaise. Certain textile materials irritate the skin surface, (especially wool and synthetic fibers that cause pruritus; constructive elements of clothing, such as cuts, applications or bulky seams that may bother). The fact that these individuals conceal their bodies with the aid of ordinary clothing prevents the disease from improving because it is less exposed to UV radiation and, on the other hand, the covering of the affected areas potentiates the proliferation of the inflammation, promoting a humid environment, excessively hot, similar to " greenhouse effect " which prevents the skin from breathing naturally and increases the pruritus considerably. 2. Therapeutic clothing

Based on this conflict, it is presented here the possibility of, on the contrary, clothing that is dressed as being an extension of the body and stimulating feelings of well-being, comfort and softness on the skin. In addition to the comfortable side, the present invention presupposes the introduction of a therapeutic component in clothing, supported by the foundations of Chinese medicine, so that the garments developed may consist of a coadjuvant to the treatment of psoriasis and other skin conditions. Possible beneficial effects of clothing resulting from the association of 3 valences: • Suitability of textile materials to these particular needs (choice of materials with high quality and specificity (natural fibers of sustainable production, ecological knitwear: organic cottons, cottons with mixtures silk microfibers, silk and silk (100% natural) silk muslin, MicroModal®, Lyocell Tencell®, which are cellulosic textile fibers produced on the basis of the cellulose of certain woods, such as the beech tree, and which give rise to fabrics of high quality and softness, according to the principles and good practices of sustainable and ecological production, these 3 fibers being very similar, have the same origin but with some differences in the structure; Bamboo viscose and bio-functional textiles, ie, textiles that perform a function and may release a substance on the surface of the user's body, such as SeaCell Pure / Active®, which have anti-inflammatory benefits due to their seaweed and silver extracts), preferably using a pale color palette of colors, cold pastel colors . Preferably, false whites may also be used; old pink; pink baby; kisses; yellow-butter; White; light gray; brown mole.

Suitability of shape and construction of parts, preferably using molds with reduced components, simplified lines, loose and detached silhouette of the body, allowing greater flexibility and freedom of movement, comprising forms with a fluid drop, " liquid " and unstructured, including the elimination of the seam finishes, converting them into fringes and trim with silk ribbon in bias, in order to minimize contact and stimulation of the skin by the elements contained in the clothing.

Application of the fundamentals of Chinese medicine, namely in the context of acupuncture by magnetotherapy implanted in garments and finishing of microcapsules encompassing phytotherapeutic compositions, which act to decrease the severity and extent of skin lesions and attenuate intense itching. 3. Soft Textiles Used 3.1 Natural Fibers Man's ingenuity in developing and processing these raw materials has become more sophisticated over time. Recent decades have witnessed a growing appreciation of natural fibers at affordable prices. Nowadays, the exciting technological developments related to natural, artificial fibers and synthetic enhancements are of immense potential. They can offer exciting new options for an increasingly complex range of consumer demands. The sophisticated developments in man-made fabrics look quite different from the traditional ones that natural textiles used to favor. Combinations of microfibers (a new generation of ultra fine synthetic fabrics), regenerated threads or with silks, cottons and linens provide new shapes and potential performances (Hallett & Johnston 2010). 3.1.1 Silk Silk is such a desirable, seductive and luxuriant fiber that its price sometimes exceeds that of gold. It has a magnificent aesthetic wealth and manages to provide a liquid, sensual and elegant fall. It is considered the most beautiful of all natural fibers. The texture of the fiber is soft and soft, quoting: "texture refers to the surface quality of objects and appeals to our sense of touch" (Seivewright 2007). Depending on how the yarn is woven 12 13 may exhibit both a sculptural structure and a delicate lightness. Its isothermal properties make it cool in summer and warm in winter.

The types of fabric used in the present invention are: a) Silk muslin (transparent, very light, fine, looser structure, gauze type and with an ethereal appearance); b) Silk Satin (fairly soft, has a liquid drop and one side shiny);

These materials were purchased from a traditional merchant. Silk can also appear on the sweater strand in combination with MicroModal® and Tencel®, which according to Hallett and Johnston translates into a light and appealing knit. 3.1.2 Organic cotton Cotton is the most practical, egalitarian and most commonly used of all natural fibers, possessing qualities such as: comfort, absorption capacity, and can also be considered trans-seasonal due to its ease of use in the different seasons of the year. Cotton fiber is, in its natural state, visually appealing with regard to its potential uses for man (cotton balls when picked from the plant suggest the idea of comfort). There is growing concern that cotton-producing countries are moving in a more organic, ecological and sustainable direction in the process. Organic farming methods are based on crop rotation, which helps to restore soil balance, and the use of natural enemies of crop-attacking insects, rather than using pesticides, artificial fertilizers, and other compounds chemicals of persistent toxicity. The chemical compounds used in conventional cotton cultivation weaken their fibers. Organic cotton allows for the production of high-quality garments with softer, smoother and healthier fibers for the skin (Pereira & Rocha 2008). Organic cotton is much more expensive in terms of production, however, it does not pollute the environment and does not present surplus production. 3.2 Cellulosic Fibers of Sustainable Production 3.2.1 Bamboo The use of bamboo is millenarian and is part of the cultural identity of several Asian countries, mainly due to its use as construction material. Nowadays, through technology, perseverance and an imperative need to find organic and sustainable alternatives, one can count on the creation of textile materials as one of the innumerable uses of bamboo. Bamboo has unique characteristics, qualities and benefits, in addition to its contribution to the absorption of greenhouse gases and the fact that it enriches the soil in nutrients. Its fiber is tough and durable. There are some similarities with cotton but it is much softer. Its microstructure allows it to evaporate the perspiration, keeping the user dry and fresh. 14 15

It contains a substance that protects the plant from pests and pathogens, the bamboo kun, which makes the future bamboo fabric naturally antimicrobial and antifungal, drastically reducing the chances of causing skin irritations. This allows it to be grown organically and sustainably, dispenses with the use of pesticides or chemicals and is naturally biodegradable to sun exposure and in contact with the soil. The bamboo fiber is extracted from the stem, so it can be naturally converted into cellulose, or chemically processed into bamboo viscose. The raw material is crushed and reduced to a paste. It undergoes a process called hydro-alkalinization to extract the natural cellulose that contains bamboo kun and is transformed into fiber. Depending on the spinning processes, you can generate a thinner wire than a hair.

Bamboo fabrics are considered to be much softer than cotton ones and have a glossy surface, which glistens slightly and is sometimes compared to silk. It is also relevant to mention the important anti-static characteristics of this textile, which allow it to lean against the skin without being a gatherer or adhere to too much. The woven fabric from bamboo is described as being a fabric with an amazing eco-performance (Hallett & Johnston 2010). 3.2.2 Lyocell Tencel® Lyocell Tencel® is part of the manufactured fibers of cellulose origin. Cellulose is extracted from the main part of the cell wall of plants and especially from the trees. Lyocell Tencel® is considered the first man-made fiber to be environmentally friendly. It is created through sustainable wood plantations and the solvent used for extracting the cellulose can be recycled. Lyocell Tencel® fiber is fully biodegradable. Generates a sturdy fabric with a good drapery and a soft touch (Udale 2008). According to recent dermatological studies on Lyocell Tencel® textile compatibility clothing made of Lyocell Tencel® significantly improves comfort and promotes a sense of well-being. In addition to this, it is chemically free, an important factor for sensitive skin and compared to other cellulosic fibers of natural origin. 3.2.3 MicroModal®

The marketing campaigns of this material advertise that it is the softest fiber in the world. MicroModal® is a cellulosic fiber produced from beechwood. The beech is unbeatable in terms of improving the soil and grows abundantly without the need to resort to artificial irrigation. It is very resistant to pests and environmental damage. Your production process is eco-conscious. Uses little water and soil (cotton requires 10 to 20 times more water). It blends perfectly with other types of fibers. It is naturally soft and pleasant in contact with the skin and has been demonstrating its competence in terms of softness. It exists in the MicroModal® variant, which has a softness factor 4 times greater than cotton. Microfibers are extremely thin fibers (1 denier or less). The thinner the fiber, the softer the textile. MicroModal® is the 2nd finest cellulose fiber in existence. MicroModal® textiles are exceptionally cozy, lightweight and regular in structure. 16 17 3.2.4 Pen Technology

This spinning technology has been developed and optimized by Tearfil with the aim of achieving low pile fabrics, keeping the softness and the touch similar to conventional yarn. The Pen collection consists predominantly of fibers and blends of Modal®, MicroModal®, Bamboo and Viscose®, cellulosic fibers known not only for their silky and shiny characteristics but also for their hairiness.

Through the technology Pen, it was possible to eliminate the typical problems of hairiness of these fibers, without compromising its brightness and silky touch. The softness and

flowability of these materials, as well as the possibility of being evident in the finished articles, has become a great asset for the embodiment of the present invention. From the excellent yarns produced by Tearfil and the access to the textile materials they originated, it was possible to start designing a set of garments suitable for the needs that were refined. The fact that Tearfil had perfected the concept of cellulosic fiber, removing excessive hairiness (which could eventually be the cause of pruritus for more sensitive skins) was a great asset. 3.2.5 SeaCell®

SeaCell® is an innovative fiber with anti-fungal, anti-bacterial and anti-inflammatory properties that combines Lyocell with seaweed. Seaweed is one of the main sources of oxygen in nature and its effectiveness is proven by Chinese medicine as a qualified skin protector (toning the energy of the kidney). They are rich in trace elements, carbohydrates, vitamins, minerals, amino acids, calcium, carotenoids, etc. The SeaCell® structure facilitates the active interaction of substances between the fiber and the skin.

Nutrients such as calcium and vitamin E are released by the body's natural moisture when the fiber is used, thus creating a sense of comfort and well-being.

Additionally, the properties of textiles made with this fiber offer advantages such as breathability, softness and a refreshing feel on the skin surface.

This technological fiber exists in two strands: SeaCell ™ Pure, which offers the effects of algae in its pure state and SeaCell ™ Active, enriched with silver (a powerful antibacterial agent) for added effectiveness. Both the base material of the SeaCell® fiber and the active substances are renewable (Smartfiber AG 2010). 4. Fabric Technology The knowledge of how a fabric behaves in the design and design process is often the result of understanding its composition, structure and construction. While fiber and wire help determine touch perception and how it falls, the overall performance of a fabric depends on how the fiber or wire is used during construction and finishing. Fabrics can be created using a variety of methods, the main ones being weaving and knitting technology. Both require yarn production. In the first one (Figure 1) we assume the interlacing of two sets of wires in a loom. The web (vertical yarns) and the weft (horizontal yarns) and depending on the density, opacity / transparency desired for the fabric, more or less yarns per cm2 are used.

With regard to knitting, the yarns may be less strong than for weaving, allowing a wide variety of yarn types to obtain better textures, which invariably gives rise to a tremendous multiplicity of fabrics. The knitted fabric is constructed through a series of loops interconnected with each other. This allows you greater flexibility, grip and lightness. The construction of the loops and their loops (Figure 2) allows them to achieve a softer texture, easier draping and better adaptation to the body and its movements, than the fabric. The surface of the meshes is generally very pleasant, soft and soft to the touch. Knit technology works every day of the year, and its fabrication is considerably faster than weaving.

The innovations of machinery make knitting a very efficient, and inexpensive process. It is the process that causes less waste. The knitting industry occupies a place of equal importance to that of the weaving industry, even tending to surpass it. This success is not only a fashion product but is mainly due to the characteristics of " fabrics " especially the elasticity, porosity and softness, as well as the technological development of knit looms (Araújo & Castro 1986: 419).

Features: • Comfortable • Practical • Inclusive (dispenses a few button-downs, locks, tweezers etc.) • Versatile • Facilitates body expression • Welcoming • Comfortable • Cozy jerseywear is a range of garments such as t-shirts and poles, which are cut into fabrics which have been industrially knitted, using a process similar to that which is made with fabrics from the weaving, etching. Within this jerseywear type can also include fully knitted pieces using advanced seamless technology (seamless technology) through circular knitting machines that produce the mesh tubularly. This technology is most commonly applied in underwear products. It was decided to develop a collection mainly in mesh, and fabric, to appear, would be only as a complement (in the slopes silk satin and silk muslin).

In this way, it is intended to enhance the already satisfactory characteristics of the mesh to develop exploratory studies of extremely comfortable and soft garments. 20 21

Oeko-Tex The International Oeko-Tex® Association carries out tests on substances harmful to textile products of all types without any health risk. The Oeko-Tex® criteria provide a uniform and scientifically based assessment standard for potential problematic materials in textiles. The Oeko-Tex® label is a sign of the added benefits of proven safety of skin-friendly clothing.

GOTS The Global Standard for Organic Textiles (GOTS) is recognized as the worldwide reference standard for the processing of textiles composed of organic fibers. This label is applicable to organic cotton textile products and provides for criteria applicable to fiber, chemicals, various stages of the textile production process, including packaging and shipping, used accessories, environmental management, quality assurance and social responsibility (CITEVE).

Supima® - The softest cottons in the world

Nonprofit promotional organization of American Pima cotton producers. Licenses to use the Supima® brand (Upper Pima) are only awarded to high-quality textile industries, selected manufacturers and retailers. Usually considered the "cotton cashmere", Supima® is a luxury cotton and surpasses the typical cotton in quality, softness, resistance and shine, in addition to retaining the color better. " A premium quality fiber is required to achieve a luxury product. " (Supima 2009). Supima® cotton is grown organically and sustainably.

Fairtrade - Max Havelaar

It is associated with fair trade. That is, it aims at establishing fair prices, as well as balanced social and environmental standards, in the productive chains. It therefore defines a set of rules that includes economic, environmental and social responsibility issues (CITEVE).

It is concluded that the characteristics of the materials found meet the desired needs and can lead to a collection of solid fashion and well-sustained in its comfort principles, both because the aesthetic characteristics of these materials also collaborate in this sense (brightness, color, fall, opacity) , but as their quality is uncontested, they are environmentally certified, they are pleasant to the touch and offer the requirements of convenience so sought after.

5. INNOVATIONS IN THE TEXTILE SECTOR

It has been found that there are relevant technological discoveries in the investigation of textiles that are neutral to the skin. Clothing produced without the use of harmful substances and chemical dyes, such as certified organic cotton (especially for a specific target group: newborn babies). It is also worth noting the creation of seamless clothing in order to increase comfort and reduce the irritation caused by seams. However, only one antecedent has been found in this area, which devised a therapeutic approach to clothing to skin problems (especially with regard to atopic dermatitis).

It consists of an idea of national origin for the creation of children's undergarments (and also some adult pieces such as undergarments and socks) for the purpose of helping to treat atopic dermatitis. According to Artur Sousa Basto, a dermatologist and technical consultant for the brand, this discovery does not cure, but it attenuates pathology and aims to make the patient's life more bearable. The widely studied and tested SkintoSkin® technology combines cotton and brown algae extracts with silver salts that have important antibacterial properties in the treatment of atopic dermatitis. The products are sold in pharmacies and pharmacies. This company also developed an occlusive fact for the treatment of totally made psoriasis in nylon that is destined to retain the ointments of cutaneous application. However, it does not reveal aesthetic concerns and the material from which it is made (due to its 100% synthetic constitution) can be uncomfortable for psoriasis sufferers. This is similar to waterproof pajamas and was intended to contribute to adherence to topical treatments often prescribed for the treatment of Psr and almost always rejected by patients due to their reluctance to apply cosmetically unpleasant products that stain clothing .

6. THERAPEUTICS 6.1 Conventional Medicine

Although there are some treatments to control the manifestations of psoriasis, they are very expensive; are considered unsatisfactory because they do not meet the 23 24 expectations due to lack of efficacy, slow onset of action; and very commonly involve serious side effects.

The therapies that conventional medicine proposes to control Psr are divided into: a) Local application treatments (cortisone ointments); b) Phototherapy: exposure to UVB (ultraviolet B) radiation / PUVA therapy (psoralen and ultraviolet A) and medication to increase the sensitivity of the skin to light - this therapy has potential adverse effects if consecutive); is used for years c) systemic medication (oral or injectable: acitretin, methotrexate and cyclosporin are prescribed in moderate / severe cases of Psr that do not respond to other treatments - potential serious side effects may occur); d) biological treatments (molecules produced through recombinant biotechnology, presents a solution through a directed action molecule that acts on the specific inflammation without reaching the defenses of the organism, and can result in increased susceptibility to infections). Conventional medicine is unanimous in defining psoriasis as an incurable disease. According to the Director of the Service of Dermatology and Venereology of the Hospitals of the University of Coimbra, Américo Figueiredo " Psoriasis is an incurable disease of the skin ". Brandão (2005) further states that " psoriasis is a chronic, sometimes cutaneous-articular, incurable cutaneous disease ". 24 25 6.2 Chinese medicine The World Health Organization has demanded that traditional Chinese medicine (TCM) be integrated into national health plans. At the close of the National Congress of Traditional Chinese Medicine held in Beijing, the United Nations agency issued a statement urging its integration as "one of the resources to increase and make the service more accessible." The WHO states that "knowledge of traditional medicine, its treatments and practices must be respected, preserved, promoted and transmitted in a manner appropriate to the circumstances of each country", concludes the statement. More than 1,000 representatives from 70 countries participated in the congress of traditional Chinese medicine held in Beijing (Lusa 2008). Chinese medicine has been documented for 3000 years. Not only is it probably the oldest of the medicines, but also the one that has been most practiced throughout the History of Humanity. The archaeological findings of the late Chang dynasty (1000 BC) include acupuncture needles and discussions of medical pathology (Benksy 1996). MTC is a medicine that proposes to analyze the individual through an energetic principle and, with this diagnosis, proceed to treatment through the various disciplines that encompass Chinese medicine.

A disease in TCM is synonymous with energy imbalance, so the solution is to reorganize the energies in order to regulate or harmonize the body properly. By combining Meridian theory with the zang-fu systems (internal organs) and the etiology of TCM, one can explain not only the physiological activities but also the pathological changes that occur in the organism. Meridians and collaterals are channels of energy distributed throughout the body that ensure the conductivity of the body, connecting the internal organs to the various tissues and organs of the body's surface to make it an organic integrity (Beijing TCM School 2003).

There are secular maps showing the exact location of the meridians. It is possible to establish an association between the meridians, the nerves, the acupuncture points and the nerve endings.

The signs and symptoms reflected in the meridians and collaterals can be divided according to location, changes in a meridian, and the number of meridians involved. They can also be divided according to the affected area - where they pass and the organs to which they belong. The signs and symptoms reflected in the meridians and in the collaterals are classified as deficiency, excess, cold and heat (Gongwang 2004). The Chinese people have traditionally been promoting harmony above all in social relationships and with nature. A positive feeling of harmony and well-being is the Chinese ideal of health. To harmonize energy and thus heal it is necessary to harmonize the whole, or it will be treating only part of the problem, causing it to arise again, even if in another form. Chinese medicine tries to treat the origin of the problem, to eradicate it definitively, because this is also the Chinese attitude when facing life: to analyze each small aspect as a result of the whole and essential for the whole (Clínicas Pedro Choy 2011). 26 27

Acupuncture by Magnetotherapy

It was empirically concluded that manipulation of certain body sites would relieve discomforts and / or cure certain diseases. This has been one of the processes that led to the discovery of acupuncture points of action, which have the direct function of harmonizing, regulating, adjusting, benefiting and calming the body (Gongwang 2004). Acupuncture is a medical technique that consists in the placement of filiform needles, currently disposable, at strategic points in order to improve the state of health. When the needle is inserted into the skin and human tissues, it has an effect similar to that of a micro-coil that generates energy, the electrons move from the interior to the surface and when they rise, induce electric current in the spiral. It is thus an induced magnetic field. The insertion of needles in the skin promotes the regulation of the energy circulation, restoring its balance, which causes the body's state of health to be restored. This energy rebalancing can be done with either the needles or through laser stimulation, or even through the use of magnets. Magnetotherapy consists essentially of treating the human being with magnets. The Greek etymology of the word is Magnesium-which means magnet and Therapeia, healing, or care. The phenomenon of magnetism is very vast and refers to an infinity of geomagnetic phenomena, electromagnetic, biomagnetic, bioelectric, etc.

Applied on the skin, the magnet produces electromagnetic waves that penetrate the tissues and act differently depending on whether the area to be treated is positively or negatively charged or has a zero charge. Each region of the body has its voltage: that of the heart for example has the highest positive voltage of the front of the body (Dehin 2000). " The curative effect of the magnets may arise from the faculty of returning the electrical charge of the diseased zone to the normal state " (Bhattacharia and Sierra in Dehin 2000). According to Dehin (2000), at the points of application of the magnets, the various secondary currents that are generated act together and produce photons, that is, energy. The iman favors cellular activity by accelerating the electromagnetic exchanges between the inside and outside of the cells, reconstituting the electrical charge of the cell membrane. Baron in Dehin (2000: 60) proposes that magnets can also stimulate an anti-inflammatory action. The force of the magnet will cause phenomena of vasoconstriction. It is known that inflammation is the reverse process, a phenomenon of vasodilation. " In causing this vasoconstriction reaction, the magnets will allow reducing inflammatory phenomena characterized by an increase in haptoglobin and glycoproteins, specific reactions of inflammation ". Faraday's law, or law of electromagnetic induction, is a law of physics that quantifies electromagnetic induction, which is the effect of the production of electric current in a circuit placed under the effect of a variable magnetic field or a circuit in motion in a magnetic field constant.

According to Faraday's law of induction, the electric current induced in a closed circuit by a magnetic field is proportional to the number of lines of the flux that crosses the area involved in the circuit in the unit of time (Silva 2009). The mechanism of acupuncture needles is comparable to that of a dynamo since a direct current is generated by converting mechanical energy to electrical energy through electromagnetic induction. The dynamos consist of a magnet and a coil. The mechanical energy rotates an axis in which the magnet is located, alternating the north and south poles in the coil and by induction generate an electric energy. The opposite, ie the coil on the shaft, is also possible (Silva 200 9).

It is assumed that there is a direct effect of the magnetic fields on all parts of the body that are exposed to it. The magnets modify the electromagnetic balance of the relative zones and also of the surrounding areas. The acupuncture effect of magnetotherapy has a considerable advantage over needles because of the impossibility of walking with permanently applied needles (with the exception of semipermanent needles used in acupuncture or ASPs). The magnets allow a longer action on the acupuncture points that are considered by Dehin (2000), " privileged bioelectric places of the body ". Unlike the needles, the magnets allow a more nuanced action, so they do not require a pinning as precise as the needles because their magnetic irradiation affects a wider area.

It is concluded that the application of magnets at strategic clothing sites (Figures 6A, 6B and 6C), corresponding to the acupuncture points responsible for collaborating in the treatment of Psr, would be the ideal way to be able to stimulate the improvement of the disease through clothing, for a continuous period corresponding to the period of use of the garment.

The points used in acupuncture are classified into 5 movements: wood; fire; Earth; metal and water. These notions are mere metaphors intended only to establish the applicable comparative terms.

Phytotherapy Phytotherapy consists of a set of Chinese herbal formulas and their preparation to combat a multitude of diseases. It is an essential component in the treatment through Chinese medicine. It makes use of the physiological and therapeutic properties of thousands of plants (around 8.750) as well as of herbal compositions through formulas optimized over time, some of which are for secular use and others result from more recent research. The use of Western medicine drugs through phytotherapy is perfectly acceptable, provided that said drugs consist of beneficial medicinal plants, of 100% natural origin and without any contraindication or side effect. The phytotherapy allows to complement the treatment programmed in the consultation of Chinese medicine, optimizing the obtained results. It ends up being the least visible side of TCM, but it has a decisive value for the success of treatment, as or more important than that of acupuncture (Clínicas Pedro Choy 2011).

Psr Treatment by MTC

According to traditional Chinese medicine (TCM) psoriasis can have a cure. The complexity of psoriasis, and the way it affects people's lives, would justify their approach being broader and that therapies instituted in the West always take into account that in addition to the disease called psoriasis there is a person in suffering, almost always hidden. Whoever deals with people with this condition knows well, not only the disease they carry on the skin, but also the disease they carry "under the skin". (Choy, J 2010).

As pointed out by Pedro Choy (2011), Chinese medicine treats Psr as an energy problem and, in the face of this diagnosis, adopts a therapy that involves restoring balance and energy, using age-old techniques whose effectiveness has already been demonstrated in the treatment and improvement of diseases.

Regardless of the approach taken, it is essential that the skin breathe and is in contact with air and sunlight, the latter being one of the key aspects to treat psoriasis through ultraviolet radiation.

In Chinese medicine Psr is considered to be a disease that manifests itself in the skin but which originates from an abnormality in the functioning of the liver and spleen, resulting in the release of what in TCM is called " liver fire ". In other words, what is observed in the psoriatic skin is a manifestation on the surface of the skin of the excess heat generated in the body. This disease effectively has a metabolic origin, since the liver fails to fulfill its normal functions and promotes a kind of global blood intoxication. What is observed in the skin of the psoriatic is thus translated into the product of its internal toxicity. 31 32

Therefore, TCM is intended to address the cause of heat and toxicity manifested through the skin; treating the liver (considered as the origin of the disease) and the organs associated with it; balance the spleen (which in a way protects the liver and increases "earth-like energy" to compensate for the heat that the liver releases); (because it is through the blood that the disease spreads, in the form of heat, to reach the skin) a circumstance in which one must also treat the skin and finally address the emotional state of the patient.

When the emotional state goes through stress, self-segregation, depression, among others, it is considered that can seriously aggravate the symptomatology of this disease. In the face of serious problems or major setbacks, the disease manifests itself with more intensity. It is thus important to foster the tranquility and harmony of the mind.

In the specific case of psoriasis, Chinese medicine eliminates the symptoms of psoriasis in 30% to 40% of the cases, and in the remaining majority there are visible improvements (Choy, P 2011). Currently, MTC and conventional medicine are unanimous in characterizing psoriasis as an autoimmune disease that arises when the immune response is triggered against the individual's own cells and tissues. Thus, the physiological and magnetic balance of the body's defenses plays a decisive role in improving the disease.

Pedro Choy underlines that Chinese medicine therapy for Psr is based on the use of phytotherapy and acupuncture for a long period of two to three years and reports that heat, sun exposure and salt water are extremely beneficial and determinants of treatment success. 6.3 METHODOLOGIES OF THE INVENTION Chinese medicine was the tool chosen for the extremely positive results obtained in the treatment of skin diseases, presenting a remarkable supremacy over conventional medicine and other alternative medicines, due in particular to the following characteristics: a) non- invasive, using therapies of action external to the body; b) uses substances and compositions of natural origin; c) millennial active and technical principles, with proven effectiveness; d) philosophical principle of facing the organism as a whole; e) seeks to identify and treat the origin of the problem and not only its manifestation in the form of symptoms; f) seeks the complete and, where possible, definitive eradication of the cause of the problem; g) seeks to contribute to the physiological balance of the human body. The object of the present invention is to include everyday clothing in the process of therapy and / or cure of a disease, in particular in the psoriasis therapy process. Here therapeutic clothing is proposed using a practical and interventionist methodology, compatible with the methodologies used in fashion design. The present invention involved a prior analysis and cross-referencing of information in various areas of knowledge such as dermatology, Chinese medicine, psychology, sociology, ergonomics, modeling of clothing directly on the manikin in order to perceive draping, bio-functional textiles and R & D of new products.

With regard to the aesthetic aspect of the project that was the origin of this invention, it was intended to illustrate and follow up this theoretical search by the physical / mental harmony. Since the motto transversal to this work tries to fill the problematic resulting from the role played by the skin as interface between the body and the clothing, the function assumes as the concept and base of differentiation with respect to the available solutions that constitute the state of the of the present invention.

Microcapsules in the Textile Industry The textile industry has reacted slowly to the numerous possibilities that microcapsules have to offer. Nowadays, the number of commercial applications in the textile industry has been increasing, especially in the textile industries of Western Europe, Japan and North America. These textiles with new properties and added value (technical textiles and medical textiles), encourage industry to use microcapsule creation processes as a means of providing finishes and innovative properties to textile materials - for example - controlled drug release (Cardoso 2006: 26).

In Portugal there are already some factories that apply patented microcapsules to the textiles and commercialize these products, mainly for export. However, only 34 35 did we find a national company that produced the microcapsules in the field of Research and Development of new products, Devan-Micropólis. Devan-Micropólis emerged as a spin-off from the University of Minho, where it initiated a microcapsule research program at the Department of Textile Engineering in 1996 and developed studies mainly in the field of Phase Change Materials. The company was formed in 2001 and currently belongs to the Belgian group Devan Chemicals. Devan Portugal is headquartered in the Science and Technology Park in Maia and is dedicated to the R & D of new products / uses for microcapsules and the commercialization of products already developed (see, eg, PT 102796, PT 103265 and PT 103576).

When firmly anchored in a fabric / mesh structure or coating, microcapsules can introduce new intelligent functionalities into the textiles where they are contained without affecting the appearance or texture of those fabrics (Ghosh 2006: 221).

As far as microcapsules are concerned, the only disadvantages encountered may be related to the relatively high costs of producing and maintaining garments. The technology optimized by Devan implies that microcapsules must withstand more than 30 conventional washing and drying cycles (Gohsh 2006).

In any case, handwashing of garments subjected to this type of finish is recommended to produce the least possible friction and prevent the microcapsules from breaking down and spreading the contents. This maintenance prudence aims to minimize the loss of the active substance, maximizing its effect on the skin when garments are worn.

Concept and Design The progressive evolution of the 8 prototype coordinates - or the combination of pieces from the collection was directly associated with the concept of resolution / improvement of a cutaneous manifestation disease, in which in a possible embodiment of the present invention, said disease is the psoriasis. It is intended to represent an aesthetic progression in each coordinate, in the sense of the imbalance for the balance; from confused to simplified and from asymmetry to symmetry.

Through various exploratory exercises modeling clothing directly on the manikin in order to perceive the draping of the fabrics, the knit was worked directly on the mannequin in curious volumes and caught, following the maxim: Design from the fabric. The possibility of creating a new texture with the fabric itself was thus determined, thus creating a new fabric. Also included in this concept is the use of transparent tissue (silk imparted in an odd way) to minimize the appearance of psoriatic lesions and consequently attenuate the stress associated with concealment of the body, or only a few particular areas, impairing the respiration of the skin and causing the patient to be ill. Transparent fabrics have the advantage of letting in air and light. The therapeutic clothing described above has enormous potential for industrialization in the textile sector and with numerous applications in the area of physical and mental health. 36 37

Market The target audience of this collection corresponds to a sector of the special population in the field of skin diseases. In this way, the design process was the object of great consideration, considering from the beginning of the process all the aspects that would reflect and physically impact the body. It is important to consider that this body that one intends to wear is a "wounded" body. It is vital to address a variety of factors and to consider the care needed to defend the skin that lies beneath the garments which are the subject of the present invention. This is a sensitive, fragile and damaged skin. It has been chosen to direct the present invention to a female audience because of the creative freedom that the womenswear category enables, but therapeutic apparel is not excluded from the scope of the present invention based on the principles and technologies herein publicized, aimed at the children and the male audience. However, more important than defining factors such as age, gender, size, social status, purchasing power, or values of the target audience, it is necessary to address what has been considered the most basic and elementary of their needs - to pacify the relationship of skin with clothing and provide quality of life to those who use it.

The actual persons to whom the present invention is directed deal in their day-to-day with prejudice, defeat, pruritus, displeasure of being enveloped in diseased skin 37 38 and giving them a " label " attributed by the company where they are inserted. Psoriasis is a relatively frequent disease, affecting about 3% of the world population (210,000,000 people) and 250,000 people in Portugal. Conventional medicine considers it incurable. It usually arises in the young adult, being the age group of the 20 to 40 years most covered, but can manifest itself at any age. Its intensity and evolution vary. It is not possible to predict how it will evolve. The present invention is intended to have a practical and direct application in health promotion, having a very specific and numerous target audience (3% of the world population has psoriasis and a much higher percentage suffer from atopy or very sensitive skins).

In summary, the present invention satisfies the need to pacify the relationship between the garment and the body. Considering a special skin that requires more careful care, it is important that the garment is chosen so as to cover the body harmoniously, with softness and comfort and the market offer is manifestly insufficient. Synthetic fibers are increasingly used for economic reasons, to the detriment of the natural ones, and can cause pruritus and discomfort to the skin of a consumer more demanding and with particular needs. The present invention not only materializes through exquisite and excellent textiles of natural origin and concerns in the field of sustainability, but also reveal important concerns in the field of mold design in simple, fluid and loose lines.

In addition to being designed to provide comfort, the articles disclosed herein enable clothing to be coadjuvant to the treatment of skin diseases, wherein in one embodiment of the present invention said disease is psoriasis. This project addressed clothing as a vehicle for beneficial substances, which, when absorbed / stimulated through the skin, can improve the general health of the individual. The marketing of these items of clothing will play a fundamental therapeutic and social role in the life of psoriatics, helping them, on the one hand, to gradually lose their fear of social exposure and on the other to feel more comfortable in their daily lives while simultaneously being treated by the topical substances contained in the microcapsules and being released on the skin throughout the period of use of said garments. It may also contribute to improving the population's information about the disease and all its conditions. The required interaction between body and skin has been optimized and the need to find comfort in heavily clogged clothing. The garments designed are equipped with advanced finishing technology (microcapsules) and with the embryonic use of magnets in clothing to stimulate specific areas of the body and promote balance and health. 39 40

In other embodiments of the present invention and depending on the location of the points at which the magnets act and the herbal formulas which are inserted into the microcapsules, we can obtain good results in the process of treating various other diseases. Chinese medicine has as its scope the totality of diseases that can arise throughout the various stages of life: childhood, adolescence, adulthood and old age. There is no exhaustive list of pathologies that Chinese Medicine deals with.

Among others, therapeutics are developed for the following affections: Pathologies that cause pain, where we can include back pain (neck pain, back pain, back pain, sacralgia), joint pain (arthralgia), muscle pain, rheumatic pain , pain resulting from tendonitis, migraines, postoperative pain, among other types of pain. Psychological problems also represent an important part of consultations and treatments: depression, stress, anxiety, psychological exhaustion, anorexia, insomnia, psychoses, phobias, among other disorders. As well as pathologies associated with neurological diseases, diabetes, asthma, repetitive infections, stroke sequelae, menstrual problems, fibromiomas, infertility, growth and / or developmental delays. These techniques are also sought to respond to rare, unknown or unidentified diseases. And also in other intervention areas such as: Weight loss, Diabetes or symptoms of deprivation resulting from smoking cessation. 40 41 Chinese Medicine deals with and acts on various diseases and clinical conditions, whereby the present invention can be used to treat or provide therapeutic continuity to any of them, by simply adjusting the points and phytotherapy to the diagnosis done for each individual . There are approximately 8,750 different plants for phytotherapeutic use that can be microencapsulated, as well as thousands of different combinations of possible points of manipulation with magnets, depending on the goals defined in the therapy. The technological complexity of the piece may vary depending on the prescription or validation of the treatment. The therapeutic clothing described above has enormous potential for industrialization in the textile and clothing sector for commercialization in the fashion industry and has numerous applications in the area of physical and mental health, improving the quality of life and well-being of patients.

DESCRIPTION OF THE FIGURES

Figure 1 - Structure of a fabric (weft and web).

Figure 2 - Structure of a mesh (loop point).

Figure 3 - Map of the location of the acupuncture points used in the treatment of psoriasis:

Large Intestine Meridian (LI) 11 and 16; Meridian of the Heart (C) 7; Lung Meridian (LU) 7; Bladder Meridian (BL) 12; Gallbladder Meridian (GB) 31; Meridian of Spleen (SP) 6 and 10; Liver meridian 41 42 (F) 8; Stomach Meridian (E) 36; Meridian Ran (VC) 17, 12, 4 and 8; Meridian Du (VG) 4, 14, 16 and 20.

Figure 4 - Microcapsule representation. 1. Nucleus; 2. Coating wall.

Figure 5A: Scanning Electron Microscope (SEM) image of microcapsules obtained (augmented 3.0K); Figure 5B: SEM image of the integration of the microcapsules into the fibers of the tissues used (increased 1.5K).

Figures 6A, 6B, 6C - Technical drawing of garments produced in prototype (made of fabric) with the location of the magnets represented in the form of dots.

DETAILED DESCRIPTION OF THE INVENTION

In order to ally the benefits of acupuncture to those of herbal medicine, the possibility was made to effect a microcapsule finish on the textile materials to be used in the manufacture of therapeutic garments of the present invention. The aim was to achieve controlled and gradual release in the tissue and consequently in the skin of some of the active substances present in the medicinal plants preferably used in the treatment of psoriasis.

The microencapsulated substances in one embodiment of the present invention, intended for psoriasis treatment were: Fructus Cniidi; Lu hui; mint, to intervene in combat and immediate relief from pruritus, adding to a refreshing sensation to the skin surface. • Fructus Psoraleae, used in the composition of an ointment prescribed for the treatment of Psr - Huang Lian Su Gao symptoms, whose action reduces pruritus, redness and lesion size, preventing its reappearance.

Ghosh (2006: 221) defines microcapsules (Fig. 4) as spherical or irregular particles with a solid wall surrounding them and harboring the active substance within them. Its diameter usually varies between 1 - 1000 pm. In applications for the textile industry the preferred diameter of the microcapsules is between 1-60 pm (Cardoso 2006). Aloe vera is considered a powerful regenerating agent with anti-inflammatory and natural antioxidant effects. It also has antibacterial, healing characteristics, ability to rehydrate dermal tissue damaged by burns or other injuries. It also has a characteristic that is especially important for dry skin - it helps promote skin flexibility. It quickly minimizes the pain sensation. The fact that it is extremely moisturizing causes it to repair damaged skin tissue. The technology used in the microencapsulation of "water-in-oil" compositions, such as the topical herbal remedies employed in the present invention, has been developed based on US 7803422 and US2010304023. 43 44

The microencapsulation process involves wrapping small particles or droplets of a composition, the core, with a wall / layer composed of a solid material, generally a polymer, for the purpose of permanently or temporarily protecting said composition which contains the active ingredient (s) of interest from the external environment.

In the present invention, the ingredients contained in the microcapsules can be released into the tissues by mechanical rupture of the microcapsule wall (consumer friction in the use of the garment); by solubilization or melting of the wall or diffusion of the core through the same wall.

In the case of the microcapsules of " category " skincare used here, its effect is effective on a daily basis, it being possible to re-apply the said microcapsules to the garments, generally after 30 washes, at which time the contents of the microcapsules.

There are different ways to microencapsulate a compound. The most used methods are divided into chemical, physico-chemical or mechanical processes. Chemical processes consist of polymerization and polycondensation processes in which the wall of the microcapsule is formed in situ by already formed polymers or even being precondensed from resins, these processes being generally based on dispersion technologies and include polymerization by suspension , emulsion, precipitation and dispersion, and interfacial polycondensation by suspension, emulsion and precipitation (Cardoso 2006: 25). Emulsion and dispersion polymerization and dispersion polycondensation lead to the gradual precipitation of the polymer which produces the final wall on the surface of each particle or droplet individually, or by coagulation to form the matrix of the microcapsule.

Typical examples, not limiting in the scope of the present invention, are the microencapsulation of compounds resulting from the emulsion polymerization of oils in water, wherein the solvent is aqueous based, or water-in-oil polymerization (Cardoso 2006: 25).

A disclosed procedure is to effect the polymerization of oils in aqueous basis, which process is more feasible to be used on an industrial scale. This procedure consists in dispersing the oil to microencapsular in water and forming a stable emulsion. Thereafter, the polymeric wall forming monomers of the microcapsule are added to the emulsion and, by controlling the time and speed of agitation, the microcapsules are formed.

The pieces have been subjected to a quality test and have soft touch characteristics and a pleasant soft aroma. 45 46

Microencapsulated phytotherapeutic compositions

In one embodiment of the present invention the microencapsular plant extract Fructus Psoraleae, which does not exist in the Portuguese Pharmacopoeia, is an aqueous extract of the plant Psoralea Coryfolia L., a legume (Fabaceae). Most of the preparations available from this plant (aqueous extracts) are of Chinese origin and are made up of 98% of psoralen (CnH603) a molecule of the coumarins and phenols family.

In another embodiment of the present invention the microencapsular plant extract is that of Fructus Cniidi whose chemical characteristics are similar to those of Fructus Psoraleae.

Both compounds have a hydrophilic nature, implying that they can be solubilized in water and in some solvents of greater polarity, being insoluble in hydrophobic substances like oils or fats.

Since the microencapsulation process required the use of water-insoluble compounds, it was attempted to alter the characteristics of the compound, with the hypothesis of removing all water by evaporation. However, even if this hypothesis could be carried out, the molecule would not be solubilized in any compound with hydrophobic characteristics.

A process called silylation was also tested, which consists of a modification of the molecule, making it more volatile and able to be analyzed as an essence by gas chromatography, but it was assumed that in the silylated form it would lose its activity because its radicals would be modified (Pintão 2011). 46 47

Thus, the formulas that were used in the microencapsulation assays contained 0.5 liters of Fructus Psoraleae and 0.5 liters of Fructus Cniidi. The microencapsulation process of these compounds proved to be ineffective according to protocol methods for polymerization of oils in water, since the formulas were dissolved, so their yield was practically nil. This failure can be justified on the grounds that the formulations required to microencapsulate are hydrophilic and non-hydrophobic (as would be ideal for microencapsular) for the following reason: Chinese herbal formulas are mostly drinkable, are considered to be dietary supplements and are sometimes marketed in the form of capsules, but are usually present in flasks with built-in droppers. An average of 50 drops per dose is then diluted into a half-filled glass of water to facilitate ingestion, usually bi-daily. Formulas are prescribed according to symptomatology and in combination with other natural formulas and medicines. They are composed of extracts of medicinal plants (phytoactive concentrate extract approximately 30%, 1% glycerin and 0.5% alcohol).

The microencapsulation methodologies of water-in-oil type phytotherapeutic compositions disclosed in US 7803422 and US2010304023 were taken as reference to optimize and stabilize the above-described embodiments relating to extracts based on Fructus Psoraleae and Fructus Cniidi.

In another embodiment, it has been chosen to apply Lu Hui, a plant used in the treatment of 47 48 skin by MTC, commonly known as Aloe Barbadensis, or Aloe Vera whose extract can be solubilized in light mineral oils. Since fat-soluble substances are able to cross the superficial mantle of the skin and are absorbed until they reach the deeper layers and pass into the bloodstream, this principle can be harnessed for the administration of various medicines (Medipédia 2008).

As for Lu Hui, it is considered a powerful regenerator with anti-inflammatory and natural antioxidant effects. An aloe leaf has more than 75 nutrients and 200 active compounds, including 20 minerals, 18 amino acids and 12 vitamins in their chemical makeup, allowing for easy absorption into the skin. It has antibacterial, healing characteristics, ability to rehydrate dermal tissue damaged by burns or other injuries. It also has a feature that is especially important for dry skin - it helps promote skin flexibility. It quickly minimizes the pain sensation by its calming and refreshing effect. The fact that it is extremely moisturizing causes it to repair damaged skin tissue.

Application of magnets on garments

In addition to the above characteristics, small magnets were applied to the designed garments at positions corresponding to the acupuncture points responsible for improving the condition of psoriasis. The magnets allow a more prolonged and effective action on the acupuncture points that are considered privileged bioelectric sites of the body. The curative effect of the magnets may result from the ability to return the normal electrical charge of the zone affected by the disease in question to the normal state.

The 18 points that can be stimulated via magnets to produce improvements in the psoriasis condition are shown in Figure 3 and are described below.

In the twelve Regular Meridians: 11 (Qu Chi) and 16 (Ju Gu) of the Large Intestine Meridian are two points that release excess heat from the body in general and from the skin. They are often used in inflammatory diseases and in fever, precisely because they release the heat; 7 of the Heart Meridian (Shen Men) which literally means "doors of the mind" is used with double effect. On the one hand it is a point that releases the excess heat in the meridian of the heart (the meridian of the heart goes through the entire arm) and on the other hand it is highly tranquilizing; 7 of the Lung Meridian (Lie That) releases excess energy from the lung organ and balances the lung meridian. MTC argues that there is a connection between the lung and the large intestine and this point bridges the two meridians that decisively influence the skin and are chosen to treat any type of skin disease; 31 of the Gallbladder Meridian (Feng Shi) comes in association with the liver meridian (point 8), are two points that disperse the excess energy between the liver and gallbladder, eliminating fire and strengthening water. The liver releases the extra energy from the fire, through the gall bladder and thence through the skin, and its meridians (which cross the legs and go to the skull). Through these two releases the excess fire. Point 31 allows to disperse the excess energy of the fire type existing in these two meridians; 8 of Liver Meridian (Qu Quan) is the point corresponding to water energy. Water has an effect contrary to the effect of fire, inhibiting it. The excess heat is then controlled; 6 (San Yin Jiao) and 10 (Xue Hai) Spleen Meridian have toning effects of the spleen. The spleen corresponds to the energy of the center and to the movement earth. When promoting soil, it is possible to counteract excess heat. The spleen is Yin. Point 6 (San Yin Jiao) translated literally means junction of the three Yin organs which results in a large increase of yin (cold) energy to compensate for the excess energy that exists in the Yang (heat) type. The spleen 10 fulfills the same functions as in point 6, but has an additional feature. It is a point that rules the blood, Xue Hai, which translated means sea of blood. Blood is responsible for spreading heat and disease through the body and into the skin; 36 Stomach Meridian (Zu San Li) is a great energy s tonic of the spleen, stomach and kidney. It is only possible to counteract the excess fire (Yang energy) by increasing the energy of the Yin type and the spleen / stomach are connected in the same way as the liver and the gallbladder. While these correspond to the movement of fire, the former belong to the movement of the earth. The 36 of the stomach, in addition to toning the earth also tones the energy of the kidney (main symbol of the water movement), earth and water are the main antagonists of fire. This point increases the ability of the digestive tract to acquire matter in a balanced way and to facilitate the metabolism. Thus, it helps the body to detoxify, it helps the blood to be 'purified' in order to facilitate the elimination of toxins. 12 of the Bladder Meridian (Feng Men), increases the anti-wind / heat effect of the liver by synergizing this same effect also predicted by the action of the aforementioned, point 31 of the gallbladder (Feng Shi - market of the Wind ) and onwards 16 of the Du Mai (wind palace) "in Chinese medicine the wind carries the heat, controlling the wind allows to appease the heat" (Choy 2011).

In the eight extra meridians:

Ren Mai (Meridian Vaso da Conceição): Point 17 (Shan Zhong, upper heater - has direct effect on lung and liver), 12 (Zhong Wen, medium heater - effect on the spleen), 4 (Guan Yuan , lower heater -rim such as 4 Meridian Du), are midline points that balance the metabolism. What these three points used together are special is that they make a team that acts in a body that the Chinese call San Jiao (translated means triple heater). The 8 (Shen Que) is a point that stimulates the body's defensive energy and promotes a balance of defenses in its overall. The balance of immunity plays a key role in the regulation of psoriasis. 51 52

Du Mai (Meridian Vaso Governador): 0 point 4 (Ming Men), which is a great energy tonic of the kidney, increases water (apply the same assumptions of the stomach 36); 14 (Da Zui), 16 (Feng Fu) and 20 (Bai Hui) are extremely well-recognized points for releasing excess heat (they have the same justification as points 11 and 16 of the large intestine). 20 is a highly tranquilizing point that is used to treat any kind of psychological pathology (Choy 2011).

The points to be used in an embodiment of the present invention (Figure 3) were studied and prescribed by Dr. Pedro Choy, Vice President of the World Federation of Chinese Medicine Societies (WFCMS) and President of ΆΡΡΑ ( Portuguese Association of Acupuncture Professionals).

EXAMPLES The example described below should not be construed as limiting the scope of the present invention as it pertains to one of its possible embodiments.

Example 1

Clothing comprising aloe vera capsules The microcapsules were successfully incorporated into the mesh of the garments made. The samples have the same unique softness characteristics and a pleasant soft aroma.

The meshes were treated with Devan's eSCENTial ™ Aloe Vera product and subjected to a quality test. A Scanning Electron Microscope (SEM-52

Scanning Electron Microscope) through which it was possible to identify the presence of well coupled and uniformly distributed microcapsules along the textile fibers (Fig. 5A and 5B). It was further verified that the Aloe Vera microcapsules were not damaged or broken during the application process (by depletion - 3g / m2).

Three prototypical coordinates were constructed with therapeutic effects. The prototypes were constructed comprising privileged materials: natural fibers very soft, thin and without hairiness; the shapes of the pieces are loose and loose respecting the shapes and freedom of movement of the body, as well as its possible limitations.

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Claims (6)

Garments having therapeutic properties characterized in that they comprise mild and anti-allergic textile materials whose fibers comprise microcapsules comprising pharmaceutically acceptable topical action phytotherapeutic compositions and magnets positioned at specific locations of said garments corresponding to the acupuncture points in the body human. Garments according to claim 1, characterized in that the microcapsules contain pharmaceutically acceptable phytotherapeutic compositions, such as extracts based on Fructus Psoraleae, Fructus Cniidi, Aloe Barbadensis, seaweed and silver extracts, seaweed extracts and silver and extracts of medicinal plants. Garments according to claims 1 and 2 characterized in that they are preferably made with soft and anti-allergic textile materials such as (i) natural fibers of sustainable production; (i) eco-design fabrics with reduced environmental impact, namely organic cottons, cottons with silk blends and microfibers; (iii) 100% natural satin silk and silk muslin; (iv) textile fibers of cellulose origin, produced on the basis of the cellulose of certain wood, such as beech, similar in composition, of the same origin but whose structure is variable; viscose of Bamboo and textiles with a therapeutic performance and function, being able to release an active substance on the surface of the user's body. Garments according to the preceding claims, characterized in that they contain on their surface magnets distributed and located at one or more of the acupuncture points designated as the Large Intestine Meridian (LI) 11 and 16; Meridian of the Heart (C) 7; Lung Meridian (LU) 7; Bladder Meridian (BL) 12; Bile Vesicle Meridian (GB) 31; Meridian of Spleen (SP) 6 and 10; Liver meridian (F) 8; Stomach Meridian (E) 36; Meridian Ran (VC) 17, 12, 4 and 8; and Meridian Du (VG) 4, 14, 16 and 20. Garment containing magnetos and microcapsules of plant protection compositions as claimed in claims 1 to 4 for use in medical treatment, characterized in that they are used in the treatment of psoriasis. Garments containing magnetos and microcapsules of plant protection / medical treatment compositions according to claim 5, characterized in that they are used in the treatment of other diseases and clinical conditions, such as dermatological diseases; back pains such as neck pain, back pain, low back pain, sacralgia; joint pain such as arthralgia; muscle pain, rheumatic pain, pain resulting from tendonitis; migraines; postoperative pain; diseases and psychological conditions such as depression, stress, anxiety, psychological exhaustion, anorexia, insomnia, psychoses and phobias; pathologies associated with neurological diseases; diabetes; asthma; recurrent infections; stroke sequelae; menstrual disorders, fibromiomas, infertility; delays in growth and / or development; weight loss, diabetes and withdrawal symptoms resulting from smoking cessation. Lisbon, November 7, 2012 3