PT105073A - Processo de obtenção de extractos peptídicos bioactivos através da hidrólise de proteínas de soro de leite com enzimas de cynara cardunculus, referidos extractos e respectivas utilizações - Google Patents

Processo de obtenção de extractos peptídicos bioactivos através da hidrólise de proteínas de soro de leite com enzimas de cynara cardunculus, referidos extractos e respectivas utilizações Download PDF

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Publication number
PT105073A
PT105073A PT105073A PT10507310A PT105073A PT 105073 A PT105073 A PT 105073A PT 105073 A PT105073 A PT 105073A PT 10507310 A PT10507310 A PT 10507310A PT 105073 A PT105073 A PT 105073A
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PT
Portugal
Prior art keywords
extracts
hydrolysis
peptides
enzymes
proteins
Prior art date
Application number
PT105073A
Other languages
English (en)
Inventor
Francisco Xavier Delgado Domingos Antunes Malcata
Maria Manuela Estevez Pintado
Tania Sofia Granja Tavares
Maria Manuela Faria Amorim
Rui Manuel Matos Meireles De Barros
Joao Ernesto De Carvalho
Carlos Jose Dias Pereira
Marta Helena Fernandes Henriques
Isidra Sanchez Recio
Mercedes Gonzalez Ramos
Original Assignee
Consejo Superior Investigacion
Univ Catolica Portuguesa Ucp
Escola Superior Agraria De Coimbra
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Consejo Superior Investigacion, Univ Catolica Portuguesa Ucp, Escola Superior Agraria De Coimbra filed Critical Consejo Superior Investigacion
Priority to PT105073A priority Critical patent/PT105073A/pt
Priority to PCT/IB2011/051811 priority patent/WO2011135513A1/pt
Publication of PT105073A publication Critical patent/PT105073A/pt

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    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
    • A23C21/00—Whey; Whey preparations
    • A23C21/02—Whey; Whey preparations containing, or treated with, microorganisms or enzymes
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
    • A23J3/00—Working-up of proteins for foodstuffs
    • A23J3/30—Working-up of proteins for foodstuffs by hydrolysis
    • A23J3/32—Working-up of proteins for foodstuffs by hydrolysis using chemical agents
    • A23J3/34—Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes
    • A23J3/341—Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes of animal proteins
    • A23J3/343—Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes of animal proteins of dairy proteins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A23L33/18—Peptides; Protein hydrolysates
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A23L33/19—Dairy proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/20—Milk; Whey; Colostrum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/01—Hydrolysed proteins; Derivatives thereof
    • A61K38/012—Hydrolysed proteins; Derivatives thereof from animals
    • A61K38/018—Hydrolysed proteins; Derivatives thereof from animals from milk
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • General Health & Medical Sciences (AREA)
  • Nutrition Science (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Developmental Biology & Embryology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

A PRESENTE INVENÇÃO REFERE-SE A UM PROCESSO DE OBTENÇÃO DE EXTRACTOS PEPTÍDICOS DE PROTEÍNAS DO SORO DO LEITE, POR HIDRÓLISE DE UMA OU MAIS PROTEÍNAS OU PÉPTIDOS QUE CONTÊM AS SEQUÊNCIAS DE AMINOÁCIDOS DE PÉPTIDOS BIOACTIVOS, UTILIZANDO, PARA ESSE EFEITO, ENZIMAS PROTEOLÍTICAS, EM PARTICULAR CARDOSINAS E OUTRAS ENZIMAS SIMILARES PRODUZIDAS POR ESPÉCIES DE CYNARA. ALTERNATIVAMENTE, OS PÉPTIDOS PODEM OBTER-SE POR SÍNTESE QUÍMICA OU POR PROCESSOS ENZIMÁTICOS E/OU FERMENTATIVOS. O PROCESSO COBERTO PELA PRESENTE INVENÇÃO PERMITE OBTER CONCENTRADOS PROTEICOS E PEPTÍDICOS COM BAIXO TEOR EM LACTOSE E SAIS, QUE APRESENTAM ACTIVIDADES BIOLÓGICAS ÚTEIS PARA A FORMULAÇÃO DE PRODUTOS NAS INDÚSTRIA ALIMENTAR E FARMACÊUTICA. ASSIM, OS HIDROLISADOS, E AS SUAS FRACÇÕES OU PÉPTIDOS RESULTANTES DESTE PROCESSO, PODEM SER UTILIZADOS EM PRODUTOS ALIMENTARES, ACTUANDO COMO CONSERVANTES DOS MESMOS, OU ENTÃO, APÓS A SUA INGESTÃO, REFORÇANDO AS DEFESAS NATURAIS DO ORGANISMO. TAMBÉM PODEM SER UTILIZADOS NA ELABORAÇÃO DE PRODUTOS FARMACÊUTICOS DIRIGIDOS A DOENÇAS, PARTICULARMENTE PARA FACILITAR O CONTROLO DA PRESSÃO ARTERIAL E/OU INFECÇÕES BACTERIANAS, E PROCESSOS INFLAMATÓRIOS E ULCEROGÉNICOS. A INVENÇÃO AMPLIA AS APLICAÇÕES DAS PROTEÍNAS LÁCTEAS, CONTRIBUINDO ASSIM PARA O APROVEITAMENTO E REVALORIZAÇÃO EM PARTICULAR DO SORO DE LEITE.
PT105073A 2010-04-26 2010-04-26 Processo de obtenção de extractos peptídicos bioactivos através da hidrólise de proteínas de soro de leite com enzimas de cynara cardunculus, referidos extractos e respectivas utilizações PT105073A (pt)

Priority Applications (2)

Application Number Priority Date Filing Date Title
PT105073A PT105073A (pt) 2010-04-26 2010-04-26 Processo de obtenção de extractos peptídicos bioactivos através da hidrólise de proteínas de soro de leite com enzimas de cynara cardunculus, referidos extractos e respectivas utilizações
PCT/IB2011/051811 WO2011135513A1 (pt) 2010-04-26 2011-04-26 Processo de obtenção de extractos peptídicos bioactivos através da hidrólise de proteínas de soro de leite com enzimas de cynara cardunculus, referidos extractos e respectivas utilizações

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PT105073A PT105073A (pt) 2010-04-26 2010-04-26 Processo de obtenção de extractos peptídicos bioactivos através da hidrólise de proteínas de soro de leite com enzimas de cynara cardunculus, referidos extractos e respectivas utilizações

Publications (1)

Publication Number Publication Date
PT105073A true PT105073A (pt) 2011-10-26

Family

ID=44511825

Family Applications (1)

Application Number Title Priority Date Filing Date
PT105073A PT105073A (pt) 2010-04-26 2010-04-26 Processo de obtenção de extractos peptídicos bioactivos através da hidrólise de proteínas de soro de leite com enzimas de cynara cardunculus, referidos extractos e respectivas utilizações

Country Status (2)

Country Link
PT (1) PT105073A (pt)
WO (1) WO2011135513A1 (pt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11201909606RA (en) 2017-03-16 2019-11-28 Microsintesis Inc Probiotic molecules for reducing pathogen virulence
CN108546725B (zh) * 2018-01-23 2021-08-27 北京联合大学 一种利用马血制备的生物活性肽及其制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6919314B1 (en) 1998-06-17 2005-07-19 New Zealand Dairy Board Bioactive whey protein hydrolysate
CN101124261A (zh) * 2004-03-01 2008-02-13 派普特拉医药有限公司 酪蛋白衍生肽及其治疗用途
EP1967524A1 (en) 2007-03-06 2008-09-10 Friesland Brands B.V. Methods for producing ACE-inhibitory peptides from whey and peptides obtained thereby

Also Published As

Publication number Publication date
WO2011135513A1 (pt) 2011-11-03

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Effective date: 20100915

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