PT100329A - Composicoes a base de di-hidro-4-(3,5-di-terc-butil-4-hidroxi-benzilideno)-metil-2h-1,2-oxazin-3(4h)-ona sob forma micronizada - Google Patents

Composicoes a base de di-hidro-4-(3,5-di-terc-butil-4-hidroxi-benzilideno)-metil-2h-1,2-oxazin-3(4h)-ona sob forma micronizada

Info

Publication number
PT100329A
PT100329A PT100329A PT10032992A PT100329A PT 100329 A PT100329 A PT 100329A PT 100329 A PT100329 A PT 100329A PT 10032992 A PT10032992 A PT 10032992A PT 100329 A PT100329 A PT 100329A
Authority
PT
Portugal
Prior art keywords
micronized
terc
oxazin
benzylidene
hydro
Prior art date
Application number
PT100329A
Other languages
English (en)
Other versions
PT100329B (pt
Inventor
Sung J Lee
Original Assignee
Biofor Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biofor Ltd filed Critical Biofor Ltd
Publication of PT100329A publication Critical patent/PT100329A/pt
Publication of PT100329B publication Critical patent/PT100329B/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Cosmetics (AREA)
  • Lubricants (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
PT100329A 1991-04-05 1992-04-01 Composicoes a base de di-hidro-4-(3,5-di-terc-butil-4-hidroxi-benzilideno)-metil-2h-1,2-oxazin-3(4h)-ona sob forma micronizada PT100329B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/680,997 US5271944A (en) 1991-04-05 1991-04-05 Pharmacologically enhanced formulations

Publications (2)

Publication Number Publication Date
PT100329A true PT100329A (pt) 1993-07-30
PT100329B PT100329B (pt) 1999-06-30

Family

ID=24733350

Family Applications (1)

Application Number Title Priority Date Filing Date
PT100329A PT100329B (pt) 1991-04-05 1992-04-01 Composicoes a base de di-hidro-4-(3,5-di-terc-butil-4-hidroxi-benzilideno)-metil-2h-1,2-oxazin-3(4h)-ona sob forma micronizada

Country Status (16)

Country Link
US (1) US5271944A (pt)
EP (1) EP0599914B1 (pt)
AT (1) ATE155687T1 (pt)
AU (1) AU1876792A (pt)
CA (1) CA2052901C (pt)
CH (1) CH683824A5 (pt)
DE (1) DE69221150T2 (pt)
DK (1) DK0599914T3 (pt)
ES (1) ES2108130T3 (pt)
FR (1) FR2674754B1 (pt)
IE (1) IE74211B1 (pt)
IT (1) ITTO920303A1 (pt)
NZ (1) NZ242233A (pt)
PT (1) PT100329B (pt)
WO (1) WO1992017163A1 (pt)
ZA (1) ZA922482B (pt)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2684298B1 (fr) * 1991-12-03 1994-03-11 Rhone Poulenc Rorer Sa Nouvelles compositions pharmaceutiques solides a base de derives de lapiperidine substitues en 1,4.
AU701042B2 (en) * 1995-02-28 1999-01-21 Aventisub Llc Pharmaceutical composition for piperidinoalkanol compounds
EE04294B1 (et) * 1997-08-26 2004-06-15 Hoechst Marion Roussel, Inc. Farmatseutiline kompositsioon piperidinoalkanooldekongestandi kombineerimiseks
EP1541146B1 (en) 2000-04-24 2006-12-20 Teva Pharmaceutical Industries Ltd. Zolpidem hemitartrate solvate
EP1292304B1 (en) * 2000-04-24 2005-11-02 Teva Pharmaceutical Industries Ltd. Zolpidem hemitartrate
CA2439687A1 (en) 2001-03-01 2002-09-12 Hollis-Eden Pharmaceuticals, Inc. Use of certain steroids for treatment of blood cell deficiencies
US20060280761A1 (en) * 2002-03-11 2006-12-14 Health Plus International, Inc. Nanofluidized B-12 composition and process for treating pernicious anemia
US6861066B2 (en) * 2002-03-11 2005-03-01 Health Plus International Inc. Method for the delivery of a biologically active agent
BE1015641A4 (fr) * 2003-05-26 2005-07-05 Mariani Jean Paul Micronisation 70.
WO2005037821A2 (en) * 2003-10-16 2005-04-28 Teva Pharmaceutical Industries Ltd. Preparation of candesartan cilexetil
JP2007517803A (ja) * 2004-01-05 2007-07-05 テバ ファーマシューティカル インダストリーズ リミティド シルデナフィル塩基とクエン酸塩の製造方法
EP1713795A2 (en) * 2004-02-11 2006-10-25 Teva Pharmaceutical Industries Ltd. Candesartan cilexetil polymorphs
CA2582231A1 (en) 2004-09-29 2006-10-19 Hollis-Eden Pharmaceuticals, Inc. Steroid analogs and uses
US8252947B2 (en) 2008-04-03 2012-08-28 Harbor Therapeutics, Inc. Solid state forms of a pharmaceutical
TW201613888A (en) 2014-09-26 2016-04-16 Helsinn Healthcare Sa Crystalline forms of an NK-1 antagonist

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3033919A1 (de) * 1980-09-09 1982-04-22 Bayer Ag, 5090 Leverkusen Feste arzneizubereitungen enthaltend nifedipin und verfahren zu ihrer herstellung
DE3204126A1 (de) * 1982-02-06 1983-08-11 Bayer Ag, 5090 Leverkusen Pyrazoloxazine, -thiazine, -chinoline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
IT1187751B (it) * 1985-10-15 1987-12-23 Eurand Spa Procedimento per la preparazione di formulazioni solidi di nifedipina ad elevata biodisponibilita' e ad effetto prolungato e formulazioni cosi' ottenute
US4912093A (en) * 1986-10-01 1990-03-27 Marion Laboratories, Inc. Use of synthetic sulfated saccharides to enhance wound healing
DE3723327A1 (de) * 1987-07-15 1989-02-02 Hoechst Ag Substituierte thienoimidazol-derivate, verfahren zu ihrer herstellung, sie enthaltende pharmazeutische zubereitungen und ihre verwendung als magensaeuresekretionshemmer, magenschutzmittel sowie als medikament gegen intestinale entzuendungen
US4892870A (en) * 1988-08-01 1990-01-09 Biofor, Ltd. Oxaza heterocycles and pharmaceutical compositions containing same

Also Published As

Publication number Publication date
EP0599914B1 (en) 1997-07-23
CA2052901A1 (en) 1992-10-06
ZA922482B (en) 1992-12-30
EP0599914A1 (en) 1994-06-08
WO1992017163A1 (en) 1992-10-15
CA2052901C (en) 1997-12-23
DE69221150T2 (de) 1998-02-26
PT100329B (pt) 1999-06-30
NZ242233A (en) 1993-07-27
AU1876792A (en) 1992-11-02
IE921040A1 (en) 1992-10-07
ATE155687T1 (de) 1997-08-15
EP0599914A4 (en) 1994-08-24
DK0599914T3 (da) 1998-03-02
CH683824A5 (de) 1994-05-31
ITTO920303A0 (it) 1992-04-02
US5271944A (en) 1993-12-21
FR2674754B1 (fr) 1994-01-14
FR2674754A1 (fr) 1992-10-09
ITTO920303A1 (it) 1992-10-05
IE74211B1 (en) 1997-07-16
ES2108130T3 (es) 1997-12-16
DE69221150D1 (de) 1997-09-04

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Legal Events

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BB1A Laying open of patent application

Effective date: 19930303

FG3A Patent granted, date of granting

Effective date: 19990329

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 20010930