PL58138B1 - - Google Patents

Info

Publication number

PL58138B1

PL58138B1 PL110420A PL11042065A PL58138B1 PL 58138 B1 PL58138 B1 PL 58138B1 PL 110420 A PL110420 A PL 110420A PL 11042065 A PL11042065 A PL 11042065A PL 58138 B1 PL58138 B1 PL 58138B1

Authority

PL

Poland

Prior art keywords

penicillin

milk

preparation

dye

udder

Prior art date

1965-08-10

Links

• Espacenet
• Global Dossier
• Discuss

• 229930182555 Penicillin Natural products 0.000 claims description 24
• JGSARLDLIJGVTE-MBNYWOFBSA-N Penicillin G Chemical compound N([C@H]1[C@H]2SC([C@@H](N2C1=O)C(O)=O)(C)C)C(=O)CC1=CC=CC=C1 JGSARLDLIJGVTE-MBNYWOFBSA-N 0.000 claims description 24
• 229940049954 penicillin Drugs 0.000 claims description 24
• 239000008267 milk Substances 0.000 claims description 23
• 210000004080 milk Anatomy 0.000 claims description 23
• 238000002360 preparation method Methods 0.000 claims description 22
• 235000013336 milk Nutrition 0.000 claims description 21
• 239000003242 anti bacterial agent Substances 0.000 claims description 14
• 229940088710 antibiotic agent Drugs 0.000 claims description 10
• 210000000481 breast Anatomy 0.000 claims description 9
• 230000003115 biocidal effect Effects 0.000 claims description 7
• 238000000034 method Methods 0.000 claims description 6
• 241001465754 Metazoa Species 0.000 claims description 4
• 239000000725 suspension Substances 0.000 claims description 4
• 159000000007 calcium salts Chemical class 0.000 claims description 3
• 235000013365 dairy product Nutrition 0.000 claims description 3
• XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 3
• 238000004040 coloring Methods 0.000 claims 1
• RMWHEYSKPOGJRK-UHFFFAOYSA-N n-methyl-n-trityloxymethanamine Chemical compound C=1C=CC=CC=1C(C=1C=CC=CC=1)(ON(C)C)C1=CC=CC=C1 RMWHEYSKPOGJRK-UHFFFAOYSA-N 0.000 claims 1
• 239000000975 dye Substances 0.000 description 15
• 241000283690 Bos taurus Species 0.000 description 6
• KZDCMKVLEYCGQX-UDPGNSCCSA-N 2-(diethylamino)ethyl 4-aminobenzoate;(2s,5r,6r)-3,3-dimethyl-7-oxo-6-[(2-phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid;hydrate Chemical compound O.CCN(CC)CCOC(=O)C1=CC=C(N)C=C1.N([C@H]1[C@H]2SC([C@@H](N2C1=O)C(O)=O)(C)C)C(=O)CC1=CC=CC=C1 KZDCMKVLEYCGQX-UDPGNSCCSA-N 0.000 description 4
• 239000004615 ingredient Substances 0.000 description 4
• 239000003921 oil Substances 0.000 description 4
• 235000019198 oils Nutrition 0.000 description 4
• 239000000126 substance Substances 0.000 description 4
• 230000029142 excretion Effects 0.000 description 3
• 235000013305 food Nutrition 0.000 description 3
• 239000008159 sesame oil Substances 0.000 description 3
• 235000011803 sesame oil Nutrition 0.000 description 3
• 230000000007 visual effect Effects 0.000 description 3
• RTMBGDBBDQKNNZ-UHFFFAOYSA-L C.I. Acid Blue 3 Chemical compound [Ca+2].C1=CC(N(CC)CC)=CC=C1C(C=1C(=CC(=C(O)C=1)S([O-])(=O)=O)S([O-])(=O)=O)=C1C=CC(=[N+](CC)CC)C=C1.C1=CC(N(CC)CC)=CC=C1C(C=1C(=CC(=C(O)C=1)S([O-])(=O)=O)S([O-])(=O)=O)=C1C=CC(=[N+](CC)CC)C=C1 RTMBGDBBDQKNNZ-UHFFFAOYSA-L 0.000 description 2
• UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 description 2
• 229940027988 antiseptic and disinfectant nitrofuran derivative Drugs 0.000 description 2
• 239000001045 blue dye Substances 0.000 description 2
• 201000010099 disease Diseases 0.000 description 2
• 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
• 239000012153 distilled water Substances 0.000 description 2
• GNBHRKFJIUUOQI-UHFFFAOYSA-N fluorescein Chemical compound O1C(=O)C2=CC=CC=C2C21C1=CC=C(O)C=C1OC1=CC(O)=CC=C21 GNBHRKFJIUUOQI-UHFFFAOYSA-N 0.000 description 2
• 239000000576 food coloring agent Substances 0.000 description 2
• 239000000989 food dye Substances 0.000 description 2
• DNOYBZQNDHJASH-UHFFFAOYSA-N n-ethyl-n-trityloxyethanamine Chemical compound C=1C=CC=CC=1C(C=1C=CC=CC=1)(ON(CC)CC)C1=CC=CC=C1 DNOYBZQNDHJASH-UHFFFAOYSA-N 0.000 description 2
• IAIWVQXQOWNYOU-FPYGCLRLSA-N nitrofural Chemical class NC(=O)N\N=C\C1=CC=C([N+]([O-])=O)O1 IAIWVQXQOWNYOU-FPYGCLRLSA-N 0.000 description 2
• 239000001509 sodium citrate Substances 0.000 description 2
• UCSJYZPVAKXKNQ-HZYVHMACSA-N streptomycin Chemical compound CN[C@H]1[C@H](O)[C@@H](O)[C@H](CO)O[C@H]1O[C@@H]1[C@](C=O)(O)[C@H](C)O[C@H]1O[C@@H]1[C@@H](NC(N)=N)[C@H](O)[C@@H](NC(N)=N)[C@H](O)[C@H]1O UCSJYZPVAKXKNQ-HZYVHMACSA-N 0.000 description 2
• QTENRWWVYAAPBI-YCRXJPFRSA-N streptomycin sulfate Chemical compound OS(O)(=O)=O.OS(O)(=O)=O.OS(O)(=O)=O.CN[C@H]1[C@H](O)[C@@H](O)[C@H](CO)O[C@H]1O[C@@H]1[C@](C=O)(O)[C@H](C)O[C@H]1O[C@@H]1[C@@H](N=C(N)N)[C@H](O)[C@@H](N=C(N)N)[C@H](O)[C@H]1O.CN[C@H]1[C@H](O)[C@@H](O)[C@H](CO)O[C@H]1O[C@@H]1[C@](C=O)(O)[C@H](C)O[C@H]1O[C@@H]1[C@@H](N=C(N)N)[C@H](O)[C@@H](N=C(N)N)[C@H](O)[C@H]1O QTENRWWVYAAPBI-YCRXJPFRSA-N 0.000 description 2
• NVBFHJWHLNUMCV-UHFFFAOYSA-N sulfamide Chemical class NS(N)(=O)=O NVBFHJWHLNUMCV-UHFFFAOYSA-N 0.000 description 2
• HRXKRNGNAMMEHJ-UHFFFAOYSA-K trisodium citrate Chemical compound [Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O HRXKRNGNAMMEHJ-UHFFFAOYSA-K 0.000 description 2
• 229940038773 trisodium citrate Drugs 0.000 description 2
• 108010001478 Bacitracin Proteins 0.000 description 1
• 241000894006 Bacteria Species 0.000 description 1
• 241000283707 Capra Species 0.000 description 1
• 229930193140 Neomycin Natural products 0.000 description 1
• 239000005662 Paraffin oil Substances 0.000 description 1
• 241001494479 Pecora Species 0.000 description 1
• 239000013543 active substance Substances 0.000 description 1
• 239000000654 additive Substances 0.000 description 1
• 239000002671 adjuvant Substances 0.000 description 1
• 230000002411 adverse Effects 0.000 description 1
• 230000000844 anti-bacterial effect Effects 0.000 description 1
• 230000000845 anti-microbial effect Effects 0.000 description 1
• 239000007900 aqueous suspension Substances 0.000 description 1
• 229960003071 bacitracin Drugs 0.000 description 1
• 229930184125 bacitracin Natural products 0.000 description 1
• CLKOFPXJLQSYAH-ABRJDSQDSA-N bacitracin A Chemical compound C1SC([C@@H](N)[C@@H](C)CC)=N[C@@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](CCC(O)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]1C(=O)N[C@H](CCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CC=2N=CNC=2)C(=O)N[C@H](CC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)NCCCC1 CLKOFPXJLQSYAH-ABRJDSQDSA-N 0.000 description 1
• 238000009395 breeding Methods 0.000 description 1
• 230000001488 breeding effect Effects 0.000 description 1
• 239000004359 castor oil Substances 0.000 description 1
• 235000019438 castor oil Nutrition 0.000 description 1
• 235000019804 chlorophyll Nutrition 0.000 description 1
• 229930002875 chlorophyll Natural products 0.000 description 1
• ATNHDLDRLWWWCB-AENOIHSZSA-M chlorophyll a Chemical compound C1([C@@H](C(=O)OC)C(=O)C2=C3C)=C2N2C3=CC(C(CC)=C3C)=[N+]4C3=CC3=C(C=C)C(C)=C5N3[Mg-2]42[N+]2=C1[C@@H](CCC(=O)OC\C=C(/C)CCC[C@H](C)CCC[C@H](C)CCCC(C)C)[C@H](C)C2=C5 ATNHDLDRLWWWCB-AENOIHSZSA-M 0.000 description 1
• 230000000052 comparative effect Effects 0.000 description 1
• 238000011109 contamination Methods 0.000 description 1
• 239000003814 drug Substances 0.000 description 1
• 229940079593 drug Drugs 0.000 description 1
• 230000000694 effects Effects 0.000 description 1
• IINNWAYUJNWZRM-UHFFFAOYSA-L erythrosin B Chemical compound [Na+].[Na+].[O-]C(=O)C1=CC=CC=C1C1=C2C=C(I)C(=O)C(I)=C2OC2=C(I)C([O-])=C(I)C=C21 IINNWAYUJNWZRM-UHFFFAOYSA-L 0.000 description 1
• 235000012732 erythrosine Nutrition 0.000 description 1
• 239000004174 erythrosine Substances 0.000 description 1
• 229940011411 erythrosine Drugs 0.000 description 1
• 235000002864 food coloring agent Nutrition 0.000 description 1
• 125000005456 glyceride group Chemical group 0.000 description 1
• ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 description 1
• 150000002500 ions Chemical class 0.000 description 1
• 238000004519 manufacturing process Methods 0.000 description 1
• 238000012009 microbiological test Methods 0.000 description 1
• 239000002480 mineral oil Substances 0.000 description 1
• 239000000203 mixture Substances 0.000 description 1
• 229960004927 neomycin Drugs 0.000 description 1
• -1 paraffin oil Natural products 0.000 description 1
• 239000004177 patent blue V Substances 0.000 description 1
• 150000003839 salts Chemical class 0.000 description 1
• 230000003381 solubilizing effect Effects 0.000 description 1
• 241000894007 species Species 0.000 description 1
• 239000003381 stabilizer Substances 0.000 description 1
• 229960005322 streptomycin Drugs 0.000 description 1