PL449073A1 - Rekombinowane białko o właściwościach przeciwbakteryjnych zawierające aktywną domenę katalityczną CHAP, kompozycje je zawierające, zastosowania oraz sposoby je wykorzystujące - Google Patents
Rekombinowane białko o właściwościach przeciwbakteryjnych zawierające aktywną domenę katalityczną CHAP, kompozycje je zawierające, zastosowania oraz sposoby je wykorzystująceInfo
- Publication number
- PL449073A1 PL449073A1 PL449073A PL44907324A PL449073A1 PL 449073 A1 PL449073 A1 PL 449073A1 PL 449073 A PL449073 A PL 449073A PL 44907324 A PL44907324 A PL 44907324A PL 449073 A1 PL449073 A1 PL 449073A1
- Authority
- PL
- Poland
- Prior art keywords
- same
- chap
- active
- catalytic domain
- methods
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N63/00—Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
- A01N63/20—Bacteria; Substances produced thereby or obtained therefrom
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N63/00—Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
- A01N63/50—Isolated enzymes; Isolated proteins
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01P—BIOCIDAL, PEST REPELLANT, PEST ATTRACTANT OR PLANT GROWTH REGULATORY ACTIVITY OF CHEMICAL COMPOUNDS OR PREPARATIONS
- A01P1/00—Disinfectants; Antimicrobial compounds or mixtures thereof
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/189—Enzymes
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/80—Feeding-stuffs specially adapted for particular animals for aquatic animals, e.g. fish, crustaceans or molluscs
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
- C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y305/00—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5)
- C12Y305/01—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5) in linear amides (3.5.1)
- C12Y305/01028—N-Acetylmuramoyl-L-alanine amidase (3.5.1.28)
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Plant Pathology (AREA)
- Environmental Sciences (AREA)
- Food Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Animal Husbandry (AREA)
- Pest Control & Pesticides (AREA)
- Virology (AREA)
- Dentistry (AREA)
- Agronomy & Crop Science (AREA)
- Insects & Arthropods (AREA)
- Gastroenterology & Hepatology (AREA)
- Marine Sciences & Fisheries (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Birds (AREA)
- Biophysics (AREA)
- Communicable Diseases (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Abstract
Przedmiotem zgłoszenia jest rekombinowane białko o właściwościach przeciwbakteryjnych, zawierające aktywną domenę katalityczną CHAP o sekwencji aminokwasowej, o co najmniej 80% identyczności z sekwencją przedstawioną w SEQ ID No.2 pochodzącą z Listeria monocytogenes, kompozycje je zawierające, zastosowanie rekombinowanego białka jako czynnika przeciwbakteryjnego oraz sposób hamowania lub ograniczania wzrostu bakterii Gram (+) i/lub Gram (-) o zróżnicowanej strukturze peptydoglikanu.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL449073A PL449073A1 (pl) | 2024-06-29 | 2024-06-29 | Rekombinowane białko o właściwościach przeciwbakteryjnych zawierające aktywną domenę katalityczną CHAP, kompozycje je zawierające, zastosowania oraz sposoby je wykorzystujące |
| PCT/PL2025/050056 WO2026005629A1 (en) | 2024-06-29 | 2025-06-28 | Recombinant protein with antibacterial properties comprising an active chap catalytic domain, compositions comprising them, uses and methods utilizing thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL449073A PL449073A1 (pl) | 2024-06-29 | 2024-06-29 | Rekombinowane białko o właściwościach przeciwbakteryjnych zawierające aktywną domenę katalityczną CHAP, kompozycje je zawierające, zastosowania oraz sposoby je wykorzystujące |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL449073A1 true PL449073A1 (pl) | 2026-01-05 |
Family
ID=98222602
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL449073A PL449073A1 (pl) | 2024-06-29 | 2024-06-29 | Rekombinowane białko o właściwościach przeciwbakteryjnych zawierające aktywną domenę katalityczną CHAP, kompozycje je zawierające, zastosowania oraz sposoby je wykorzystujące |
Country Status (2)
| Country | Link |
|---|---|
| PL (1) | PL449073A1 (pl) |
| WO (1) | WO2026005629A1 (pl) |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008001342A1 (en) * | 2006-06-29 | 2008-01-03 | Teagasc, The Agriculture And Food Development Authority | Recombinant staphylococcal phage lysin as an antibacterial agent |
| WO2011076432A1 (en) * | 2009-12-23 | 2011-06-30 | Hyglos Invest Gmbh | Chimeric polypeptides and their use in bacterial decolonization |
-
2024
- 2024-06-29 PL PL449073A patent/PL449073A1/pl unknown
-
2025
- 2025-06-28 WO PCT/PL2025/050056 patent/WO2026005629A1/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008001342A1 (en) * | 2006-06-29 | 2008-01-03 | Teagasc, The Agriculture And Food Development Authority | Recombinant staphylococcal phage lysin as an antibacterial agent |
| WO2011076432A1 (en) * | 2009-12-23 | 2011-06-30 | Hyglos Invest Gmbh | Chimeric polypeptides and their use in bacterial decolonization |
Non-Patent Citations (4)
| Title |
|---|
| Baza danych GenBank; www.ncbi.nlm.nih.gov/protein/EAF9399118; CHAP domain-containing protein [Listeria monocytogenes]"; numer dostępu EAF9399118.1; 5 kwietnia 2019 (05.04.2019) * |
| BIERNE, H. ET AL.: "Microbiol Mol Biol Rev. 2007 Jun; 71(2): 377-97", LISTERIA MONOCYTOGENES SURFACE PROTEINS: FROM GENOME PREDICTIONS TO FUNCTION * |
| FENTON M. ET AL.: "Int J Microbiol. 2013; 2013: 625341", BACTERIOPHAGE-DERIVED PEPTIDASE CHAP(K) ELIMINATES AND PREVENTS STAPHYLOCOCCAL BIOFILMS * |
| HORGAN, M. ET AL.: "Appl Environ Microbiol. 2009. 75", PHAGE LYSIN LYSK CAN BE TRUNCATED TO ITS CHAP DOMAIN AND RETAIN LYTIC ACTIVITY AGAINST LIVE ANTIBIOTIC-RESISTANT STAPHYLOCOCCI. * |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2026005629A1 (en) | 2026-01-02 |
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