PL446045A1 - Sposób wytwarzania naproksenianu estru alkilowego L-leucyny - Google Patents

Sposób wytwarzania naproksenianu estru alkilowego L-leucyny

Info

Publication number
PL446045A1
PL446045A1 PL446045A PL44604521A PL446045A1 PL 446045 A1 PL446045 A1 PL 446045A1 PL 446045 A PL446045 A PL 446045A PL 44604521 A PL44604521 A PL 44604521A PL 446045 A1 PL446045 A1 PL 446045A1
Authority
PL
Poland
Prior art keywords
alkyl ester
naproxenate
producing
leucine
leucine alkyl
Prior art date
Application number
PL446045A
Other languages
English (en)
Other versions
PL245375B1 (pl
Inventor
Ewa Janus
Paula Ossowicz-Rupniewska
Joanna Klebeko
Ewelina Świątek
Original Assignee
Zachodniopomorski Uniwersytet Technologiczny W Szczecinie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zachodniopomorski Uniwersytet Technologiczny W Szczecinie filed Critical Zachodniopomorski Uniwersytet Technologiczny W Szczecinie
Priority to PL446045A priority Critical patent/PL245375B1/pl
Publication of PL446045A1 publication Critical patent/PL446045A1/pl
Publication of PL245375B1 publication Critical patent/PL245375B1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
    • C07C229/08—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to hydrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Przedmiotem zgłoszenia jest sposób wytwarzania naproksenianu estru alkilowego L-luecyny, o wzorze którego część kationową stanowi ester alkilowy L-leucyny, gdzie n=l-4, a część anionową stanowi anion (2S)-2-(6-metoksynaftalen-2-ylo)propanianowy, charakteryzuje się tym, że reakcji poddaje się chlorowodorek estru alkilowego L-leucyny z (2S)-2-(6-metoksynaftalen-2-ylo)propanianem sodu w równomolowej ilości, w środowisku rozpuszczalnika organicznego, w temperaturze od 25°C do 60°C, w czasie od 30 do 120 minut.
PL446045A 2021-09-28 2021-09-28 Sposób wytwarzania naproksenianu estru alkilowego L-leucyny PL245375B1 (pl)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PL446045A PL245375B1 (pl) 2021-09-28 2021-09-28 Sposób wytwarzania naproksenianu estru alkilowego L-leucyny

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL446045A PL245375B1 (pl) 2021-09-28 2021-09-28 Sposób wytwarzania naproksenianu estru alkilowego L-leucyny

Publications (2)

Publication Number Publication Date
PL446045A1 true PL446045A1 (pl) 2024-02-12
PL245375B1 PL245375B1 (pl) 2024-07-08

Family

ID=89855697

Family Applications (1)

Application Number Title Priority Date Filing Date
PL446045A PL245375B1 (pl) 2021-09-28 2021-09-28 Sposób wytwarzania naproksenianu estru alkilowego L-leucyny

Country Status (1)

Country Link
PL (1) PL245375B1 (pl)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2623098B1 (en) * 2012-02-03 2016-09-07 King Saud University Amide Amino Acid Esters of Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) as Potent Inhibitors of Tumor Cell Growth

Also Published As

Publication number Publication date
PL245375B1 (pl) 2024-07-08

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