PL439780A1 - Zastosowanie 2-metoksyestradiolu w leczeniu mastocytozy - Google Patents
Zastosowanie 2-metoksyestradiolu w leczeniu mastocytozyInfo
- Publication number
- PL439780A1 PL439780A1 PL439780A PL43978021A PL439780A1 PL 439780 A1 PL439780 A1 PL 439780A1 PL 439780 A PL439780 A PL 439780A PL 43978021 A PL43978021 A PL 43978021A PL 439780 A1 PL439780 A1 PL 439780A1
- Authority
- PL
- Poland
- Prior art keywords
- methoxyestradiol
- mastocytosis
- treatment
- cutaneous
- subject
- Prior art date
Links
- CQOQDQWUFQDJMK-SSTWWWIQSA-N 2-methoxy-17beta-estradiol Chemical compound C([C@@H]12)C[C@]3(C)[C@@H](O)CC[C@H]3[C@@H]1CCC1=C2C=C(OC)C(O)=C1 CQOQDQWUFQDJMK-SSTWWWIQSA-N 0.000 title abstract 2
- 208000008585 mastocytosis Diseases 0.000 title abstract 2
- 230000009885 systemic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Materials For Medical Uses (AREA)
Abstract
Przedmiotem zgłoszenia jest 2-metoksyestradiol do zastosowania w leczeniu mastocytozy, zwłaszcza jej postaci skórnej i/lub postaci układowej.
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL439780A PL244930B1 (pl) | 2021-12-08 | 2021-12-08 | Zastosowanie 2-metoksyestradiolu w leczeniu mastocytozy |
| PCT/PL2022/050091 WO2023106947A1 (en) | 2021-12-08 | 2022-12-08 | Use of 2-methoxyestradiol in the treatment of mastocytosis |
| EP22847278.3A EP4436582B1 (en) | 2021-12-08 | 2022-12-08 | 2-methoxyestradiol for use in the treatment of mastocytosis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL439780A PL244930B1 (pl) | 2021-12-08 | 2021-12-08 | Zastosowanie 2-metoksyestradiolu w leczeniu mastocytozy |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PL439780A1 true PL439780A1 (pl) | 2023-06-12 |
| PL244930B1 PL244930B1 (pl) | 2024-04-02 |
Family
ID=85036942
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL439780A PL244930B1 (pl) | 2021-12-08 | 2021-12-08 | Zastosowanie 2-metoksyestradiolu w leczeniu mastocytozy |
Country Status (3)
| Country | Link |
|---|---|
| EP (1) | EP4436582B1 (pl) |
| PL (1) | PL244930B1 (pl) |
| WO (1) | WO2023106947A1 (pl) |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0923376B1 (en) * | 1996-05-09 | 2004-11-03 | Amrad Operations Pty.,Ltd. | Use of steroids for treatment of asthma and airway diseases |
| DK1084146T3 (da) | 1998-05-13 | 2003-02-03 | Biotecon Ges Fuer Biotechnologische Entwicklung & Consulting Mbh | Hybridprotein til inhibering af degranuleringen af mastocyter og anvendelse deraf |
| JP2003009883A (ja) | 2001-07-05 | 2003-01-14 | Mitsubishi Pharma Corp | マスト細胞の細胞死誘発剤 |
| CA2615598C (en) * | 2005-07-20 | 2014-04-15 | Peter Valent | Compositions for treatment of systemic mastocytosis |
| FR2981945B1 (fr) | 2011-11-02 | 2016-09-23 | Centre Nat Rech Scient | Lignees de mastocytes humains, preparation et utilisations |
| WO2014188423A1 (en) | 2013-05-21 | 2014-11-27 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. | Treatment of mast cell related pathologies |
| EP3512515A1 (en) * | 2016-09-16 | 2019-07-24 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods and pharmaceutical compositions for the treatment of systemic mastocytosis |
| KR102867888B1 (ko) * | 2018-01-31 | 2025-10-13 | 데시페라 파마슈티칼스, 엘엘씨 | 비만 세포증의 치료를 위한 병용 요법 |
| US11839619B2 (en) * | 2019-09-16 | 2023-12-12 | The Regents Of The University Of California | Methods for treatment of pediatric systemic mastocytosis |
-
2021
- 2021-12-08 PL PL439780A patent/PL244930B1/pl unknown
-
2022
- 2022-12-08 WO PCT/PL2022/050091 patent/WO2023106947A1/en not_active Ceased
- 2022-12-08 EP EP22847278.3A patent/EP4436582B1/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP4436582B1 (en) | 2025-04-02 |
| EP4436582A1 (en) | 2024-10-02 |
| WO2023106947A1 (en) | 2023-06-15 |
| EP4436582C0 (en) | 2025-04-02 |
| PL244930B1 (pl) | 2024-04-02 |
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