PL436136A1 - Device for blood oxygenation with a membrane made of organic material with pore-forming, anti-inflammatory and anticoagulant properties - Google Patents
Device for blood oxygenation with a membrane made of organic material with pore-forming, anti-inflammatory and anticoagulant propertiesInfo
- Publication number
- PL436136A1 PL436136A1 PL436136A PL43613620A PL436136A1 PL 436136 A1 PL436136 A1 PL 436136A1 PL 436136 A PL436136 A PL 436136A PL 43613620 A PL43613620 A PL 43613620A PL 436136 A1 PL436136 A1 PL 436136A1
- Authority
- PL
- Poland
- Prior art keywords
- chamber
- gas mixture
- forming
- blood
- inflammatory
- Prior art date
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Abstract
Przedmiotem wynalazku jest urządzenie do utlenowania krwi (oksygenator do oksygenacji krwi), z membraną z organicznego materiału o właściwościach porotwórczych, przeciwzapalnych i przeciwkrzepliwych, stosowane do uzupełniania niedoborów tlenu we krwi niedotlenionej, zwłaszcza w przypadkach zespołu ostrej niewydolności oddechowej. Urządzenie zawiera komorę wymiany gazowej (1) o podłużnym kształcie w postaci walca prostego lub walca eliptycznego, w którego podstawach (2 i 2') wykonane są otwory przelotowe, przy czym z jednej strony komora (1) połączona jest gazoszczelnie ze zbiornikiem wyrównawczym (4) doprowadzającym do komory (1) mieszaninę gazową zawierającą tlen, mającym otwór wlotowy (5) mieszaniny gazowej z instalacji podającej tę mieszaninę, a z drugiej strony komora (1) połączona jest gazoszczelnie ze zbiornikiem odprowadzającym (6) z komory mieszaninę gazową, mającym otwór wylotowy (7) mieszaniny gazowej, a wewnątrz komory (1) umieszczona jest membrana w postaci wiązki kapilar (8) wykonanych z materiału półprzepuszczalnego, to jest przepuszczalnego dla cząsteczek mieszaniny gazowej a nieprzepuszczalnego dla cząstek krwi, których końce z obu stron zakotwione są w otworach przelotowych w podstawach (2, 2') komory (1), kapilary (8) naprężone są siłą naprężającą o wartości od 1 do 100 N, i są równoległe względem osi wzdłużnej komory (1) oraz nawzajem względem siebie, albo w korzystniejszym wariancie ukształtowane są spiralnie, to jest skręcone są wzdłuż osi wzdłużnej komory (1) o jednakowy kąt mieszczący się w zakresie od 15 do 720 stopni, ponadto w ściance bocznej komory (1) w pobliżu każdej podstawy (2, 2') komory, wykonane jest co najmniej po jednym otworze wlotowo/wylotowym (10) strumienia krwi, przy czym kapilary tworzące membranę mają postać rurek o średnicy zewnętrznej od 30 do 600 µm i wykonane są z organicznego materiału o właściwościach porotwórczych, przeciwzapalnych i przeciwkrzepliwych, składającego się z: - bazy w postaci polimeru fluorowego, korzystnie poli(tetrafluoroetylenu) (PTFE, teflon) lub polifluorku winylidenu (PVDF) lub kopolimeru tetrafluoroetylenu i heksafluoropropylenu (FEP), oraz - domieszki fondaparynuksu wbudowanej w mikrostrukturę materiału bazowego, w proporcji baza-domieszka od 80 ÷ 1 do 1200 ÷ 1.The subject of the invention is a device for blood oxygenation (oxygenator for blood oxygenation), with a membrane made of organic material with pore-forming, anti-inflammatory and anticoagulant properties, used to replenish oxygen deficiency in hypoxic blood, especially in cases of acute respiratory distress syndrome. The device comprises a gas exchange chamber (1) with an oblong shape in the form of a straight cylinder or an elliptical cylinder, the bases (2 and 2 ') of which are provided with through-holes, while on one side the chamber (1) is gas-tight connected to the equalizing tank (4). ) supplying the chamber (1) with an oxygen-containing gas mixture, having an inlet opening (5) of the gas mixture from the installation supplying this mixture, and on the other side the chamber (1) is gas-tight connected to a discharge tank (6) from the gas mixture chamber having an outlet opening (7) of the gas mixture, and inside the chamber (1) there is a membrane in the form of a bundle of capillaries (8) made of a semi-permeable material, i.e. permeable to gas mixture particles and impermeable to blood particles, the ends of which on both sides are anchored in through holes in the bases (2, 2 ') of the chamber (1), the capillaries (8) are under a tensile force of 1 to 100 N, and are parallel or Due to the longitudinal axis of the chamber (1) and to each other, or in a more preferred variant, they are spiral-shaped, i.e. they are twisted along the longitudinal axis of the chamber (1) by the same angle ranging from 15 to 720 degrees, moreover in the side wall of the chamber ( 1) near each base (2, 2 ') of the chamber, at least one blood stream inlet / outlet (10) is provided, the capillaries forming the membrane having the form of tubes with an outside diameter of 30 to 600 µm and made of organic material with pore-forming, anti-inflammatory and anticoagulant properties, consisting of: - a base in the form of a fluoropolymer, preferably poly (tetrafluoroethylene) (PTFE, Teflon) or polyvinylidene fluoride (PVDF) or a copolymer of tetrafluoroethylene and hexafluoropropylene and fondaparine (FEP), built into the microstructure of the base material, in the base-admixture ratio from 80 ÷ 1 to 1200 ÷ 1.
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PL436136A PL436136A1 (en) | 2020-11-27 | 2020-11-27 | Device for blood oxygenation with a membrane made of organic material with pore-forming, anti-inflammatory and anticoagulant properties |
PCT/IB2021/061017 WO2022113020A1 (en) | 2020-11-27 | 2021-11-26 | Blood oxygenator with an organic membrane |
EP21840667.6A EP4251226A1 (en) | 2020-11-27 | 2021-11-26 | Blood oxygenator with an organic membrane |
US18/254,853 US20240001016A1 (en) | 2020-11-27 | 2021-11-26 | Blood oxygenator with an organic membrane |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PL436136A PL436136A1 (en) | 2020-11-27 | 2020-11-27 | Device for blood oxygenation with a membrane made of organic material with pore-forming, anti-inflammatory and anticoagulant properties |
Publications (1)
Publication Number | Publication Date |
---|---|
PL436136A1 true PL436136A1 (en) | 2022-05-30 |
Family
ID=81751178
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL436136A PL436136A1 (en) | 2020-11-27 | 2020-11-27 | Device for blood oxygenation with a membrane made of organic material with pore-forming, anti-inflammatory and anticoagulant properties |
Country Status (1)
Country | Link |
---|---|
PL (1) | PL436136A1 (en) |
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2020
- 2020-11-27 PL PL436136A patent/PL436136A1/en unknown
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