PL4313058T3 - Kompozycja zawierająca roginolizyb i schemat dawkowania do leczenia nowotworu złośliwego lub choroby zapalnej lub autoimmunologicznej - Google Patents

Kompozycja zawierająca roginolizyb i schemat dawkowania do leczenia nowotworu złośliwego lub choroby zapalnej lub autoimmunologicznej

Info

Publication number
PL4313058T3
PL4313058T3 PL22719266.3T PL22719266T PL4313058T3 PL 4313058 T3 PL4313058 T3 PL 4313058T3 PL 22719266 T PL22719266 T PL 22719266T PL 4313058 T3 PL4313058 T3 PL 4313058T3
Authority
PL
Poland
Prior art keywords
roginolisib
inflammatory
composition
autoimmune disease
treating cancer
Prior art date
Application number
PL22719266.3T
Other languages
English (en)
Inventor
Catherine PICKERING
Lars Van Der Veen
Michael LAHN
Rebeca ZORRILLA
Zoë JOHNSON
Original Assignee
Ionctura Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB2104416.9A external-priority patent/GB202104416D0/en
Priority claimed from GBGB2117511.2A external-priority patent/GB202117511D0/en
Application filed by Ionctura Sa filed Critical Ionctura Sa
Publication of PL4313058T3 publication Critical patent/PL4313058T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/53751,4-Oxazines, e.g. morpholine
    • A61K31/53771,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • A61K9/2018Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/485Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4858Organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4866Organic macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Biophysics (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pyrane Compounds (AREA)
PL22719266.3T 2021-03-29 2022-03-29 Kompozycja zawierająca roginolizyb i schemat dawkowania do leczenia nowotworu złośliwego lub choroby zapalnej lub autoimmunologicznej PL4313058T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB2104416.9A GB202104416D0 (en) 2021-03-29 2021-03-29 Treatment reginmens
GBGB2117511.2A GB202117511D0 (en) 2021-12-03 2021-12-03 Treatment regimens
PCT/EP2022/058283 WO2022207646A1 (en) 2021-03-29 2022-03-29 A pi3k-delta inhibitor for use in treatment regimens

Publications (1)

Publication Number Publication Date
PL4313058T3 true PL4313058T3 (pl) 2025-06-23

Family

ID=81388915

Family Applications (1)

Application Number Title Priority Date Filing Date
PL22719266.3T PL4313058T3 (pl) 2021-03-29 2022-03-29 Kompozycja zawierająca roginolizyb i schemat dawkowania do leczenia nowotworu złośliwego lub choroby zapalnej lub autoimmunologicznej

Country Status (16)

Country Link
US (1) US20240058351A1 (pl)
EP (1) EP4313058B1 (pl)
AU (1) AU2022251843A1 (pl)
CA (1) CA3212731A1 (pl)
DK (1) DK4313058T3 (pl)
ES (1) ES3031295T3 (pl)
FI (1) FI4313058T3 (pl)
HR (1) HRP20250516T1 (pl)
HU (1) HUE071610T2 (pl)
LT (1) LT4313058T (pl)
MX (1) MX2023011442A (pl)
PL (1) PL4313058T3 (pl)
PT (1) PT4313058T (pl)
RS (1) RS66754B1 (pl)
SI (1) SI4313058T1 (pl)
WO (1) WO2022207646A1 (pl)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4676478A1 (en) * 2023-03-03 2026-01-14 iOnctura SA Combination of roginolisib and bcl-2 inhibitor in the treatment of haematological malignancy
EP4676454A1 (en) * 2023-03-03 2026-01-14 iOnctura SA Combination of roginolisib and hdac inhibitor in the treatment of haematological malignancy

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9073940B2 (en) * 2009-11-13 2015-07-07 Merck Serono Sa Tricyclic pyrazol amine derivatives
WO2014121901A1 (en) * 2013-02-07 2014-08-14 Merck Patent Gmbh Polymorphic forms

Also Published As

Publication number Publication date
MX2023011442A (es) 2023-10-18
LT4313058T (lt) 2025-05-26
ES3031295T3 (en) 2025-07-07
FI4313058T3 (fi) 2025-04-30
WO2022207646A1 (en) 2022-10-06
SI4313058T1 (sl) 2025-07-31
EP4313058A1 (en) 2024-02-07
PT4313058T (pt) 2025-06-02
RS66754B1 (sr) 2025-05-30
DK4313058T3 (da) 2025-05-12
HRP20250516T1 (hr) 2025-06-20
AU2022251843A1 (en) 2023-10-05
JP2024518685A (ja) 2024-05-02
US20240058351A1 (en) 2024-02-22
CA3212731A1 (en) 2022-10-06
HUE071610T2 (hu) 2025-09-28
EP4313058B1 (en) 2025-03-05

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