PL431093A1 - Cząsteczki bioreceptora, zastosowanie cząsteczek bioreceptora, czujniki zawierające elektrody modyfikowane tymi cząsteczkami bioreceptora, oraz sposób wykrywania bakterii i wirusów - Google Patents

Cząsteczki bioreceptora, zastosowanie cząsteczek bioreceptora, czujniki zawierające elektrody modyfikowane tymi cząsteczkami bioreceptora, oraz sposób wykrywania bakterii i wirusów

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Publication number
PL431093A1
PL431093A1 PL431093A PL43109319A PL431093A1 PL 431093 A1 PL431093 A1 PL 431093A1 PL 431093 A PL431093 A PL 431093A PL 43109319 A PL43109319 A PL 43109319A PL 431093 A1 PL431093 A1 PL 431093A1
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PL
Poland
Prior art keywords
bioreceptor
viruses
bioreceptor molecules
molecules
electrode
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Application number
PL431093A
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English (en)
Inventor
Izabela Załuska
Joanna KRECZKO
Piotr BARSKI
Dawid NIDZWORSKI
Elżbieta CZACZYK
Tomasz ŁĘGA
Karolina DZIĄBOWSKA
Krzysztof Urbański
Maciej SASOWSKI
Wioletta BIAŁOBRZESKA
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Sensdx Spółka Akcyjna
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Sensdx Spółka Akcyjna filed Critical Sensdx Spółka Akcyjna
Priority to PL431093A priority Critical patent/PL431093A1/pl
Priority to US17/641,342 priority patent/US20220365085A1/en
Priority to PCT/IB2020/056746 priority patent/WO2021048646A1/en
Priority to EP20768381.4A priority patent/EP4028410A1/en
Priority to PCT/IB2020/058364 priority patent/WO2021048750A1/en
Publication of PL431093A1 publication Critical patent/PL431093A1/pl

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/02—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance
    • G01N27/026—Dielectric impedance spectroscopy
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G01N33/5438—Electrodes

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Organic Chemistry (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Electrochemistry (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Przedmiotem wynalazku jest cząsteczka bioreceptora o podanym poniżej wzorze R1-alkil-C(O)NH-R2. Kolejnym przedmiotem wynalazku jest zastosowanie cząsteczek bioreceptora według wynalazku w elektrochemicznej spektroskopii impedancyjnej do wykrywania w jednej próbce jednej lub więcej patogennych bakterii i wirusów. Zgłoszenie, niniejsze, obejmuje też czujnik zawierający elektrodę, której powierzchnia jest pokryta warstwą metalu, charakteryzujący się tym, że warstwa ta jest modyfikowana cząsteczkami bioreceptora według wynalazku. Ponadto, przedmiotem wynalazku jest też sposób wykrywania w jednej próbce jednej lub więcej patogennych bakterii i wirusów za pomocą elektrochemicznej spektroskopii impedancyjnej, obejmujący następujące etapy: przemywanie i suszenie czujnika zawierającego elektrodę pokrytą metalem, modyfikacja powierzchni czujnika zawierającego elektrodę cząsteczkami bioreceptora, kalibracja układu pomiarowego, wykrywanie w jednej próbce jednej lub więcej patogennych bakterii i wirusów za pomocą układu pomiarowego przez obserwację zmian impedancji, charakteryzujący się tym, że modyfikację powierzchni czujnika zawierającego elektrodę przeprowadza się za pomocą cząsteczki bioreceptora według wynalazku.
PL431093A 2019-09-09 2019-09-09 Cząsteczki bioreceptora, zastosowanie cząsteczek bioreceptora, czujniki zawierające elektrody modyfikowane tymi cząsteczkami bioreceptora, oraz sposób wykrywania bakterii i wirusów PL431093A1 (pl)

Priority Applications (5)

Application Number Priority Date Filing Date Title
PL431093A PL431093A1 (pl) 2019-09-09 2019-09-09 Cząsteczki bioreceptora, zastosowanie cząsteczek bioreceptora, czujniki zawierające elektrody modyfikowane tymi cząsteczkami bioreceptora, oraz sposób wykrywania bakterii i wirusów
US17/641,342 US20220365085A1 (en) 2019-09-09 2020-07-17 Bioreceptor molecules, the use of bioreceptor molecules, sensors containing electrodes modified with the said bioreceptor molecules and the detection method of sars-cov-2 virus
PCT/IB2020/056746 WO2021048646A1 (en) 2019-09-09 2020-07-17 Bioreceptor molecules, the use of bioreceptor molecules, sensors containing electrodes modified with the said bioreceptor molecules and the detection method of sars-cov-2 virus
EP20768381.4A EP4028410A1 (en) 2019-09-09 2020-07-17 Bioreceptor molecules, the use of bioreceptor molecules, sensors containing electrodes modified with the said bioreceptor molecules and the detection method of sars-cov-2 virus
PCT/IB2020/058364 WO2021048750A1 (en) 2019-09-09 2020-09-09 Bioreceptor molecules, the use of bioreceptor molecules, sensors containing electrodes modified by the said bioreceptor molecules, and method of detecting bacteria and viruses

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL431093A PL431093A1 (pl) 2019-09-09 2019-09-09 Cząsteczki bioreceptora, zastosowanie cząsteczek bioreceptora, czujniki zawierające elektrody modyfikowane tymi cząsteczkami bioreceptora, oraz sposób wykrywania bakterii i wirusów

Publications (1)

Publication Number Publication Date
PL431093A1 true PL431093A1 (pl) 2021-03-22

Family

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PL431093A PL431093A1 (pl) 2019-09-09 2019-09-09 Cząsteczki bioreceptora, zastosowanie cząsteczek bioreceptora, czujniki zawierające elektrody modyfikowane tymi cząsteczkami bioreceptora, oraz sposób wykrywania bakterii i wirusów

Country Status (4)

Country Link
US (1) US20220365085A1 (pl)
EP (1) EP4028410A1 (pl)
PL (1) PL431093A1 (pl)
WO (2) WO2021048646A1 (pl)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023048151A1 (ja) * 2021-09-22 2023-03-30 塩野義製薬株式会社 ウイルス増殖阻害活性を有する環状ペプチド
IN202221051330A (pl) * 2022-09-08 2023-03-31
WO2024116168A1 (en) * 2022-11-30 2024-06-06 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Impedimetric detection using peptide and peptide mixtures

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8216797B2 (en) 2001-02-07 2012-07-10 Massachusetts Institute Of Technology Pathogen detection biosensor
CA2474458A1 (en) 2002-01-31 2003-08-07 Mitchell C. Sanders Method for detecting microorganisms
CN101123990A (zh) * 2004-10-01 2008-02-13 Mida科技有限公司 包含抗原和佐剂的纳米颗粒，和免疫原性结构
EP1919507A2 (en) * 2005-08-04 2008-05-14 Thomas William Rademacher Nanoparticles comprising antibacterial ligands
US8513001B2 (en) 2006-03-09 2013-08-20 The Regents Of The University Of California Method and apparatus for target detection using electrode-bound viruses
CA2744003C (en) 2008-11-21 2016-03-15 Mediomics Llc Biosensor for detecting multiple epitopes on a target
US20110171749A1 (en) 2009-03-02 2011-07-14 Board Of Trustees Of Michigan State University Nanoparticle tracer-based electrochemical dna sensor for detection of pathogens-amplification by a universal nano-tracer (aunt)
PL239378B1 (pl) * 2018-02-07 2021-11-29 Sensdx Spolka Z Ograniczona Odpowiedzialnoscia Czujnik do pomiarów impedancyjnych próbki czynnika biologicznego lub chemicznego oraz sposób wykrywania czynnika biologicznego lub chemicznego w próbce za pomocą takiego czujnika

Also Published As

Publication number Publication date
EP4028410A1 (en) 2022-07-20
WO2021048750A1 (en) 2021-03-18
US20220365085A1 (en) 2022-11-17
WO2021048646A1 (en) 2021-03-18

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