PL429950A1 - Oil-in-water emulsion for use in eye drops as a carrier for oil-soluble ophthalmic drug substances - Google Patents
Oil-in-water emulsion for use in eye drops as a carrier for oil-soluble ophthalmic drug substancesInfo
- Publication number
- PL429950A1 PL429950A1 PL429950A PL42995019A PL429950A1 PL 429950 A1 PL429950 A1 PL 429950A1 PL 429950 A PL429950 A PL 429950A PL 42995019 A PL42995019 A PL 42995019A PL 429950 A1 PL429950 A1 PL 429950A1
- Authority
- PL
- Poland
- Prior art keywords
- oil
- carrier
- water emulsion
- eye drops
- drug substances
- Prior art date
Links
- 239000003889 eye drop Substances 0.000 title abstract 2
- 229940012356 eye drops Drugs 0.000 title abstract 2
- 239000007764 o/w emulsion Substances 0.000 title abstract 2
- 239000000126 substance Substances 0.000 title abstract 2
- 239000003732 agents acting on the eye Substances 0.000 title 1
- 229940023490 ophthalmic product Drugs 0.000 title 1
- 239000002253 acid Substances 0.000 abstract 3
- 150000007513 acids Chemical class 0.000 abstract 2
- 150000002148 esters Chemical class 0.000 abstract 2
- JKQXZKUSFCKOGQ-JLGXGRJMSA-N (3R,3'R)-beta,beta-carotene-3,3'-diol Chemical compound C([C@H](O)CC=1C)C(C)(C)C=1/C=C/C(/C)=C/C=C/C(/C)=C/C=C/C=C(C)C=CC=C(C)C=CC1=C(C)C[C@@H](O)CC1(C)C JKQXZKUSFCKOGQ-JLGXGRJMSA-N 0.000 abstract 1
- JKQXZKUSFCKOGQ-LQFQNGICSA-N Z-zeaxanthin Natural products C([C@H](O)CC=1C)C(C)(C)C=1C=CC(C)=CC=CC(C)=CC=CC=C(C)C=CC=C(C)C=CC1=C(C)C[C@@H](O)CC1(C)C JKQXZKUSFCKOGQ-LQFQNGICSA-N 0.000 abstract 1
- QOPRSMDTRDMBNK-RNUUUQFGSA-N Zeaxanthin Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CCC(O)C1(C)C)C=CC=C(/C)C=CC2=C(C)CC(O)CC2(C)C QOPRSMDTRDMBNK-RNUUUQFGSA-N 0.000 abstract 1
- JKQXZKUSFCKOGQ-LOFNIBRQSA-N all-trans-Zeaxanthin Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CC(O)CC1(C)C)C=CC=C(/C)C=CC2=C(C)CC(O)CC2(C)C JKQXZKUSFCKOGQ-LOFNIBRQSA-N 0.000 abstract 1
- 239000008346 aqueous phase Substances 0.000 abstract 1
- 235000014113 dietary fatty acids Nutrition 0.000 abstract 1
- 239000003995 emulsifying agent Substances 0.000 abstract 1
- 229930195729 fatty acid Natural products 0.000 abstract 1
- 239000000194 fatty acid Substances 0.000 abstract 1
- 150000004665 fatty acids Chemical class 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000003921 oil Substances 0.000 abstract 1
- 235000019198 oils Nutrition 0.000 abstract 1
- 235000020660 omega-3 fatty acid Nutrition 0.000 abstract 1
- 239000012071 phase Substances 0.000 abstract 1
- 150000005846 sugar alcohols Polymers 0.000 abstract 1
- 239000004094 surface-active agent Substances 0.000 abstract 1
- KBPHJBAIARWVSC-XQIHNALSSA-N trans-lutein Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CC(O)CC1(C)C)C=CC=C(/C)C=CC2C(=CC(O)CC2(C)C)C KBPHJBAIARWVSC-XQIHNALSSA-N 0.000 abstract 1
- 235000021122 unsaturated fatty acids Nutrition 0.000 abstract 1
- 150000004670 unsaturated fatty acids Chemical class 0.000 abstract 1
- 235000015112 vegetable and seed oil Nutrition 0.000 abstract 1
- 239000008158 vegetable oil Substances 0.000 abstract 1
- 235000010930 zeaxanthin Nutrition 0.000 abstract 1
- 229940043269 zeaxanthin Drugs 0.000 abstract 1
- 239000001775 zeaxanthin Substances 0.000 abstract 1
Landscapes
- Medicinal Preparation (AREA)
Abstract
Przedmiotem wynalazku jest emulsja typu olej w wodzie do zastosowania w kroplach do oczu jako nośnik dla okulistycznych substancji leczniczych rozpuszczalnych w olejach, zawierająca fazę olejową zawierającą kwasy tłuszczowe lub nienasycone kwasy tłuszczowe lub ich estry oraz fazę wodną zawierającą co najmniej jeden emulgator, związek powierzchniowo czynny, lub ich mieszaninę charakteryzująca się tym, że zawiera co najmniej jeden olej roślinny jako źródło kwasów omega-3 oraz kwasów omega-6, w postaci kwasowej lub w postaci estrów alkoholi poliwodorotlenowych, oraz zeaksantynę.The present invention relates to an oil-in-water emulsion for use in eye drops as a carrier for oil-soluble ophthalmic medicinal substances, comprising an oil phase containing fatty acids or unsaturated fatty acids or their esters, and an aqueous phase containing at least one emulsifier, a surfactant, or a mixture thereof characterized in that it comprises at least one vegetable oil as a source of omega-3 acids and omega-6 acids, in acid form or in the form of polyhydric alcohol esters, and zeaxanthin.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL429950A PL239957B1 (en) | 2019-05-16 | 2019-05-16 | Oil-in-water emulsion for use in eye drops as a carrier for oil-soluble ophthalmic drug substances |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL429950A PL239957B1 (en) | 2019-05-16 | 2019-05-16 | Oil-in-water emulsion for use in eye drops as a carrier for oil-soluble ophthalmic drug substances |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PL429950A1 true PL429950A1 (en) | 2020-11-30 |
| PL239957B1 PL239957B1 (en) | 2022-01-31 |
Family
ID=73551754
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL429950A PL239957B1 (en) | 2019-05-16 | 2019-05-16 | Oil-in-water emulsion for use in eye drops as a carrier for oil-soluble ophthalmic drug substances |
Country Status (1)
| Country | Link |
|---|---|
| PL (1) | PL239957B1 (en) |
-
2019
- 2019-05-16 PL PL429950A patent/PL239957B1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PL239957B1 (en) | 2022-01-31 |
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