PL424003A1 - Kwas 5-(aminometylo)-2,6-dimetylohept-6-enowy i sposób jego otrzymywania - Google Patents
Kwas 5-(aminometylo)-2,6-dimetylohept-6-enowy i sposób jego otrzymywaniaInfo
- Publication number
- PL424003A1 PL424003A1 PL424003A PL42400317A PL424003A1 PL 424003 A1 PL424003 A1 PL 424003A1 PL 424003 A PL424003 A PL 424003A PL 42400317 A PL42400317 A PL 42400317A PL 424003 A1 PL424003 A1 PL 424003A1
- Authority
- PL
- Poland
- Prior art keywords
- dimethylhept
- aminomethyl
- enoic acid
- formula
- obtaining
- Prior art date
Links
- VHBRHUJQPLFVCD-UHFFFAOYSA-N 5-(aminomethyl)-2,6-dimethylhept-6-enoic acid Chemical compound NCC(CCC(C(=O)O)C)C(=C)C VHBRHUJQPLFVCD-UHFFFAOYSA-N 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 abstract 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- 238000006243 chemical reaction Methods 0.000 abstract 2
- ZAFNJMIOTHYJRJ-UHFFFAOYSA-N Diisopropyl ether Chemical compound CC(C)OC(C)C ZAFNJMIOTHYJRJ-UHFFFAOYSA-N 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108010084311 Novozyme 435 Proteins 0.000 abstract 1
- 238000001914 filtration Methods 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 150000003951 lactams Chemical class 0.000 abstract 1
- 230000000144 pharmacologic effect Effects 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 239000000758 substrate Substances 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Landscapes
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Przedmiotem zgłoszenia jest kwas 5-(aminometylo)-2,6-dimetylohept-6-enowy o wzorze 1, znajdujący zastosowanie jako substancja farmakologiczna lub substrat do dalszych syntez w przemyśle farmaceutycznym. Zgłoszenie obejmuje także sposób otrzymywania kwasu 5-(aminometylo)-2,6-dimetylohept-6-enowego o wzorze 1, charakteryzujący się tym, że we fiolce o pojemności 3,0 ml umieszcza się 0,01 g (0,0598 mmola) laktamu dihydrokarwonu o wzorze 2 i rozpuszcza się w 1,5 ml eteru diizopropylowego, dodając 16 µl H2O oraz 180 mg preparatu Novozym 435. Zawartość fiolki miesza się na mieszadle magnetycznym (150 rpm), przy jednoczesnym jej odgrzewaniu temperatury do 50°C. Reakcję prowadzi się przez 24 h. Po tym czasie reakcję kończy się, oddzielając enzym poprzez sączenie. Rozpuszczalnik odparowuje się, a produkt krystalizuje z mieszaniny eter dietylowy: etanol.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL424003A PL231975B1 (pl) | 2017-12-22 | 2017-12-22 | Kwas 5-(aminometylo)-2,6-dimetylohept-6-enowy i sposób jego otrzymywania |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL424003A PL231975B1 (pl) | 2017-12-22 | 2017-12-22 | Kwas 5-(aminometylo)-2,6-dimetylohept-6-enowy i sposób jego otrzymywania |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PL424003A1 true PL424003A1 (pl) | 2018-08-13 |
| PL231975B1 PL231975B1 (pl) | 2019-04-30 |
Family
ID=63112958
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL424003A PL231975B1 (pl) | 2017-12-22 | 2017-12-22 | Kwas 5-(aminometylo)-2,6-dimetylohept-6-enowy i sposób jego otrzymywania |
Country Status (1)
| Country | Link |
|---|---|
| PL (1) | PL231975B1 (pl) |
-
2017
- 2017-12-22 PL PL424003A patent/PL231975B1/pl unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PL231975B1 (pl) | 2019-04-30 |
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