PL4222147T3 - Pochodne tiadiazolonu i ich zastosowanie jako agonistów ampk w leczeniu cukrzycy i powiązanych z nią zaburzeń - Google Patents
Pochodne tiadiazolonu i ich zastosowanie jako agonistów ampk w leczeniu cukrzycy i powiązanych z nią zaburzeńInfo
- Publication number
- PL4222147T3 PL4222147T3 PL21816508.2T PL21816508T PL4222147T3 PL 4222147 T3 PL4222147 T3 PL 4222147T3 PL 21816508 T PL21816508 T PL 21816508T PL 4222147 T3 PL4222147 T3 PL 4222147T3
- Authority
- PL
- Poland
- Prior art keywords
- thiadiazolone
- diabetes
- derivatives
- treatment
- related disorders
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/433—Thidiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/01—Five-membered rings
- C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
- C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
- C07D285/08—1,2,4-Thiadiazoles; Hydrogenated 1,2,4-thiadiazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6536—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having nitrogen and sulfur atoms with or without oxygen atoms, as the only ring hetero atoms
- C07F9/6539—Five-membered rings
- C07F9/65392—Five-membered rings containing two nitrogen atoms
- C07F9/65397—Five-membered rings containing two nitrogen atoms having the two nitrogen atoms in positions 1 and 3
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Diabetes (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Child & Adolescent Psychology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB2015585.9A GB202015585D0 (en) | 2020-10-01 | 2020-10-01 | New compounds |
| PCT/GB2021/052535 WO2022069894A1 (en) | 2020-10-01 | 2021-09-30 | Thiadiazolone derivatives and their use as ampk agonists for the treatment of diabetes and related disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL4222147T3 true PL4222147T3 (pl) | 2025-06-09 |
Family
ID=73223766
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL21816508.2T PL4222147T3 (pl) | 2020-10-01 | 2021-09-30 | Pochodne tiadiazolonu i ich zastosowanie jako agonistów ampk w leczeniu cukrzycy i powiązanych z nią zaburzeń |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20230382930A1 (pl) |
| EP (1) | EP4222147B1 (pl) |
| JP (1) | JP7793614B2 (pl) |
| KR (1) | KR20230079163A (pl) |
| CN (1) | CN116368141B (pl) |
| AU (1) | AU2021352146A1 (pl) |
| CA (1) | CA3193947A1 (pl) |
| ES (1) | ES3018732T3 (pl) |
| GB (1) | GB202015585D0 (pl) |
| HU (1) | HUE071685T2 (pl) |
| MX (1) | MX2023003825A (pl) |
| PL (1) | PL4222147T3 (pl) |
| WO (1) | WO2022069894A1 (pl) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11691954B2 (en) | 2019-10-18 | 2023-07-04 | Betagenon Ab | Formulations |
| GB202112529D0 (en) * | 2021-09-02 | 2021-10-20 | Betagenon Bio Ab | New compounds |
| WO2024075784A1 (ja) * | 2022-10-05 | 2024-04-11 | 沢井製薬株式会社 | ニトロソ化反応を抑制する添加剤の選定方法及びニトロソ化合物の生成を抑制した製剤 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102596923B (zh) * | 2009-07-08 | 2015-04-29 | 波罗的海生物公司 | 1,2,4-噻唑烷-3-酮衍生物及其在癌症治疗中的用途 |
| WO2013108026A1 (en) * | 2012-01-17 | 2013-07-25 | Baltic Bio Ab | Thiadiazolone derivatives useful in the treatment of diabetes |
| CA3118629A1 (en) * | 2018-11-05 | 2020-05-14 | Balticgruppen Bio Ab | Methods of treating diabetes in severe insulin-resistant diabetic subjects |
-
2020
- 2020-10-01 GB GBGB2015585.9A patent/GB202015585D0/en not_active Ceased
-
2021
- 2021-09-30 HU HUE21816508A patent/HUE071685T2/hu unknown
- 2021-09-30 WO PCT/GB2021/052535 patent/WO2022069894A1/en not_active Ceased
- 2021-09-30 JP JP2023520459A patent/JP7793614B2/ja active Active
- 2021-09-30 PL PL21816508.2T patent/PL4222147T3/pl unknown
- 2021-09-30 AU AU2021352146A patent/AU2021352146A1/en active Pending
- 2021-09-30 US US18/028,192 patent/US20230382930A1/en active Pending
- 2021-09-30 KR KR1020237014527A patent/KR20230079163A/ko active Pending
- 2021-09-30 CN CN202180067894.4A patent/CN116368141B/zh active Active
- 2021-09-30 EP EP21816508.2A patent/EP4222147B1/en active Active
- 2021-09-30 ES ES21816508T patent/ES3018732T3/es active Active
- 2021-09-30 MX MX2023003825A patent/MX2023003825A/es unknown
- 2021-09-30 CA CA3193947A patent/CA3193947A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AU2021352146A1 (en) | 2023-06-01 |
| US20230382930A1 (en) | 2023-11-30 |
| JP7793614B2 (ja) | 2026-01-05 |
| EP4222147C0 (en) | 2025-03-19 |
| ES3018732T3 (en) | 2025-05-19 |
| WO2022069894A1 (en) | 2022-04-07 |
| CN116368141B (zh) | 2025-09-23 |
| JP2023543924A (ja) | 2023-10-18 |
| CN116368141A (zh) | 2023-06-30 |
| CA3193947A1 (en) | 2022-04-07 |
| EP4222147A1 (en) | 2023-08-09 |
| GB202015585D0 (en) | 2020-11-18 |
| HUE071685T2 (hu) | 2025-09-28 |
| KR20230079163A (ko) | 2023-06-05 |
| MX2023003825A (es) | 2023-06-06 |
| EP4222147B1 (en) | 2025-03-19 |
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