PL418942A1 - 1'2'-Di[(3,7,11,15-tetramethyl-3-vinylhexadecyl]-sn-glycero-3'-phosphocholine and method for obtaining it - Google Patents

1'2'-Di[(3,7,11,15-tetramethyl-3-vinylhexadecyl]-sn-glycero-3'-phosphocholine and method for obtaining it

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Publication number
PL418942A1
PL418942A1 PL418942A PL41894216A PL418942A1 PL 418942 A1 PL418942 A1 PL 418942A1 PL 418942 A PL418942 A PL 418942A PL 41894216 A PL41894216 A PL 41894216A PL 418942 A1 PL418942 A1 PL 418942A1
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PL
Poland
Prior art keywords
phosphocholine
tetramethyl
vinylhexadecyl
glycero
obtaining
Prior art date
Application number
PL418942A
Other languages
Polish (pl)
Other versions
PL229269B1 (en
Inventor
Anna Gliszczyńska
Natalia Niezgoda
Witold Gładkowski
Original Assignee
Uniwersytet Przyrodniczy we Wrocławiu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Uniwersytet Przyrodniczy we Wrocławiu filed Critical Uniwersytet Przyrodniczy we Wrocławiu
Priority to PL418942A priority Critical patent/PL229269B1/en
Publication of PL418942A1 publication Critical patent/PL418942A1/en
Publication of PL229269B1 publication Critical patent/PL229269B1/en

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Abstract

Zgłoszenie dotyczy 1',2'-di[(3,7,11,15-tetrametylo-3-winyloheksadecylo]-sn-glicero-3'-fosfocholina o wzorze 1 oraz sposobu jej otrzymywania na drodze estryfikacji kwasu 3,7,11,15-tetrametylo-3-winyloheksadekanowego kompleksem sn-glicero-3-fosfocholiny i chlorku kadmu z udziałem czynnika sprzęgającego jakim jest N,N'-dicykloheksylokarbodiimid oraz w obecności 4-dimetyloaminopirydyny w środowisku bezwodnego chlorku metylenu. Rozwiązanie może znaleźć zastosowanie w terapii chorób nowotworowych.The application relates to 1 ', 2'-di [(3,7,11,15-tetramethyl-3-vinylhexadecyl] -sn-glycero-3'-phosphocholine of formula 1 and the method for its preparation by acid esterification 3,7,11 , 15-tetramethyl-3-vinylhexadecane complex of sn-glycerol-3-phosphocholine and cadmium chloride with the coupling agent N, N'-dicyclohexylcarbodiimide and in the presence of 4-dimethylaminopyridine in anhydrous methylene chloride. The solution may find application in the therapy of diseases cancer.

PL418942A 2016-09-30 2016-09-30 1'2'-Di[(3,7,11,15-tetramethyl-3-vinylhexadecyl]-sn-glycero-3'-phosphocholine and method for obtaining it PL229269B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PL418942A PL229269B1 (en) 2016-09-30 2016-09-30 1'2'-Di[(3,7,11,15-tetramethyl-3-vinylhexadecyl]-sn-glycero-3'-phosphocholine and method for obtaining it

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL418942A PL229269B1 (en) 2016-09-30 2016-09-30 1'2'-Di[(3,7,11,15-tetramethyl-3-vinylhexadecyl]-sn-glycero-3'-phosphocholine and method for obtaining it

Publications (2)

Publication Number Publication Date
PL418942A1 true PL418942A1 (en) 2017-03-13
PL229269B1 PL229269B1 (en) 2018-06-29

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ID=58231136

Family Applications (1)

Application Number Title Priority Date Filing Date
PL418942A PL229269B1 (en) 2016-09-30 2016-09-30 1'2'-Di[(3,7,11,15-tetramethyl-3-vinylhexadecyl]-sn-glycero-3'-phosphocholine and method for obtaining it

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PL (1) PL229269B1 (en)

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Publication number Publication date
PL229269B1 (en) 2018-06-29

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