PL4135849T3 - Terapia skojarzona miv-818/lenwatynib na raka wątroby - Google Patents

Terapia skojarzona miv-818/lenwatynib na raka wątroby

Info

Publication number
PL4135849T3
PL4135849T3 PL21787576.4T PL21787576T PL4135849T3 PL 4135849 T3 PL4135849 T3 PL 4135849T3 PL 21787576 T PL21787576 T PL 21787576T PL 4135849 T3 PL4135849 T3 PL 4135849T3
Authority
PL
Poland
Prior art keywords
lenvatinib
miv
combination therapy
liver cancer
liver
Prior art date
Application number
PL21787576.4T
Other languages
English (en)
Inventor
Fredrik ÖBERG
Original Assignee
Medivir Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medivir Ab filed Critical Medivir Ab
Publication of PL4135849T3 publication Critical patent/PL4135849T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/683Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A61K31/685Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/683Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A61K31/688Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols both hydroxy compounds having nitrogen atoms, e.g. sphingomyelins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/664Amides of phosphorus acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)
  • Surgical Instruments (AREA)
PL21787576.4T 2020-04-15 2021-04-14 Terapia skojarzona miv-818/lenwatynib na raka wątroby PL4135849T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE2050430 2020-04-15
PCT/SE2021/050338 WO2021211039A1 (en) 2020-04-15 2021-04-14 Miv-818/lenvatinib combination therapy for liver cancer

Publications (1)

Publication Number Publication Date
PL4135849T3 true PL4135849T3 (pl) 2025-07-14

Family

ID=78084457

Family Applications (1)

Application Number Title Priority Date Filing Date
PL21787576.4T PL4135849T3 (pl) 2020-04-15 2021-04-14 Terapia skojarzona miv-818/lenwatynib na raka wątroby

Country Status (13)

Country Link
US (1) US20240024342A1 (pl)
EP (1) EP4135849B1 (pl)
JP (1) JP7709456B2 (pl)
KR (1) KR20230003522A (pl)
CN (1) CN115485029A (pl)
AU (1) AU2021255043B9 (pl)
CA (1) CA3174940A1 (pl)
ES (1) ES3027841T3 (pl)
HR (1) HRP20250669T1 (pl)
HU (1) HUE071473T2 (pl)
PL (1) PL4135849T3 (pl)
TW (1) TW202200140A (pl)
WO (1) WO2021211039A1 (pl)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113453685A (zh) * 2019-02-18 2021-09-28 美迪维尔公司 使用口服给药的二氧戊环核苷酸与抗pd1或抗pdl1单克隆抗体的组合治疗肝癌的方法
TW202444368A (zh) * 2023-03-30 2024-11-16 瑞典商米迪維艾克提伯拉公司 以氟曲沙他濱布洛帕胺(fostroxacitabine bralpamide)、免疫檢查點抑制劑及vegf拮抗劑治療肝癌之方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ729118A (en) * 2014-08-25 2022-02-25 Medivir Ab Dioxolane analogues of uridine for the treatment of cancer
KR102703122B1 (ko) * 2016-03-02 2024-09-04 메디비르 아크티에보라그 소라페닙 또는 레고라페닙과 트록사시타빈의 포스포라미데이트 전구약물의 병용 요법
MX2019013014A (es) * 2017-05-16 2020-08-06 Eisai R&D Man Co Ltd Tratamiento de carcinoma hepatocelular.
CN113453685A (zh) * 2019-02-18 2021-09-28 美迪维尔公司 使用口服给药的二氧戊环核苷酸与抗pd1或抗pdl1单克隆抗体的组合治疗肝癌的方法
AU2020321945B2 (en) * 2019-07-26 2025-02-13 Espervita Therapeutics, Inc. Functionalized long-chain hydrocarbon mono- and di-carboxylic acids useful for the prevention or treatment of disease

Also Published As

Publication number Publication date
TW202200140A (zh) 2022-01-01
ES3027841T3 (en) 2025-06-17
JP2023522325A (ja) 2023-05-30
CN115485029A (zh) 2022-12-16
EP4135849A1 (en) 2023-02-22
CA3174940A1 (en) 2021-10-21
EP4135849B1 (en) 2025-03-19
JP7709456B2 (ja) 2025-07-16
HRP20250669T1 (hr) 2025-08-01
KR20230003522A (ko) 2023-01-06
AU2021255043B9 (en) 2025-07-10
AU2021255043A1 (en) 2022-11-03
US20240024342A1 (en) 2024-01-25
HUE071473T2 (hu) 2025-09-28
EP4135849C0 (en) 2025-03-19
WO2021211039A1 (en) 2021-10-21
AU2021255043B2 (en) 2025-06-05
EP4135849A4 (en) 2024-04-17

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