PL406989A1 - Profile of micro RNA in blood as the test for detecting lung cancer - Google Patents

Profile of micro RNA in blood as the test for detecting lung cancer

Info

Publication number
PL406989A1
PL406989A1 PL406989A PL40698914A PL406989A1 PL 406989 A1 PL406989 A1 PL 406989A1 PL 406989 A PL406989 A PL 406989A PL 40698914 A PL40698914 A PL 40698914A PL 406989 A1 PL406989 A1 PL 406989A1
Authority
PL
Poland
Prior art keywords
lung cancer
test
blood
profile
micro rna
Prior art date
Application number
PL406989A
Other languages
Polish (pl)
Inventor
Witold Rzyman
Rafał Dziadziuszko
Jacek Jassem
Joanna Polańska
Piotr Widłak
Original Assignee
Gdański Uniwersytet Medyczny
Centrum Onkologii - Instytut Im. Marii Skłodowskiej-Curie, Oddział W Gliwicach
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gdański Uniwersytet Medyczny, Centrum Onkologii - Instytut Im. Marii Skłodowskiej-Curie, Oddział W Gliwicach filed Critical Gdański Uniwersytet Medyczny
Priority to PL406989A priority Critical patent/PL406989A1/en
Priority to PCT/PL2015/000010 priority patent/WO2015115923A2/en
Publication of PL406989A1 publication Critical patent/PL406989A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA

Abstract

Przedmiotem wynalazku jest metoda predykcyjna do wykrywania i/lub wykluczenia raka płuca polegająca na pomiarze poziomu ekspresji miRNA w próbce badanej, która zawiera: - detekcję w biologicznej próbce przynajmniej 3 miRNA zawartych na liście 24 miRNA, oraz określenie ilości wskazanych miRNA w odniesieniu do próby kontrolnej. Ponadto wynalazek obejmuje zastosowanie tej metody do wykrywania raka płuca u osób z grupy wysokiego ryzyka zachorowania na raka płuca.The subject of the invention is a predictive method for detection and / or exclusion of lung cancer consisting in measuring the level of miRNA expression in a test sample, which includes: - detection in a biological sample of at least 3 miRNAs contained in the list of 24 miRNAs, and determination of the amount of miRNAs indicated in relation to the control sample . In addition, the invention encompasses the use of this method for detecting lung cancer in persons at high risk of developing lung cancer.

PL406989A 2014-01-29 2014-01-29 Profile of micro RNA in blood as the test for detecting lung cancer PL406989A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
PL406989A PL406989A1 (en) 2014-01-29 2014-01-29 Profile of micro RNA in blood as the test for detecting lung cancer
PCT/PL2015/000010 WO2015115923A2 (en) 2014-01-29 2015-01-29 A profile of microrna in the blood as a test for the detection of lung cancer

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL406989A PL406989A1 (en) 2014-01-29 2014-01-29 Profile of micro RNA in blood as the test for detecting lung cancer

Publications (1)

Publication Number Publication Date
PL406989A1 true PL406989A1 (en) 2015-08-03

Family

ID=52697507

Family Applications (1)

Application Number Title Priority Date Filing Date
PL406989A PL406989A1 (en) 2014-01-29 2014-01-29 Profile of micro RNA in blood as the test for detecting lung cancer

Country Status (2)

Country Link
PL (1) PL406989A1 (en)
WO (1) WO2015115923A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6991433B2 (en) 2014-06-18 2022-01-12 東レ株式会社 Lung cancer detection kit or device and detection method
JPWO2017221744A1 (en) * 2016-06-24 2019-04-18 国立大学法人名古屋大学 Method for providing information for lung cancer test, method for testing lung cancer, lung cancer testing device, program and recording medium for lung cancer testing device, and kit for miRNA measurement for lung cancer testing
US11634778B2 (en) 2017-06-29 2023-04-25 Toray Industries, Inc. Kit, device, and method for detecting lung cancer

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2336353A1 (en) 2009-12-17 2011-06-22 febit holding GmbH miRNA fingerprints in the diagnosis of diseases
EP2505663A1 (en) 2011-03-30 2012-10-03 IFOM Fondazione Istituto Firc di Oncologia Molecolare A method to identify asymptomatic high-risk individuals with early stage lung cancer by means of detecting miRNAs in biologic fluids

Also Published As

Publication number Publication date
WO2015115923A2 (en) 2015-08-06
WO2015115923A3 (en) 2015-10-01

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