PL404174A1 - Zastosowanie pochodnych aminowych jako inhibitorów aktywności interleukiny 15 - Google Patents

Zastosowanie pochodnych aminowych jako inhibitorów aktywności interleukiny 15

Info

Publication number
PL404174A1
PL404174A1 PL404174A PL40417413A PL404174A1 PL 404174 A1 PL404174 A1 PL 404174A1 PL 404174 A PL404174 A PL 404174A PL 40417413 A PL40417413 A PL 40417413A PL 404174 A1 PL404174 A1 PL 404174A1
Authority
PL
Poland
Prior art keywords
inhibitors
amine derivatives
interleukin activity
interleukin
activity
Prior art date
Application number
PL404174A
Other languages
English (en)
Inventor
Katarzyna Koziak
Barbara Żyżyńska-Granica
Sławomir Filipek
Szymon Niewieczerzał
Bartosz Trzaskowski
Oliwia Zegrocka-Stendel
Małgorzata Dutkiewicz
Piotr Krzeczyński
Elżbieta Kaczmarek
Magdalena Winiarska
Original Assignee
Warszawski Uniwersytet Medyczny
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warszawski Uniwersytet Medyczny filed Critical Warszawski Uniwersytet Medyczny
Priority to PL404174A priority Critical patent/PL404174A1/pl
Priority to PCT/IB2014/000896 priority patent/WO2014191823A1/en
Publication of PL404174A1 publication Critical patent/PL404174A1/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4172—Imidazole-alkanecarboxylic acids, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/417—Imidazole-alkylamines, e.g. histamine, phentolamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Abstract

Wynalazek dotyczy zastosowania związków o wzorach ogólnych (I) lub (II) oraz ich tautomerów, izomerów, farmaceutycznie dopuszczalnych soli i solwatów, do zapobiegania i leczenia chorób, u podłoża których jest nadprodukcja interleukiny 15, takich jak reumatoidalne zapalenie stawów.
PL404174A 2013-05-31 2013-05-31 Zastosowanie pochodnych aminowych jako inhibitorów aktywności interleukiny 15 PL404174A1 (pl)

Priority Applications (2)

Application Number Priority Date Filing Date Title
PL404174A PL404174A1 (pl) 2013-05-31 2013-05-31 Zastosowanie pochodnych aminowych jako inhibitorów aktywności interleukiny 15
PCT/IB2014/000896 WO2014191823A1 (en) 2013-05-31 2014-05-29 Amine derivatives as il-15 activity inhibitors

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL404174A PL404174A1 (pl) 2013-05-31 2013-05-31 Zastosowanie pochodnych aminowych jako inhibitorów aktywności interleukiny 15

Publications (1)

Publication Number Publication Date
PL404174A1 true PL404174A1 (pl) 2014-12-08

Family

ID=51176400

Family Applications (1)

Application Number Title Priority Date Filing Date
PL404174A PL404174A1 (pl) 2013-05-31 2013-05-31 Zastosowanie pochodnych aminowych jako inhibitorów aktywności interleukiny 15

Country Status (2)

Country Link
PL (1) PL404174A1 (pl)
WO (1) WO2014191823A1 (pl)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11278505B2 (en) 2017-04-24 2022-03-22 University Of Massachusetts Diagnosis and treatment of vitiligo

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07500580A (ja) * 1991-09-09 1995-01-19 ペプテック　リミテッド 糖尿病の合併症及び病因の処理方法
DE4328871A1 (de) * 1993-08-27 1995-03-02 Beiersdorf Ag Mittel gegen empfindliche, hyperreaktive Hautzustände, atopische Dermatiden, Pruritus, Psoriasis Prurigo, Photodermatosen und Ichthyosis
JP4989841B2 (ja) * 2003-10-16 2012-08-01 株式会社優芳舞 血管新生阻害剤、血管新生を伴う疾患の治療剤または予防剤
CU23472A1 (es) 2004-09-17 2009-12-17 Ct Ingenieria Genetica Biotech Péptido antagonista de la interleucina-15
JP2008031066A (ja) * 2006-07-27 2008-02-14 Inter Cyto Nano Science Co Ltd 脱顆粒反応抑制剤
CU23716A1 (es) 2008-09-30 2011-10-05 Ct Ingenieria Genetica Biotech Péptido antagonista de la actividad de la interleucina-15

Also Published As

Publication number Publication date
WO2014191823A1 (en) 2014-12-04

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