PL3989962T3 - Terapia skojarzona acetyloleucyną i miglustatem w leczeniu lizosomalnej choroby spichrzeniowej - Google Patents
Terapia skojarzona acetyloleucyną i miglustatem w leczeniu lizosomalnej choroby spichrzeniowejInfo
- Publication number
- PL3989962T3 PL3989962T3 PL20736444.9T PL20736444T PL3989962T3 PL 3989962 T3 PL3989962 T3 PL 3989962T3 PL 20736444 T PL20736444 T PL 20736444T PL 3989962 T3 PL3989962 T3 PL 3989962T3
- Authority
- PL
- Poland
- Prior art keywords
- miglustat
- leucine
- acetyl
- treating
- combination therapy
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962868383P | 2019-06-28 | 2019-06-28 | |
| US201962931003P | 2019-11-05 | 2019-11-05 | |
| PCT/IB2020/056096 WO2020261230A1 (en) | 2019-06-28 | 2020-06-26 | Combination therapy with acetyl-leucine and miglustat |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3989962T3 true PL3989962T3 (pl) | 2025-11-17 |
Family
ID=71452519
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL20736444.9T PL3989962T3 (pl) | 2019-06-28 | 2020-06-26 | Terapia skojarzona acetyloleucyną i miglustatem w leczeniu lizosomalnej choroby spichrzeniowej |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20220362189A1 (pl) |
| EP (2) | EP4650003A2 (pl) |
| DK (1) | DK3989962T3 (pl) |
| ES (1) | ES3048174T3 (pl) |
| FI (1) | FI3989962T3 (pl) |
| HR (1) | HRP20251256T1 (pl) |
| LT (1) | LT3989962T (pl) |
| MA (1) | MA56386B1 (pl) |
| PL (1) | PL3989962T3 (pl) |
| PT (1) | PT3989962T (pl) |
| RS (1) | RS67283B1 (pl) |
| SI (1) | SI3989962T1 (pl) |
| SM (1) | SMT202500369T1 (pl) |
| WO (1) | WO2020261230A1 (pl) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201709459D0 (en) | 2017-06-14 | 2017-07-26 | Intrabio Ltd | Treatment for migraine |
| JP7471298B2 (ja) | 2018-12-06 | 2024-04-19 | イントラビオ エルティーディー | アセチル-ロイシンの重水素化類似体 |
| CN118409027B (zh) * | 2024-07-02 | 2024-09-10 | 成都市食品检验研究院 | 一种食品中1-脱氧野尻霉素的含量检测方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3103469B1 (en) | 2010-06-25 | 2020-12-09 | Shire Human Genetic Therapies, Inc. | Cns delivery of therapeutic agents |
| MA43876B1 (fr) | 2016-08-11 | 2019-04-30 | Intrabio Ltd | Compositions pharmaceutiques et leur utilisations contre les maladies de surcharge lysosomale |
-
2020
- 2020-06-26 PL PL20736444.9T patent/PL3989962T3/pl unknown
- 2020-06-26 ES ES20736444T patent/ES3048174T3/es active Active
- 2020-06-26 EP EP25193150.7A patent/EP4650003A2/en active Pending
- 2020-06-26 MA MA56386A patent/MA56386B1/fr unknown
- 2020-06-26 EP EP20736444.9A patent/EP3989962B1/en active Active
- 2020-06-26 DK DK20736444.9T patent/DK3989962T3/da active
- 2020-06-26 SM SM20250369T patent/SMT202500369T1/it unknown
- 2020-06-26 PT PT207364449T patent/PT3989962T/pt unknown
- 2020-06-26 FI FIEP20736444.9T patent/FI3989962T3/fi active
- 2020-06-26 LT LTEPPCT/IB2020/056096T patent/LT3989962T/lt unknown
- 2020-06-26 US US17/623,313 patent/US20220362189A1/en active Pending
- 2020-06-26 SI SI202030669T patent/SI3989962T1/sl unknown
- 2020-06-26 HR HRP20251256TT patent/HRP20251256T1/hr unknown
- 2020-06-26 RS RS20251006A patent/RS67283B1/sr unknown
- 2020-06-26 WO PCT/IB2020/056096 patent/WO2020261230A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| MA56386B1 (fr) | 2025-10-31 |
| HRP20251256T1 (hr) | 2025-12-05 |
| ES3048174T3 (en) | 2025-12-09 |
| EP3989962A1 (en) | 2022-05-04 |
| EP3989962B1 (en) | 2025-08-27 |
| EP4650003A2 (en) | 2025-11-19 |
| SMT202500369T1 (it) | 2025-11-10 |
| LT3989962T (lt) | 2025-10-10 |
| SI3989962T1 (sl) | 2025-11-28 |
| PT3989962T (pt) | 2025-10-09 |
| DK3989962T3 (da) | 2025-10-13 |
| WO2020261230A1 (en) | 2020-12-30 |
| RS67283B1 (sr) | 2025-11-28 |
| MA56386A (fr) | 2022-05-04 |
| US20220362189A1 (en) | 2022-11-17 |
| FI3989962T3 (fi) | 2025-10-08 |
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