PL3962942T3 - Preparat przeciwciała anty-il-6 - Google Patents

Preparat przeciwciała anty-il-6

Info

Publication number
PL3962942T3
PL3962942T3 PL20728590.9T PL20728590T PL3962942T3 PL 3962942 T3 PL3962942 T3 PL 3962942T3 PL 20728590 T PL20728590 T PL 20728590T PL 3962942 T3 PL3962942 T3 PL 3962942T3
Authority
PL
Poland
Prior art keywords
antibody preparation
antibody
preparation
Prior art date
Application number
PL20728590.9T
Other languages
English (en)
Inventor
Gaozhong Zhu
Zahra Shahrokh
Mark Melville
Madhav N. Devalaraja
Original Assignee
Novo Nordisk A/S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk A/S filed Critical Novo Nordisk A/S
Publication of PL3962942T3 publication Critical patent/PL3962942T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • C07K16/248—IL-6
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
PL20728590.9T 2019-05-01 2020-04-30 Preparat przeciwciała anty-il-6 PL3962942T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962841662P 2019-05-01 2019-05-01
EP19181345 2019-06-19
PCT/US2020/030865 WO2020223565A1 (en) 2019-05-01 2020-04-30 Anti-il-6 antibody formulation

Publications (1)

Publication Number Publication Date
PL3962942T3 true PL3962942T3 (pl) 2026-02-16

Family

ID=70857238

Family Applications (1)

Application Number Title Priority Date Filing Date
PL20728590.9T PL3962942T3 (pl) 2019-05-01 2020-04-30 Preparat przeciwciała anty-il-6

Country Status (8)

Country Link
EP (3) EP4591885A3 (pl)
JP (3) JP7701273B2 (pl)
ES (1) ES3055418T3 (pl)
HR (1) HRP20251529T1 (pl)
MA (1) MA55809B1 (pl)
PL (1) PL3962942T3 (pl)
RS (1) RS67540B1 (pl)
WO (1) WO2020223565A1 (pl)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102735988B1 (ko) 2019-02-18 2024-12-03 일라이 릴리 앤드 캄파니 치료 항체 제제

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5856135A (en) 1993-05-31 1999-01-05 Chugai Seiyaku Kabushiki Kaisha Reshaped human antibody to human interleukin-6
PT1355919E (pt) 2000-12-12 2011-03-02 Medimmune Llc Moléculas com semivida longa, composições que as contêm e suas utilizações
BRPI0214168B8 (pt) 2001-11-14 2021-05-25 Centocor Inc anticorpos anti-il-6, moléculas de ácido nucleico codificando os mesmos, vetores compreendendo as referidas moléculas, composições e formulações compreendendo os referidos anticorpos, bem como métodos de produção dos mesmos
JP4463104B2 (ja) 2002-08-30 2010-05-12 財団法人化学及血清療法研究所 ヒト抗ヒトインターロイキン−６抗体及び該抗体フラグメント
PE20061324A1 (es) 2005-04-29 2007-01-15 Centocor Inc Anticuerpos anti-il-6, composiciones, metodos y usos
ES2852423T3 (es) 2005-05-20 2021-09-13 Ablynx Nv NanobodiesTM mejorados para el tratamiento de trastornos mediados por agregación
TW200806317A (en) * 2006-03-20 2008-02-01 Wyeth Corp Methods for reducing protein aggregation
TW200831528A (en) 2006-11-30 2008-08-01 Astrazeneca Ab Compounds
CN104119438A (zh) 2009-01-29 2014-10-29 米迪缪尼有限公司 延长体内半衰期的人抗il-6抗体及其在治疗肿瘤、自身免疫性疾病和炎症性疾病中的应用
EP2399604A1 (en) * 2010-06-25 2011-12-28 F. Hoffmann-La Roche AG Novel antibody formulation
US9592297B2 (en) * 2012-08-31 2017-03-14 Bayer Healthcare Llc Antibody and protein formulations
US20150239970A1 (en) * 2012-10-25 2015-08-27 Medimmune, Llc Stable, Low Viscosity Antibody Formulation
CN108026582A (zh) 2015-07-31 2018-05-11 米迪缪尼有限公司 用于治疗海帕西啶介导的病症的方法
EP3419599A4 (en) * 2016-02-23 2019-09-11 Sesen Bio, Inc. IL-6 ANTAGONIST FORMULATIONS AND USE THEREOF
KR20200012823A (ko) 2017-02-01 2020-02-05 예일 유니버시티 이뇨제 내성의 치료
CA3087699A1 (en) 2018-01-05 2019-07-11 Corvidia Therapeutics, Inc. Methods for treating il-6 mediated inflammation without immunosuppression

Also Published As

Publication number Publication date
JP2025114623A (ja) 2025-08-05
ES3055418T3 (en) 2026-02-11
JP2022531331A (ja) 2022-07-06
EP4631523A3 (en) 2025-12-31
MA55809A (fr) 2022-03-09
EP3962942A1 (en) 2022-03-09
HRP20251529T1 (hr) 2026-01-16
EP3962942B1 (en) 2025-10-22
WO2020223565A1 (en) 2020-11-05
EP3962942C0 (en) 2025-10-22
EP4591885A3 (en) 2025-11-19
JP2025166156A (ja) 2025-11-05
JP7701273B2 (ja) 2025-07-01
JP7755766B2 (ja) 2025-10-16
MA55809B1 (fr) 2025-12-31
RS67540B1 (sr) 2026-01-30
EP4631523A2 (en) 2025-10-15
EP4591885A2 (en) 2025-07-30

Similar Documents

Publication Publication Date Title
KR102763158B9 (ko) 최적화된 항tl1a 항체
IL289354A (en) Anti-cd154 antibodies and uses thereof
EP3822289A4 (en) ANTI-SIRP-ALPHA ANTIBODIES
EP3797122A4 (en) Anti-ror antibody constructs
EP3794041C0 (en) ANTI-MUC1 ANTIBODIES
MA52212A (fr) Anticorps multivalent
EP3849598A4 (en) Anti-trem-2 agonist antibodies
EP3941944A4 (en) Claudin-6 bispecific antibodies
PL3449940T3 (pl) Preparat zawierający przeciwciała
EP3589648A4 (en) MONOCLONAL ANTI-RSV ANTIBODY FORMULATION
IL281717A (en) Antibody formulation
EP3763743A4 (en) BISPECIFIC ANTIBODY
EP4081547A4 (en) Novel anti-fgfr2b antibodies
CR20230573A (es) ANTICUERPOS ANTI-SIRP-alfa
EP3806903A4 (en) CD79A CHIMERIC ANTIGEN RECEPTORS
DK4214240T3 (da) Anti-ccr8-antistoffer
HUE061610T2 (hu) Készítmény
IL282813A (en) Antibody formulation
IL289252A (en) Ep2 antagonist
EP3615678C0 (en) ANTIBODY SELECTION METHOD
IL281976A (en) Anti-fgfr2 antibody formulations
EP4081539A4 (en) Novel anti-fgfr2b antibodies
IL286024A (en) Stabilized formulations containing anti-il-33 antibodies
IL283886A (en) Antibody formulations
EP3888678A4 (en) Anti-pd-l1 antibody preparation