PL395778A1 - The method of dividing droplets into a task in a microfluidic connector - Google Patents

The method of dividing droplets into a task in a microfluidic connector

Info

Publication number
PL395778A1
PL395778A1 PL395778A PL39577811A PL395778A1 PL 395778 A1 PL395778 A1 PL 395778A1 PL 395778 A PL395778 A PL 395778A PL 39577811 A PL39577811 A PL 39577811A PL 395778 A1 PL395778 A1 PL 395778A1
Authority
PL
Poland
Prior art keywords
channel
discharge
drops
discharge channel
continuous liquid
Prior art date
Application number
PL395778A
Other languages
Polish (pl)
Inventor
Slawomir Jakiela
Tomasz Kamiński
Krzysztof Churski
Piotr Garstecki
Original Assignee
Instytut Chemii Fizycznej Polskiej Akademii Nauk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Instytut Chemii Fizycznej Polskiej Akademii Nauk filed Critical Instytut Chemii Fizycznej Polskiej Akademii Nauk
Priority to PL395778A priority Critical patent/PL395778A1/en
Priority to CH8342012A priority patent/CH705287B1/en
Publication of PL395778A1 publication Critical patent/PL395778A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/02—Form or structure of the vessel
    • C12M23/16—Microfluidic devices; Capillary tubes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502769—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements
    • B01L3/502784—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for droplet or plug flow, e.g. digital microfluidics
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0694—Creating chemical gradients in a fluid
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0864—Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics

Abstract

Dividing drops at a microfluidic junction comprising a supply channel, a first discharge channel having an additional channel, and a second discharge channel, comprises (a) supplying the drops to the microfluidic junction through the supply channel (2) by flowing continuous liquid through the channel, the first discharge channel (5) and the second discharge channel (6), and (b) controlling the ratio of the flow rates in the discharge channels by pumping or aspirating the continuous liquid through the additional channel (9). Dividing drops at a microfluidic junction comprising a supply channel, a first discharge channel having an additional channel, and a second discharge channel, comprises (a) supplying the drops to the microfluidic junction through the supply channel (2) by flowing continuous liquid through the channel, the first discharge channel (5) and the second discharge channel (6), and (b) controlling the ratio of the flow rates in the discharge channels by pumping or aspirating the continuous liquid through the additional channel (9), at least until the time point, when the portion of the drops present in the first discharge channel (5) separates from the portion of the drops present in the second discharge channel.
PL395778A 2011-07-27 2011-07-27 The method of dividing droplets into a task in a microfluidic connector PL395778A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
PL395778A PL395778A1 (en) 2011-07-27 2011-07-27 The method of dividing droplets into a task in a microfluidic connector
CH8342012A CH705287B1 (en) 2011-07-27 2012-06-14 Method of dividing drops at a microfluidic junction.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL395778A PL395778A1 (en) 2011-07-27 2011-07-27 The method of dividing droplets into a task in a microfluidic connector

Publications (1)

Publication Number Publication Date
PL395778A1 true PL395778A1 (en) 2013-02-04

Family

ID=47601937

Family Applications (1)

Application Number Title Priority Date Filing Date
PL395778A PL395778A1 (en) 2011-07-27 2011-07-27 The method of dividing droplets into a task in a microfluidic connector

Country Status (2)

Country Link
CH (1) CH705287B1 (en)
PL (1) PL395778A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10209246B2 (en) 2012-06-26 2019-02-19 Curiosity Diagnostics Sp. Z.O.O. Method for performing quantitation assays

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020072303A1 (en) 2018-10-03 2020-04-09 Verily Life Sciences Llc Systems and methods for maintaining constant volumetric flow rates in a fluid channel

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10209246B2 (en) 2012-06-26 2019-02-19 Curiosity Diagnostics Sp. Z.O.O. Method for performing quantitation assays

Also Published As

Publication number Publication date
CH705287A2 (en) 2013-01-31
CH705287B1 (en) 2013-12-13

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