PL3956663T3 - Sposób profilowania metabolizmu energetycznego populacji komórek - Google Patents

Sposób profilowania metabolizmu energetycznego populacji komórek

Info

Publication number
PL3956663T3
PL3956663T3 PL20716858.4T PL20716858T PL3956663T3 PL 3956663 T3 PL3956663 T3 PL 3956663T3 PL 20716858 T PL20716858 T PL 20716858T PL 3956663 T3 PL3956663 T3 PL 3956663T3
Authority
PL
Poland
Prior art keywords
profiling
population
cells
energetic metabolism
energetic
Prior art date
Application number
PL20716858.4T
Other languages
English (en)
Inventor
Rafael ARGÜELLO
Philippe Pierre
Alexis COMBES
Original Assignee
Institut National De La Santé Et De La Recherche Médicale (Inserm)
Centre National De La Recherche Scientifique (Cnrs)
Université D'aix Marseille
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Institut National De La Santé Et De La Recherche Médicale (Inserm), Centre National De La Recherche Scientifique (Cnrs), Université D'aix Marseille filed Critical Institut National De La Santé Et De La Recherche Médicale (Inserm)
Publication of PL3956663T3 publication Critical patent/PL3956663T3/pl

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • G01N33/5023—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects on expression patterns
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • G01N33/5038—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects involving detection of metabolites per se
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5091—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Physiology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
PL20716858.4T 2019-04-15 2020-04-14 Sposób profilowania metabolizmu energetycznego populacji komórek PL3956663T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP19305485 2019-04-15
PCT/EP2020/060486 WO2020212362A1 (en) 2019-04-15 2020-04-14 A method of profiling the energetic metabolism of a population of cells

Publications (1)

Publication Number Publication Date
PL3956663T3 true PL3956663T3 (pl) 2025-10-20

Family

ID=66397184

Family Applications (1)

Application Number Title Priority Date Filing Date
PL20716858.4T PL3956663T3 (pl) 2019-04-15 2020-04-14 Sposób profilowania metabolizmu energetycznego populacji komórek

Country Status (8)

Country Link
US (1) US20220244245A1 (pl)
EP (1) EP3956663B1 (pl)
JP (1) JP7518853B2 (pl)
KR (1) KR20210151842A (pl)
CN (1) CN113677992B (pl)
ES (1) ES3026136T3 (pl)
PL (1) PL3956663T3 (pl)
WO (1) WO2020212362A1 (pl)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116183788A (zh) * 2023-01-09 2023-05-30 中国农业大学 一种基于同位素示踪技术结合高分辨质谱的精准代谢流分析tca循环的方法
CN117116346B (zh) * 2023-05-22 2025-05-30 中山大学 一种基于单细胞分析建立的用于评估头颈鳞癌预后的评分系统
EP4530629A1 (en) * 2023-09-26 2025-04-02 Université de Bordeaux Ex vivo method for predicting the response to an immunotherapy treatment of hepatocellular carcinoma in a subject

Family Cites Families (22)

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Publication number Priority date Publication date Assignee Title
US4774339A (en) 1987-08-10 1988-09-27 Molecular Probes, Inc. Chemically reactive dipyrrometheneboron difluoride dyes
US5132432A (en) 1989-09-22 1992-07-21 Molecular Probes, Inc. Chemically reactive pyrenyloxy sulfonic acid dyes
US5274113A (en) 1991-11-01 1993-12-28 Molecular Probes, Inc. Long wavelength chemically reactive dipyrrometheneboron difluoride dyes and conjugates
US5433896A (en) 1994-05-20 1995-07-18 Molecular Probes, Inc. Dibenzopyrrometheneboron difluoride dyes
US5248782A (en) 1990-12-18 1993-09-28 Molecular Probes, Inc. Long wavelength heteroaryl-substituted dipyrrometheneboron difluoride dyes
US5338854A (en) 1991-02-13 1994-08-16 Molecular Probes, Inc. Fluorescent fatty acids derived from dipyrrometheneboron difluoride dyes
US5187288A (en) 1991-05-22 1993-02-16 Molecular Probes, Inc. Ethenyl-substituted dipyrrometheneboron difluoride dyes and their synthesis
US5800996A (en) 1996-05-03 1998-09-01 The Perkin Elmer Corporation Energy transfer dyes with enchanced fluorescence
US5696157A (en) 1996-11-15 1997-12-09 Molecular Probes, Inc. Sulfonated derivatives of 7-aminocoumarin
US5830912A (en) 1996-11-15 1998-11-03 Molecular Probes, Inc. Derivatives of 6,8-difluoro-7-hydroxycoumarin
US5866366A (en) 1997-07-01 1999-02-02 Smithkline Beecham Corporation gidB
US6130101A (en) 1997-09-23 2000-10-10 Molecular Probes, Inc. Sulfonated xanthene derivatives
US5962244A (en) * 1998-05-07 1999-10-05 Tularik Inc. High-throughput in vitro assays for modulators of peptidyl transferase
JP2003513920A (ja) * 1999-11-12 2003-04-15 ザ ジョンズ ホプキンス ユニバーシティー スクール オブ メディシン 細胞内マロニルＣｏＡレベルの増加による癌の治療
CA2417816A1 (en) 2000-08-04 2002-02-14 Molecular Probes, Inc. Derivatives of 1,2-dihydro-7-hydroxyquinolines containing fused rings
US20070087401A1 (en) * 2003-10-17 2007-04-19 Andy Neilson Analysis of metabolic activity in cells using extracellular flux rate measurements
US20060057069A1 (en) * 2004-06-07 2006-03-16 California Institute Of Technology Detection of protein expression in vivo using fluorescent puromycin conjugates
FR2936528A1 (fr) * 2008-09-26 2010-04-02 Centre Nat Rech Scient Nouvelle methode de mesure non-radioactive de la synthese proteique et marquage des proteines dans les cellules vivantes
EP2620142A1 (en) * 2012-01-27 2013-07-31 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Hedgehog signaling pathway involved in energy metabolism
EP3274713B1 (en) * 2015-03-27 2020-02-19 Agilent Technologies, Inc. Method and system for determining integrated metabolic baseline and potential of living cells
EP3426766B1 (en) * 2016-03-08 2022-12-28 Yissum Research and Development Company of the Hebrew University of Jerusalem Ltd. Method for continuous biosensing
JP2018008914A (ja) * 2016-07-15 2018-01-18 国立大学法人金沢大学 抗脳腫瘍剤及び脳腫瘍治療用医薬組成物

Also Published As

Publication number Publication date
WO2020212362A1 (en) 2020-10-22
US20220244245A1 (en) 2022-08-04
EP3956663A1 (en) 2022-02-23
ES3026136T3 (en) 2025-06-10
EP3956663C0 (en) 2025-02-12
CN113677992A (zh) 2021-11-19
CN113677992B (zh) 2024-08-09
EP3956663B1 (en) 2025-02-12
JP2022528908A (ja) 2022-06-16
JP7518853B2 (ja) 2024-07-18
KR20210151842A (ko) 2021-12-14

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