PL386351A1 - Sposób wytwarzania polianionowych koniugatów lek-nośnik - Google Patents

Sposób wytwarzania polianionowych koniugatów lek-nośnik

Info

Publication number
PL386351A1
PL386351A1 PL386351A PL38635108A PL386351A1 PL 386351 A1 PL386351 A1 PL 386351A1 PL 386351 A PL386351 A PL 386351A PL 38635108 A PL38635108 A PL 38635108A PL 386351 A1 PL386351 A1 PL 386351A1
Authority
PL
Poland
Prior art keywords
manufacturing
drug carrier
polyanion
conjugates
polyanion conjugates
Prior art date
Application number
PL386351A
Other languages
English (en)
Other versions
PL227543B1 (pl
Inventor
Janusz Boratyński
Mohamed Salah Omar Megahed
Urszula Kańska
Dmitry Nevozhay
Joanna Wietrzyk
Original Assignee
Instytut Immunologii i Terapii Doświadczalnej PAN
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Instytut Immunologii i Terapii Doświadczalnej PAN filed Critical Instytut Immunologii i Terapii Doświadczalnej PAN
Priority to PL386351A priority Critical patent/PL227543B1/pl
Priority to PCT/PL2009/050031 priority patent/WO2010047607A2/en
Priority to EP09760347.6A priority patent/EP2337586B1/en
Priority to US13/121,295 priority patent/US8623998B2/en
Publication of PL386351A1 publication Critical patent/PL386351A1/pl
Publication of PL227543B1 publication Critical patent/PL227543B1/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/6435—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the peptide or protein in the drug conjugate being a connective tissue peptide, e.g. collagen, fibronectin or gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/643—Albumins, e.g. HSA, BSA, ovalbumin or a Keyhole Limpet Hemocyanin [KHL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Polyamides (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PL386351A 2008-10-26 2008-10-26 Sposób wytwarzania koniugatu fibrynogenu glikowanego glukozą z metotreksatem PL227543B1 (pl)

Priority Applications (4)

Application Number Priority Date Filing Date Title
PL386351A PL227543B1 (pl) 2008-10-26 2008-10-26 Sposób wytwarzania koniugatu fibrynogenu glikowanego glukozą z metotreksatem
PCT/PL2009/050031 WO2010047607A2 (en) 2008-10-26 2009-10-23 Method of production of polyanionic drug-carrier conjugates
EP09760347.6A EP2337586B1 (en) 2008-10-26 2009-10-23 Methotrexate-fibrinogen conjugate
US13/121,295 US8623998B2 (en) 2008-10-26 2009-10-23 Method of production of polyanionic drug-carrier conjugates

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL386351A PL227543B1 (pl) 2008-10-26 2008-10-26 Sposób wytwarzania koniugatu fibrynogenu glikowanego glukozą z metotreksatem

Publications (2)

Publication Number Publication Date
PL386351A1 true PL386351A1 (pl) 2010-05-10
PL227543B1 PL227543B1 (pl) 2017-12-29

Family

ID=42060572

Family Applications (1)

Application Number Title Priority Date Filing Date
PL386351A PL227543B1 (pl) 2008-10-26 2008-10-26 Sposób wytwarzania koniugatu fibrynogenu glikowanego glukozą z metotreksatem

Country Status (4)

Country Link
US (1) US8623998B2 (pl)
EP (1) EP2337586B1 (pl)
PL (1) PL227543B1 (pl)
WO (1) WO2010047607A2 (pl)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2604761A1 (de) 1976-02-07 1977-08-11 Bayer Ag Acylierte imidazolyl-o,n-acetale, verfahren zu ihrer herstellung und ihre verwendung als fungizide
PL198235A1 (pl) 1977-05-18 1978-11-20 Inst Przemyslu Skorzanego Tworzywo sztuczne do regeneracji i wytwarzania klocow do wycinarek materialow wierzchnich obuwia
PL130458B1 (en) 1981-02-20 1984-08-31 Polska Akademia Nauk Instytut Process for preparing novel conjugates of 4-amino-n 10 downwards methyl-ptercyl-glutamic acid with albumen
AU2003287110A1 (en) 2002-12-10 2004-06-30 Janusz Borantynski Coupling of dicarboxylic compounds by convertion into anhdrids
PL195813B1 (pl) * 2002-12-10 2007-10-31 Inst Immunologii I Terapii Dos Sposób modyfikacji cząsteczki chemicznej

Also Published As

Publication number Publication date
EP2337586B1 (en) 2015-01-21
EP2337586A2 (en) 2011-06-29
US8623998B2 (en) 2014-01-07
WO2010047607A3 (en) 2010-07-22
WO2010047607A2 (en) 2010-04-29
PL227543B1 (pl) 2017-12-29
US20110245466A1 (en) 2011-10-06

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