PL3861946T3 - Kaniula do przezskórnej małoinwazyjnej kaniulacji żyły głównej - Google Patents

Kaniula do przezskórnej małoinwazyjnej kaniulacji żyły głównej

Info

Publication number
PL3861946T3
PL3861946T3 PL20177271.2T PL20177271T PL3861946T3 PL 3861946 T3 PL3861946 T3 PL 3861946T3 PL 20177271 T PL20177271 T PL 20177271T PL 3861946 T3 PL3861946 T3 PL 3861946T3
Authority
PL
Poland
Prior art keywords
cannula
minimally invasive
vena cava
percutaneous minimally
cannulation
Prior art date
Application number
PL20177271.2T
Other languages
English (en)
Inventor
Sanjeev Choudhary
Piotr Suwalski
Marta Makuch
Jacek Olszewski
Original Assignee
Medinice S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medinice S.A. filed Critical Medinice S.A.
Publication of PL3861946T3 publication Critical patent/PL3861946T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0021—Catheters; Hollow probes characterised by the form of the tubing
    • A61M25/0023—Catheters; Hollow probes characterised by the form of the tubing by the form of the lumen, e.g. cross-section, variable diameter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/34—Trocars; Puncturing needles
    • A61B17/3417—Details of tips or shafts, e.g. grooves, expandable, bendable; Multiple coaxial sliding cannulas, e.g. for dilating
    • A61B17/3421—Cannulas
    • A61B17/3423—Access ports, e.g. toroid shape introducers for instruments or hands
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621—Extra-corporeal blood circuits
    • A61M1/3653—Interfaces between patient blood circulation and extra-corporal blood circuit
    • A61M1/3659—Cannulae pertaining to extracorporeal circulation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/34—Trocars; Puncturing needles
    • A61B17/3417—Details of tips or shafts, e.g. grooves, expandable, bendable; Multiple coaxial sliding cannulas, e.g. for dilating
    • A61B17/3421—Cannulas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/00234—Surgical instruments, devices or methods, e.g. tourniquets for minimally invasive surgery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/34—Trocars; Puncturing needles
    • A61B17/3478—Endoscopic needles, e.g. for infusion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621—Extra-corporeal blood circuits
    • A61M1/3666—Cardiac or cardiopulmonary bypass, e.g. heart-lung machines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0021—Catheters; Hollow probes characterised by the form of the tubing
    • A61M25/0041—Catheters; Hollow probes characterised by the form of the tubing pre-formed, e.g. specially adapted to fit with the anatomy of body channels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0043—Catheters; Hollow probes characterised by structural features
    • A61M25/005—Catheters; Hollow probes characterised by structural features with embedded materials for reinforcement, e.g. wires, coils, braids
    • A61M25/0052—Localized reinforcement, e.g. where only a specific part of the catheter is reinforced, for rapid exchange guidewire port
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0067—Catheters; Hollow probes characterised by the distal end, e.g. tips
    • A61M25/0068—Static characteristics of the catheter tip, e.g. shape, atraumatic tip, curved tip or tip structure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/10—Balloon catheters
    • A61M25/1002—Balloon catheters characterised by balloon shape
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12099—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder
    • A61B17/12109—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder in a blood vessel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12131—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
    • A61B17/12136—Balloons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/34—Trocars; Puncturing needles
    • A61B17/3494—Trocars; Puncturing needles with safety means for protection against accidental cutting or pricking, e.g. limiting insertion depth, pressure sensors
    • A61B17/3496—Protecting sleeves or inner probes; Retractable tips
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/00234—Surgical instruments, devices or methods, e.g. tourniquets for minimally invasive surgery
    • A61B2017/00238—Type of minimally invasive operation
    • A61B2017/00243—Type of minimally invasive operation cardiac
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/00234—Surgical instruments, devices or methods, e.g. tourniquets for minimally invasive surgery
    • A61B2017/00292—Surgical instruments, devices or methods, e.g. tourniquets for minimally invasive surgery mounted on or guided by flexible, e.g. catheter-like, means
    • A61B2017/003—Steerable
    • A61B2017/00318—Steering mechanisms
    • A61B2017/00331—Steering mechanisms with preformed bends
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
    • A61B2017/22051—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for with an inflatable part, e.g. balloon, for positioning, blocking, or immobilisation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/34—Trocars; Puncturing needles
    • A61B17/3417—Details of tips or shafts, e.g. grooves, expandable, bendable; Multiple coaxial sliding cannulas, e.g. for dilating
    • A61B17/3421—Cannulas
    • A61B17/3423—Access ports, e.g. toroid shape introducers for instruments or hands
    • A61B2017/3425—Access ports, e.g. toroid shape introducers for instruments or hands for internal organs, e.g. heart ports
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/34—Trocars; Puncturing needles
    • A61B17/3417—Details of tips or shafts, e.g. grooves, expandable, bendable; Multiple coaxial sliding cannulas, e.g. for dilating
    • A61B17/3421—Cannulas
    • A61B2017/3445—Cannulas used as instrument channel for multiple instruments
    • A61B2017/3447—Linked multiple cannulas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/34—Trocars; Puncturing needles
    • A61B2017/348—Means for supporting the trocar against the body or retaining the trocar inside the body
    • A61B2017/3482—Means for supporting the trocar against the body or retaining the trocar inside the body inside
    • A61B2017/3484—Anchoring means, e.g. spreading-out umbrella-like structure
    • A61B2017/3486—Balloon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/586—Ergonomic details therefor, e.g. specific ergonomics for left or right-handed users
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0067—Catheters; Hollow probes characterised by the distal end, e.g. tips
    • A61M25/0068—Static characteristics of the catheter tip, e.g. shape, atraumatic tip, curved tip or tip structure
    • A61M25/007—Side holes, e.g. their profiles or arrangements; Provisions to keep side holes unblocked
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
    • A61M25/02—Holding devices, e.g. on the body
    • A61M25/04—Holding devices, e.g. on the body in the body, e.g. expansible

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Surgery (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Vascular Medicine (AREA)
  • Pulmonology (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Cardiology (AREA)
  • Reproductive Health (AREA)
  • Child & Adolescent Psychology (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Surgical Instruments (AREA)
  • Materials For Medical Uses (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
PL20177271.2T 2020-05-28 2020-05-28 Kaniula do przezskórnej małoinwazyjnej kaniulacji żyły głównej PL3861946T3 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP20177271.2A EP3861946B1 (en) 2020-05-28 2020-05-28 Cannula for percutaneous minimally invasive cannulation of the vena cava

Publications (1)

Publication Number Publication Date
PL3861946T3 true PL3861946T3 (pl) 2023-09-04

Family

ID=71948410

Family Applications (1)

Application Number Title Priority Date Filing Date
PL20177271.2T PL3861946T3 (pl) 2020-05-28 2020-05-28 Kaniula do przezskórnej małoinwazyjnej kaniulacji żyły głównej

Country Status (9)

Country Link
US (1) US20210369301A1 (pl)
EP (1) EP3861946B1 (pl)
JP (1) JP7177516B2 (pl)
KR (1) KR102461525B1 (pl)
CN (1) CN113786549B (pl)
CA (1) CA3081942C (pl)
ES (1) ES2926596T3 (pl)
IL (1) IL275000B2 (pl)
PL (1) PL3861946T3 (pl)

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4140119A (en) * 1977-05-12 1979-02-20 Pollack Charles N Balloon-tipped extracorporeal cannula apparatus and method for insertion of same
US6866650B2 (en) * 1991-07-16 2005-03-15 Heartport, Inc. System for cardiac procedures
US5584803A (en) * 1991-07-16 1996-12-17 Heartport, Inc. System for cardiac procedures
JP2979804B2 (ja) * 1991-12-13 1999-11-15 株式会社ニッショー 大動脈閉塞バルーンカテーテル
US6048331A (en) 1996-05-14 2000-04-11 Embol-X, Inc. Cardioplegia occluder
US6168586B1 (en) 1998-08-07 2001-01-02 Embol-X, Inc. Inflatable cannula and method of using same
US6129713A (en) 1998-08-11 2000-10-10 Embol-X, Inc. Slidable cannula and method of use
US6440120B1 (en) * 1998-09-02 2002-08-27 Embol-X, Inc. Bendable shape-retaining cannula
US20060247575A1 (en) * 2001-12-21 2006-11-02 Richard Cartledge Balloon cannulae
GB0405426D0 (en) * 2004-03-11 2004-04-21 Jones Trevor Device and method for aorta occlusion during surgery on the heart or surrounding tissues
JP4790366B2 (ja) * 2005-10-13 2011-10-12 株式会社カネカ 体外循環用カテーテル
US9375217B2 (en) * 2006-07-18 2016-06-28 Boston Scientific Scimed, Inc. Catheterizing body lumens
US20090131867A1 (en) * 2007-11-16 2009-05-21 Liu Y King Steerable vertebroplasty system with cavity creation element
US20100249491A1 (en) * 2009-03-27 2010-09-30 Circulite, Inc. Two-piece transseptal cannula, delivery system, and method of delivery
US8795253B2 (en) * 2011-04-05 2014-08-05 Sorin Group Italia S.R.L. Bi-directional perfusion cannula
CN105899153A (zh) * 2013-09-27 2016-08-24 释放医疗股份有限公司 组织切开装置
CN204092788U (zh) * 2014-09-11 2015-01-14 南京大学医学院附属鼓楼医院 用于心脏再次手术的腔静脉插管
TWI789782B (zh) * 2014-09-17 2023-01-11 美商亞提歐醫藥公司 醫療系統
US20160361088A1 (en) * 2015-06-12 2016-12-15 Covidien Lp Catheter with pre-formed geometry for body lumen access
US10737008B2 (en) * 2015-08-17 2020-08-11 Abiomed, Inc. Dual lumen sheath for arterial access
CN208448389U (zh) * 2018-02-28 2019-02-01 昆明市延安医院 一种微创心脏手术改良型上腔静脉插管

Also Published As

Publication number Publication date
US20210369301A1 (en) 2021-12-02
CN113786549A (zh) 2021-12-14
IL275000B1 (en) 2023-10-01
ES2926596T3 (es) 2022-10-27
KR20210148540A (ko) 2021-12-08
KR102461525B1 (ko) 2022-11-01
CN113786549B (zh) 2024-04-12
IL275000A (en) 2021-12-01
CA3081942C (en) 2023-09-26
JP2021186251A (ja) 2021-12-13
EP3861946B1 (en) 2022-06-08
IL275000B2 (en) 2024-02-01
EP3861946A1 (en) 2021-08-11
CA3081942A1 (en) 2021-11-28
JP7177516B2 (ja) 2022-11-24

Similar Documents

Publication Publication Date Title
WO2018013536A3 (en) Multi-stage dilator and cannula system and method
PH12016502582A1 (en) TrK-INHIBITING COMPOUND
EP3405124C0 (en) MINIMAL INVASION TISSUE COLLECTION DEVICE
EP3672973A4 (en) HETEROCYCLIC COMPOUNDS USED AS KINASE INHIBITORS, COMPOSITIONS INCLUDING THE HETEROCYCLIC COMPOUND, AND METHODS OF USE THEREOF
EP3145419A4 (en) Cannula assembly kit, trocar assembly kit, sleeve assembly, minimally invasive surgery system and method therefor
WO2018155916A3 (ko) 피롤로-피리미딘 유도체 화합물, 이의 제조방법 및 이를 유효성분으로 함유하는 단백질 키나아제 관련 질환의 예방 또는 치료용 약학적 조성물
WO2012016186A8 (en) Macrocyclic kinase inhibitors and uses thereof
WO2012089828A3 (en) Heterocyclic compounds and their use as glycogen synthase kinase-3 inhibitors
WO2011093672A3 (en) Bicyclic heteroaryl derivatives having inhibitory activity for protein kinase
WO2013134336A3 (en) Inhibition of adaptor associated kinase 1 for the treatment of pain
WO2015148344A3 (en) Trka kinase inhibitors, compositions and methods thereof
EP3407802A4 (en) PERCUTANEOUS ARTERIAL ACCESS TO POSITIONING TRANSMYOKARD IMPLANT DEVICES AND METHOD
WO2011159840A3 (en) Phenylthioacetate compounds, compositions and methods of use
WO2017089390A8 (en) Janus kinases inhibitors, compositions thereof and use thereof
WO2008137622A3 (en) Aminopyrimidines useful as kinase inhibitors
WO2012048129A3 (en) Inhibitors of polo-like kinase
WO2012021778A3 (en) Methods for blocking cell proliferation and treating diseases and conditions responsive to cell growth inhibition
EP3378417C0 (en) MINIMALLY INVASIVE SURGERY DEVICE FOR BONE HARVESTING
EP2768548A4 (en) METHOD AND MECHANISMS FOR MINIMALLY INVASIVE IMPLANTATION OF HEART MEDICINE DEVICES WITH HEART CONTACT
EP3678578A4 (en) MINIMALLY INVASIVE ROBOTIC SURGERY SYSTEM
EP3658053A4 (en) MINIMALLY INVASIVE JOINT ASSEMBLY WITH ABLATION CAPABILITIES
EP3986303A4 (en) Insertable robot for minimally invasive surgery
WO2008128009A3 (en) Aminopyrimidines useful as kinase inhibitors
WO2016102672A3 (en) Inhibitors of akt kinase
WO2013185048A3 (en) Heterocyclic guanidine f1f0-atpase inhibitors