PL383819A1 - Enzym, esteraza lowastatyny, osadzony na nośniku nierozpuszczalnym w wodzie, sposób osadzania enzymu, zastosowanie enzymu, przepływowy reaktor biokatalityczny oraz sposób wytwarzania i/lub oczyszczania symwastatyny - Google Patents
Enzym, esteraza lowastatyny, osadzony na nośniku nierozpuszczalnym w wodzie, sposób osadzania enzymu, zastosowanie enzymu, przepływowy reaktor biokatalityczny oraz sposób wytwarzania i/lub oczyszczania symwastatynyInfo
- Publication number
- PL383819A1 PL383819A1 PL383819A PL38381907A PL383819A1 PL 383819 A1 PL383819 A1 PL 383819A1 PL 383819 A PL383819 A PL 383819A PL 38381907 A PL38381907 A PL 38381907A PL 383819 A1 PL383819 A1 PL 383819A1
- Authority
- PL
- Poland
- Prior art keywords
- enzyme
- levostatin
- biocatalythic
- esterase
- reactor
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
- C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
- C12N11/06—Enzymes or microbial cells immobilised on or in an organic carrier attached to the carrier via a bridging agent
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
- C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
- C12N11/10—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a carbohydrate
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
- C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
- C12N11/10—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a carbohydrate
- C12N11/12—Cellulose or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PL383819A PL211815B1 (pl) | 2007-11-19 | 2007-11-19 | Enzym esteraza lowastatyny osadzony na nośniku nierozpuszczalnym w wodzie, sposób osadzania enzymu, zastosowanie enzymu esterazy lowastatyny osadzonego na nosniku nierozpuszczalnym w wodzie, przepływowy reaktor biokatalityczny ze złożem oraz sposób wytwarzania i/lub oczyszczania symwastatyny |
PCT/PL2008/000086 WO2009067032A1 (en) | 2007-11-19 | 2008-11-18 | Lovastatin esterase enzyme immobilized on solid support, process for enzyme immobilization, use of immobilized enzyme, biocatalytic flow reactor and process for preparation and/or purification of simvastatin |
EP08851525.9A EP2240569B1 (en) | 2007-11-19 | 2008-11-18 | Lovastatin esterase enzyme immobilized on solid support, process for enzyme immobilization, biocatalytic flow reactor and process for preparation and/or purification of simvastatin |
RU2010122385/10A RU2475538C2 (ru) | 2007-11-19 | 2008-11-18 | Фермент ловастатин эстераза, иммобилизованный на твердом носителе, способ иммобилизации фермента, биокатализируемый проточный реактор и способ очистки симвастатина |
US12/743,040 US20100240116A1 (en) | 2007-11-19 | 2008-11-18 | Lovastatin esterase enzyme immobilized on solid support, process for enzyme immobilization, use of immobilized enzyme, biocatalytic flow reactor and process for preparation and/or purification of simvastatin |
CN200880114612A CN101848988A (zh) | 2007-11-19 | 2008-11-18 | 固定在固体载体上的洛伐他汀酯酶、酶固定化的方法、固定化酶的应用、生物催化流动反应器以及制备和/或纯化辛伐他汀的方法 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PL383819A PL211815B1 (pl) | 2007-11-19 | 2007-11-19 | Enzym esteraza lowastatyny osadzony na nośniku nierozpuszczalnym w wodzie, sposób osadzania enzymu, zastosowanie enzymu esterazy lowastatyny osadzonego na nosniku nierozpuszczalnym w wodzie, przepływowy reaktor biokatalityczny ze złożem oraz sposób wytwarzania i/lub oczyszczania symwastatyny |
Publications (2)
Publication Number | Publication Date |
---|---|
PL383819A1 true PL383819A1 (pl) | 2009-05-25 |
PL211815B1 PL211815B1 (pl) | 2012-06-29 |
Family
ID=40307641
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL383819A PL211815B1 (pl) | 2007-11-19 | 2007-11-19 | Enzym esteraza lowastatyny osadzony na nośniku nierozpuszczalnym w wodzie, sposób osadzania enzymu, zastosowanie enzymu esterazy lowastatyny osadzonego na nosniku nierozpuszczalnym w wodzie, przepływowy reaktor biokatalityczny ze złożem oraz sposób wytwarzania i/lub oczyszczania symwastatyny |
Country Status (6)
Country | Link |
---|---|
US (1) | US20100240116A1 (pl) |
EP (1) | EP2240569B1 (pl) |
CN (1) | CN101848988A (pl) |
PL (1) | PL211815B1 (pl) |
RU (1) | RU2475538C2 (pl) |
WO (1) | WO2009067032A1 (pl) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2490323C1 (ru) * | 2012-06-25 | 2013-08-20 | Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Санкт-Петербургский государственный технологический институт (технический университет)" | Микробиореактор и способ его эксплуатации |
IT201600095611A1 (it) * | 2016-09-23 | 2018-03-23 | Archimede R&D S R L | Materiale per la riduzione del contenuto di sostanze inquinanti e/o indesiderate, particolarmente in acqua e altri fluidi |
US11541105B2 (en) | 2018-06-01 | 2023-01-03 | The Research Foundation For The State University Of New York | Compositions and methods for disrupting biofilm formation and maintenance |
CN109402104B (zh) * | 2018-11-08 | 2020-07-17 | 山东鲁抗医药股份有限公司 | 一种头孢菌素酰化酶的固定化方法及固定化酶 |
CN115537410A (zh) * | 2022-09-27 | 2022-12-30 | 凯莱英医药化学(阜新)技术有限公司 | 酶固定化载体及其制备方法、固定化酶及其制备方法和应用 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3966897A (en) * | 1973-04-02 | 1976-06-29 | Marine Colloids, Inc. | Medium for use in bioassay and method of using same |
HU184468B (en) * | 1981-07-17 | 1984-08-28 | Reanal Finomvegyszergyar | Process for preparing immobilized cholinesterase enzyme preparation |
CA1188866A (en) * | 1983-03-11 | 1985-06-18 | Buckley Products Inc. | Roof ridge ventilator |
US4582915A (en) | 1983-10-11 | 1986-04-15 | Merck & Co., Inc. | Process for C-methylation of 2-methylbutyrates |
US5223415A (en) * | 1990-10-15 | 1993-06-29 | Merck & Co., Inc. | Biosynthetic production of 7-[1',2',6',7',8',8a'(R)-hexahydro-2'(S),6'(R)-dimethyl-8'(S)-hydroxy-1'(S)-naphthyl]-3(R),5(R)-dihydroxyheptanoic acid (triol acid) |
CA2053000C (en) * | 1990-10-15 | 1995-08-29 | Michael J. Conder | Biosynthetic production of 6(r)-[2-(8(s)-hydroxy-2(s), 6(r)-dimethyl-1,2,6,7,8,8a(r)-hexahydronaphthyl)-ethyl]-4 (r)-hydroxy-3,4,5,6-tetrahydro-2h-pyran-2-one triol acid by enzymatic hydrolysis of lovastatin acid using an enzyme derived from__lonostachys compactiuscula |
SI20070A (sl) * | 1998-09-18 | 2000-04-30 | LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. | Nove soli inhibitorjev HMG-CoA reduktaze |
JP4731489B2 (ja) * | 2003-10-21 | 2011-07-27 | ヴェレニウム コーポレイション | シンバスタチン及び中間体の製造方法 |
WO2007036235A1 (en) * | 2005-09-30 | 2007-04-05 | Novozymes A/S | Immobilization of enzymes |
-
2007
- 2007-11-19 PL PL383819A patent/PL211815B1/pl unknown
-
2008
- 2008-11-18 RU RU2010122385/10A patent/RU2475538C2/ru not_active IP Right Cessation
- 2008-11-18 EP EP08851525.9A patent/EP2240569B1/en not_active Not-in-force
- 2008-11-18 WO PCT/PL2008/000086 patent/WO2009067032A1/en active Application Filing
- 2008-11-18 CN CN200880114612A patent/CN101848988A/zh active Pending
- 2008-11-18 US US12/743,040 patent/US20100240116A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO2009067032A1 (en) | 2009-05-28 |
US20100240116A1 (en) | 2010-09-23 |
EP2240569A1 (en) | 2010-10-20 |
RU2010122385A (ru) | 2011-12-27 |
CN101848988A (zh) | 2010-09-29 |
RU2475538C2 (ru) | 2013-02-20 |
EP2240569B1 (en) | 2013-09-11 |
PL211815B1 (pl) | 2012-06-29 |
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