PL3638204T3 - Peptyd tpx-100 łagodzący ból stawu kolanowego - Google Patents

Peptyd tpx-100 łagodzący ból stawu kolanowego

Info

Publication number
PL3638204T3
PL3638204T3 PL18816758.9T PL18816758T PL3638204T3 PL 3638204 T3 PL3638204 T3 PL 3638204T3 PL 18816758 T PL18816758 T PL 18816758T PL 3638204 T3 PL3638204 T3 PL 3638204T3
Authority
PL
Poland
Prior art keywords
tpx
peptide
knee joint
joint pain
alleviating knee
Prior art date
Application number
PL18816758.9T
Other languages
English (en)
Inventor
Yoshinari Kumagai
Dawn Mcguire
Meghan MILLER
David Rosen
Original Assignee
Orthotrophix, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orthotrophix, Inc. filed Critical Orthotrophix, Inc.
Publication of PL3638204T3 publication Critical patent/PL3638204T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/45—For evaluating or diagnosing the musculoskeletal system or teeth
    • A61B5/4538—Evaluating a particular part of the muscoloskeletal system or a particular medical condition
    • A61B5/4585—Evaluating the knee
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728—Hyaluronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/473—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used alpha-Glycoproteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/48—Other medical applications
    • A61B5/4824—Touch or pain perception evaluation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Dermatology (AREA)
  • Biophysics (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Inorganic Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Surgery (AREA)
  • Dentistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PL18816758.9T 2017-06-14 2018-06-12 Peptyd tpx-100 łagodzący ból stawu kolanowego PL3638204T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762519538P 2017-06-14 2017-06-14
PCT/US2018/037058 WO2018231793A1 (en) 2017-06-14 2018-06-12 Method of alleviating joint pain

Publications (1)

Publication Number Publication Date
PL3638204T3 true PL3638204T3 (pl) 2024-07-29

Family

ID=64660479

Family Applications (1)

Application Number Title Priority Date Filing Date
PL18816758.9T PL3638204T3 (pl) 2017-06-14 2018-06-12 Peptyd tpx-100 łagodzący ból stawu kolanowego

Country Status (9)

Country Link
US (5) US10849958B2 (pl)
EP (2) EP4406598A3 (pl)
JP (2) JP7012383B2 (pl)
ES (1) ES2983699T3 (pl)
HR (1) HRP20240905T1 (pl)
HU (1) HUE067390T2 (pl)
PL (1) PL3638204T3 (pl)
RS (1) RS65680B1 (pl)
WO (1) WO2018231793A1 (pl)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11963996B2 (en) 2018-10-24 2024-04-23 Orthotrophix, Inc. Method of treating knee pain
WO2020117360A1 (en) * 2018-12-04 2020-06-11 Orthotrophix, Inc. Formulation for use in treating osteoarthritis
KR20210098998A (ko) 2018-12-04 2021-08-11 오르토트로픽스 인코포레이티드 골관절염 치료시 사용하기 위한 제형
US11793857B2 (en) * 2020-10-01 2023-10-24 Orthotrophix, Inc. Hard tissue therapeutics

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6911425B2 (en) 2000-08-16 2005-06-28 Acologix, Inc. Integrin binding motif containing peptides and methods of treating skeletal diseases
WO2007011610A2 (en) 2005-07-18 2007-01-25 Acologix, Inc. Protein formulation for promoting hard tissue formation
AU2008209473B2 (en) 2007-01-22 2012-10-25 Orthotrophix, Inc. A peptide composition and a method of promoting cartilage formation

Also Published As

Publication number Publication date
EP3638204A4 (en) 2021-04-14
JP2022058550A (ja) 2022-04-12
US11413327B2 (en) 2022-08-16
EP4406598A3 (en) 2024-10-30
ES2983699T3 (es) 2024-10-24
EP3638204A1 (en) 2020-04-22
EP4406598A2 (en) 2024-07-31
HUE067390T2 (hu) 2024-10-28
US20210236595A1 (en) 2021-08-05
US20190388503A1 (en) 2019-12-26
RS65680B1 (sr) 2024-07-31
EP3638204C0 (en) 2024-06-05
US11389505B2 (en) 2022-07-19
HRP20240905T1 (hr) 2024-10-25
JP7300768B2 (ja) 2023-06-30
JP7012383B2 (ja) 2022-02-14
US20210238237A1 (en) 2021-08-05
US20200002393A1 (en) 2020-01-02
US10849958B2 (en) 2020-12-01
US10849959B2 (en) 2020-12-01
US10849957B2 (en) 2020-12-01
WO2018231793A1 (en) 2018-12-20
US20200009220A1 (en) 2020-01-09
JP2020524671A (ja) 2020-08-20
EP3638204B1 (en) 2024-06-05

Similar Documents

Publication Publication Date Title
IL253712B (en) Mysterlein derivatives for coupling and healing
PL3592177T3 (pl) Urządzenia siłowników dla stawów ludzkich egzoszkieletów
PL3089711T3 (pl) Proteza stawu kolanowego
IL265463A (en) Therapeutic peptides related to mots-c
EP3649989A4 (en) ARTIFICIAL ARTICULATION OF THE KNEE OF THE HEMI-CONDYL TYPE
PL2954879T3 (pl) Bandaż do stawu kolanowego
SG11201607151RA (en) Ankle joint bandage
IL257574A (en) Prosthesis for replacing joint in a human hand or foot
EP3649988A4 (en) ARTIFICIAL KNEE JOINT
PL3638204T3 (pl) Peptyd tpx-100 łagodzący ból stawu kolanowego
ZA201803320B (en) Pharmaceutical compositions for treating pain
PL3415802T3 (pl) Dylatacja
SG11201912720XA (en) Joint system
SMT202400050T1 (it) Composti per migliorare il dolore
GB201706542D0 (en) Improvements in joint forming devices
PL3450901T3 (pl) Przegub o regulowanym położeniu kątowym
PL3058897T3 (pl) Endoproteza do artrodezy stawu kolanowego
GB201720115D0 (en) Mobility aid
GB201611034D0 (en) Anatomical joint
GB201503838D0 (en) Knee prosthesis
CA187336S (en) Knee warmer
IL268046B1 (en) Therapeutic peptides
EP3477016C0 (de) Variable fugenabdeckvorrichtung
GB2559213B (en) Prosthetic limb
PL3381423T3 (pl) Mankiet do leczenia ortotycznego