PL3606515T4 - Preparat inhibitora STAT3 - Google Patents

Preparat inhibitora STAT3

Info

Publication number
PL3606515T4
PL3606515T4 PL18720845T PL18720845T PL3606515T4 PL 3606515 T4 PL3606515 T4 PL 3606515T4 PL 18720845 T PL18720845 T PL 18720845T PL 18720845 T PL18720845 T PL 18720845T PL 3606515 T4 PL3606515 T4 PL 3606515T4
Authority
PL
Poland
Prior art keywords
inhibitor formulation
stat3 inhibitor
stat3
formulation
inhibitor
Prior art date
Application number
PL18720845T
Other languages
English (en)
Other versions
PL3606515T3 (pl
Inventor
Robert H. Shoemaker
Jonathan M. WHITE
Shanker Gupta
Original Assignee
The U.S.A. As Represented By The Secretary, Department Of Health And Human Services
Glg Pharma, Llc
Mri Global
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The U.S.A. As Represented By The Secretary, Department Of Health And Human Services, Glg Pharma, Llc, Mri Global filed Critical The U.S.A. As Represented By The Secretary, Department Of Health And Human Services
Publication of PL3606515T4 publication Critical patent/PL3606515T4/pl
Publication of PL3606515T3 publication Critical patent/PL3606515T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/63—Esters of sulfonic acids
    • C07C309/72—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C309/73—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton to carbon atoms of non-condensed six-membered aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C215/04—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated
    • C07C215/06—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic
    • C07C215/10—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic with one amino group and at least two hydroxy groups bound to the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
PL18720845T 2017-04-05 2018-04-05 Preparat inhibitora STAT3 PL3606515T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762481960P 2017-04-05 2017-04-05
EP18720845.9A EP3606515B1 (en) 2017-04-05 2018-04-05 Stat3 inhibitor formulation
PCT/US2018/026228 WO2018187551A1 (en) 2017-04-05 2018-04-05 Stat3 inhibitor formulation

Publications (2)

Publication Number Publication Date
PL3606515T4 true PL3606515T4 (pl) 2022-02-14
PL3606515T3 PL3606515T3 (pl) 2022-02-14

Family

ID=62067809

Family Applications (1)

Application Number Title Priority Date Filing Date
PL18720845T PL3606515T3 (pl) 2017-04-05 2018-04-05 Preparat inhibitora STAT3

Country Status (15)

Country Link
US (1) US10913709B2 (pl)
EP (1) EP3606515B1 (pl)
JP (1) JP2020513022A (pl)
KR (1) KR20200043930A (pl)
CN (1) CN110944631A (pl)
AU (1) AU2018248303A1 (pl)
BR (1) BR112019020985A2 (pl)
CA (1) CA3058973A1 (pl)
CL (1) CL2019002843A1 (pl)
CO (1) CO2019012386A2 (pl)
ES (1) ES2888235T3 (pl)
MX (1) MX386463B (pl)
PE (1) PE20200611A1 (pl)
PL (1) PL3606515T3 (pl)
WO (1) WO2018187551A1 (pl)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6191285B1 (en) 1997-07-03 2001-02-20 Abbott Laboratories Process for the preparation of ketorolac tromethamine
US7960434B2 (en) 2006-05-19 2011-06-14 University Of South Florida Small molecule inhibitors of STAT3 with anti-tumor activity
WO2010062681A2 (en) 2008-10-30 2010-06-03 University Of South Florida Luteolin and diosmin/diosmetin as novel stat3 inhibitors for treating autism
WO2010065444A1 (en) * 2008-12-01 2010-06-10 University Of Central Florida Research Foundation, Inc. Drug composition cytotoxic for pancreatic cancer cells
US9572787B2 (en) 2011-05-19 2017-02-21 Rhode Island Hospital Inhibition of renal fibrosis
US20170304386A1 (en) * 2014-10-08 2017-10-26 Shih-Chieh Hung Method for inhibiting survival, tumorigenesis and metastasis of cancer cells and/or cancer stem cells

Also Published As

Publication number Publication date
JP2020513022A (ja) 2020-04-30
EP3606515B1 (en) 2021-06-02
PE20200611A1 (es) 2020-03-10
CL2019002843A1 (es) 2020-06-12
CN110944631A (zh) 2020-03-31
US10913709B2 (en) 2021-02-09
MX2019011913A (es) 2021-09-24
WO2018187551A1 (en) 2018-10-11
KR20200043930A (ko) 2020-04-28
CO2019012386A2 (es) 2020-01-31
PL3606515T3 (pl) 2022-02-14
US20200109109A1 (en) 2020-04-09
ES2888235T3 (es) 2022-01-03
BR112019020985A2 (pt) 2020-05-05
AU2018248303A1 (en) 2019-11-07
CA3058973A1 (en) 2018-10-11
EP3606515A1 (en) 2020-02-12
MX386463B (es) 2025-03-18

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