PL3548633T3 - Zastosowanie epigenetycznych interakcji chromosomów w diagnostyce nowotworów - Google Patents

Zastosowanie epigenetycznych interakcji chromosomów w diagnostyce nowotworów

Info

Publication number
PL3548633T3
PL3548633T3 PL17817030.4T PL17817030T PL3548633T3 PL 3548633 T3 PL3548633 T3 PL 3548633T3 PL 17817030 T PL17817030 T PL 17817030T PL 3548633 T3 PL3548633 T3 PL 3548633T3
Authority
PL
Poland
Prior art keywords
chromsomal
epigenetic
interactions
application
cancer diagnostics
Prior art date
Application number
PL17817030.4T
Other languages
English (en)
Polish (pl)
Inventor
Francis Hector GRAND
Aroul Selvam Ramadass
Alexandre Akoulitchev
Ewan HUNTER
Original Assignee
Oxford BioDynamics PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oxford BioDynamics PLC filed Critical Oxford BioDynamics PLC
Publication of PL3548633T3 publication Critical patent/PL3548633T3/pl

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6827Hybridisation assays for detection of mutation or polymorphism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2521/00Reaction characterised by the enzymatic activity
    • C12Q2521/30Phosphoric diester hydrolysing, i.e. nuclease
    • C12Q2521/301Endonuclease
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2521/00Reaction characterised by the enzymatic activity
    • C12Q2521/50Other enzymatic activities
    • C12Q2521/501Ligase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2523/00Reactions characterised by treatment of reaction samples
    • C12Q2523/10Characterised by chemical treatment
    • C12Q2523/101Crosslinking agents, e.g. psoralen
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2565/00Nucleic acid analysis characterised by mode or means of detection
    • C12Q2565/50Detection characterised by immobilisation to a surface
    • C12Q2565/501Detection characterised by immobilisation to a surface being an array of oligonucleotides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PL17817030.4T 2016-12-01 2017-11-30 Zastosowanie epigenetycznych interakcji chromosomów w diagnostyce nowotworów PL3548633T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662428893P 2016-12-01 2016-12-01
PCT/GB2017/053615 WO2018100381A1 (en) 2016-12-01 2017-11-30 Application of epigenetic chromsomal interactions in cancer diagnostics

Publications (1)

Publication Number Publication Date
PL3548633T3 true PL3548633T3 (pl) 2024-04-02

Family

ID=60702831

Family Applications (1)

Application Number Title Priority Date Filing Date
PL17817030.4T PL3548633T3 (pl) 2016-12-01 2017-11-30 Zastosowanie epigenetycznych interakcji chromosomów w diagnostyce nowotworów

Country Status (12)

Country Link
US (2) US11560597B2 (enExample)
EP (2) EP4357463A3 (enExample)
JP (2) JP2019535295A (enExample)
KR (1) KR102481242B1 (enExample)
CN (1) CN110234769B (enExample)
AU (1) AU2017367245B2 (enExample)
CA (1) CA3045070A1 (enExample)
ES (1) ES2971286T3 (enExample)
MY (1) MY190153A (enExample)
PL (1) PL3548633T3 (enExample)
TW (1) TWI865427B (enExample)
WO (1) WO2018100381A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020225551A1 (en) * 2019-05-08 2020-11-12 Oxford BioDynamics PLC Chromosome conformation markers of prostate cancer and lymphoma
CN118506860B (zh) * 2024-07-18 2024-10-08 广州女娲生命科技有限公司 药物表观遗传安全性评价的检测分析方法及系统

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ564262A (en) * 2005-07-04 2010-02-26 Univ Erasmus Medical Ct Chromosome conformation capture-on-chip (4C) assay
GB0603251D0 (en) * 2006-02-17 2006-03-29 Isis Innovation DNA conformation
AU2008204338B2 (en) * 2007-01-11 2014-03-06 Erasmus University Medical Center Circular chromosome conformation capture (4C)
CA2609172A1 (en) * 2007-10-31 2009-04-30 University Of Utah Research Foundation Immunotherapy compositions for use with targeted therapy in the treatment of cancer
GB0810051D0 (en) * 2008-06-02 2008-07-09 Oxford Biodynamics Ltd Method of diagnosis
WO2010036323A1 (en) 2008-09-25 2010-04-01 University Of Massachusetts Medical School Method of identifing interactions between genomic loci
EP2366162A1 (en) * 2008-11-18 2011-09-21 Collabrx, Inc. Individualized cancer treatment
CA2804450C (en) * 2010-07-09 2022-10-11 Max Jan van Min 3-d genomic region of interest sequencing strategies
US20140056898A1 (en) * 2011-02-24 2014-02-27 Bo Zhang Combination therapies comprising anti-erbb3 agents
EP2710146A2 (en) * 2011-05-18 2014-03-26 Life Technologies Corporation Chromosome conformation analysis
AU2013280644B2 (en) * 2012-06-26 2018-08-02 Jeffrey A. BACHA Methods for treating tyrosine-kinase-inhibitor-resistant malignancies in patients with genetic polymorphisms or AHI1 dysregulations or mutations employing dianhydrogalactitol, diacetyldianhydrogalactitol, dibromodulcitol, or analogs or derivatives thereof
CN102827935B (zh) * 2012-08-29 2013-12-18 北京大学人民医院 定量检测FIP1L1-PDGFRA融合基因mRNA水平的试剂盒
GB201320351D0 (en) * 2013-11-18 2014-01-01 Erasmus Universiteit Medisch Ct Method
JP2018518203A (ja) 2015-06-24 2018-07-12 オックスフォード バイオダイナミックス リミテッド エピジェネティックな染色体相互作用
EP3390656B1 (en) * 2015-12-14 2020-04-08 The General Hospital Corporation Methods of detecting insulator dysfunction and oncogene activation for screening, diagnosis and treatment of patients in need thereof
GB201608000D0 (en) 2016-05-06 2016-06-22 Oxford Biodynamics Ltd Chromosome detection

Also Published As

Publication number Publication date
WO2018100381A1 (en) 2018-06-07
CA3045070A1 (en) 2018-06-07
TW201842190A (zh) 2018-12-01
ES2971286T3 (es) 2024-06-04
TWI865427B (zh) 2024-12-11
NZ753716A (en) 2024-05-31
MY190153A (en) 2022-03-31
KR20190086569A (ko) 2019-07-22
CN110234769B (zh) 2024-06-07
US11560597B2 (en) 2023-01-24
KR102481242B1 (ko) 2022-12-23
AU2017367245B2 (en) 2020-09-24
EP3548633B1 (en) 2024-01-24
JP2023027076A (ja) 2023-03-01
US20230082230A1 (en) 2023-03-16
EP4357463A3 (en) 2024-07-17
EP3548633A1 (en) 2019-10-09
EP3548633C0 (en) 2024-01-24
JP7579003B2 (ja) 2024-11-07
AU2017367245A1 (en) 2019-06-06
CN110234769A (zh) 2019-09-13
EP4357463A2 (en) 2024-04-24
US20190338367A1 (en) 2019-11-07
JP2019535295A (ja) 2019-12-12

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