PL346955A1 - Novel derivatives of genistein and pharmacological agents containing such derivatives - Google Patents

Novel derivatives of genistein and pharmacological agents containing such derivatives

Info

Publication number
PL346955A1
PL346955A1 PL01346955A PL34695501A PL346955A1 PL 346955 A1 PL346955 A1 PL 346955A1 PL 01346955 A PL01346955 A PL 01346955A PL 34695501 A PL34695501 A PL 34695501A PL 346955 A1 PL346955 A1 PL 346955A1
Authority
PL
Poland
Prior art keywords
derivatives
genistein
pharmacological agents
agents containing
novel
Prior art date
Application number
PL01346955A
Other versions
PL205635B1 (en
Inventor
Osman Achmatowicz
Grzegorz Grynkiewicz
Wieslaw Pucko
Aleksander P Mazurek
Krzysztof Polkowski
Jerzy Boryski
Wieslaw Szeja
Wieslaw Szelejewski
Adam Opolski
Gabriela Pastuch-Gawolek
Czeslaw Radzikowski
Barbara Szechner
Joanna Wietrzyk
Janusz Skierski
Ilona Wandzik
Piotr Krzeczynski
Original Assignee
Inst Farmaceutyczny
Inst Lekow
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inst Farmaceutyczny, Inst Lekow filed Critical Inst Farmaceutyczny
Priority to PL346955A priority Critical patent/PL205635B1/en
Priority to PCT/PL2002/000029 priority patent/WO2002081491A2/en
Publication of PL346955A1 publication Critical patent/PL346955A1/en
Publication of PL205635B1 publication Critical patent/PL205635B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
    • C07D311/34—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 3 only
    • C07D311/36—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 3 only not hydrogenated in the hetero ring, e.g. isoflavones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
PL346955A 2001-04-09 2001-04-09 Novel derivatives of genistein and pharmacological agents containing such derivatives PL205635B1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
PL346955A PL205635B1 (en) 2001-04-09 2001-04-09 Novel derivatives of genistein and pharmacological agents containing such derivatives
PCT/PL2002/000029 WO2002081491A2 (en) 2001-04-09 2002-04-08 New genistein derivatives and pharmaceutical preparations containing them

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL346955A PL205635B1 (en) 2001-04-09 2001-04-09 Novel derivatives of genistein and pharmacological agents containing such derivatives

Publications (2)

Publication Number Publication Date
PL346955A1 true PL346955A1 (en) 2002-10-21
PL205635B1 PL205635B1 (en) 2010-05-31

Family

ID=20078583

Family Applications (1)

Application Number Title Priority Date Filing Date
PL346955A PL205635B1 (en) 2001-04-09 2001-04-09 Novel derivatives of genistein and pharmacological agents containing such derivatives

Country Status (2)

Country Link
PL (1) PL205635B1 (en)
WO (1) WO2002081491A2 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4654187B2 (en) * 2003-05-15 2011-03-16 成都迪康▲ヤオ▼物研究所 Isoflavone derivatives of tectorigenin, their preparation, and antiviral agents containing them as active ingredients
WO2007001348A2 (en) * 2004-08-26 2007-01-04 The Ohio State University Research Foundation Heteroaryl-containing isoflavones as aromatase inhibitors
KR101849059B1 (en) * 2008-12-11 2018-04-13 악센투아 파마슈투칼스 아베 Crystalline forms of genistein
PL399467A1 (en) 2012-06-08 2013-12-09 3G Therapeutics Inc. The use of genistein for lowering the storage organic compounds in cells in the treatment and/or prevention of lysosomal storage diseases
CN104974204B (en) * 2015-06-19 2017-12-19 武汉光谷人福生物医药有限公司 The method and system of separating flavone oxygen glycosides compound monomer is extracted from Desmodium styracifolium
CN107652261B (en) * 2017-09-30 2020-08-07 桂林医学院 Calycosin derivative and synthetic method thereof
WO2023212130A1 (en) * 2022-04-28 2023-11-02 GreenStone Biosciences, Inc. Treatment of the adverse cardiovascular effects of cannabinoids

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5911995A (en) * 1994-08-19 1999-06-15 Regents Of The University Of Minnesota EGF-genistein conjugates for the treatment of cancer
ATE286038T1 (en) * 1996-03-05 2005-01-15 Sterix Ltd COMPOUNDS WITH SULFONIC ACID AMIDE GROUP
WO1998011876A1 (en) * 1996-09-18 1998-03-26 Marigen S.A. Bioflavonol glycoside peroxy esters and their preparation for pharmacologically effective concentrations and ultramicroemulsions
WO1998048790A1 (en) * 1997-04-28 1998-11-05 Anticancer, Inc. Use of genistein and related compounds to treat certain sex hormone related conditions
AU1289899A (en) * 1997-10-31 1999-05-24 Arch Development Corporation Methods and compositions for regulation of 5-alpha reductase activity
FR2781154B1 (en) * 1998-07-15 2001-09-07 Lafon Labor THERAPEUTIC COMPOSITION BASED ON ISOFLAVONOIDS FOR USE IN THE TREATMENT OF TUMORS WITH CYTOTOXIC AGENTS
AUPQ008299A0 (en) * 1999-04-30 1999-05-27 G.J. Consultants Pty Ltd Isoflavone metabolites
GB9920912D0 (en) * 1999-09-03 1999-11-10 Indena Spa Novel derivatives of flavones,xanthones and coumarins
US20010047032A1 (en) * 1999-12-30 2001-11-29 Castillo Gerardo M. Polyhydroxylated aromatic compounds for the treatment of amyloidosis and alpha-synuclein fibril diseases

Also Published As

Publication number Publication date
PL205635B1 (en) 2010-05-31
WO2002081491A3 (en) 2004-02-26
WO2002081491A2 (en) 2002-10-17

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