PL342852A1 - Tumor-associated antigen derivatives from the mage family, and nucleic acid sequences encoding them, used for the preparation of fusion proteins and of compositions for vaccination - Google Patents

Tumor-associated antigen derivatives from the mage family, and nucleic acid sequences encoding them, used for the preparation of fusion proteins and of compositions for vaccination

Info

Publication number
PL342852A1
PL342852A1 PL99342852A PL34285299A PL342852A1 PL 342852 A1 PL342852 A1 PL 342852A1 PL 99342852 A PL99342852 A PL 99342852A PL 34285299 A PL34285299 A PL 34285299A PL 342852 A1 PL342852 A1 PL 342852A1
Authority
PL
Poland
Prior art keywords
vaccination
tumor
compositions
preparation
nucleic acid
Prior art date
Application number
PL99342852A
Other versions
PL203645B1 (en
Inventor
Silva Teresa Cabezon
Joseph Cohen
Moncef Mohamed Slaoui
Bassols Carlota Vinals
Original Assignee
Smithkline Beecham Biolog
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9802543.0A external-priority patent/GB9802543D0/en
Priority claimed from GBGB9802650.3A external-priority patent/GB9802650D0/en
Application filed by Smithkline Beecham Biolog filed Critical Smithkline Beecham Biolog
Publication of PL342852A1 publication Critical patent/PL342852A1/en
Publication of PL203645B1 publication Critical patent/PL203645B1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A61K39/001184—Cancer testis antigens, e.g. SSX, BAGE, GAGE or SAGE
    • A61K39/001186—MAGE
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/245—Escherichia (G)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/285—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pasteurellaceae (F), e.g. Haemophilus influenza
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • C07K14/3156—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci from Streptococcus pneumoniae (Pneumococcus)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55577—Saponins; Quil A; QS21; ISCOMS
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6068—Other bacterial proteins, e.g. OMP
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Oncology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
PL342852A 1998-02-05 1999-02-02 MAGE family tumor-associated antigen derivative and use, nucleic acid sequence and use thereof, vector, host cell, vaccine, method of purifying MAGE protein or a derivative thereof, and method of making a vaccine PL203645B1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GBGB9802543.0A GB9802543D0 (en) 1998-02-05 1998-02-05 Vaccine
GB9802543.0 1998-02-05
GBGB9802650.3A GB9802650D0 (en) 1998-02-06 1998-02-06 Vaccine
GB9802650.3 1998-02-06
PCT/EP1999/000660 WO1999040188A2 (en) 1998-02-05 1999-02-02 Tumor-associated antigen derivatives from the mage family, and nucleic acid sequences encoding them, used for the preparation of fusion proteins and of compositions for vaccinations

Publications (2)

Publication Number Publication Date
PL342852A1 true PL342852A1 (en) 2001-07-16
PL203645B1 PL203645B1 (en) 2009-10-30

Family

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Also Published As

Publication number Publication date
ATE462788T1 (en) 2010-04-15
IL179010A0 (en) 2007-03-08
DK1659179T3 (en) 2011-10-10
KR100824105B1 (en) 2008-04-21
CN1295616A (en) 2001-05-16
TR200002284T2 (en) 2000-11-21
CZ298347B6 (en) 2007-09-05
CA2584482C (en) 2012-03-27
CN1227360C (en) 2005-11-16
DE69929310D1 (en) 2006-03-30
AR018064A1 (en) 2001-10-31
KR100633212B1 (en) 2006-10-11
PT1659178E (en) 2010-06-28
NZ506086A (en) 2003-01-31
BR9907691A (en) 2000-11-14
HU228467B1 (en) 2013-03-28
ATE315088T1 (en) 2006-02-15
DK1053325T3 (en) 2006-05-22
US8097257B2 (en) 2012-01-17
IL137442A (en) 2008-04-13
EP1584685A3 (en) 2005-12-07
CY1111672T1 (en) 2015-10-07
NO20003958D0 (en) 2000-08-04
US20100209444A1 (en) 2010-08-19
AU737337B2 (en) 2001-08-16
EP1659179B1 (en) 2011-06-15
CA2584482A1 (en) 1999-08-12
ES2342416T3 (en) 2010-07-06
PT1053325E (en) 2006-05-31
IL188875A0 (en) 2009-02-11
WO1999040188A3 (en) 1999-10-14
SI1659178T1 (en) 2010-07-30
HK1093521A1 (en) 2007-03-02
CY1111831T1 (en) 2015-10-07
EP1659179A3 (en) 2007-01-17
KR20010040675A (en) 2001-05-15
EP1584685A2 (en) 2005-10-12
KR20060067977A (en) 2006-06-20
NO20003958L (en) 2000-10-04
DE69942214D1 (en) 2010-05-12
DE69929310T2 (en) 2006-08-03
ATE505542T1 (en) 2011-04-15
CY1105685T1 (en) 2010-12-22
NO331719B1 (en) 2012-03-05
JP2009201510A (en) 2009-09-10
PT1659179E (en) 2011-09-16
HK1093522A1 (en) 2007-03-02
US8044183B2 (en) 2011-10-25
CZ20002869A3 (en) 2001-01-17
DE69943359D1 (en) 2011-05-26
SI1584685T1 (en) 2011-07-29
WO1999040188A2 (en) 1999-08-12
EP1659179A2 (en) 2006-05-24
US20100204458A1 (en) 2010-08-12
CZ298364B6 (en) 2007-09-05
SA99200126B1 (en) 2006-08-20
CA2319309C (en) 2010-08-10
US8597656B2 (en) 2013-12-03
EP1053325B1 (en) 2006-01-04
HUP0102639A1 (en) 2001-11-28
AU2722099A (en) 1999-08-23
SI1053325T1 (en) 2006-06-30
CA2319309A1 (en) 1999-08-12
BR9907691B1 (en) 2011-05-31
EP1659178A2 (en) 2006-05-24
EP1053325A2 (en) 2000-11-22
ATE513042T1 (en) 2011-07-15
HK1033838A1 (en) 2001-09-28
IL137442A0 (en) 2001-07-24
HK1083026A1 (en) 2006-06-23
IL188875A (en) 2011-08-31
CY1110180T1 (en) 2015-01-14
JP4768121B2 (en) 2011-09-07
JP2002502604A (en) 2002-01-29
SI1659179T1 (en) 2011-10-28
EP1659178B1 (en) 2010-03-31
ES2255248T3 (en) 2006-06-16
TWI238853B (en) 2005-09-01
PT1584685E (en) 2011-06-17
NO328507B1 (en) 2010-03-08
DK1584685T3 (en) 2011-07-11
EP1659178A3 (en) 2007-01-17
EP1584685B1 (en) 2011-04-13
DK1659178T3 (en) 2010-07-12
US20120269835A1 (en) 2012-10-25
NO20091665L (en) 2000-10-04
HUP0102639A3 (en) 2004-04-28

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