PL3374358T3 - Pochodne azetydyny do obrazowania białka tau - Google Patents
Pochodne azetydyny do obrazowania białka tauInfo
- Publication number
- PL3374358T3 PL3374358T3 PL16798874T PL16798874T PL3374358T3 PL 3374358 T3 PL3374358 T3 PL 3374358T3 PL 16798874 T PL16798874 T PL 16798874T PL 16798874 T PL16798874 T PL 16798874T PL 3374358 T3 PL3374358 T3 PL 3374358T3
- Authority
- PL
- Poland
- Prior art keywords
- azetidine derivatives
- tau imaging
- tau
- imaging
- azetidine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/041—Heterocyclic compounds
- A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
- A61K51/0444—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having four-membered rings, e.g. azetidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/041—Heterocyclic compounds
- A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
- A61K51/0453—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/041—Heterocyclic compounds
- A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
- A61K51/0455—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
- C07B59/002—Heterocyclic compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/05—Isotopically modified compounds, e.g. labelled
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Physics & Mathematics (AREA)
- Epidemiology (AREA)
- Optics & Photonics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Plural Heterocyclic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562254906P | 2015-11-13 | 2015-11-13 | |
PCT/US2016/060621 WO2017083198A1 (en) | 2015-11-13 | 2016-11-04 | Azetidine derivatives for tau imaging |
EP16798874.0A EP3374358B1 (en) | 2015-11-13 | 2016-11-04 | Azetidine derivatives for tau imaging |
Publications (1)
Publication Number | Publication Date |
---|---|
PL3374358T3 true PL3374358T3 (pl) | 2021-07-12 |
Family
ID=57389526
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL16798874T PL3374358T3 (pl) | 2015-11-13 | 2016-11-04 | Pochodne azetydyny do obrazowania białka tau |
Country Status (19)
Country | Link |
---|---|
US (1) | US10301308B2 (pl) |
EP (1) | EP3374358B1 (pl) |
JP (1) | JP2018531978A (pl) |
KR (1) | KR20180061364A (pl) |
CN (1) | CN108290883B (pl) |
AU (1) | AU2016351609B2 (pl) |
BR (1) | BR112018006969B1 (pl) |
CA (1) | CA3003884C (pl) |
DK (1) | DK3374358T3 (pl) |
EA (1) | EA034018B1 (pl) |
ES (1) | ES2864825T3 (pl) |
HK (1) | HK1257042A1 (pl) |
IL (1) | IL258313B (pl) |
MX (1) | MX2018005376A (pl) |
PL (1) | PL3374358T3 (pl) |
PT (1) | PT3374358T (pl) |
SA (1) | SA518391527B1 (pl) |
WO (1) | WO2017083198A1 (pl) |
ZA (1) | ZA201802526B (pl) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2023150483A1 (en) * | 2022-02-03 | 2023-08-10 | Eli Lilly And Company | Regional tau imaging for diagnosing and treating alzheimer's disease |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPWO2004054978A1 (ja) * | 2002-12-16 | 2006-04-20 | 株式会社 ビーエフ研究所 | タウ蛋白蓄積性疾患の診断プローブとしてのキノリン誘導体 |
US20110046378A1 (en) | 2008-02-14 | 2011-02-24 | Siemens Medical Solutions Usa, Inc. | Novel Imaging Agents for Detecting Neurological Dysfunction |
PT2381967T (pt) * | 2008-12-31 | 2017-02-24 | Avid Radiopharmaceuticals Inc | Síntese de estirilpiridinas radiomarcadas com 18f a partir de precursores tosilato e as suas composições farmacêuticas estáveis |
US8691187B2 (en) | 2009-03-23 | 2014-04-08 | Eli Lilly And Company | Imaging agents for detecting neurological disorders |
WO2013176698A1 (en) | 2012-05-22 | 2013-11-28 | Eli Lilly And Company | Carboline and carbazole based imaging agents for detecting neurological dysfunction |
-
2016
- 2016-11-04 WO PCT/US2016/060621 patent/WO2017083198A1/en active Application Filing
- 2016-11-04 JP JP2018522120A patent/JP2018531978A/ja not_active Withdrawn
- 2016-11-04 BR BR112018006969-8A patent/BR112018006969B1/pt active IP Right Grant
- 2016-11-04 DK DK16798874.0T patent/DK3374358T3/da active
- 2016-11-04 US US15/763,608 patent/US10301308B2/en active Active
- 2016-11-04 PT PT167988740T patent/PT3374358T/pt unknown
- 2016-11-04 EA EA201890799A patent/EA034018B1/ru not_active IP Right Cessation
- 2016-11-04 CN CN201680066210.8A patent/CN108290883B/zh active Active
- 2016-11-04 CA CA3003884A patent/CA3003884C/en active Active
- 2016-11-04 EP EP16798874.0A patent/EP3374358B1/en active Active
- 2016-11-04 ES ES16798874T patent/ES2864825T3/es active Active
- 2016-11-04 KR KR1020187013117A patent/KR20180061364A/ko not_active Application Discontinuation
- 2016-11-04 AU AU2016351609A patent/AU2016351609B2/en active Active
- 2016-11-04 PL PL16798874T patent/PL3374358T3/pl unknown
- 2016-11-04 MX MX2018005376A patent/MX2018005376A/es unknown
-
2018
- 2018-03-22 IL IL258313A patent/IL258313B/en active IP Right Grant
- 2018-04-17 ZA ZA201802526A patent/ZA201802526B/en unknown
- 2018-05-07 SA SA518391527A patent/SA518391527B1/ar unknown
- 2018-12-18 HK HK18116177.1A patent/HK1257042A1/zh unknown
Also Published As
Publication number | Publication date |
---|---|
BR112018006969B1 (pt) | 2022-04-26 |
EP3374358B1 (en) | 2021-02-17 |
EA201890799A1 (ru) | 2018-10-31 |
WO2017083198A1 (en) | 2017-05-18 |
PT3374358T (pt) | 2021-03-31 |
AU2016351609A1 (en) | 2018-04-19 |
JP2018531978A (ja) | 2018-11-01 |
SA518391527B1 (ar) | 2021-02-07 |
IL258313A (en) | 2018-05-31 |
EA034018B1 (ru) | 2019-12-19 |
CA3003884C (en) | 2020-04-21 |
KR20180061364A (ko) | 2018-06-07 |
CN108290883A (zh) | 2018-07-17 |
IL258313B (en) | 2021-04-29 |
CA3003884A1 (en) | 2017-05-18 |
BR112018006969A2 (pt) | 2018-10-16 |
HK1257042A1 (zh) | 2019-10-11 |
AU2016351609B2 (en) | 2019-08-08 |
US10301308B2 (en) | 2019-05-28 |
US20180282322A1 (en) | 2018-10-04 |
ES2864825T3 (es) | 2021-10-14 |
MX2018005376A (es) | 2018-08-01 |
CN108290883B (zh) | 2021-02-09 |
ZA201802526B (en) | 2019-10-30 |
EP3374358A1 (en) | 2018-09-19 |
DK3374358T3 (da) | 2021-03-08 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK3478217T3 (en) | Historisk scanningsreference for intraorale scanninger | |
IL258213B (en) | Pharmaceutical compounds | |
GB201506658D0 (en) | Pharmaceutical compounds | |
IL258246A (en) | Pharmaceutical compounds | |
GB201504675D0 (en) | Pharmaceutical compounds | |
EP3322178A4 (en) | Imaging device | |
GB201506660D0 (en) | Pharmaceutical compounds | |
EP3321964A4 (en) | Imaging device | |
PL3226529T3 (pl) | Zapasy materiału do tworzenia obrazów | |
GB201519352D0 (en) | Pharmaceutical compounds | |
EP3250716A4 (en) | Microscope-free imaging | |
EP3280133A4 (en) | Imaging device | |
EP3396937A4 (en) | IMAGING DEVICE | |
EP3343912A4 (en) | IMAGING DEVICE | |
GB201506933D0 (en) | Pharmaceutical compounds | |
EP3392707A4 (en) | IMAGE FORMING DEVICE | |
GB201502567D0 (en) | Pharmaceutical compounds | |
EP3258312A4 (en) | Imaging device | |
EP3333627A4 (en) | IMAGING DEVICE | |
HK1220537A1 (zh) | 種單分子圖像糾偏裝置 | |
EP3288250A4 (en) | Imaging device | |
EP3352445A4 (en) | Imaging device | |
EP3285480A4 (en) | Imaging device | |
HK1257042A1 (zh) | 用於tau成像的氮雜環丁烷衍生物 | |
EP3188470A4 (en) | Imaging apparatus |