PL3237378T3 - Sposób wytwarzania bromku (3RS)-3-[(2SR)-(2-cyklopentylo-2-hydroksy-2-fenyloacetylo)oksy]-1,1-dimetylopirolidynium - Google Patents
Sposób wytwarzania bromku (3RS)-3-[(2SR)-(2-cyklopentylo-2-hydroksy-2-fenyloacetylo)oksy]-1,1-dimetylopirolidyniumInfo
- Publication number
- PL3237378T3 PL3237378T3 PL15808368T PL15808368T PL3237378T3 PL 3237378 T3 PL3237378 T3 PL 3237378T3 PL 15808368 T PL15808368 T PL 15808368T PL 15808368 T PL15808368 T PL 15808368T PL 3237378 T3 PL3237378 T3 PL 3237378T3
- Authority
- PL
- Poland
- Prior art keywords
- phenylacetyl
- cyclopentyl
- oxy
- hydroxy
- preparing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/12—Oxygen or sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP14382569 | 2014-12-24 | ||
PCT/EP2015/078668 WO2016102174A1 (en) | 2014-12-24 | 2015-12-04 | Process for preparing (3rs)-3-[(2sr)-(2-cyclopentyl-2-hydroxy-2-phenylacetyl)oxy]-1,1-dimethylpyrrolidinium bromide |
EP15808368.3A EP3237378B1 (en) | 2014-12-24 | 2015-12-04 | Process for preparing (3rs)-3-[(2sr)-(2-cyclopentyl-2-hydroxy-2-phenylacetyl)oxy]-1,1-dimethylpyrrolidinium bromide |
Publications (1)
Publication Number | Publication Date |
---|---|
PL3237378T3 true PL3237378T3 (pl) | 2019-06-28 |
Family
ID=52302106
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL15808368T PL3237378T3 (pl) | 2014-12-24 | 2015-12-04 | Sposób wytwarzania bromku (3RS)-3-[(2SR)-(2-cyklopentylo-2-hydroksy-2-fenyloacetylo)oksy]-1,1-dimetylopirolidynium |
Country Status (6)
Country | Link |
---|---|
US (1) | US10131630B2 (pl) |
EP (1) | EP3237378B1 (pl) |
JP (1) | JP2018501270A (pl) |
ES (1) | ES2700597T3 (pl) |
PL (1) | PL3237378T3 (pl) |
WO (1) | WO2016102174A1 (pl) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2805434T3 (es) | 2016-07-29 | 2021-02-12 | Inke Sa | Procedimiento de estabilización de tamaño de partícula |
CN113234003B (zh) * | 2021-04-23 | 2024-02-02 | 广东嘉博制药有限公司 | 一种格隆溴铵及其制备方法 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2956062A (en) * | 1959-02-26 | 1960-10-11 | Robins Co Inc A H | Esters of amino alcohols |
FI49713C (fi) * | 1974-05-15 | 1975-09-10 | Medica Pharma Co Ltd | Terapeuttisesti tehokkaan erytro-1-metyyli-3-pyrrolidinyyli-alfa-syklo -pentyylimandelaattimetobromidin valmistusmenetelmä. |
DK1371645T3 (da) * | 1996-11-11 | 2013-06-03 | Meda Pharma Gmbh & Co Kg | Anvendelse af (3S,2'R)-glycopyrronium som lægemiddel |
US9926270B2 (en) * | 2014-08-20 | 2018-03-27 | Dermira, Inc. | Process for production of glycopyrronium tosylate |
-
2015
- 2015-12-04 EP EP15808368.3A patent/EP3237378B1/en active Active
- 2015-12-04 JP JP2017534298A patent/JP2018501270A/ja active Pending
- 2015-12-04 PL PL15808368T patent/PL3237378T3/pl unknown
- 2015-12-04 ES ES15808368T patent/ES2700597T3/es active Active
- 2015-12-04 US US15/538,218 patent/US10131630B2/en active Active
- 2015-12-04 WO PCT/EP2015/078668 patent/WO2016102174A1/en active Application Filing
Also Published As
Publication number | Publication date |
---|---|
EP3237378B1 (en) | 2018-09-26 |
WO2016102174A1 (en) | 2016-06-30 |
ES2700597T3 (es) | 2019-02-18 |
EP3237378A1 (en) | 2017-11-01 |
US10131630B2 (en) | 2018-11-20 |
US20170334848A1 (en) | 2017-11-23 |
JP2018501270A (ja) | 2018-01-18 |
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