PL3206666T3 - Ciekła kompozycja farmaceutyczna zawierająca pemetreksed - Google Patents

Ciekła kompozycja farmaceutyczna zawierająca pemetreksed

Info

Publication number
PL3206666T3
PL3206666T3 PL15778927T PL15778927T PL3206666T3 PL 3206666 T3 PL3206666 T3 PL 3206666T3 PL 15778927 T PL15778927 T PL 15778927T PL 15778927 T PL15778927 T PL 15778927T PL 3206666 T3 PL3206666 T3 PL 3206666T3
Authority
PL
Poland
Prior art keywords
pemetrexed
pharmaceutical composition
liquid pharmaceutical
liquid
composition
Prior art date
Application number
PL15778927T
Other languages
English (en)
Inventor
Borek Zaludek
Original Assignee
Synthon B.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=51844505&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL3206666(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Synthon B.V. filed Critical Synthon B.V.
Publication of PL3206666T3 publication Critical patent/PL3206666T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid, pantothenic acid
    • A61K31/198—Alpha-aminoacids, e.g. alanine, edetic acids [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
PL15778927T 2014-10-16 2015-10-09 Ciekła kompozycja farmaceutyczna zawierająca pemetreksed PL3206666T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP14189222 2014-10-16
EP15778927.2A EP3206666B1 (en) 2014-10-16 2015-10-09 Liquid pharmaceutical composition comprising pemetrexed
PCT/EP2015/073385 WO2015193517A2 (en) 2014-10-16 2015-10-09 Liquid pharmaceutical composition comprising pemetrexed

Publications (1)

Publication Number Publication Date
PL3206666T3 true PL3206666T3 (pl) 2020-09-21

Family

ID=51844505

Family Applications (1)

Application Number Title Priority Date Filing Date
PL15778927T PL3206666T3 (pl) 2014-10-16 2015-10-09 Ciekła kompozycja farmaceutyczna zawierająca pemetreksed

Country Status (12)

Country Link
US (3) US20180235969A1 (pl)
EP (1) EP3206666B1 (pl)
EA (1) EA034559B1 (pl)
ES (1) ES2775582T3 (pl)
HR (1) HRP20200387T1 (pl)
HU (1) HUE048357T2 (pl)
LT (1) LT3206666T (pl)
PL (1) PL3206666T3 (pl)
PT (1) PT3206666T (pl)
RS (1) RS60183B1 (pl)
SI (1) SI3206666T1 (pl)
WO (1) WO2015193517A2 (pl)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017142556A1 (en) * 2016-02-19 2017-08-24 Feng-Jing Chen Pemetrexed formulations
US20170239250A1 (en) * 2016-02-19 2017-08-24 Eagle Pharmaceuticals, Inc. Pemetrexed formulations
JP6854710B2 (ja) * 2017-06-14 2021-04-07 日本化薬株式会社 ペメトレキセドを含有する注射用溶液製剤
JP2019094284A (ja) * 2017-11-21 2019-06-20 日本化薬株式会社 ペメトレキセドを含有する注射用溶液製剤
WO2020222151A1 (en) * 2019-05-01 2020-11-05 Intas Pharmaceuticals Ltd. A stable, ready to use aqueous pharmaceutical composition of pemetrexed
JP7282065B2 (ja) * 2020-10-05 2023-05-26 イーグル ファーマシューティカルズ， インコーポレイテッド ペメトレキセド製剤

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL96531A (en) 1989-12-11 1995-08-31 Univ Princeton History of Acid N- (Diomeric-H1-Pyrolo] D-2,3 [Pyrimidine-3-Ilacyl (-glutamic, preparation and pharmaceutical preparations containing them)
US6686365B2 (en) * 2000-02-04 2004-02-03 Eli Lilly And Company Pharmaceutical composition
NZ519727A (en) 2000-02-04 2004-04-30 Lilly Co Eli Pharmaceutical composition comprising pemetrexed together with monothioglycerol L-cysteine or thioglycolic acid
CN101081301A (zh) * 2006-05-29 2007-12-05 海南天源康泽医药科技有限公司 含有培美曲塞的药物组合物
CN100522173C (zh) 2006-07-28 2009-08-05 南京依诺维医药科技有限公司 含有培美曲塞的药物组合物
US9655898B2 (en) * 2010-07-28 2017-05-23 Eagle Pharmaceuticals, Inc. Pharmaceutical compositions containing pemetrexed having extended storage stability
KR101069128B1 (ko) 2011-03-10 2011-09-30 건일제약 주식회사 페메트렉시드 또는 그의 염을 포함하는 항산화제-비함유 주사용 용액 형태의 약학적 제제의 제조방법
US20150073000A1 (en) 2012-03-27 2015-03-12 Fresenius Kabi Oncology Limited Stable ready-to-use pharmaceutical composition of pemetrexed
EP2666463A1 (en) * 2012-05-21 2013-11-27 Synthon BV Stabilized liquid composition comprising pemetrexed
EP3210629A1 (en) * 2012-05-30 2017-08-30 Fresenius Kabi Oncology Ltd Pharmaceutical composition of pemetrexed
DE102012010774A1 (de) 2012-05-31 2013-12-05 Stada Arzneimittel Ag Pharmazeutische Pemetrexed-Lösung
ES2657944T3 (es) 2013-06-14 2018-03-07 Synthon B.V. Sal estable de arginina de pemetrexed y composiciones que la comprenden

Also Published As

Publication number Publication date
LT3206666T (lt) 2020-03-10
ES2775582T3 (es) 2020-07-27
WO2015193517A3 (en) 2016-03-10
EA034559B1 (ru) 2020-02-20
SI3206666T1 (sl) 2020-04-30
US20190105325A1 (en) 2019-04-11
HRP20200387T1 (hr) 2020-06-12
US20180235969A1 (en) 2018-08-23
US10272090B1 (en) 2019-04-30
US10188655B2 (en) 2019-01-29
WO2015193517A2 (en) 2015-12-23
HUE048357T2 (hu) 2020-08-28
EP3206666A2 (en) 2017-08-23
PT3206666T (pt) 2020-03-11
RS60183B1 (sr) 2020-06-30
EA201790788A1 (ru) 2017-08-31
EP3206666B1 (en) 2019-12-11
US20180271872A1 (en) 2018-09-27

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