PL306858A1 - Method of isolating recombination protein in biologically active form from a solution containing non-active protein - Google Patents

Method of isolating recombination protein in biologically active form from a solution containing non-active protein

Info

Publication number
PL306858A1
PL306858A1 PL93306858A PL30685893A PL306858A1 PL 306858 A1 PL306858 A1 PL 306858A1 PL 93306858 A PL93306858 A PL 93306858A PL 30685893 A PL30685893 A PL 30685893A PL 306858 A1 PL306858 A1 PL 306858A1
Authority
PL
Poland
Prior art keywords
protein
isolating
solution containing
containing non
biologically active
Prior art date
Application number
PL93306858A
Other languages
English (en)
Inventor
Eunkyu Lee
Doreen A Svihla
Ren-Der Yang
Original Assignee
Pitman Moore Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pitman Moore Inc filed Critical Pitman Moore Inc
Publication of PL306858A1 publication Critical patent/PL306858A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/113General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
    • C07K1/1133General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure by redox-reactions involving cystein/cystin side chains
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/61Growth hormone [GH], i.e. somatotropin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
PL93306858A 1992-07-02 1993-07-01 Method of isolating recombination protein in biologically active form from a solution containing non-active protein PL306858A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US90814692A 1992-07-02 1992-07-02

Publications (1)

Publication Number Publication Date
PL306858A1 true PL306858A1 (en) 1995-04-18

Family

ID=25425274

Family Applications (1)

Application Number Title Priority Date Filing Date
PL93306858A PL306858A1 (en) 1992-07-02 1993-07-01 Method of isolating recombination protein in biologically active form from a solution containing non-active protein

Country Status (7)

Country Link
EP (1) EP0650497A1 (fr)
CN (1) CN1039330C (fr)
AU (1) AU4665193A (fr)
PL (1) PL306858A1 (fr)
TW (1) TW235965B (fr)
WO (1) WO1994001453A1 (fr)
ZA (1) ZA934780B (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7153943B2 (en) 1997-07-14 2006-12-26 Bolder Biotechnology, Inc. Derivatives of growth hormone and related proteins, and methods of use thereof
US20080076706A1 (en) 1997-07-14 2008-03-27 Bolder Biotechnology, Inc. Derivatives of Growth Hormone and Related Proteins, and Methods of Use Thereof
US7270809B2 (en) 1997-07-14 2007-09-18 Bolder Biotechnology, Inc. Cysteine variants of alpha interferon-2
US6753165B1 (en) 1999-01-14 2004-06-22 Bolder Biotechnology, Inc. Methods for making proteins containing free cysteine residues
EP1012184B1 (fr) 1997-07-14 2007-10-10 Bolder Biotechnology, Inc. Derives d'hormone de croissance et proteines associees
AU739394B2 (en) * 1998-08-27 2001-10-11 Lg Chemical Limited Process for the preparation of active somatotropin from inclusion bodies
US8288126B2 (en) 1999-01-14 2012-10-16 Bolder Biotechnology, Inc. Methods for making proteins containing free cysteine residues
IL152804A0 (en) * 2000-05-16 2003-06-24 Bolder Biotechnology Inc Methods for refolding proteins containing free cysteine residues
US8617531B2 (en) 2006-12-14 2013-12-31 Bolder Biotechnology, Inc. Methods of making proteins and peptides containing a single free cysteine
WO2017019776A1 (fr) * 2015-07-27 2017-02-02 Purdue Research Foundation Procédés de repliement en tandem pour améliorer le rendement de repliement des protéines
EP3344651B1 (fr) 2015-09-02 2022-03-02 Merck Sharp & Dohme Corp. Procédé d'obtention d'insuline avec liaisons disulfure correctement formées
CN111610324B (zh) * 2020-06-06 2022-10-14 北京均大检测科技有限公司 一种ripa裂解液及其制备方法
CN114878728A (zh) * 2022-05-06 2022-08-09 浙江大学 一种新型的抗体肽图检测还原方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4931543A (en) * 1987-05-11 1990-06-05 Cetus Corporation Process for recovering microbially produced interleukin-2
EP0301835A1 (fr) * 1987-07-29 1989-02-01 Schering Biotech Corporation Purification de l'interleukine-4 humaine exprimée dans Escherickia coli
JPH01132598A (ja) * 1987-10-14 1989-05-25 Pitman Moore Inc 変性剤溶液中に含まれる組換え蛋白質における分子内ジスルフィド結合の生成を促進する方法
US5064943A (en) * 1988-12-16 1991-11-12 American Cyanamid Company Method for solubilization and naturation of somatotropin
ES2119779T3 (es) * 1990-09-05 1998-10-16 Southern Cross Biotech Pty Ltd Solubilizacion de proteinas en formas activas.

Also Published As

Publication number Publication date
EP0650497A1 (fr) 1995-05-03
CN1039330C (zh) 1998-07-29
CN1083071A (zh) 1994-03-02
AU4665193A (en) 1994-01-31
TW235965B (fr) 1994-12-11
WO1994001453A1 (fr) 1994-01-20
ZA934780B (en) 1994-03-17

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