PL306858A1 - Method of isolating recombination protein in biologically active form from a solution containing non-active protein - Google Patents
Method of isolating recombination protein in biologically active form from a solution containing non-active proteinInfo
- Publication number
- PL306858A1 PL306858A1 PL93306858A PL30685893A PL306858A1 PL 306858 A1 PL306858 A1 PL 306858A1 PL 93306858 A PL93306858 A PL 93306858A PL 30685893 A PL30685893 A PL 30685893A PL 306858 A1 PL306858 A1 PL 306858A1
- Authority
- PL
- Poland
- Prior art keywords
- protein
- isolating
- solution containing
- containing non
- biologically active
- Prior art date
Links
- 102000004169 proteins and genes Human genes 0.000 title 2
- 108090000623 proteins and genes Proteins 0.000 title 2
- 238000000034 method Methods 0.000 title 1
- 238000005215 recombination Methods 0.000 title 1
- 230000006798 recombination Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
- C07K1/1133—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure by redox-reactions involving cystein/cystin side chains
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/61—Growth hormone [GH], i.e. somatotropin
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Endocrinology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US90814692A | 1992-07-02 | 1992-07-02 |
Publications (1)
Publication Number | Publication Date |
---|---|
PL306858A1 true PL306858A1 (en) | 1995-04-18 |
Family
ID=25425274
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL93306858A PL306858A1 (en) | 1992-07-02 | 1993-07-01 | Method of isolating recombination protein in biologically active form from a solution containing non-active protein |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP0650497A1 (fr) |
CN (1) | CN1039330C (fr) |
AU (1) | AU4665193A (fr) |
PL (1) | PL306858A1 (fr) |
TW (1) | TW235965B (fr) |
WO (1) | WO1994001453A1 (fr) |
ZA (1) | ZA934780B (fr) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7153943B2 (en) | 1997-07-14 | 2006-12-26 | Bolder Biotechnology, Inc. | Derivatives of growth hormone and related proteins, and methods of use thereof |
US20080076706A1 (en) | 1997-07-14 | 2008-03-27 | Bolder Biotechnology, Inc. | Derivatives of Growth Hormone and Related Proteins, and Methods of Use Thereof |
US7270809B2 (en) | 1997-07-14 | 2007-09-18 | Bolder Biotechnology, Inc. | Cysteine variants of alpha interferon-2 |
US6753165B1 (en) | 1999-01-14 | 2004-06-22 | Bolder Biotechnology, Inc. | Methods for making proteins containing free cysteine residues |
EP1012184B1 (fr) | 1997-07-14 | 2007-10-10 | Bolder Biotechnology, Inc. | Derives d'hormone de croissance et proteines associees |
AU739394B2 (en) * | 1998-08-27 | 2001-10-11 | Lg Chemical Limited | Process for the preparation of active somatotropin from inclusion bodies |
US8288126B2 (en) | 1999-01-14 | 2012-10-16 | Bolder Biotechnology, Inc. | Methods for making proteins containing free cysteine residues |
IL152804A0 (en) * | 2000-05-16 | 2003-06-24 | Bolder Biotechnology Inc | Methods for refolding proteins containing free cysteine residues |
US8617531B2 (en) | 2006-12-14 | 2013-12-31 | Bolder Biotechnology, Inc. | Methods of making proteins and peptides containing a single free cysteine |
WO2017019776A1 (fr) * | 2015-07-27 | 2017-02-02 | Purdue Research Foundation | Procédés de repliement en tandem pour améliorer le rendement de repliement des protéines |
EP3344651B1 (fr) | 2015-09-02 | 2022-03-02 | Merck Sharp & Dohme Corp. | Procédé d'obtention d'insuline avec liaisons disulfure correctement formées |
CN111610324B (zh) * | 2020-06-06 | 2022-10-14 | 北京均大检测科技有限公司 | 一种ripa裂解液及其制备方法 |
CN114878728A (zh) * | 2022-05-06 | 2022-08-09 | 浙江大学 | 一种新型的抗体肽图检测还原方法 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4931543A (en) * | 1987-05-11 | 1990-06-05 | Cetus Corporation | Process for recovering microbially produced interleukin-2 |
EP0301835A1 (fr) * | 1987-07-29 | 1989-02-01 | Schering Biotech Corporation | Purification de l'interleukine-4 humaine exprimée dans Escherickia coli |
JPH01132598A (ja) * | 1987-10-14 | 1989-05-25 | Pitman Moore Inc | 変性剤溶液中に含まれる組換え蛋白質における分子内ジスルフィド結合の生成を促進する方法 |
US5064943A (en) * | 1988-12-16 | 1991-11-12 | American Cyanamid Company | Method for solubilization and naturation of somatotropin |
ES2119779T3 (es) * | 1990-09-05 | 1998-10-16 | Southern Cross Biotech Pty Ltd | Solubilizacion de proteinas en formas activas. |
-
1993
- 1993-07-01 AU AU46651/93A patent/AU4665193A/en not_active Abandoned
- 1993-07-01 PL PL93306858A patent/PL306858A1/xx unknown
- 1993-07-01 EP EP93916974A patent/EP0650497A1/fr not_active Ceased
- 1993-07-01 CN CN93108052A patent/CN1039330C/zh not_active Expired - Fee Related
- 1993-07-01 WO PCT/US1993/006351 patent/WO1994001453A1/fr not_active Application Discontinuation
- 1993-07-02 ZA ZA934780A patent/ZA934780B/xx unknown
- 1993-07-02 TW TW082105281A patent/TW235965B/zh active
Also Published As
Publication number | Publication date |
---|---|
EP0650497A1 (fr) | 1995-05-03 |
CN1039330C (zh) | 1998-07-29 |
CN1083071A (zh) | 1994-03-02 |
AU4665193A (en) | 1994-01-31 |
TW235965B (fr) | 1994-12-11 |
WO1994001453A1 (fr) | 1994-01-20 |
ZA934780B (en) | 1994-03-17 |
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