PL3052234T3 - Urządzenie mikroprzepływowe oraz sposoby - Google Patents

Urządzenie mikroprzepływowe oraz sposoby

Info

Publication number
PL3052234T3
PL3052234T3 PL14777351.9T PL14777351T PL3052234T3 PL 3052234 T3 PL3052234 T3 PL 3052234T3 PL 14777351 T PL14777351 T PL 14777351T PL 3052234 T3 PL3052234 T3 PL 3052234T3
Authority
PL
Poland
Prior art keywords
methods
microfluidic device
microfluidic
Prior art date
Application number
PL14777351.9T
Other languages
English (en)
Inventor
Göran Stemme
Gabriel LENK
Olof Beck
Niclas ROXHED
Original Assignee
Capitainer Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Capitainer Ab filed Critical Capitainer Ab
Publication of PL3052234T3 publication Critical patent/PL3052234T3/pl

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502738—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by integrated valves
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/50273—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means or forces applied to move the fluids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502753—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by bulk separation arrangements on lab-on-a-chip devices, e.g. for filtration or centrifugation
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K99/00—Subject matter not provided for in other groups of this subclass
    • F16K99/0001—Microvalves
    • F16K99/0003—Constructional types of microvalves; Details of the cutting-off member
    • F16K99/003—Valves for single use only
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K99/00—Subject matter not provided for in other groups of this subclass
    • F16K99/0001—Microvalves
    • F16K99/0034—Operating means specially adapted for microvalves
    • F16K99/0055—Operating means specially adapted for microvalves actuated by fluids
    • F16K99/0057—Operating means specially adapted for microvalves actuated by fluids the fluid being the circulating fluid itself, e.g. check valves
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0605—Metering of fluids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/069—Absorbents; Gels to retain a fluid
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0832—Geometry, shape and general structure cylindrical, tube shaped
    • B01L2300/0838—Capillaries
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0864—Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0887—Laminated structure
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/12—Specific details about materials
    • B01L2300/126—Paper
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/16—Surface properties and coatings
    • B01L2300/161—Control and use of surface tension forces, e.g. hydrophobic, hydrophilic
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0406—Moving fluids with specific forces or mechanical means specific forces capillary forces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0677—Valves, specific forms thereof phase change valves; Meltable, freezing, dissolvable plugs; Destructible barriers
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K99/00—Subject matter not provided for in other groups of this subclass
    • F16K2099/0082—Microvalves adapted for a particular use
    • F16K2099/0084—Chemistry or biology, e.g. "lab-on-a-chip" technology
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K99/00—Subject matter not provided for in other groups of this subclass
    • F16K2099/0082—Microvalves adapted for a particular use
    • F16K2099/0086—Medical applications

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mechanical Engineering (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
PL14777351.9T 2013-09-30 2014-09-30 Urządzenie mikroprzepływowe oraz sposoby PL3052234T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE1300623 2013-09-30
PCT/EP2014/070937 WO2015044454A2 (en) 2013-09-30 2014-09-30 A microfluidic device, use and methods

Publications (1)

Publication Number Publication Date
PL3052234T3 true PL3052234T3 (pl) 2024-08-05

Family

ID=51628149

Family Applications (1)

Application Number Title Priority Date Filing Date
PL14777351.9T PL3052234T3 (pl) 2013-09-30 2014-09-30 Urządzenie mikroprzepływowe oraz sposoby

Country Status (6)

Country Link
US (1) US10220389B2 (pl)
EP (1) EP3052234B8 (pl)
CN (1) CN105848783B (pl)
ES (1) ES2984374T3 (pl)
PL (1) PL3052234T3 (pl)
WO (1) WO2015044454A2 (pl)

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US11305236B2 (en) 2014-06-13 2022-04-19 Gattaco Inc. Surface tension driven filtration
WO2015191406A1 (en) * 2014-06-13 2015-12-17 Mcneely Michael Ryan Capillary pressure re-set mechanism and applications
DE102015007642A1 (de) * 2015-06-17 2016-12-22 Sarstedt Ag & Co. Verfahren und Vorrichtung zum Bereitstellen von eine getrocknete Flüssigkeitsmenge, insbesondere Blut, aufweisenden, saugfähigen Probenträgern
ES2863594T3 (es) 2015-06-20 2021-10-11 Capitainer Ab Dispositivo microfluídico de separación de plasma
WO2017015243A1 (en) 2015-07-21 2017-01-26 Mcneely Michael Ryan Automatic plasma separation and metering
CN105772121A (zh) * 2016-03-09 2016-07-20 苏州露水生物技术有限公司 微流控技术在血液中分离中的应用
AU2017202369C1 (en) 2016-04-11 2022-09-29 National Research Council Of Canada Patterned Film for Forming Fluid-Filled Blister, Microfluidic Blister, and Kit and Method of Forming
CN105964315B (zh) * 2016-05-23 2017-12-22 杭州霆科生物科技有限公司 一种多级自控的微流控芯片
WO2018002249A1 (de) 2016-06-30 2018-01-04 Sarstedt Aktiengesellschaft & Co. Kg Vorrichtung zum bereitstellen von eine getrocknete flüssigkeitsmenge, insbesondere blut, aufweisenden, saugfähigen probenträgern
CN110214047A (zh) * 2017-01-18 2019-09-06 精密纳米系统有限公司 微流体混合器中的低复杂性流量控制
JP7372150B2 (ja) 2017-02-02 2023-10-31 ユニバーシティ オブ メリーランド，カレッジ パーク 堅牢なマイクロ流体試料デジタル化のためのトラップアレイ
CN115634721A (zh) * 2017-02-16 2023-01-24 Essenlix 公司 基于qmax卡的测定装置和方法
US12326445B2 (en) * 2018-08-31 2025-06-10 National Institute Of Advanced Industrial Science And Technology Assay device
US10717080B2 (en) * 2018-09-05 2020-07-21 Paratus Diagnostics, LLC Systems and method for metering and timing of fluid flow in a point-of-care diagnostic cartridge
CN113167785B (zh) * 2018-09-06 2024-09-03 卡皮台内尔公司 微流体装置
CN109158136B (zh) * 2018-10-19 2023-10-13 上海快灵生物工程有限公司 一种微孔膜截留的微流体芯片及其溶液流路控制的方法
CN113226551A (zh) * 2018-11-09 2021-08-06 江苏集萃微纳自动化系统与装备技术研究所有限公司 纳米纤化纤维素纸基微流体装置
NL2022085B1 (en) * 2018-11-28 2020-06-25 Mimetas B V Device for assessing mechanical strain induced in or by cells
CN110508337B (zh) * 2019-03-27 2022-08-30 广州万孚生物技术股份有限公司 体外检测装置及其上样机构
US11485945B2 (en) * 2020-09-17 2022-11-01 Intelligent Virus Imaging Inc Autonomous microfluidic device for sample preparation
US11484882B2 (en) * 2020-09-17 2022-11-01 Intelligent Virus Imaging Inc. Autonomous microfluidic device for sample preparation
CN113101990B (zh) * 2021-04-13 2022-06-21 广西大学 一种用于微流体集成芯片中流体试剂储存和自触发并延时释放的方法
KR20240026458A (ko) * 2021-06-29 2024-02-28 캐피테이너 아베 미세유체 장치
WO2023277773A1 (en) 2021-06-29 2023-01-05 Capitainer Ab Microfluidic devices
CN115074246A (zh) * 2022-07-14 2022-09-20 上海交通大学 具有可溶临时屏障的微流控器官芯片及其制备方法
CN115245847B (zh) * 2022-08-09 2024-04-19 东南大学 一种基于特斯拉阀的微混合芯片
WO2025003467A1 (en) 2023-06-29 2025-01-02 Katholieke Universiteit Leuven Timed valve
CN119334693B (zh) * 2023-07-18 2025-11-04 深圳华大智造科技股份有限公司 干血斑定量分装装置和方法

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Also Published As

Publication number Publication date
US10220389B2 (en) 2019-03-05
WO2015044454A3 (en) 2015-05-21
EP3052234A2 (en) 2016-08-10
EP3052234B1 (en) 2024-05-01
EP3052234B8 (en) 2024-06-19
CN105848783B (zh) 2017-12-01
ES2984374T3 (es) 2024-10-29
CN105848783A (zh) 2016-08-10
WO2015044454A2 (en) 2015-04-02
US20160279634A1 (en) 2016-09-29
EP3052234C0 (en) 2024-05-01

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