PL2941429T3 - Fluoro-9-metylo-β-karboliny - Google Patents

Fluoro-9-metylo-β-karboliny

Info

Publication number
PL2941429T3
PL2941429T3 PL14781129T PL14781129T PL2941429T3 PL 2941429 T3 PL2941429 T3 PL 2941429T3 PL 14781129 T PL14781129 T PL 14781129T PL 14781129 T PL14781129 T PL 14781129T PL 2941429 T3 PL2941429 T3 PL 2941429T3
Authority
PL
Poland
Prior art keywords
carbolines
fluor
beta
methyl
Prior art date
Application number
PL14781129T
Other languages
English (en)
Inventor
Hans Rommelspacher
Christoph Enzensperger
Original Assignee
Audiocure Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Audiocure Pharma Gmbh filed Critical Audiocure Pharma Gmbh
Publication of PL2941429T3 publication Critical patent/PL2941429T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0046—Ear
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
PL14781129T 2013-09-29 2014-09-29 Fluoro-9-metylo-β-karboliny PL2941429T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP13186560.2A EP2853533A1 (de) 2013-09-29 2013-09-29 6-Fluor-9-methyl-ß-carbolin
EP14781129.3A EP2941429B1 (de) 2013-09-29 2014-09-29 Fluor-9-methyl-beta-carboline

Publications (1)

Publication Number Publication Date
PL2941429T3 true PL2941429T3 (pl) 2017-07-31

Family

ID=49237130

Family Applications (1)

Application Number Title Priority Date Filing Date
PL14781129T PL2941429T3 (pl) 2013-09-29 2014-09-29 Fluoro-9-metylo-β-karboliny

Country Status (13)

Country Link
US (1) US9630964B2 (pl)
EP (2) EP2853533A1 (pl)
JP (1) JP6378344B2 (pl)
KR (1) KR101879110B1 (pl)
CN (1) CN105579455B (pl)
AU (1) AU2014326708B2 (pl)
CA (1) CA2924755C (pl)
DK (1) DK2941429T3 (pl)
ES (1) ES2622980T3 (pl)
HU (1) HUE033997T2 (pl)
PL (1) PL2941429T3 (pl)
RU (1) RU2642785C2 (pl)
WO (1) WO2015044434A2 (pl)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20190024983A (ko) 2016-06-29 2019-03-08 오토노미, 인코포레이티드 트리글리세라이드 귀 제제 및 이의 용도
CN110337291A (zh) * 2016-12-16 2019-10-15 帕珀莱恩医疗公司 治疗耳蜗突触病变的方法
EP3772515A1 (en) * 2019-08-09 2021-02-10 Audiocure Pharma GmbH Stable polymorphic form of 6-fluoro-9-methyl-9h-ss-carboline and uses thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040038970A1 (en) 1998-06-12 2004-02-26 Societe De Conseils De Recherches Etd' Application Scientifiques, S.A.S. A Paris, France Corp. Beta-carboline compounds
DE102007009264A1 (de) 2007-02-26 2008-08-28 Ellneuroxx Ltd. 9-Alkyl-ß-Carboline zur Behandlung von neurodegenerativen Erkrankungen
BRPI0910850B1 (pt) * 2008-04-21 2022-06-14 Otonomy, Inc. Composição intratimpânica compreendendo fator neurotrófico de crescimento derivado do cérebro (bdnf) para o tratamento ou prevenção da perda auditiva
BR112012015967B1 (pt) * 2009-12-28 2019-08-27 Audiocure Pharma Gmbh uso de compostos de fórmula geral (i) e composição farmacêutica

Also Published As

Publication number Publication date
CA2924755A1 (en) 2015-04-02
CA2924755C (en) 2019-09-17
DK2941429T3 (en) 2017-04-10
HK1222844A1 (zh) 2017-07-14
CN105579455B (zh) 2017-07-28
WO2015044434A2 (de) 2015-04-02
HUE033997T2 (en) 2018-01-29
AU2014326708B2 (en) 2017-05-25
ES2622980T3 (es) 2017-07-10
WO2015044434A9 (de) 2016-08-25
WO2015044434A3 (de) 2015-05-21
US20160214981A1 (en) 2016-07-28
RU2016116808A (ru) 2017-11-02
KR20160065929A (ko) 2016-06-09
EP2941429B1 (de) 2017-01-25
CN105579455A (zh) 2016-05-11
US9630964B2 (en) 2017-04-25
AU2014326708A1 (en) 2016-04-28
JP6378344B2 (ja) 2018-08-22
RU2642785C2 (ru) 2018-01-26
EP2941429A2 (de) 2015-11-11
EP2853533A1 (de) 2015-04-01
JP2016533389A (ja) 2016-10-27
KR101879110B1 (ko) 2018-07-16

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