PL2831110T3 - Terapia anty-EMP2 zmniejsza ilość rakowych komórek macierzystych - Google Patents

Terapia anty-EMP2 zmniejsza ilość rakowych komórek macierzystych

Info

Publication number
PL2831110T3
PL2831110T3 PL13770310T PL13770310T PL2831110T3 PL 2831110 T3 PL2831110 T3 PL 2831110T3 PL 13770310 T PL13770310 T PL 13770310T PL 13770310 T PL13770310 T PL 13770310T PL 2831110 T3 PL2831110 T3 PL 2831110T3
Authority
PL
Poland
Prior art keywords
stem cells
cancer stem
therapy reduces
emp2 therapy
emp2
Prior art date
Application number
PL13770310T
Other languages
English (en)
Inventor
Madhuri Wadehra
Jonathan Braun
Lynn K. Gordon
Gary S. Lazar
Original Assignee
The Regents Of The University Of California
Paganini Biopharma, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Regents Of The University Of California, Paganini Biopharma, Inc. filed Critical The Regents Of The University Of California
Publication of PL2831110T3 publication Critical patent/PL2831110T3/pl

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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    • A61K47/6869—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a determinant of a tumour cell the tumour determinant being from a cell of the reproductive system: ovaria, uterus, testes, prostate
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    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07K2317/00—Immunoglobulins specific features
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
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PL13770310T 2012-03-30 2013-03-14 Terapia anty-EMP2 zmniejsza ilość rakowych komórek macierzystych PL2831110T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261617996P 2012-03-30 2012-03-30
PCT/US2013/031542 WO2013148263A1 (en) 2012-03-30 2013-03-14 Anti-emp2 therapy reduces cancer stem cells
EP13770310.4A EP2831110B1 (en) 2012-03-30 2013-03-14 Anti-emp2 therapy reduces cancer stem cells

Publications (1)

Publication Number Publication Date
PL2831110T3 true PL2831110T3 (pl) 2018-11-30

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PL13770310T PL2831110T3 (pl) 2012-03-30 2013-03-14 Terapia anty-EMP2 zmniejsza ilość rakowych komórek macierzystych

Country Status (12)

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US (2) US20150329621A1 (pl)
EP (1) EP2831110B1 (pl)
JP (1) JP2015514708A (pl)
AU (1) AU2013203396C1 (pl)
CA (1) CA2868791A1 (pl)
DK (1) DK2831110T3 (pl)
ES (1) ES2689269T3 (pl)
HU (1) HUE039389T2 (pl)
PL (1) PL2831110T3 (pl)
PT (1) PT2831110T (pl)
TR (1) TR201811308T4 (pl)
WO (1) WO2013148263A1 (pl)

Families Citing this family (8)

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Publication number Priority date Publication date Assignee Title
WO2013155346A1 (en) 2012-04-11 2013-10-17 The Regents Of The University Of California Diagnostic tools for response to 6-thiopurine therapy
PH12019501393B1 (en) 2013-08-01 2022-09-07 Five Prime Therapeutics Inc Afucosylated anti-fgfr2iiib antibodies
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AU2013203396A1 (en) 2013-10-17
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