PL2774910T3 - Enancjomery 2-hydroksy pochodnych kwasów tłuszczowych - Google Patents

Enancjomery 2-hydroksy pochodnych kwasów tłuszczowych

Info

Publication number
PL2774910T3
PL2774910T3 PL12838506T PL12838506T PL2774910T3 PL 2774910 T3 PL2774910 T3 PL 2774910T3 PL 12838506 T PL12838506 T PL 12838506T PL 12838506 T PL12838506 T PL 12838506T PL 2774910 T3 PL2774910 T3 PL 2774910T3
Authority
PL
Poland
Prior art keywords
enantiomers
fatty acids
hydroxy derivatives
hydroxy
derivatives
Prior art date
Application number
PL12838506T
Other languages
English (en)
Inventor
Ruiz Pablo Vicente Escribá
María Laura Martín
Salvà María Antònia Noguera
Xaubet Xavier Busquets
Jiménez David López
Aizpitarte Maitane Ibarguren
Salvador José Javier Soto
Astiz Miguel Yus
Original Assignee
Universitat De Les Illes Balears
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universitat De Les Illes Balears filed Critical Universitat De Les Illes Balears
Publication of PL2774910T3 publication Critical patent/PL2774910T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/20Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/201Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having one or two double bonds, e.g. oleic, linoleic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42Separation; Purification; Stabilisation; Use of additives
    • C07C51/487Separation; Purification; Stabilisation; Use of additives by treatment giving rise to chemical modification
    • C07C51/493Separation; Purification; Stabilisation; Use of additives by treatment giving rise to chemical modification whereby carboxylic acid esters are formed
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/42Unsaturated compounds containing hydroxy or O-metal groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07Optical isomers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Emergency Medicine (AREA)
  • Vascular Medicine (AREA)
  • Oncology (AREA)
  • Endocrinology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Urology & Nephrology (AREA)
  • Epidemiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
PL12838506T 2011-10-07 2012-10-08 Enancjomery 2-hydroksy pochodnych kwasów tłuszczowych PL2774910T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
ES201131622A ES2401629B1 (es) 2011-10-07 2011-10-07 Enantiómeros de 2-hidroxiderivados de ácidos grasos y su uso como medicamentos.
US201261610762P 2012-03-14 2012-03-14
EP12838506.9A EP2774910B1 (en) 2011-10-07 2012-10-08 Enantiomers of 2-hydroxy derivatives of fatty acids
PCT/ES2012/070697 WO2013050644A1 (es) 2011-10-07 2012-10-08 Enantiómeros de 2-hidroxiderivados de ácidos grasos

Publications (1)

Publication Number Publication Date
PL2774910T3 true PL2774910T3 (pl) 2018-03-30

Family

ID=48043212

Family Applications (1)

Application Number Title Priority Date Filing Date
PL12838506T PL2774910T3 (pl) 2011-10-07 2012-10-08 Enancjomery 2-hydroksy pochodnych kwasów tłuszczowych

Country Status (12)

Country Link
US (1) US9359281B2 (pl)
EP (2) EP3287437B1 (pl)
JP (1) JP2014530806A (pl)
CN (1) CN104321300A (pl)
DK (1) DK2774910T3 (pl)
ES (3) ES2401629B1 (pl)
HU (1) HUE035430T2 (pl)
IN (1) IN2014CN03111A (pl)
PL (1) PL2774910T3 (pl)
PT (1) PT2774910T (pl)
RU (2) RU2637937C2 (pl)
WO (1) WO2013050644A1 (pl)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2345241B1 (es) * 2009-03-16 2011-09-08 Lipopharma Therapeutics Uso de 2-hidroxiderivados de acidos grasos poliinsaturados como medicamentos.
ES2731251T3 (es) * 2014-10-21 2019-11-14 Univ Illes Balears Compuestos de 2-hidroxi-triacilglicerol para uso en el tratamiento de una enfermedad
US11260042B2 (en) * 2017-05-16 2022-03-01 Ability Pharmaceuticals S.L. Pharmaceutical combination for the treatment of cancer
WO2019099664A1 (en) * 2017-11-16 2019-05-23 The Research Foundation For The State University Of New York Use of 2-hydroxyoleic acid for the treatment of systemic lupus erythematosus and other immune pathologies
BR112022015172A2 (pt) * 2020-01-29 2022-10-11 Univ Illes Balears Metabólitos de ácidos graxos alfa-hidroxilados, usos médicos dos mesmos e uso como biomarcadores
ES2846824B2 (es) * 2020-01-29 2022-01-19 Univ Illes Balears Profarmacos de acidos grasos poliinsaturados y usos medicos de los mismos
ES2911474B2 (es) * 2020-11-17 2023-02-06 Univ Illes Balears Profarmacos de acidos grasos monoinsaturados y sus metabolitos: usos medicos y como biomarcadores
AU2021220258A1 (en) * 2020-02-10 2022-06-30 Ability Pharmaceuticals S.L. A pharmaceutical combination for the treatment of a cancer

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2235541C2 (ru) * 1994-10-04 2004-09-10 Эмори Юниверсити Лечение атеросклероза и других сердечно-сосудистых и воспалительных заболеваний
AUPR547601A0 (en) * 2001-06-05 2001-06-28 Carcraft Qld Pty Ltd Tab with writing surface
ES2186576B1 (es) * 2001-10-11 2004-09-16 Universitat De Les Illes Balears Acido 2-hidroxioleico para utilizar como medicamento.
ES2342997B1 (es) * 2008-12-09 2011-06-06 Universitat De Les Illes Balears Alpha derivados de acidos grasos cis-monoinsaturados para ser usados como medicamento.
ES2345241B1 (es) * 2009-03-16 2011-09-08 Lipopharma Therapeutics Uso de 2-hidroxiderivados de acidos grasos poliinsaturados como medicamentos.

Also Published As

Publication number Publication date
PT2774910T (pt) 2018-01-03
IN2014CN03111A (pl) 2015-07-03
EP2774910A4 (en) 2015-02-25
CN104321300A (zh) 2015-01-28
EP2774910B1 (en) 2017-09-27
US9359281B2 (en) 2016-06-07
DK2774910T3 (en) 2018-01-08
ES2773784T3 (es) 2020-07-14
RU2017141446A3 (pl) 2019-02-13
RU2637937C2 (ru) 2017-12-08
RU2687967C2 (ru) 2019-05-17
JP2014530806A (ja) 2014-11-20
EP3287437A1 (en) 2018-02-28
ES2401629A1 (es) 2013-04-23
ES2653675T3 (es) 2018-02-08
US20140288176A1 (en) 2014-09-25
RU2017141446A (ru) 2019-02-13
WO2013050644A1 (es) 2013-04-11
RU2014118123A (ru) 2015-11-20
EP2774910A1 (en) 2014-09-10
ES2401629B1 (es) 2014-03-04
HUE035430T2 (en) 2018-05-02
EP3287437B1 (en) 2019-12-11

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