PL2611776T3 - Sposób wytwarzania pośredniego związku do syntezy leku - Google Patents

Sposób wytwarzania pośredniego związku do syntezy leku

Info

Publication number
PL2611776T3
PL2611776T3 PL11822081T PL11822081T PL2611776T3 PL 2611776 T3 PL2611776 T3 PL 2611776T3 PL 11822081 T PL11822081 T PL 11822081T PL 11822081 T PL11822081 T PL 11822081T PL 2611776 T3 PL2611776 T3 PL 2611776T3
Authority
PL
Poland
Prior art keywords
production method
intermediate compound
synthesizing
medicament
synthesizing medicament
Prior art date
Application number
PL11822081T
Other languages
English (en)
Inventor
Bong Chan Kim
Kyu Young Kim
Hee Bong Lee
Ji Eun An
Kyu Woong Lee
Original Assignee
Lg Life Sciences Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lg Life Sciences Ltd filed Critical Lg Life Sciences Ltd
Publication of PL2611776T3 publication Critical patent/PL2611776T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/74Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/74Oxygen atoms
    • C07D211/76Oxygen atoms attached in position 2 or 6
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/45Non condensed piperidines, e.g. piperocaine having oxo groups directly attached to the heterocyclic ring, e.g. cycloheximide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
PL11822081T 2010-09-03 2011-08-25 Sposób wytwarzania pośredniego związku do syntezy leku PL2611776T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR20100086619 2010-09-03
EP11822081.3A EP2611776B1 (en) 2010-09-03 2011-08-25 Production method of intermediate compound for synthesizing medicament

Publications (1)

Publication Number Publication Date
PL2611776T3 true PL2611776T3 (pl) 2017-06-30

Family

ID=45023417

Family Applications (1)

Application Number Title Priority Date Filing Date
PL11822081T PL2611776T3 (pl) 2010-09-03 2011-08-25 Sposób wytwarzania pośredniego związku do syntezy leku

Country Status (32)

Country Link
US (1) US8741927B2 (pl)
EP (1) EP2611776B1 (pl)
JP (1) JP5705985B2 (pl)
KR (1) KR101378984B1 (pl)
CN (1) CN103080088B (pl)
AP (1) AP3270A (pl)
AR (1) AR082881A1 (pl)
AU (1) AU2011296767B2 (pl)
BR (1) BR112013004988B1 (pl)
CA (1) CA2810393C (pl)
CL (1) CL2013000589A1 (pl)
CO (1) CO6700826A2 (pl)
DK (1) DK2611776T3 (pl)
EA (1) EA022500B1 (pl)
EC (1) ECSP13012471A (pl)
ES (1) ES2607089T3 (pl)
HK (1) HK1184787A1 (pl)
HU (1) HUE032484T2 (pl)
IL (1) IL224954B (pl)
MA (1) MA34490B1 (pl)
MX (1) MX2013002277A (pl)
MY (1) MY157423A (pl)
NZ (1) NZ607694A (pl)
PE (1) PE20131128A1 (pl)
PL (1) PL2611776T3 (pl)
PT (1) PT2611776T (pl)
SG (1) SG188329A1 (pl)
SI (1) SI2611776T1 (pl)
TW (1) TWI438188B (pl)
UA (1) UA107721C2 (pl)
UY (1) UY33589A (pl)
WO (1) WO2012030106A2 (pl)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2995612A1 (en) * 2014-09-12 2016-03-16 Université de Strasbourg Novel non-natural amino acids, their process of preparation and uses thereof
KR102068754B1 (ko) * 2017-04-20 2020-01-21 주식회사 엘지화학 의약품 합성용 중간체 화합물의 제조 방법
RU2742765C1 (ru) * 2017-09-28 2021-02-10 ЭлДжи КЕМ, ЛТД. Способ получения промежуточного соединения для синтеза лекарственного средства
MX2020003543A (es) * 2017-09-28 2020-07-29 Lg Chemical Ltd Metodo de produccion de un compuesto intermediario para sintetizar un medicamento.
CN111247127B (zh) * 2017-11-16 2024-02-06 株式会社Lg化学 用于合成药物的中间体化合物的生产方法
WO2019098551A1 (ko) * 2017-11-16 2019-05-23 주식회사 엘지화학 의약품 합성용 중간체 화합물의 제조 방법
CN113861061A (zh) * 2021-10-25 2021-12-31 成都市科隆化学品有限公司 一种不含无机铵盐的氨基酸酰胺盐酸盐及其合成方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4456768A (en) * 1980-10-08 1984-06-26 The University Of Chicago Chemical synthesis
US5556982A (en) 1985-01-14 1996-09-17 Neorx Corporation Metal radionuclide labeled proteins for diagnosis and therapy
DE3705272A1 (de) 1987-02-19 1988-09-01 Basf Ag Verfahren zur reduktion von mono- und dicarbonsaeuren
US5417023A (en) * 1993-12-27 1995-05-23 Mandish; Theodore O. Building panel apparatus and method
IL151018A0 (en) * 2000-03-17 2003-02-12 Bristol Myers Squibb Pharma Co Beta-amino acid derivatives as inhibitors of matrix metalloproteases and tnf-alpha
TWI357902B (en) * 2005-04-01 2012-02-11 Lg Life Science Ltd Dipeptidyl peptidase-iv inhibiting compounds, meth
CA2660397A1 (en) * 2006-08-09 2008-02-21 Smithkline Beecham Corporation Pyrrolidinone anilines as progesterone receptor modulators
KR20080071476A (ko) * 2007-01-30 2008-08-04 주식회사 엘지생명과학 신규한 디펩티딜 펩티데이즈 iv(dpp-iv) 저해제
AU2008341352B2 (en) * 2007-12-21 2013-08-01 Lg Chem, Ltd. Dipeptidyl peptidase-IV inhibiting compounds, methods of preparing the same, and pharmaceutical compositions containing the same as active agent

Also Published As

Publication number Publication date
BR112013004988B1 (pt) 2020-07-28
US8741927B2 (en) 2014-06-03
EP2611776A2 (en) 2013-07-10
DK2611776T3 (en) 2017-01-09
MX2013002277A (es) 2013-05-22
CN103080088A (zh) 2013-05-01
AR082881A1 (es) 2013-01-16
TWI438188B (zh) 2014-05-21
HK1184787A1 (en) 2014-01-30
TW201213297A (en) 2012-04-01
HUE032484T2 (en) 2017-09-28
JP5705985B2 (ja) 2015-04-22
EA022500B1 (ru) 2016-01-29
AP3270A (en) 2015-05-31
CA2810393A1 (en) 2012-03-08
KR101378984B1 (ko) 2014-03-27
BR112013004988A2 (pt) 2016-05-31
WO2012030106A3 (en) 2012-05-18
PE20131128A1 (es) 2013-10-18
AU2011296767B2 (en) 2015-04-23
KR20120060139A (ko) 2012-06-11
IL224954B (en) 2018-11-29
SG188329A1 (en) 2013-04-30
AU2011296767A1 (en) 2013-03-14
WO2012030106A2 (en) 2012-03-08
JP2013543484A (ja) 2013-12-05
ECSP13012471A (es) 2013-04-30
US20130165659A1 (en) 2013-06-27
MA34490B1 (fr) 2013-08-01
CN103080088B (zh) 2014-09-24
MY157423A (en) 2016-06-15
NZ607694A (en) 2015-08-28
CO6700826A2 (es) 2013-06-28
CL2013000589A1 (es) 2013-07-12
EA201390336A1 (ru) 2013-07-30
EP2611776B1 (en) 2016-09-21
PT2611776T (pt) 2016-12-20
CA2810393C (en) 2016-04-12
EP2611776A4 (en) 2014-08-20
UY33589A (es) 2011-12-01
AP2013006763A0 (en) 2013-03-31
UA107721C2 (ru) 2015-02-10
ES2607089T3 (es) 2017-03-29
SI2611776T1 (sl) 2017-03-31

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