PL2529033T3 - Sposoby do przewidywania ryzyka, diagnozowania i prognozowania zaburzeń płucnych - Google Patents

Sposoby do przewidywania ryzyka, diagnozowania i prognozowania zaburzeń płucnych

Info

Publication number
PL2529033T3
PL2529033T3 PL11737602T PL11737602T PL2529033T3 PL 2529033 T3 PL2529033 T3 PL 2529033T3 PL 11737602 T PL11737602 T PL 11737602T PL 11737602 T PL11737602 T PL 11737602T PL 2529033 T3 PL2529033 T3 PL 2529033T3
Authority
PL
Poland
Prior art keywords
prognosis
diagnosis
methods
risk prediction
pulmonary disorders
Prior art date
Application number
PL11737602T
Other languages
English (en)
Inventor
David Schwartz
Max Seibold
Original Assignee
Nat Jewish Health
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nat Jewish Health filed Critical Nat Jewish Health
Publication of PL2529033T3 publication Critical patent/PL2529033T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/118Prognosis of disease development
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/136Screening for pharmacological compounds
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/172Haplotypes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701Details
    • G01N2333/4725Mucins, e.g. human intestinal mucin
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/12Pulmonary diseases
PL11737602T 2010-01-26 2011-01-26 Sposoby do przewidywania ryzyka, diagnozowania i prognozowania zaburzeń płucnych PL2529033T3 (pl)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US29847310P 2010-01-26 2010-01-26
US29881410P 2010-01-27 2010-01-27
US32323810P 2010-04-12 2010-04-12
US32376010P 2010-04-13 2010-04-13
EP11737602.0A EP2529033B1 (en) 2010-01-26 2011-01-26 Methods for risk prediction, diagnosis, prognosis of pulmonary disorders
PCT/US2011/022621 WO2011094345A1 (en) 2010-01-26 2011-01-26 Methods and compositions for risk prediction, diagnosis, prognosis, and treatment of pulmonary disorders

Publications (1)

Publication Number Publication Date
PL2529033T3 true PL2529033T3 (pl) 2017-10-31

Family

ID=44319751

Family Applications (1)

Application Number Title Priority Date Filing Date
PL11737602T PL2529033T3 (pl) 2010-01-26 2011-01-26 Sposoby do przewidywania ryzyka, diagnozowania i prognozowania zaburzeń płucnych

Country Status (10)

Country Link
US (6) US8673565B2 (pl)
EP (1) EP2529033B1 (pl)
CA (2) CA3101636A1 (pl)
DK (1) DK2529033T3 (pl)
ES (1) ES2636671T3 (pl)
HU (1) HUE033044T2 (pl)
MX (1) MX344543B (pl)
PL (1) PL2529033T3 (pl)
SI (1) SI2529033T1 (pl)
WO (1) WO2011094345A1 (pl)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3101636A1 (en) 2010-01-26 2011-08-04 National Jewish Health Diagnosis and prognosis of idiopathic interstitial pneumonia by rs35705950 snp in muc5b gene promoter
US20140315210A1 (en) * 2011-12-21 2014-10-23 University College Dublin, National University Of Ireland, Dublin Methods relating to idiopathic pulmonary fibrosis (ipf)
WO2014121180A1 (en) * 2013-02-01 2014-08-07 The University Of Chicago Genetic variants in interstitial lung disease subjects
KR102544414B1 (ko) * 2013-02-14 2023-06-15 더 리전츠 오브 더 유니버시티 오브 콜로라도, 어 바디 코퍼레이트 간질 폐렴의 위험을 예측하는 방법
EP3626308A1 (en) 2013-03-14 2020-03-25 Veracyte, Inc. Methods for evaluating copd status
EP4219761A1 (en) * 2013-03-15 2023-08-02 Veracyte, Inc. Biomarkers for diagnosis of lung diseases and methods of use thereof
JP6141160B2 (ja) 2013-09-25 2017-06-07 ソニーセミコンダクタソリューションズ株式会社 固体撮像素子およびその動作方法、並びに電子機器およびその動作方法
CN107206043A (zh) 2014-11-05 2017-09-26 维拉赛特股份有限公司 使用机器学习和高维转录数据在经支气管活检上诊断特发性肺纤维化的系统和方法
EP3285794B1 (en) * 2015-04-22 2020-03-18 The University of Chicago Methods for treating idiopathic pulmonary fibrosis
NZ760756A (en) 2017-06-26 2024-02-23 Univ Colorado Regents Biomarkers for the diagnosis and treatment of fibrotic lung disease
WO2021142245A1 (en) * 2020-01-10 2021-07-15 Translate Bio, Inc. Compounds, pharmaceutical compositions and methods for modulating expression of muc5b in lung cells and tissues
WO2022087329A1 (en) * 2020-10-23 2022-04-28 Alnylam Pharmaceuticals, Inc. Mucin 5b (muc5b) irna compositions and methods of use thereof
WO2023105527A1 (en) * 2021-12-09 2023-06-15 Splisense Ltd. Muc5-targeted antisense oligonucleotides and related methods for modulating expression of muc5ac and muc5b

Family Cites Families (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
EP0173494A3 (en) 1984-08-27 1987-11-25 The Board Of Trustees Of The Leland Stanford Junior University Chimeric receptors by dna splicing and expression
EP0247091B1 (en) 1985-11-01 1993-09-29 Xoma Corporation Modular assembly of antibody genes, antibodies prepared thereby and use
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
US5143854A (en) 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
US5859205A (en) 1989-12-21 1999-01-12 Celltech Limited Humanised antibodies
US5637459A (en) 1990-06-11 1997-06-10 Nexstar Pharmaceuticals, Inc. Systematic evolution of ligands by exponential enrichment: chimeric selex
US5496938A (en) 1990-06-11 1996-03-05 Nexstar Pharmaceuticals, Inc. Nucleic acid ligands to HIV-RT and HIV-1 rev
US5582981A (en) 1991-08-14 1996-12-10 Gilead Sciences, Inc. Method for identifying an oligonucleotide aptamer specific for a target
US5777085A (en) 1991-12-20 1998-07-07 Protein Design Labs, Inc. Humanized antibodies reactive with GPIIB/IIIA
US6210671B1 (en) 1992-12-01 2001-04-03 Protein Design Labs, Inc. Humanized antibodies reactive with L-selectin
US5830645A (en) 1994-12-09 1998-11-03 The Regents Of The University Of California Comparative fluorescence hybridization to nucleic acid arrays
US7144699B2 (en) * 1997-03-20 2006-12-05 Affymetrix, Inc. Iterative resequencing
US6339075B1 (en) 1997-06-30 2002-01-15 The University Of British Columbia Use of dextran and other polysaccharides to improve mucus clearance
TW589189B (en) 1997-08-04 2004-06-01 Scras Kit containing at least one double-stranded RNA combined with at least one anti-viral agent for therapeutic use in the treatment of a viral disease, notably of viral hepatitis
US6506559B1 (en) 1997-12-23 2003-01-14 Carnegie Institute Of Washington Genetic inhibition by double-stranded RNA
AUPP249298A0 (en) 1998-03-20 1998-04-23 Ag-Gene Australia Limited Synthetic genes and genetic constructs comprising same I
GB9827152D0 (en) 1998-07-03 1999-02-03 Devgen Nv Characterisation of gene function using double stranded rna inhibition
KR100483494B1 (ko) 1998-12-01 2005-04-15 프로테인 디자인 랩스 인코포레이티드 감마 인터페론에 대한 인간화 항체
CA2361201A1 (en) 1999-01-28 2000-08-03 Medical College Of Georgia Research Institute, Inc. Composition and method for in vivo and in vitro attenuation of gene expression using double stranded rna
DE19956568A1 (de) 1999-01-30 2000-08-17 Roland Kreutzer Verfahren und Medikament zur Hemmung der Expression eines vorgegebenen Gens
EP1235842A4 (en) 1999-10-15 2003-04-23 Univ Massachusetts GENESIS OF THE RNA INTERFERENCE PATH AS AID OF TARGETED GENTIAN INTERFERENCE
GB9927444D0 (en) 1999-11-19 2000-01-19 Cancer Res Campaign Tech Inhibiting gene expression
US20020037538A1 (en) * 2000-05-09 2002-03-28 Trepicchio William L. Compositions, kits, and methods for identification, assessment, prevention, and therapy of psoriasis
JP2004532616A (ja) 2000-12-28 2004-10-28 ジョンソン・アンド・ジョンソン・リサーチ・ピー・ティー・ワイ・リミテッド 二本鎖rna仲介遺伝子抑制
US20030092019A1 (en) * 2001-01-09 2003-05-15 Millennium Pharmaceuticals, Inc. Methods and compositions for diagnosing and treating neuropsychiatric disorders such as schizophrenia
US20030040009A1 (en) 2001-08-14 2003-02-27 University Of Southern California Saliva-based methods for preventing and assessing the risk of diseases
US6818446B2 (en) * 2001-11-21 2004-11-16 The Regents Of The University Of California Compositions and methods for the analysis of mucin gene expression and identification of drugs having the ability to inhibit mucin gene expression
AU2002950878A0 (en) 2002-08-20 2002-09-12 Proteome Systems Intellectual Property Pty Ltd Method for diagnosing disorders
EP1403638A1 (en) 2002-09-25 2004-03-31 Mondobiotech SA Molecular methods for diagnosing interstitial lung diseases
US7300788B2 (en) * 2002-10-08 2007-11-27 Affymetrix, Inc. Method for genotyping polymorphisms in humans
US20070202109A1 (en) * 2003-09-24 2007-08-30 Oncotherapy Science, Inc. Method Of Diagnosing Breast Cancer
US20050125851A1 (en) * 2003-12-09 2005-06-09 Children's Hospital Research Foundation Methods of diagnosis and treatment of interstitial lung disease
JP4825956B2 (ja) 2004-05-19 2011-11-30 財団法人ヒューマンサイエンス振興財団 気道粘膜炎症性疾患の罹患リスクの判定
KR20080011292A (ko) 2005-05-19 2008-02-01 시너젠즈 바이오사이언스 리미티드 유전자 다형 분석을 사용하여 폐암 발생 위험을 평가하는방법
CA2666584A1 (en) 2006-10-17 2008-04-24 Synergenz Bioscience Limited Methods and compositions for assessment of pulmonary function and disorders
US20100119474A1 (en) 2007-03-06 2010-05-13 Cornell University Chronic obstructive pulmonary disease susceptibility and related compositions and methods
US20120094842A1 (en) * 2007-11-01 2012-04-19 Peter Durie Methods of assessing and treating pulmonary disease
WO2009073167A2 (en) 2007-12-03 2009-06-11 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Identification and diagnosis of pulmonary fibrosis using mucin genes, and related methods and compositions
WO2009140715A1 (en) 2008-05-21 2009-11-26 Central Northern Adelaide Health Service Diagnostic method
DE102010027032A1 (de) 2009-07-20 2011-02-17 Sigismund Laskowski Trageverpackung zur Aufnahme von Behältnissen
CA3101636A1 (en) 2010-01-26 2011-08-04 National Jewish Health Diagnosis and prognosis of idiopathic interstitial pneumonia by rs35705950 snp in muc5b gene promoter

Also Published As

Publication number Publication date
WO2011094345A1 (en) 2011-08-04
US11649503B2 (en) 2023-05-16
CA3101636A1 (en) 2011-08-04
CA2787994A1 (en) 2011-08-04
EP2529033B1 (en) 2017-05-24
EP2529033A1 (en) 2012-12-05
US20110217315A1 (en) 2011-09-08
MX344543B (es) 2016-12-19
US20140220570A1 (en) 2014-08-07
US20210198738A1 (en) 2021-07-01
US8673565B2 (en) 2014-03-18
US20170183730A1 (en) 2017-06-29
US20230313307A1 (en) 2023-10-05
US10858707B2 (en) 2020-12-08
MX2012008730A (es) 2012-12-17
SI2529033T1 (sl) 2017-08-31
DK2529033T3 (en) 2017-08-07
US20190040467A1 (en) 2019-02-07
CA2787994C (en) 2021-01-12
ES2636671T3 (es) 2017-10-06
HUE033044T2 (hu) 2017-11-28
EP2529033A4 (en) 2013-07-17

Similar Documents

Publication Publication Date Title
SI2529033T1 (sl) Postopki za napovedovanje tveganja, diagnozo, prognozo pljučnih obolenj
HK1200933A1 (zh) 改善炎性腸病診斷的方法
IL222232A0 (en) Circulating biomarkers for disease
EP2606353A4 (en) CIRCULATING BIOMARKERS FOR DISEASE
PL2748605T3 (pl) Sposoby i kompozycje do diagnozowania i prognozowania uszkodzenia nerek i niewydolności nerek
EP2788759A4 (en) METHODS AND COMPOSITIONS FOR DIAGNOSING AND PROGNOSING KIDNEY INJURY AND RENAL FAILURE
EP2556479A4 (en) METHOD FOR MONETIZING ANONYMIZED CONTEXTS
RS55406B1 (sr) Novi ko-kristali agomelatina
EP2723866A4 (en) METHOD FOR THE PROGNOSIS AND / OR DIAGNOSIS OF NEURODEEGENERATIVE DISEASES, METHOD FOR IDENTIFYING COMPOUND CANDIDATES AND COMPOUNDS FOR THE TREATMENT OF NEURODEGENATIVE DISEASES
EP2888370A4 (en) DIAGNOSIS, FORECASTING AND TREATMENT PROCEDURES
EP2696756A4 (en) METHODS FOR THE DIAGNOSIS, PROGNOSIS, MONITORING AND TREATMENT OF HEPATOCELULAR CARCINOMA
IL231982A0 (en) A method for the diagnosis of Niemann-Pick disease
EP2729803A4 (en) METHODS AND COMPOSITIONS FOR DIAGNOSING AND PROGNOSING RENAL INJURY AND RENAL FAILURE
EP2661626A4 (en) METHOD AND COMPOSITIONS FOR DIAGNOSIS AND FORECASTING kidney injury and kidney insufficiency
EP2783213A4 (en) METHODS AND COMPOSITIONS FOR THE DIAGNOSIS AND PROGNOSIS OF RENAL INJURY AND RENAL FAILURE
GB201011420D0 (en) Method for diagnosis
EP2539714A4 (en) BIOMARKERS OF MUSCULOSKELETAL DISEASE
HK1200877A1 (en) Method for monitoring, diagnosis and/or prognosis of hypoxia related disorders using nfat5 nfat5 /
EP2704800A4 (en) PROCESS FOR PREDICTING THE DEVELOPMENT OF COMPLEMENT-MEDIATED DISEASES
EP2598875A4 (en) PROCESS FOR SCOLIOSIS DIAGNOSIS ON BIOMEDICAL BASIS
EP2653872A4 (en) BIOMARKERS FOR AMYLOID-BETA-MEDIATED NEUROLOGICAL ILLNESSES
AP2013006853A0 (en) Biomarker for vavular heart disease
IL228581A0 (en) Compounds and methods for treatment, diagnosis and detection of disease
ZA201401630B (en) Method for assessing perspiration reduction
GB201001073D0 (en) Methods & Devices for diagnosing cardiac disorders