PL250073B1 - Peptydowa pochodna fosfonowego analogu argininy Cbz-Ile-Tyr-Arg<sup>P</sup>(OPh)<sub>2</sub> do zastosowania jako środek przeciwbakteryjny - Google Patents

Peptydowa pochodna fosfonowego analogu argininy Cbz-Ile-Tyr-Arg<sup>P</sup>(OPh)<sub>2</sub> do zastosowania jako środek przeciwbakteryjny

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Publication number
PL250073B1
PL250073B1 PL445141A PL44514123A PL250073B1 PL 250073 B1 PL250073 B1 PL 250073B1 PL 445141 A PL445141 A PL 445141A PL 44514123 A PL44514123 A PL 44514123A PL 250073 B1 PL250073 B1 PL 250073B1
Authority
PL
Poland
Prior art keywords
argp
oph
cbz
phosphonic
ile
Prior art date
Application number
PL445141A
Other languages
English (en)
Other versions
PL445141A1 (pl
Inventor
Ewa Burchacka
Original Assignee
Politechnika Wrocławska
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Politechnika Wrocławska filed Critical Politechnika Wrocławska
Priority to PL445141A priority Critical patent/PL250073B1/pl
Publication of PL445141A1 publication Critical patent/PL445141A1/pl
Publication of PL250073B1 publication Critical patent/PL250073B1/pl

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/06—Tripeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

Przedmiotem wynalazku jest zastosowanie peptydowej pochodnej fosfonowego analogu argininy Cbz-Ile-Tyr-ArgP(OPh)2 o wzorze 1 jako środka przeciwbakteryjnego do eliminowania bakterii wybranych z grupy: Finegoldia magna, Escherichia coli, Staphylococcus aureus, Serratia marcescens.
PL445141A 2023-06-06 2023-06-06 Peptydowa pochodna fosfonowego analogu argininy Cbz-Ile-Tyr-Arg<sup>P</sup>(OPh)<sub>2</sub> do zastosowania jako środek przeciwbakteryjny PL250073B1 (pl)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PL445141A PL250073B1 (pl) 2023-06-06 2023-06-06 Peptydowa pochodna fosfonowego analogu argininy Cbz-Ile-Tyr-Arg<sup>P</sup>(OPh)<sub>2</sub> do zastosowania jako środek przeciwbakteryjny

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL445141A PL250073B1 (pl) 2023-06-06 2023-06-06 Peptydowa pochodna fosfonowego analogu argininy Cbz-Ile-Tyr-Arg<sup>P</sup>(OPh)<sub>2</sub> do zastosowania jako środek przeciwbakteryjny

Publications (2)

Publication Number Publication Date
PL445141A1 PL445141A1 (pl) 2024-12-09
PL250073B1 true PL250073B1 (pl) 2026-08-10

Family

ID=93799880

Family Applications (1)

Application Number Title Priority Date Filing Date
PL445141A PL250073B1 (pl) 2023-06-06 2023-06-06 Peptydowa pochodna fosfonowego analogu argininy Cbz-Ile-Tyr-Arg<sup>P</sup>(OPh)<sub>2</sub> do zastosowania jako środek przeciwbakteryjny

Country Status (1)

Country Link
PL (1) PL250073B1 (pl)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL212735B1 (pl) * 2006-02-28 2012-11-30 Politechnika Wroclawska Sposób wytwarzania fosfonowych analogów pseudopeptydów i ich zastosowanie jako preparatów o aktywności przeciwbakteryjnej

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL212735B1 (pl) * 2006-02-28 2012-11-30 Politechnika Wroclawska Sposób wytwarzania fosfonowych analogów pseudopeptydów i ich zastosowanie jako preparatów o aktywności przeciwbakteryjnej

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
BURCHACKA E. ET AL.,: "Biochimie, Volume 103, 08.2014., pp 137-143.", SUBSTRATE PROFILING OF FINEGOLDIA MAGNA SUFA PROTEASE, INHIBITOR SCREENING AND APPLICATION TO PREVENT HUMAN FIBRINOGEN DEGRADATION AND BACTERIA GROWTH IN VITRO *
SKOREŃSKI M, MILEWSKA A, PYRĆ K, SIEŃCZYK M, OLEKSYSZYN J.: "J Enzyme Inhib Med Chem. 2019 Dec;34(1):8-14.", PHOSPHONATE INHIBITORS OF WEST NILE VIRUS NS2B/NS3 PROTEASE *

Also Published As

Publication number Publication date
PL445141A1 (pl) 2024-12-09