PL2417139T3 - Wytwarzanie nasyconych związków ketonowo-morfinanowych za pomocą katalitycznej izomeryzacji - Google Patents

Wytwarzanie nasyconych związków ketonowo-morfinanowych za pomocą katalitycznej izomeryzacji

Info

Publication number
PL2417139T3
PL2417139T3 PL10714136.8T PL10714136T PL2417139T3 PL 2417139 T3 PL2417139 T3 PL 2417139T3 PL 10714136 T PL10714136 T PL 10714136T PL 2417139 T3 PL2417139 T3 PL 2417139T3
Authority
PL
Poland
Prior art keywords
preparation
catalytic isomerization
saturated ketone
morphinan compounds
ketone morphinan
Prior art date
Application number
PL10714136.8T
Other languages
English (en)
Inventor
Peter X. Wang
Tao Jiang
David W. Berberich
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of PL2417139T3 publication Critical patent/PL2417139T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D489/00Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/02Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with oxygen atoms attached in positions 3 and 6, e.g. morphine, morphinone
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D489/00Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/02Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with oxygen atoms attached in positions 3 and 6, e.g. morphine, morphinone
    • C07D489/04Salts; Organic complexes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
PL10714136.8T 2009-04-09 2010-04-09 Wytwarzanie nasyconych związków ketonowo-morfinanowych za pomocą katalitycznej izomeryzacji PL2417139T3 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US16787609P 2009-04-09 2009-04-09

Publications (1)

Publication Number Publication Date
PL2417139T3 true PL2417139T3 (pl) 2016-09-30

Family

ID=42229123

Family Applications (1)

Application Number Title Priority Date Filing Date
PL10714136.8T PL2417139T3 (pl) 2009-04-09 2010-04-09 Wytwarzanie nasyconych związków ketonowo-morfinanowych za pomocą katalitycznej izomeryzacji

Country Status (5)

Country Link
US (1) US8293907B2 (pl)
EP (1) EP2417139B1 (pl)
ES (1) ES2571232T3 (pl)
PL (1) PL2417139T3 (pl)
WO (1) WO2010118271A1 (pl)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8383815B2 (en) * 2009-09-21 2013-02-26 Mallinckrodt Llc Heterogeneous ruthenium metal catalyst for the production of hydrocodone, hydromorphone or a derivative thereof
GB201313211D0 (en) 2013-07-24 2013-09-04 Cambrex Karlskoga Ab New process
US10081636B2 (en) 2016-07-08 2018-09-25 Cody Laboratories, Inc. Method for catalytic preparation of hydromorphone, hydrocodone, and other opiates
US20240043447A1 (en) 2020-11-13 2024-02-08 Ferrer Internacional, S.A. Synthesis of hydromorphone base

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2577947A (en) 1951-12-11 Manufacture of dihydrocodeinone
US2544291A (en) 1949-04-05 1951-03-06 New York Quinine And Chemical Alkaloid manufacture
US2654756A (en) 1949-10-20 1953-10-06 Mallinckrodt Chemical Works Process of preparing codeinone, dihydrocodeinone, and dihydromorphinone
US2628962A (en) 1949-10-20 1953-02-17 Mallinckrodt Chemical Works Method for preparing dihydrocodeinone, dihydromorphinone, and codeinone
US2715626A (en) 1950-07-05 1955-08-16 Merck & Co Inc Process of preparing dihydrocodeinone
US2649454A (en) 1951-08-20 1953-08-18 Univ California Method for preparing dihydromorphinone, dihydrocodeinone, and dihydropseudocodeinone
GB9213524D0 (en) 1992-06-25 1992-08-12 Macfarlan Smith Ltd Biocatalysis in the synthesis of analgesic and antitussive compounds
GB9616253D0 (en) 1996-08-01 1996-09-11 Johnson Matthey Plc Preparation of narcotic analgesics
EP2003134B1 (en) 1999-11-09 2011-03-02 Abbott Laboratories Hydromorphinone compositions
US7323565B2 (en) 2002-11-11 2008-01-29 Mallinckrodt Inc. Method for the catalytic production of hydrocodone and hydromorphone
US7399858B2 (en) * 2002-11-11 2008-07-15 Mallinckrodt Inc. Method for the catalytic production of hydrocodone, hydromorphone, and derivatives thereof
US7321038B2 (en) 2002-11-11 2008-01-22 Mallinckrodt Inc. Method for the catalytic production of hydrocodone and hydromorphone
US7201453B2 (en) 2004-01-30 2007-04-10 Stone Construction Equipment, Inc. Mortar buggy with stake bed assembly
SK286047B6 (sk) * 2004-04-13 2008-01-07 Zentiva, A. S. Spôsob prípravy derivátov 4,5alfa-epoxy-6-oxomorfínanu
US7399859B1 (en) 2007-02-06 2008-07-15 Cody Laboratories Inc. Method for catalytic preparation of hydromorphone and hydrocodone

Also Published As

Publication number Publication date
US8293907B2 (en) 2012-10-23
US20100261904A1 (en) 2010-10-14
ES2571232T3 (es) 2016-05-24
EP2417139A1 (en) 2012-02-15
EP2417139B1 (en) 2016-03-23
WO2010118271A1 (en) 2010-10-14

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