PL2225271T3 - New non-selective somatostatin analogues - Google Patents

New non-selective somatostatin analogues

Info

Publication number
PL2225271T3
PL2225271T3 PL08856519T PL08856519T PL2225271T3 PL 2225271 T3 PL2225271 T3 PL 2225271T3 PL 08856519 T PL08856519 T PL 08856519T PL 08856519 T PL08856519 T PL 08856519T PL 2225271 T3 PL2225271 T3 PL 2225271T3
Authority
PL
Poland
Prior art keywords
new non
somatostatin analogues
selective somatostatin
selective
analogues
Prior art date
Application number
PL08856519T
Other languages
Polish (pl)
Inventor
Andrea Vitali
Massimo Pinori
Paolo Mascagni
Original Assignee
Italfarmaco Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from ITMI20072266 external-priority patent/ITMI20072266A1/en
Priority claimed from EP07425778A external-priority patent/EP2067786A1/en
Application filed by Italfarmaco Spa filed Critical Italfarmaco Spa
Publication of PL2225271T3 publication Critical patent/PL2225271T3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • C07K14/6555—Somatostatins at least 1 amino acid in D-form

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Endocrinology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pain & Pain Management (AREA)
  • Vascular Medicine (AREA)
  • Transplantation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
PL08856519T 2007-12-03 2008-11-24 New non-selective somatostatin analogues PL2225271T3 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
ITMI20072266 ITMI20072266A1 (en) 2007-12-03 2007-12-03 NEW NON-SELECTIVE SOMATOSTATINE ANALOGUES
EP07425778A EP2067786A1 (en) 2007-12-07 2007-12-07 Novel non selective analogs of somatostatin
PCT/EP2008/066081 WO2009071460A2 (en) 2007-12-03 2008-11-24 New non-selective somatostatin analogues
EP08856519.7A EP2225271B1 (en) 2007-12-03 2008-11-24 New non-selective somatostatin analogues

Publications (1)

Publication Number Publication Date
PL2225271T3 true PL2225271T3 (en) 2013-12-31

Family

ID=40667736

Family Applications (1)

Application Number Title Priority Date Filing Date
PL08856519T PL2225271T3 (en) 2007-12-03 2008-11-24 New non-selective somatostatin analogues

Country Status (15)

Country Link
US (1) US8937152B2 (en)
EP (1) EP2225271B1 (en)
JP (1) JP5331817B2 (en)
KR (1) KR101500528B1 (en)
CN (1) CN101883785B (en)
BR (1) BRPI0818978B8 (en)
CA (1) CA2702940C (en)
CY (1) CY1114490T1 (en)
DK (1) DK2225271T3 (en)
ES (1) ES2431573T3 (en)
HR (1) HRP20130948T1 (en)
PL (1) PL2225271T3 (en)
PT (1) PT2225271E (en)
SI (1) SI2225271T1 (en)
WO (1) WO2009071460A2 (en)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2682174C (en) 2007-03-28 2021-04-06 President And Fellows Of Harvard College Stitched polypeptides
PL2225271T3 (en) * 2007-12-03 2013-12-31 Italfarmaco Spa New non-selective somatostatin analogues
KR20130099938A (en) 2010-08-13 2013-09-06 에일러론 테라퓨틱스 인코포레이티드 Peptidomimetic macrocycles
EP2752425A4 (en) * 2011-09-04 2015-04-22 Glytech Inc GLYCOSYLATED POLYPEPTIDE AND DRUG COMPOSITION CONTAINING THE POLYPEPTIDE
CN104039342A (en) 2011-10-18 2014-09-10 爱勒让治疗公司 peptidomimetic macrocycle
HK1205454A1 (en) 2012-02-15 2015-12-18 Aileron Therapeutics, Inc. Triazole-crosslinked and thioether-crosslinked peptidomimetic macrocycles
NZ627528A (en) 2012-02-15 2016-05-27 Aileron Therapeutics Inc Peptidomimetic macrocycles
SG11201503052RA (en) 2012-11-01 2015-05-28 Aileron Therapeutics Inc Disubstituted amino acids and methods of preparation and use thereof
DK3007704T3 (en) * 2013-06-13 2021-03-29 Antisense Therapeutics Ltd Combination therapy for acromegaly
CN103467575B (en) * 2013-08-22 2016-03-02 深圳翰宇药业股份有限公司 A kind of preparation method of Pa Xirui peptide
CN103641894B (en) * 2013-12-06 2015-10-28 深圳翰宇药业股份有限公司 A kind of preparation method treating the polypeptide drugs of hypercortisolism
MX2017003797A (en) 2014-09-24 2017-06-15 Aileron Therapeutics Inc Peptidomimetic macrocycles and uses thereof.
CN104447962B (en) * 2014-12-29 2018-07-17 成都圣诺生物科技股份有限公司 A method of synthesis parritide
WO2016154058A1 (en) 2015-03-20 2016-09-29 Aileron Therapeutics, Inc. Peptidomimetic macrocycles and uses thereof
JP7358484B2 (en) * 2018-09-25 2023-10-10 アドヴァンスド・アクセラレーター・アプリケーションズ・（イタリー）・エッセエッレエッレ combination therapy
GB201816637D0 (en) * 2018-10-12 2018-11-28 Heptares Therapeutics Ltd Selective somatostatin receptor agonists
US20240165282A1 (en) * 2021-03-04 2024-05-23 Starget Pharma Ltd. Conformational constrained somatostatin receptor 3 peptide ligands and their conjugates and uses thereof
IT202100032615A1 (en) 2021-12-24 2023-06-24 Italfarmaco Spa Use of a somatostatin agonist in the treatment of SSTR3-expressing tumors
CN119708199A (en) * 2023-09-27 2025-03-28 钱杭江医药科技(嘉兴)有限公司 Somatostatin peptide analogue, chelate and application thereof

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY147327A (en) * 1995-06-29 2012-11-30 Novartis Ag Somatostatin peptides
GB0018891D0 (en) 2000-08-01 2000-09-20 Novartis Ag Organic compounds
US6365380B2 (en) * 2000-02-23 2002-04-02 Pcbu Services, Inc. Method for stereoselectively inverting a chiral center of a chemical compound using an enzyme and a metal catalyst
WO2003077878A1 (en) * 2002-03-12 2003-09-25 The Procter & Gamble Company Cosmetic composition comprising double coated pigment
GB0206415D0 (en) 2002-03-19 2002-05-01 Glaxo Group Ltd Deracemisation of amines
GB0300095D0 (en) * 2003-01-03 2003-02-05 Novartis Ag Organic compounds
PE20050285A1 (en) * 2003-06-24 2005-06-09 Novartis Ag PHARMACEUTICAL COMPOSITION INCLUDING CYCLIC ANALOGS OF SOMATOSTATIN
US20060270730A1 (en) * 2003-08-07 2006-11-30 Andreas Katopodis Histone deacetylase inhibitors as immunosuppressants
GB0318682D0 (en) 2003-08-08 2003-09-10 Novartis Ag Organic compounds
EP1522311A1 (en) * 2003-10-10 2005-04-13 Institut National De La Sante Et De La Recherche Medicale (Inserm) Use of somatostatin or analogs thereof for the preparation of a medicament for the regulation of ovarian follicles reserve by non menopausaled women
CN1905895A (en) * 2003-11-25 2007-01-31 诺瓦提斯公司 Biomarkers for the efficacy of somatostatin analogue treatment
ITFI20040057A1 (en) * 2004-03-10 2004-06-10 Mauro Giuntini ANALOGS OF THE SOMATOSTATINA
GB0428151D0 (en) 2004-12-22 2005-01-26 Novartis Ag Organic compounds
US7824663B2 (en) * 2005-03-10 2010-11-02 Kokyu Alcohol Kogyo Co., Ltd. Lip gloss composition
ATE549011T1 (en) * 2005-11-10 2012-03-15 Chemi Spa SUSTAINED RELEASE FORMULATIONS CONTAINING SOMATOSTATIN ANALOGUE GROWTH HORMONE INHIBITORS
PL2225271T3 (en) * 2007-12-03 2013-12-31 Italfarmaco Spa New non-selective somatostatin analogues

Also Published As

Publication number Publication date
CY1114490T1 (en) 2016-10-05
HRP20130948T1 (en) 2013-11-08
CN101883785B (en) 2014-01-15
JP2011505345A (en) 2011-02-24
EP2225271B1 (en) 2013-07-31
KR101500528B1 (en) 2015-03-09
US20100323964A1 (en) 2010-12-23
US8937152B2 (en) 2015-01-20
BRPI0818978B1 (en) 2019-09-10
SI2225271T1 (en) 2013-10-30
CA2702940C (en) 2016-09-13
EP2225271A2 (en) 2010-09-08
CA2702940A1 (en) 2009-06-11
CN101883785A (en) 2010-11-10
KR20100103464A (en) 2010-09-27
WO2009071460A2 (en) 2009-06-11
JP5331817B2 (en) 2013-10-30
PT2225271E (en) 2013-09-27
BRPI0818978B8 (en) 2021-05-25
ES2431573T3 (en) 2013-11-27
BRPI0818978A2 (en) 2016-05-03
WO2009071460A3 (en) 2009-12-17
DK2225271T3 (en) 2013-10-07

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