ZA201104593B - Glucagon analogues - Google Patents
Glucagon analoguesInfo
- Publication number
- ZA201104593B ZA201104593B ZA2011/04593A ZA201104593A ZA201104593B ZA 201104593 B ZA201104593 B ZA 201104593B ZA 2011/04593 A ZA2011/04593 A ZA 2011/04593A ZA 201104593 A ZA201104593 A ZA 201104593A ZA 201104593 B ZA201104593 B ZA 201104593B
- Authority
- ZA
- South Africa
- Prior art keywords
- glucagon analogues
- glucagon
- analogues
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/605—Glucagons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/GB2008/004157 WO2010070255A1 (en) | 2008-12-15 | 2008-12-15 | Glucagon analogues |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA201104593B true ZA201104593B (en) | 2015-01-28 |
Family
ID=40418466
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA2011/04593A ZA201104593B (en) | 2008-12-15 | 2011-06-22 | Glucagon analogues |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US8680049B2 (en) |
| EP (1) | EP2370462B1 (en) |
| JP (1) | JP5635532B2 (en) |
| KR (1) | KR101593406B1 (en) |
| CN (1) | CN102292348B (en) |
| AU (1) | AU2008365559B2 (en) |
| BR (1) | BRPI0823377A2 (en) |
| CA (1) | CA2747197A1 (en) |
| DK (1) | DK2370462T3 (en) |
| EA (1) | EA020596B1 (en) |
| ES (1) | ES2502218T3 (en) |
| IL (1) | IL213478A0 (en) |
| MX (1) | MX2011006315A (en) |
| NZ (1) | NZ593813A (en) |
| PL (1) | PL2370462T3 (en) |
| WO (1) | WO2010070255A1 (en) |
| ZA (1) | ZA201104593B (en) |
Families Citing this family (69)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0823376A2 (en) | 2008-12-15 | 2015-06-16 | Zealand Pharma As | Glucagon analogs |
| AU2008365555B2 (en) | 2008-12-15 | 2016-01-14 | Zealand Pharma A/S | Glucagon analogues |
| MX2011006320A (en) | 2008-12-15 | 2011-09-22 | Zealand Pharma As | Glucagon analogues. |
| ME02220B (en) | 2009-07-13 | 2016-02-20 | Zealand Pharma As | Acylated glucagon analogues |
| TWI523659B (en) | 2010-04-27 | 2016-03-01 | 西蘭製藥公司 | Peptide conjugates |
| UY33462A (en) * | 2010-06-23 | 2012-01-31 | Zealand Pharma As | GLUCAGON ANALOGS |
| SG186764A1 (en) | 2010-06-24 | 2013-02-28 | Zealand Pharma As | Glucagon analogues |
| AR085086A1 (en) * | 2011-01-20 | 2013-09-11 | Zealand Pharma As | USE OF ACILATED GLUCAGON ANALOGS |
| WO2013004983A1 (en) | 2011-07-04 | 2013-01-10 | Imperial Innovations Limited | Novel compounds and their effects on feeding behaviour |
| JP6352806B2 (en) | 2011-09-23 | 2018-07-04 | ノヴォ ノルディスク アー／エス | New glucagon analogues |
| MX2014005351A (en) | 2011-11-03 | 2014-05-28 | Zealand Pharma As | Glp-1 receptor agonist peptide gastrin conjugates. |
| CN104144696A (en) * | 2011-12-23 | 2014-11-12 | 西兰制药公司 | Glucagon analogues |
| BR112014027348B1 (en) | 2012-05-03 | 2022-12-20 | Zealand Pharma A/S | GIP-GLP-1 DOUBLE AGONIST COMPOUNDS AND METHODS |
| WO2013170636A1 (en) | 2012-05-18 | 2013-11-21 | 爱德迪安（北京）生物技术有限公司 | Protein and protein conjugate for diabetes treatment, and applications thereof |
| EA201590011A1 (en) | 2012-06-14 | 2015-05-29 | Санофи | PEPTIDE ANALOGUES EXENDIN-4 |
| US10442847B2 (en) | 2012-07-23 | 2019-10-15 | Zealand Pharma A/S | Glucagon analogues |
| KR101968344B1 (en) * | 2012-07-25 | 2019-04-12 | 한미약품 주식회사 | A composition for treating hyperlipidemia comprising oxyntomodulin analog |
| TWI608013B (en) | 2012-09-17 | 2017-12-11 | 西蘭製藥公司 | Glucagon analogues |
| AR092873A1 (en) | 2012-09-26 | 2015-05-06 | Cadila Healthcare Ltd | PEPTIDES AS TRIPLE AGONISTS OF GIP, GLP-1 AND GLUGAGON RECEPTORS |
| UA116217C2 (en) | 2012-10-09 | 2018-02-26 | Санофі | Exendin-4 derivatives as dual glp1/glucagon agonists |
| EP2934569A1 (en) | 2012-12-21 | 2015-10-28 | Sanofi | Exendin-4 derivatives |
| CN105189465B (en) | 2013-03-21 | 2019-02-26 | 赛诺菲-安万特德国有限公司 | Synthesize the peptide prod containing hydantoins |
| US10450343B2 (en) | 2013-03-21 | 2019-10-22 | Sanofi-Aventis Deutschland Gmbh | Synthesis of cyclic imide containing peptide products |
| WO2014161835A1 (en) | 2013-04-03 | 2014-10-09 | Sanofi | Modified blood glucose regulating proteins with altered pharmacological activity profile and preparation thereof |
| BR112015025464A2 (en) | 2013-04-18 | 2017-10-10 | Novo Nordisk As | stable, prolonged glp-1 / glucagon receptor coagonists for medical use |
| US9988429B2 (en) | 2013-10-17 | 2018-06-05 | Zealand Pharma A/S | Glucagon analogues |
| BR112016008115B1 (en) | 2013-10-17 | 2024-03-12 | Boehringer Ingelheim International Gmbh | ACYLATED GLUCAGON ANALOGS |
| BR112016009889B1 (en) | 2013-11-06 | 2023-11-28 | Zealand Pharma A/S | gip analogue, pharmaceutical composition comprising a gip analogue, or a pharmaceutically acceptable salt thereof, and its use |
| BR112016009995B1 (en) | 2013-11-06 | 2023-04-18 | Zealand Pharma A/S | TRIPLE AGONIST COMPOUNDS GLUCAGON-GLP-1-GIP |
| CN105934257B (en) | 2013-12-06 | 2020-10-09 | 韩捷 | Bioreversible introducing group for nitrogen and hydroxyl-containing drugs |
| TW201609799A (en) | 2013-12-13 | 2016-03-16 | 賽諾菲公司 | Dual GLP-1/GIP receptor agonists |
| EP3080152A1 (en) | 2013-12-13 | 2016-10-19 | Sanofi | Non-acylated exendin-4 peptide analogues |
| TW201609800A (en) | 2013-12-13 | 2016-03-16 | 賽諾菲公司 | EXENDIN-4 peptide analogues as dual GLP-1/glucagon receptor agonists |
| TW201609795A (en) | 2013-12-13 | 2016-03-16 | 賽諾菲公司 | EXENDIN-4 peptide analogues as dual GLP-1/GIP receptor agonists |
| WO2015086733A1 (en) | 2013-12-13 | 2015-06-18 | Sanofi | Dual glp-1/glucagon receptor agonists |
| TW201625670A (en) | 2014-04-07 | 2016-07-16 | 賽諾菲公司 | Dual GLP-1/glucagon receptor agonists derived from EXENDIN-4 |
| TW201625669A (en) | 2014-04-07 | 2016-07-16 | 賽諾菲公司 | Peptidic dual GLP-1/glucagon receptor agonists derived from Exendin-4 |
| TW201625668A (en) | 2014-04-07 | 2016-07-16 | 賽諾菲公司 | Exendin-4 derivatives as peptidic dual GLP-1/glucagon receptor agonists |
| US10570184B2 (en) | 2014-06-04 | 2020-02-25 | Novo Nordisk A/S | GLP-1/glucagon receptor co-agonists for medical use |
| US9932381B2 (en) | 2014-06-18 | 2018-04-03 | Sanofi | Exendin-4 derivatives as selective glucagon receptor agonists |
| JP6018129B2 (en) * | 2014-07-04 | 2016-11-02 | ジーランド ファーマ アクティーゼルスカブ | Glucagon analog |
| BR112017008659A2 (en) | 2014-10-29 | 2018-01-30 | Zealand Pharma As | ? gip agonist methods and compounds? |
| DK3258919T4 (en) | 2015-02-17 | 2022-11-21 | Lilly Co Eli | Nasal powder formulation for the treatment of hypoglycemia |
| CN107567459B (en) | 2015-03-18 | 2021-09-24 | 西兰制药公司 | Amylin analogs |
| WO2016168388A2 (en) | 2015-04-14 | 2016-10-20 | Palatin Technologies, Inc. | Therapies for obesity, diabetes and related indications |
| US10336802B2 (en) | 2015-04-16 | 2019-07-02 | Zealand Pharma A/S | Acylated glucagon analogue |
| AR105319A1 (en) | 2015-06-05 | 2017-09-27 | Sanofi Sa | PROPHARMS THAT INCLUDE A DUAL AGONIST GLU-1 / GLUCAGON CONJUGATE HIALURONIC ACID CONNECTOR |
| WO2016198628A1 (en) | 2015-06-12 | 2016-12-15 | Sanofi | Non-acylated exendin-4 derivatives as dual glp-1/glucagon receptor agonists |
| WO2016198624A1 (en) | 2015-06-12 | 2016-12-15 | Sanofi | Exendin-4 derivatives as trigonal glp-1/glucagon/gip receptor agonists |
| TW201706291A (en) | 2015-07-10 | 2017-02-16 | 賽諾菲公司 | New EXENDIN-4 derivatives as selective peptidic dual GLP-1/glucagon receptor agonists |
| CN105968186B (en) * | 2016-06-02 | 2020-10-30 | 中国药科大学 | Glucagon (Glu) analogue with long-acting effect and application thereof |
| MA45843B1 (en) | 2016-08-05 | 2021-06-30 | Boehringer Ingelheim Int | Oxadiazolopyridine derivatives used as ghrelin o-acyl transferase inhibitors (goat) |
| TWI784968B (en) | 2016-09-09 | 2022-12-01 | 丹麥商西蘭製藥公司 | Amylin analogues |
| AR110299A1 (en) | 2016-12-02 | 2019-03-13 | Sanofi Sa | CONJUGATES UNDERSTANDING A DUAL GLP-1 / GLUCAGON AGONIST, A CONNECTOR AND Hyaluronic Acid |
| KR102502040B1 (en) | 2016-12-09 | 2023-02-24 | 질랜드 파마 에이/에스 | Acylated GLP-1/GLP-2 dual agonists |
| CA3073011C (en) * | 2017-08-16 | 2023-06-13 | Dong-A St Co., Ltd. | Acylated oxyntomodulin peptide analog |
| EP3517543B1 (en) * | 2018-01-30 | 2020-11-04 | Bachem AG | Manufacture of glucagon peptides |
| CN111683951B (en) | 2018-02-02 | 2023-10-13 | 勃林格殷格翰国际有限公司 | Triazolopyrimidine derivatives useful as ghrelin O-acyltransferase (GOAT) inhibitors |
| JP7015396B2 (en) | 2018-02-02 | 2022-02-15 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Benzyl-, (pyridin-3-yl) methyl-or (pyridin-4-yl) methyl-substituted oxadiazolopyridine derivatives as ghrelin O-acyltransferase (GOAT) inhibitors |
| JP7225253B2 (en) | 2018-02-02 | 2023-02-20 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Pyrazole- and indazole-substituted oxadiazolopyridine derivatives for use as ghrelin O-acyltransferase (GOAT) inhibitors |
| CA3087827A1 (en) | 2018-02-02 | 2019-08-08 | Boehringer Ingelheim International Gmbh | Heterocyclyl-substituted oxadiazolopyridine derivatives for use as ghrelin o-acyl transferase (goat) inhibitors |
| EP3864032B1 (en) | 2018-10-09 | 2022-11-30 | Fresenius Kabi iPSUM S.r.l. | Process for the manufacture of glp-1 analogues |
| WO2020125744A1 (en) | 2018-12-21 | 2020-06-25 | 江苏恒瑞医药股份有限公司 | Bispecific protein |
| TWI771669B (en) | 2019-04-26 | 2022-07-21 | 美商美國禮來大藥廠 | Method for preparing stable peptide formulations |
| US20220324936A1 (en) * | 2019-06-18 | 2022-10-13 | Fresenius Kabi Ipsum S.R.L. | Process for the manufacture of glucagon |
| EP3753946A1 (en) | 2019-06-18 | 2020-12-23 | Fresenius Kabi iPSUM S.r.l. | Improved process for the preparation of high purity glucagon |
| CA3156452A1 (en) | 2019-11-11 | 2021-05-20 | Boehringer Ingelheim International Gmbh | Npy2 receptor agonists |
| AU2021264869A1 (en) * | 2020-04-29 | 2022-12-01 | Onegene Biotechnology Inc. | Novel protein conjugate, and use thereof for preventing or treating nonalcoholic steatohepatitis, obesity and diabetes |
| WO2022029231A1 (en) | 2020-08-07 | 2022-02-10 | Boehringer Ingelheim International Gmbh | Soluble npy2 receptor agonists |
Family Cites Families (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ202757A (en) | 1981-12-23 | 1985-11-08 | Novo Industri As | Peptides and medicaments |
| DE122009000079I2 (en) | 1996-08-30 | 2011-06-16 | Novo Nordisk As Novo Alle | GLP-1 DERIVATIVES |
| CA2265900C (en) | 1996-09-09 | 2007-07-31 | Zealand Pharmaceuticals A/S | Improved solid-phase peptide synthesis and agent for use in such synthesis |
| AU724326B2 (en) | 1996-09-09 | 2000-09-14 | Zealand Pharmaceuticals A/S | Peptide prodrugs containing an alpha-hydroxyacid linker |
| DE69838916T2 (en) | 1997-11-14 | 2008-12-18 | Amylin Pharmaceuticals, Inc., San Diego | NOVEL EXENDIN AGONISTS |
| IL138214A0 (en) | 1998-03-09 | 2001-10-31 | Zealand Pharmaceuticals As | Pharmacolgically active peptide conjugates having a reduced tendency towards enzymatic hydrolysis |
| NZ511931A (en) | 1998-12-07 | 2004-01-30 | Sod Conseils Rech Applic | Analogues of glucagon like peptide-1 |
| US6451987B1 (en) | 1999-03-15 | 2002-09-17 | Novo Nordisk A/S | Ion exchange chromatography of proteins and peptides |
| ES2315226T3 (en) | 1999-03-17 | 2009-04-01 | Novo Nordisk A/S | METHOD OF ACILATION OF PEPTIDES AND PROTEINS. |
| EP1076066A1 (en) | 1999-07-12 | 2001-02-14 | Zealand Pharmaceuticals A/S | Peptides for lowering blood glucose levels |
| GB0121709D0 (en) | 2001-09-07 | 2001-10-31 | Imp College Innovations Ltd | Food inhibition agent |
| AU2002346491A1 (en) | 2001-12-19 | 2003-07-09 | Eli Lilly And Company | Crystalline compositions for controlling blood glucose |
| WO2003053339A2 (en) | 2001-12-20 | 2003-07-03 | Eli Lilly And Company | Insulin molecule having protracted time action |
| GB0300571D0 (en) | 2003-01-10 | 2003-02-12 | Imp College Innovations Ltd | Modification of feeding behaviour |
| AU2004234345A1 (en) | 2003-04-29 | 2004-11-11 | Eli Lilly And Company | Insulin analogs having protracted time action |
| BRPI0612069A2 (en) | 2005-06-13 | 2009-01-20 | Imp Innovations Ltd | compounds and their effects on feeding behavior |
| WO2007024899A2 (en) | 2005-08-23 | 2007-03-01 | The General Hospital Corporation | Use of glp-1, glp-1 derivatives or glp-1 fragments for skin regeneration, stimulation of hair growth, or treatment of diabetes |
| CA2628241C (en) * | 2005-11-07 | 2016-02-02 | Indiana University Research And Technology Corporation | Glucagon analogs exhibiting physiological solubility and stability |
| US8343914B2 (en) | 2006-01-06 | 2013-01-01 | Case Western Reserve University | Fibrillation resistant proteins |
| EP2471810A1 (en) | 2006-02-22 | 2012-07-04 | Merck Sharp & Dohme Corporation | Oxyntomodulin derivatives |
| CN101622276B (en) | 2006-07-18 | 2015-04-22 | 赛诺菲-安万特 | Antagonist antibody against EphA2 for the treatment of cancer |
| EP2074140B8 (en) | 2006-10-04 | 2015-10-28 | Case Western Reserve University | Fibrillation-resistant insulin and insulin analogues |
| TWI428346B (en) | 2006-12-13 | 2014-03-01 | Imp Innovations Ltd | Novel compounds and their effects on feeding behaviour |
| KR20150116465A (en) * | 2007-02-15 | 2015-10-15 | 인디애나 유니버시티 리서치 앤드 테크놀로지 코퍼레이션 | Glucagon/glp-1 receptor co-agonists |
| EP2025684A1 (en) | 2007-08-15 | 2009-02-18 | Zealand Pharma A/S | Glucagon analogues |
| JP5385266B2 (en) | 2007-06-15 | 2014-01-08 | ジーランド ファーマ アクティーゼルスカブ | Glucagon analog |
| DK2217265T3 (en) | 2007-11-20 | 2017-07-03 | Ambrx Inc | Modified insulin polypeptides and their use |
| CA2711752A1 (en) | 2008-01-09 | 2009-07-16 | Sanofi-Aventis Deutschland Gmbh | Novel insulin derivatives having an extremely delayed time-action profile |
| DE102008003566A1 (en) | 2008-01-09 | 2009-07-16 | Sanofi-Aventis Deutschland Gmbh | New insulin analogs useful for treating diabetes |
| DE102008003568A1 (en) | 2008-01-09 | 2009-07-16 | Sanofi-Aventis Deutschland Gmbh | New insulin analogs useful for treating diabetes |
| PL2229407T3 (en) | 2008-01-09 | 2017-06-30 | Sanofi-Aventis Deutschland Gmbh | Novel insulin derivatives having an extremely delayed time-action profile |
| WO2009129250A2 (en) | 2008-04-14 | 2009-10-22 | Case Western Reserve University | Meal-time insulin analogues of enhanced stability |
| AU2009240636A1 (en) | 2008-04-22 | 2009-10-29 | Case Western Reserve University | Isoform-specific insulin analogues |
| TWI451876B (en) | 2008-06-13 | 2014-09-11 | Lilly Co Eli | Pegylated insulin lispro compounds |
| MX2010013454A (en) | 2008-06-17 | 2011-01-21 | Tion Indiana University Res And Technology Corpora | Glucagon/glp-1 receptor co-agonists. |
| CN104447980A (en) | 2008-06-17 | 2015-03-25 | 印第安纳大学研究及科技有限公司 | Glucagon analogs exhibiting enhanced solubility and stability in physiological pH buffers |
| PL219335B1 (en) | 2008-07-04 | 2015-04-30 | Inst Biotechnologii I Antybiotyków | New slow-release insulin analogues |
| KR20110061552A (en) | 2008-07-31 | 2011-06-09 | 케이스 웨스턴 리저브 유니버시티 | Halogen-stabilized insulin |
| AU2008365555B2 (en) | 2008-12-15 | 2016-01-14 | Zealand Pharma A/S | Glucagon analogues |
| BRPI0823376A2 (en) | 2008-12-15 | 2015-06-16 | Zealand Pharma As | Glucagon analogs |
| MX2011006320A (en) | 2008-12-15 | 2011-09-22 | Zealand Pharma As | Glucagon analogues. |
| CA2747490C (en) | 2008-12-19 | 2017-02-14 | Indiana University Research And Technology Corporation | Insulin analogs |
| CN102245624B (en) | 2008-12-19 | 2016-08-10 | 印第安纳大学研究及科技有限公司 | Insulin prodrug based on amide |
| CN101519446A (en) | 2009-03-31 | 2009-09-02 | 上海一就生物医药有限公司 | Method for preparing recombinant human insulin and analogs of recombinant human insulin |
| ME02220B (en) | 2009-07-13 | 2016-02-20 | Zealand Pharma As | Acylated glucagon analogues |
| JP2013517307A (en) | 2010-01-20 | 2013-05-16 | ジーランド ファーマ アクティーゼルスカブ | Heart disease treatment |
| UY33462A (en) | 2010-06-23 | 2012-01-31 | Zealand Pharma As | GLUCAGON ANALOGS |
| SG186764A1 (en) | 2010-06-24 | 2013-02-28 | Zealand Pharma As | Glucagon analogues |
| AR085086A1 (en) | 2011-01-20 | 2013-09-11 | Zealand Pharma As | USE OF ACILATED GLUCAGON ANALOGS |
-
2008
- 2008-12-15 EA EA201190048A patent/EA020596B1/en not_active IP Right Cessation
- 2008-12-15 DK DK08875673.9T patent/DK2370462T3/en active
- 2008-12-15 CN CN200880132702.8A patent/CN102292348B/en not_active Expired - Fee Related
- 2008-12-15 US US13/139,487 patent/US8680049B2/en not_active Expired - Fee Related
- 2008-12-15 WO PCT/GB2008/004157 patent/WO2010070255A1/en active Application Filing
- 2008-12-15 KR KR1020117016185A patent/KR101593406B1/en not_active IP Right Cessation
- 2008-12-15 CA CA2747197A patent/CA2747197A1/en not_active Abandoned
- 2008-12-15 JP JP2011540190A patent/JP5635532B2/en not_active Expired - Fee Related
- 2008-12-15 MX MX2011006315A patent/MX2011006315A/en active IP Right Grant
- 2008-12-15 EP EP08875673.9A patent/EP2370462B1/en not_active Not-in-force
- 2008-12-15 AU AU2008365559A patent/AU2008365559B2/en not_active Ceased
- 2008-12-15 BR BRPI0823377A patent/BRPI0823377A2/en not_active IP Right Cessation
- 2008-12-15 NZ NZ593813A patent/NZ593813A/en not_active IP Right Cessation
- 2008-12-15 PL PL08875673T patent/PL2370462T3/en unknown
- 2008-12-15 ES ES08875673.9T patent/ES2502218T3/en active Active
-
2011
- 2011-06-12 IL IL213478A patent/IL213478A0/en unknown
- 2011-06-22 ZA ZA2011/04593A patent/ZA201104593B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP2370462A1 (en) | 2011-10-05 |
| NZ593813A (en) | 2013-02-22 |
| BRPI0823377A2 (en) | 2016-09-27 |
| JP5635532B2 (en) | 2014-12-03 |
| IL213478A0 (en) | 2011-07-31 |
| CA2747197A1 (en) | 2010-06-24 |
| DK2370462T3 (en) | 2014-09-08 |
| PL2370462T3 (en) | 2015-01-30 |
| US20110286981A1 (en) | 2011-11-24 |
| KR20110126590A (en) | 2011-11-23 |
| AU2008365559A1 (en) | 2011-07-21 |
| MX2011006315A (en) | 2011-09-22 |
| EP2370462B1 (en) | 2014-07-16 |
| WO2010070255A1 (en) | 2010-06-24 |
| AU2008365559B2 (en) | 2016-02-25 |
| JP2012511902A (en) | 2012-05-31 |
| US8680049B2 (en) | 2014-03-25 |
| CN102292348B (en) | 2015-07-08 |
| EA020596B1 (en) | 2014-12-30 |
| CN102292348A (en) | 2011-12-21 |
| KR101593406B1 (en) | 2016-02-12 |
| ES2502218T3 (en) | 2014-10-03 |
| EA201190048A1 (en) | 2012-02-28 |
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