PL1931315T3 - Formulacje o przedłużonym uwalnianiu nalbufiny - Google Patents

Formulacje o przedłużonym uwalnianiu nalbufiny

Info

Publication number
PL1931315T3
PL1931315T3 PL06789964T PL06789964T PL1931315T3 PL 1931315 T3 PL1931315 T3 PL 1931315T3 PL 06789964 T PL06789964 T PL 06789964T PL 06789964 T PL06789964 T PL 06789964T PL 1931315 T3 PL1931315 T3 PL 1931315T3
Authority
PL
Poland
Prior art keywords
nalbuphine
sustained release
release formulations
formulations
sustained
Prior art date
Application number
PL06789964T
Other languages
English (en)
Inventor
Anand R Baichwal
Philip A Goliber
Anthony E Carpanzano
Thomas Sciascia
Donald Ii Diehl
Brian Vogler
Original Assignee
Endo Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Endo Pharmaceuticals Inc filed Critical Endo Pharmaceuticals Inc
Publication of PL1931315T3 publication Critical patent/PL1931315T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
PL06789964T 2005-08-24 2006-08-24 Formulacje o przedłużonym uwalnianiu nalbufiny PL1931315T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US71077205P 2005-08-24 2005-08-24
US77246606P 2006-02-10 2006-02-10
PCT/US2006/033011 WO2007025005A2 (en) 2005-08-24 2006-08-24 Sustained release formulations of nalbuphine
EP06789964.1A EP1931315B1 (en) 2005-08-24 2006-08-24 Sustained release formulations of nalbuphine

Publications (1)

Publication Number Publication Date
PL1931315T3 true PL1931315T3 (pl) 2014-09-30

Family

ID=37772363

Family Applications (2)

Application Number Title Priority Date Filing Date
PL11178912T PL2402005T3 (pl) 2005-08-24 2006-08-24 Formulacje nalbufiny o przedłużonym uwalnianiu
PL06789964T PL1931315T3 (pl) 2005-08-24 2006-08-24 Formulacje o przedłużonym uwalnianiu nalbufiny

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PL11178912T PL2402005T3 (pl) 2005-08-24 2006-08-24 Formulacje nalbufiny o przedłużonym uwalnianiu

Country Status (10)

Country Link
US (2) US8771732B2 (pl)
EP (2) EP1931315B1 (pl)
JP (1) JP2009506059A (pl)
CA (2) CA2881739C (pl)
DK (2) DK2402005T3 (pl)
ES (2) ES2441766T3 (pl)
HU (1) HUE053838T2 (pl)
PL (2) PL2402005T3 (pl)
PT (2) PT1931315E (pl)
WO (1) WO2007025005A2 (pl)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003004031A1 (en) 2001-07-06 2003-01-16 Endo Pharmaceuticals, Inc. Parenteral administration of 6-hydroxy-oxymorphone for use as an analgesic
US8487002B2 (en) * 2002-10-25 2013-07-16 Paladin Labs Inc. Controlled-release compositions
TWI319713B (en) * 2002-10-25 2010-01-21 Sustained-release tramadol formulations with 24-hour efficacy
US20060172006A1 (en) * 2003-10-10 2006-08-03 Vincent Lenaerts Sustained-release tramadol formulations with 24-hour clinical efficacy
PL1931346T3 (pl) * 2005-09-09 2013-01-31 Angelini Labopharm Llc Kompozycja trazodonu do podawania raz na dobę
EP2203166B1 (en) * 2007-10-16 2015-05-06 Paladin Labs Inc. Bilayer composition for the sustained release of acetaminophen and tramadol
AU2008338207A1 (en) 2007-12-17 2009-06-25 Labopharm (Barbados) Limited Misuse preventative, controlled release formulation
KR20110053956A (ko) * 2008-08-07 2011-05-24 아반토르 퍼포먼스 머티리얼스, 인크. 검 및 당 알콜을 포함하는 지속 방출 제제
CA2746888C (en) 2008-12-16 2015-05-12 Labopharm (Barbados) Limited Misuse preventative, controlled release formulation
FR2949061B1 (fr) * 2009-08-12 2013-04-19 Debregeas Et Associes Pharma Microgranules flottants
FR2963889B1 (fr) 2010-08-20 2013-04-12 Debregeas Et Associes Pharma Formulations a base de nalbuphine et leurs utilisations
US9918980B2 (en) 2011-04-29 2018-03-20 Rutgers, The State University Of New Jersey Method of treating dyskinesia
PL2701707T3 (pl) 2011-04-29 2021-03-08 Rutgers, The State University Of New Jersey Sposób leczenia dyskinezji
US10736889B2 (en) 2011-04-29 2020-08-11 Rutgers, The State University Of New Jersey Method of treating dyskinesia
RU2015128265A (ru) 2012-12-14 2017-01-25 Треви Терапьютикс, Инк. Способы лечения зуда
US20140179727A1 (en) 2012-12-14 2014-06-26 Trevi Therapeutics, Inc. Methods for treating pruritus
US8987289B2 (en) 2012-12-14 2015-03-24 Trevi Therapeutics, Inc. Methods for treating pruritus
US8637538B1 (en) * 2012-12-14 2014-01-28 Trevi Therapeutics, Inc. Methods for treatment of pruritis
BR112016029236A2 (pt) * 2014-06-13 2017-11-07 Trevi Therapeutics Inc métodos para tratar prurido.
JP2017100971A (ja) * 2015-11-30 2017-06-08 株式会社ファンケル 錠剤
CN105560202B (zh) * 2016-03-11 2019-05-24 广州玻思韬控释药业有限公司 一种盐酸纳布啡凝胶骨架缓释片的制备方法及应用
AU2019309913A1 (en) * 2018-07-23 2021-03-11 Trevi Therapeutics, Inc. Treatment of chronic cough, breathlessness and dyspnea
US20240131022A1 (en) * 2022-03-11 2024-04-25 John Abernethy Opioid overdose reversal mixtures

Family Cites Families (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4237140A (en) 1979-05-18 1980-12-02 E. I. Du Pont De Nemours And Company Analgesic mixture of nalbuphine and acetaminophen
US4282215A (en) 1980-06-17 1981-08-04 E. I. Du Pont De Nemours And Company Analgesic mixture of nalbuphine and acetylsalicylic acid, derivative or salt thereof
US4407805A (en) 1982-06-30 1983-10-04 E. I. Du Pont De Nemours And Company Analgesic mixture of nalbuphine and zomepirac
US4404211A (en) 1982-06-30 1983-09-13 E. I. Du Pont De Nemours And Company Analgesic mixture of nalbuphine and flurbiprofen
US4404210A (en) 1982-06-30 1983-09-13 E. I. Du Pont De Nemours And Company Analgesic mixture of nalbuphine and ibuprofen
US4404208A (en) 1982-06-30 1983-09-13 E. I. Du Pont De Nemours And Company Analgesic mixture of nalbuphine and tiflamizole
US4404209A (en) 1982-06-30 1983-09-13 E. I. Du Pont De Nemours And Company Analgesic mixture of nalbuphine and sulindac
US4407804A (en) 1982-06-30 1983-10-04 E. I. Du Pont De Nemours And Company Analgesic mixture of nalbuphine and indomethacin
US4402962A (en) 1982-06-30 1983-09-06 E. I. Du Pont De Nemours And Company Analgesic mixture of nalbuphine and 4,5-bis(4-methoxyphenyl)-2-(trifluoromethylsulfonyl)-1H-imidazole
IE58110B1 (en) 1984-10-30 1993-07-14 Elan Corp Plc Controlled release powder and process for its preparation
US4720384A (en) * 1985-05-03 1988-01-19 E. I. Du Pont De Nemours And Company Manufacture of hollow fine tubular drug delivery systems
US5013740A (en) 1990-03-22 1991-05-07 Hillel Glover Method for treating emotional numbness and coma
US5028612A (en) 1990-03-22 1991-07-02 Hillel Glover Method for treating emotional numbness
US5478577A (en) 1993-11-23 1995-12-26 Euroceltique, S.A. Method of treating pain by administering 24 hour oral opioid formulations exhibiting rapid rate of initial rise of plasma drug level
US5968551A (en) 1991-12-24 1999-10-19 Purdue Pharma L.P. Orally administrable opioid formulations having extended duration of effect
DE69427551T2 (de) 1993-03-15 2002-05-16 Nat Science Council Taipeh T A Nalbuphinester und diese enthaltende Arzneimittel mit verzögerter Wirkstoffabgabe
US5399358A (en) 1993-11-12 1995-03-21 Edward Mendell Co., Inc. Sustained release formulations for 24 hour release of metroprolol
US5750534A (en) 1994-03-16 1998-05-12 National Science Council Nalbuphine esters having long acting analgesic action and method of use
US5965161A (en) 1994-11-04 1999-10-12 Euro-Celtique, S.A. Extruded multi-particulates
US20030211157A1 (en) * 1996-05-06 2003-11-13 Simon David Lew Semi-sol delivery blend for water soluble molecules
US5948787A (en) * 1997-02-28 1999-09-07 Alza Corporation Compositions containing opiate analgesics
US6225321B1 (en) 1997-06-05 2001-05-01 Oliver Yoa-Pu Hu Long analgesic acting nalbuphine polyester derivative and method of use
US6372254B1 (en) 1998-04-02 2002-04-16 Impax Pharmaceuticals Inc. Press coated, pulsatile drug delivery system suitable for oral administration
US6602521B1 (en) 1998-09-29 2003-08-05 Impax Pharmaceuticals, Inc. Multiplex drug delivery system suitable for oral administration
US6806294B2 (en) 1998-10-15 2004-10-19 Euro-Celtique S.A. Opioid analgesic
US6248363B1 (en) 1999-11-23 2001-06-19 Lipocine, Inc. Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
CA2388560A1 (en) 1999-08-31 2001-03-08 Grunenthal Gmbh Sustained-release form of administration containing tramadol saccharinate
US6475493B1 (en) 1999-09-02 2002-11-05 Norstrum Pharmaceuticals, Inc. Controlled release pellet formulation
NZ517466A (en) 1999-09-02 2003-11-28 Nostrum Pharmaceuticals Inc Controlled release oral dosage suitable for oral administration
JP3893058B2 (ja) 1999-09-30 2007-03-14 ペンウェスト ファーマシューティカルズ カンパニー 高度に可溶性の薬物のための徐放性マトリックス系
DE60001487T2 (de) 2000-04-27 2003-12-24 Hu Oliver Yoa Pu Polynalbuphinderivat
US6525062B2 (en) 2000-06-09 2003-02-25 The Regents Of The University Of California Method of treating pain using nalbuphine and opioid antagonists
US6692771B2 (en) 2001-02-23 2004-02-17 Cima Labs Inc. Emulsions as solid dosage forms for oral administration
US20050176790A1 (en) 2001-02-28 2005-08-11 Johannes Bartholomaus Pharmaceutical salts
WO2002100382A2 (en) 2001-06-08 2002-12-19 Endo Pharmaceuticals, Inc. Controlled release dosage forms using acrylic polymer, and process for making the same
US6703398B2 (en) 2001-11-26 2004-03-09 Oliver Yoa-Pu Hu Orally administered analgesic compositions containing nalbuphine
EP1549296A4 (en) 2002-08-02 2006-08-09 Penwest Pharmaceuticals Co METFORMIN FORMULATIONS WITH DELAYED RELEASE
EP2959893A1 (en) 2002-12-13 2015-12-30 DURECT Corporation Oral drug delivery system comprising high viscosity liquid carrier materials
US20040224020A1 (en) 2002-12-18 2004-11-11 Schoenhard Grant L. Oral dosage forms with therapeutically active agents in controlled release cores and immediate release gelatin capsule coats
MXPA05009757A (es) 2003-03-13 2005-12-05 Controlled Chemicals Inc Conjugados de oxicodona con menor potencial de abuso y duracion de accion extendida.
CA2541371C (en) 2003-10-03 2014-12-16 Atul M. Mehta Extended release formulations of opioids and method of use thereof
US20050165038A1 (en) 2004-01-22 2005-07-28 Maxwell Gordon Analgetic dosage forms that are resistant to parenteral and inhalation dosing and have reduced side effects
EP1584335A3 (en) 2004-04-05 2006-02-22 Laboratorios Del Dr. Esteve, S.A. Active substance combination comprising a carbinol composition and an opioid
WO2005112926A1 (en) 2004-05-17 2005-12-01 Pharmacofore, Inc. Compositions and methods for treating or preventing pain

Also Published As

Publication number Publication date
US8771732B2 (en) 2014-07-08
EP2402005A1 (en) 2012-01-04
JP2009506059A (ja) 2009-02-12
WO2007025005A2 (en) 2007-03-01
WO2007025005A3 (en) 2007-12-21
ES2862573T3 (es) 2021-10-07
EP1931315B1 (en) 2013-10-16
CA2620224A1 (en) 2007-03-01
HUE053838T2 (hu) 2021-07-28
PT1931315E (pt) 2014-01-03
US20070048376A1 (en) 2007-03-01
PL2402005T3 (pl) 2021-11-22
US9186330B2 (en) 2015-11-17
CA2881739A1 (en) 2007-03-01
CA2620224C (en) 2015-11-24
US20140315937A1 (en) 2014-10-23
ES2441766T3 (es) 2014-02-06
EP1931315A2 (en) 2008-06-18
CA2881739C (en) 2018-01-02
EP2402005B1 (en) 2020-12-16
PT2402005T (pt) 2021-04-14
DK2402005T3 (da) 2021-03-15
DK1931315T3 (da) 2014-01-20

Similar Documents

Publication Publication Date Title
PT2402005T (pt) Formulações de libertação sustentada de nalbufina
IL246026A0 (en) Delayed release of anti-infectives
HK1200092A1 (en) Sustained release formulations
IL184460A0 (en) Sustained release pharmaeutical formulations
IL185800A0 (en) Controlled release formulations of octreotide
IL184822A0 (en) Extended release formulation of levetiracetam
EP1895991A4 (en) MODIFIED RELEASE FORMULATIONS OF ANTI-IRRITABLE DRUGS
GB0406819D0 (en) Controlled release compositions
IL188964A0 (en) Sustained drug release composition
EP1883406A4 (en) COMPOSITIONS AND METHOD FOR CONTINUOUS RELEASE OF BETA-ALLANINE
EP1765385A4 (en) IMPORTS COMPOSITION WITH DELAYED RELEASE
EP1714643A4 (en) PREPARATION WITH DELAYED RELEASE
ME01721B (me) Postupci za primjenu kompozicija aminopiridina sa produženim oslobađanjem
EP1802346A4 (en) PHARMACEUTICAL COMPOSITION WITH EXTENDED RELEASE
EP1951693A4 (en) SOLID FORMULATIONS
IL178383A0 (en) Delayed release formulations of 6-mercaptopurine
IL190865A0 (en) Formulations of quinolinones
ZA200705011B (en) Formulations of substituted benzoxazoles
IL177328A0 (en) Controlled release formulations
EP1871348A4 (en) PHARMACEUTICAL COMPOSITIONS WITH DELAYED RELEASE
IL198169A0 (en) Robust sustained release formulations of oxymorphone
ZA200803213B (en) Formulations of quinolinones
AP2006003706A0 (en) Controlled release pharmaceutical compositions