PL144582B2 - Method of improving properties of knitted artificial vessel implants made of polyester fibre - Google Patents

Method of improving properties of knitted artificial vessel implants made of polyester fibre Download PDF

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Publication number
PL144582B2
PL144582B2 PL25976186A PL25976186A PL144582B2 PL 144582 B2 PL144582 B2 PL 144582B2 PL 25976186 A PL25976186 A PL 25976186A PL 25976186 A PL25976186 A PL 25976186A PL 144582 B2 PL144582 B2 PL 144582B2
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PL
Poland
Prior art keywords
weight
polyester fibre
improving properties
implants made
artificial vessel
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Application number
PL25976186A
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Polish (pl)
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Priority to PL25976186A priority Critical patent/PL144582B2/en
Publication of PL144582B2 publication Critical patent/PL144582B2/en

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Description

Opis patentowy opublikowano: 89.05.312 144SB2 kazda, które przed,nasyceniem roztworem akryloaitiidu uprano w roztworze mydla, wyplukano kilkakrotnie woda i wysuszono. Próbki protez nasycano roztworem akryloamidu w ciagu 1 godziny w temperaturze 333 K i po ponownym ich wysuszeniu poddano je napromieniowaniu dawka promieniowania gamma 60 Co 25 kGy. Napromieniowane próbki ekstrahowano wielok¬ rotnie, w ciagu 48 godzin, woda o temperaturze 373 K i suszono do stalej masy.Zmodyfikowane w ten sposób protezy, zawierajace 8% wagowych poliakryloamidu, charakteryzowaly sie o 80% wyzsza hydrofilowoscia i 3 - krotnie lepsza szczelnoscia wporównaniu zproteza niemodyfikowana.Przyklad II.Przygotowano wodne roztwory akryloamidu firmy Fluka AG o stezeniach od 10 do 42% wagowych. Próbki protez naczyniowych z Bistom 56 dtex f24, uprzednio uprane w roztworze mydla, wyplukane woda i wysuszone, napawano uprzednio przygotowanymi roztwo¬ rami akryloamidu w ciagu 1 godziny, przy czym czescpróbek nasycano w temperaturze 291K, zas czesc w temperaturze 333 K. Wysuszone po napawaniu roztworem akryloamidu próbki napromie- niowywano nastepnie strumieniem elektronów z akceleratora stosujac dawki promieniowaniaod 4 do 50 kGy.Napromieniowanie próbki protez ekstahowano nastepnie wielokrotnie wrzaca woda i suszono do stalej masy.Zawartosc poliakryloamidu w modyfikowanych próbkach wynosila od 2 do 33,4% wagowych, w zaleznosci od stezeniaroztworuakryloamidu, temperatury napawania tym roztworem i stosowanej dawki promieniowania.Szczelnosc i hydrofilowosc scianek zmodyfikowanych w przykladzie II próbek protez przed¬ stawiono w tablicy podajac przepuszczalnosc wody przez scianki zmodyfikowanych protez o róznej zawartosci poliakryloamidu, zanurzonych przez caly czas trwania pomiarów w wodzie o temperaturze pokojowej. Dla porównania podano równiez przepuszczalnosc wody przez scianki protezy niemodyfikowanej. Przepuszczalnosc wody dla próbek o zawartosci 0-21% wagowych poliakryloamidu oznaczano przy cisnieniu 160 hPa, zas przepuszczalnosc wody dlaprotezy zawie¬ rajacej 33,4% wagowych poliakryloamidu oznaczano przy cisnieniu 190 hPa.Zawartosc poliakryloamidu . w protezie w % wagowych 0 2,0 8,6 11,8 19,8 21,3 33,4 0,5 h 3000 1400 1160 770 210 160 0 Tabl ica Przepuszczalnosc wody przez scianki 24h bez zmian 1600 1190 1290 270 340 0 w i ml/cm /min po' 7 dni bez zmian 1770 1000 1920 190 530 0 uplywie protez 17 dni bez zmian 1950 960 2280 230 550 0 28 dni bez zmian 1960 1160 2370 340 500 0 Jak wynika z tablicy 2% zawartosc poliakryloamidu powoduje 2 - krotny wzrost szczelnosci protez, zas okolo 10% zawartosc poliakryloamidu powoduje az 3-krotne zwiekszenie szczelnosci scianek protez. Przy zawartosci poliakryloamidu w protezie 33,4% wagowych sciankiprotezy byly calkowicie szczelne. Stwierdzono, iz wystarczaja poprawe szczelnosci i hydrofilowosci protezy zapewnia juz kilkuprocentowa zawartosc poliakryloamidu w protezie. Przekroczenie 10% zawar¬ tosci poliakryloamidu moze prowadzic do deformacji protezy. PLThe patent has been published: 89.05.312 144SB2 each, which before being saturated with acrylamide solution was washed in soap solution, rinsed several times with water and dried. Denture samples were saturated with acrylamide solution for 1 hour at the temperature of 333 K and, after being dried again, they were irradiated with a dose of gamma radiation 60 Co 25 kGy. The irradiated samples were extracted several times, within 48 hours, with water at 373 K and dried to constant mass. The modified prostheses, containing 8% by weight of polyacrylamide, were 80% more hydrophilic and 3 times better tight compared to prostheses. unmodified Example II Aqueous solutions of acrylamide from Fluka AG were prepared with concentrations ranging from 10 to 42% by weight. The samples of vascular prostheses from Bistom 56 dtex f24, previously washed in a soap solution, rinsed with water and dried, were padded with previously prepared acrylamide solutions for 1 hour, while some samples were saturated at 291K, and some at 333K. samples were then irradiated with the electron beam from the accelerator using radiation doses ranging from 4 to 50 kGy. Irradiation of the denture sample was then extracted several times with boiling water and dried to a constant mass. The content of polyacrylamide in the modified samples was from 2 to 33.4% by weight, depending on on the concentration of the acrylamide solution, the temperature of surfacing with this solution and the radiation dose used. The tightness and hydrophilicity of the walls of the modified denture samples in Example 2 are presented in the table with the information about the water permeability of the walls of modified prostheses with different polyacrylamide content, immersed for the entire duration of the measurements in water at room temperature. For comparison, the water permeability through the walls of the unmodified prosthesis is also given. Water permeability for samples containing 0-21% by weight of polyacrylamide was determined at a pressure of 160 hPa, while water permeability for a prosthesis containing 33.4% by weight of polyacrylamide was determined at a pressure of 190 hPa. Polyacrylamide content. in denture weight% 0 2.0 8.6 11.8 19.8 21.3 33.4 0.5 h 3000 1400 1160 770 210 160 0 Table Water permeability through walls 24h unchanged 1600 1190 1290 270 340 0 in ml / cm / min after 7 days no change 1770 1000 1920 190 530 0 expiration of prostheses 17 days no change 1950 960 2280 230 550 0 28 days no change 1960 1160 2370 340 500 0 As shown in the table 2% polyacrylamide content causes 2 - a fold increase in the tightness of dentures, and about 10% of the polyacrylamide content causes up to a threefold increase in the tightness of the walls of dentures. With a polyacrylamide content in the prosthesis of 33.4% by weight, the walls of the prosthesis were completely tight. It was found that a sufficient improvement in the tightness and hydrophilicity of the prosthesis is ensured by the content of polyacrylamide in the prosthesis by a few percent. Exceeding 10% of the polyacrylamide content may lead to deformation of the prosthesis. PL

Claims (1)

1. Zastrzezenia patentowe Sposób poprawy dzianych protez naczyniowych z poliestru, znamienny tym, ze protezy uprzednio wyprane, wyplukane i wysuszone, nasyca sie wodnym roztworem akryloamidu w temperaturze 303 - 3S3K w ciagu0,5 -1 godziny azdo uzyskania zawartosci akryloamidu wprotezie 10 -100%, korzystnie 15 - 65% wagowych masy protezy, ponownie suszy i poddaje napromienio¬ waniu promieniowaniem gamma lub przyspieszonymi elektronami stosujac dawke promieniowa¬ nia 4 - 50 kGy, po czym wrzaca woda i suszy do stalej masy. feracownia Poligraficzna UPPRL. Naklad 100 egz. Cena 400 zl PL1. Patent claims A method of improving knitted vascular prostheses made of polyester, characterized in that the prostheses previously washed, rinsed and dried are saturated with an aqueous solution of acrylamide at the temperature of 303-3S3K for 0.5-1 hour until the acrylamide content is 10-100% , preferably 15-65% by weight of the prosthesis weight, is dried again and irradiated with gamma radiation or accelerated electrons using a radiation dose of 4-50 kGy, followed by boiling water and drying to constant weight. Printing House UPPRL. Mintage 100 copies. Price PLN 400 PL
PL25976186A 1986-05-27 1986-05-27 Method of improving properties of knitted artificial vessel implants made of polyester fibre PL144582B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PL25976186A PL144582B2 (en) 1986-05-27 1986-05-27 Method of improving properties of knitted artificial vessel implants made of polyester fibre

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL25976186A PL144582B2 (en) 1986-05-27 1986-05-27 Method of improving properties of knitted artificial vessel implants made of polyester fibre

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PL144582B2 true PL144582B2 (en) 1988-06-30

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PL25976186A PL144582B2 (en) 1986-05-27 1986-05-27 Method of improving properties of knitted artificial vessel implants made of polyester fibre

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